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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Zilee AX 500mg/75mg Tablet is used to treat respiratory diseases associated with excess mucus. It contains Ambroxol and Levofloxacin which inhibit bacterial growth and thin & loosen mucus (phlegm), making it easier to cough. In some cases, this medicine may cause side effects such as nausea, vomiting, diarrhoea, headache, and dizziness. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Manufacturer/Marketer :

FDC Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

About Zilee AX 500mg/75mg Tablet

Zilee AX 500mg/75mg Tablet belongs to a class of drugs called 'respiratory stimulants' (cough/sputum thinner) primarily used to treat acute (short term) and chronic (long term) respiratory diseases associated with excess mucus. Acute respiratory diseases are initially associated with dry, irritating cough, hoarseness in laryngitis (swelling of the voice box), or burning sensation in the chest due to bronchitis (swelling of the lining of bronchial tubes). Then, wet mucus forms, and continuous coughing out of sputum occurs. In chronic respiratory diseases, dry irritating cough and wet cough with mucus occur.

Zilee AX 500mg/75mg Tablet consists of two medicines: Ambroxol (dilutes viscous cough) and Levofloxacin (antibiotic). Ambroxol is a mucolytic that thins and loosens mucus (phlegm), making it easier to cough. Levofloxacin comes into the category of antibiotic medicines that stop bacterial growth by inhibiting the two enzymes (bacterial topoisomerase IV and DNA gyrase) required for bacterial cell growth. As a result, bacterial cells are not able to reproduce and grow. It is a bacteriostatic antibiotic, i.e., it stops bacteria's growth but does not necessarily kill them. The addition of ambroxol enhances the antibacterial effect of levofloxacin.

Zilee AX 500mg/75mg Tablet should be taken as advised by your doctor. Take Zilee AX 500mg/75mg Tablet with/without food and swallow whole with a glass of water. Do not crush, chew, or break it. Some people may experience common side effects like nausea, vomiting, diarrhea, headache, dizziness, insomnia (difficulty sleeping), and allergic reactions. Most of these side effects of Zilee AX 500mg/75mg Tablet do not require medical attention and gradually resolve over time. If you experience any allergic reaction (rashes, itching, swelling, shortness of breath, etc.), you must seek immediate medical help.

Before taking this Zilee AX 500mg/75mg Tablet, you should tell your doctor if you are taking any medicines other than Zilee AX 500mg/75mg Tablet. Before taking Zilee AX 500mg/75mg Tablet, inform your doctor if you have liver and kidney diseases. If you are pregnant or breastfeeding, consult your doctor before taking Zilee AX 500mg/75mg Tablet. Zilee AX 500mg/75mg Tablet should be used with caution in gastric ulcer patients, epilepsy, and muscle disorders. Avoid drinking alcohol as it can cause excessive drowsiness with this Zilee AX 500mg/75mg Tablet.

Uses of Zilee AX 500mg/75mg Tablet

Treatment of Respiratory tract infection

Directions for Use

• Zilee AX 500mg/75mg Tablet can be taken with or without food as advised by your doctor.• Follow your doctor's instructions on the dosage and timing of this medication.• Swallow Zilee AX 500mg/75mg Tablet as a whole with a glass of water.• Do not crush, break, or chew it.

Medicinal Benefits

Zilee AX 500mg/75mg Tablet consists of two medicines, namely: Ambroxol (dilutes viscous cough) and Levofloxacin (antibiotic), belongs to a class of drugs called 'respiratory stimulants' primarily used to treat acute (short term) and chronic (long term) respiratory diseases associated with excess mucus. Ambroxol is a mucolytic that thins and loosens mucus (phlegm), making it easier to cough out. Levofloxacin comes into the category of antibiotic medicines that stop bacterial growth by inhibiting the two enzymes (bacterial topoisomerase IV and DNA gyrase) required for bacterial cell growth. As a result, bacterial cells are not able to reproduce and grow. It is a bacteriostatic antibiotic, i.e., it stops bacteria's growth but does not necessarily kill them. The addition of ambroxol enhances the antibacterial effect of levofloxacin.

How Zilee AX 500mg/75mg Tablet Works

Zilee AX 500mg/75mg Tablet consists of two medicines: Ambroxol (dilutes viscous cough) and Levofloxacin (antibiotic). Ambroxol is a mucolytic that thins and loosens mucus (phlegm), making it easier to cough. Levofloxacin comes into the category of antibiotic medicines that stop bacterial growth by inhibiting the two enzymes (bacterial topoisomerase IV and DNA gyrase) required for bacterial cell growth. As a result, bacterial cells are not able to reproduce and grow. It is a bacteriostatic antibiotic, i.e., it stops bacteria's growth but does not necessarily kill them. The addition of ambroxol enhances the antibacterial effect of levofloxacin.

Storage

stored at room temperature below 30°C

What if I have taken an overdose of Zilee AX 500mg/75mg Tablet

Avoid exceeding the recommended dose as it might cause an overdose. Seek immediate medical attention if you experience any unusual symptoms.

