Zestonide 0.5 mg Respules | Uses, Side Effects, Price

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Prescription Medicine

Zestonide 0.5 mg Respules is used to relieve symptoms of asthma and COPD (Chronic Obstructive Pulmonary Disease). It contains Budesonide, which works by blocking the production of certain chemical messengers that are involved in inflammation. Thereby, it helps to treat inflammatory diseases. It decreases inflammation and