Drug Warnings

Before taking this Zilee AX 500mg/75mg Tablet, you should tell your doctor if you are taking any medicines other than Zilee AX 500mg/75mg Tablet. Before taking Zilee AX 500mg/75mg Tablet, inform your doctor if you have liver and kidney diseases. Pregnant or breastfeeding women should also consult their doctor before taking Zilee AX 500mg/75mg Tablet. Zilee AX 500mg/75mg Tablet should be used with caution in gastric ulcer patients, epilepsy, and muscle disorders. Avoid drinking alcohol as it can cause excessive drowsiness with this Zilee AX 500mg/75mg Tablet. During the treatment, you must take adequate rest for a faster recovery. While on the medication, your doctor may ask for a few laboratory and diagnostic tests to know the effects of Zilee AX 500mg/75mg Tablet on your body.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Zilee AX 500mg/75mg Tablet:
Taking Zilee AX 500mg/75mg Tablet with Ziprasidone can increase the risk of abnormal heart rhythm.

How to manage the interaction:
Taking Zilee AX 500mg/75mg Tablet with Ziprasidone is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Zilee AX 500mg/75mg Tablet:
The combination of Amiodarone and Zilee AX 500mg/75mg Tablet may significantly raise the risk of an abnormal heart rhythm.

How to manage the interaction:
Despite the fact that Amiodarone and Zilee AX 500mg/75mg Tablet interact, it can be taken if prescribed by a doctor. If you get dizziness, lightheadedness, fainting, or fast or racing heartbeats, consult a doctor. Do not stop taking any medications without visiting a doctor.
How does the drug interact with Zilee AX 500mg/75mg Tablet:
Combining Zilee AX 500mg/75mg Tablet with Disopyramide can increase the risk of irregular heart rhythm .

How to manage the interaction:
Taking Zilee AX 500mg/75mg Tablet with Disopyramide is not recommended, as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, or fast or pounding heartbeats, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
How does the drug interact with Zilee AX 500mg/75mg Tablet:
Using sotalol together with Zilee AX 500mg/75mg Tablet can increase the risk of an irregular heart rhythm that may be serious. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Zilee AX 500mg/75mg Tablet with Sotalol is generally avoided as it can result in an interaction, it can be taken if your doctor has advised it. If you experience sudden dizziness, lightheadedness, fainting, or fast or pounding heartbeats, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Zilee AX 500mg/75mg Tablet:
Co-administration of Zilee AX 500mg/75mg Tablet with Glibenclamide may affect blood glucose levels.

How to manage the interaction:
Although there is a possible interaction, glibenclamide can be taken with Zilee AX 500mg/75mg Tablet if prescribed by the doctor. Consult the prescriber if you experience nervousness, confusion, headache, dizziness, drowsiness, tremors, nausea, hunger, weakness, perspiration, pulse, rapid heartbeat, increased urination, increased thirst, and increased hunger. Monitoring of blood glucose levels is advised. Do not discontinue the medications without consulting a doctor.
How does the drug interact with Zilee AX 500mg/75mg Tablet:
Coadministration of Zilee AX 500mg/75mg Tablet and Insulin degludec can sometimes affect blood glucose levels - Both hyperglycemia (high blood glucose) and, less frequently, hypoglycemia (low blood glucose).

How to manage the interaction:
Although using Zilee AX 500mg/75mg Tablet and insulin degludec at the same time may cause an interaction, they can be taken together if a doctor has prescribed it. Inform doctor if you develop hypoglycemia (low blood glucose) or hyperglycemia (high blood glucose), or if you have trouble controlling your blood glucose. Hypoglycemia symptoms include headache, dizziness, tiredness, anxiety, disorientation, a shaking sensation, nausea, hunger, weakness, sweating, palpitation, and a rapid pulse. Hyperglycemia symptoms include Increased thirst, increased hunger, and increased urination. Do not stop using any medications without talking to a doctor.
How does the drug interact with Zilee AX 500mg/75mg Tablet:
Coadministration of Zilee AX 500mg/75mg Tablet and Leflunomide can increase the risk of liver issues.

How to manage the interaction:
Although concomitant administration of Zilee AX 500mg/75mg Tablet alongside leflunomide can result in an interaction, it can be taken if a doctor has advised it. However, if you have a fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark-colored urine, light-colored stools, and/or yellowing of the skin or eyes, contact the doctor right away. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Zilee AX 500mg/75mg Tablet:
Co-administration of Zilee AX 500mg/75mg Tablet and Bempedoic acid can increase the risk of tissue injury near muscles and joints.

How to manage the interaction:
Although there is an interaction, Bempedoic acid can be taken with Zilee AX 500mg/75mg Tablet if prescribed by the doctor. However, if you experience pain, swelling, or inflammation of joints, consult a doctor. Exercise and using the impacted area should both be avoided. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Zilee AX 500mg/75mg Tablet:
Taking Zilee AX 500mg/75mg Tablet with efavirenz increases the risk of an abnormal heart rhythm.

How to manage the interaction:
Concomitant administration of Zilee AX 500mg/75mg Tablet with efavirenz can result in an interaction, it can be taken if a doctor has advised it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, get medical help immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Zilee AX 500mg/75mg Tablet:
Taking Zilee AX 500mg/75mg Tablet with escitalopram increases the risk of an abnormal heart rhythm.

How to manage the interaction:
Concomitant administration of Zilee AX 500mg/75mg Tablet with escitalopram can result in an interaction, it can be taken if a doctor has advised it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, get medical help immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Take Zilee AX 500mg/75mg Tablet as directed by the doctor and at regular intervals. Do not use other over-the-counter medications, herbal or vitamin supplements without informing your pharmacist or doctor when you take Zilee AX 500mg/75mg Tablet.
  • Know your triggers, like allergens, such as pollen, dust, and food items, that make your condition severe.
  • Quit smoking and avoid passive smoking. Smoking also reduces the effectiveness of the medicine.
  • Eat a healthy diet and exercise regularly to strengthen your breathing muscles and boost your immune system.
  • Learning breathing exercises will help you move more air in and out of your lungs.
  • Drink warm fluids while you take Zilee AX 500mg/75mg Tablet to help loosen congestion and lubricate the throat.

Habit Forming

No

Therapeutic Class

RESPIRATORY STIMULANTS
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Alcohol

Caution

Zilee AX 500mg/75mg Tablet with alcohol may cause unpleasant effects. So please consult your doctor before taking Zilee AX 500mg/75mg Tablet.

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Pregnancy

Unsafe

Zilee AX 500mg/75mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits outweigh the potential risks. So please consult your doctor before taking Zilee AX 500mg/75mg Tablet.

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Breast Feeding

Caution

Zilee AX 500mg/75mg Tablet should be used with caution in breastfeeding mothers as it may cause risk to the baby through breast milk. So please consult your doctor before taking Zilee AX 500mg/75mg Tablet.

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Driving

Caution

Zilee AX 500mg/75mg Tablet may decrease alertness and affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

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Liver

Caution

Zilee AX 500mg/75mg Tablet should be used with caution in patients with liver disease. A dose adjustment of Zilee AX 500mg/75mg Tablet may be needed. Please consult your doctor before taking Zilee AX 500mg/75mg Tablet.

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Kidney

Caution

Zilee AX 500mg/75mg Tablet should be used with caution in patients with kidney disease. A dose adjustment of Zilee AX 500mg/75mg Tablet may be needed. Please consult your doctor before taking Zilee AX 500mg/75mg Tablet.

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Children

Caution

Zilee AX 500mg/75mg Tablet should be used with caution in children because dose adjustments were made by your doctor based on the children's height and weight. So please consult your doctor before taking Zilee AX 500mg/75mg Tablet.

Have a query?

FAQs

Zilee AX 500mg/75mg Tablet is used to treat respiratory tract infections.

Zilee AX 500mg/75mg Tablet consists of two medicines: Ambroxol (dilutes viscous cough) and Levofloxacin (antibiotic). Ambroxol is a mucolytic that thins and loosens mucus (phlegm), making it easier to cough. Levofloxacin is an antibiotic that stops bacterial growth by inhibiting the two enzymes (bacterial topoisomerase IV and DNA gyrase) required for bacterial cell growth. The addition of ambroxol enhances the antibacterial effect of levofloxacin.

Zilee AX 500mg/75mg Tablet may cause common side effects like nausea, vomiting, diarrhea, headache, dizziness, insomnia (difficulty in sleeping), and allergic reactions. Most of these side effects of Zilee AX 500mg/75mg Tablet do not require medical attention and gradually resolve over time. If you experience any allergic reaction (rashes, itching, swelling, shortness of breath, etc.), you must seek immediate medical help.

Do not stop taking Zilee AX 500mg/75mg Tablet even if you feel better because you may feel better by the action of Zilee AX 500mg/75mg Tablet before the infection is completely cured.

It is advised to tell your doctor if using contraceptives to prevent pregnancy as Zilee AX 500mg/75mg Tablet may make contraceptives less effective.

Zilee AX 500mg/75mg Tablet should not be taken in patients with seizures or fits as it might worsen your condition. So please consult your doctor before taking Zilee AX 500mg/75mg Tablet.

Inform your doctor if your symptoms are not relieved after completing the full course of Zilee AX 500mg/75mg Tablet. If you notice any undesirable effects that bother you while taking Zilee AX 500mg/75mg Tablet, consult your doctor.

If you miss taking a dose Zilee AX 500mg/75mg Tablet, then take it as soon as you remember and if it is the time for the next dose, skip the missed dose and continue with the regular dose. Avoid taking more to make up for the missed one.

Zilee AX 500mg/75mg Tablet causes side effects such as nausea, vomiting, diarrhoea, headache, dizziness, insomnia (difficulty in sleeping), acute kidney failure, allergic reactions, and arrhythmia. Please consult a doctor immediately if any of these side effects persist longer.

Country of origin

India

Manufacturer/Marketer address

212/2, Hadapsar, Off Soli Poonawalla Road, Pune 411028 India.
Other Info - ZI67090

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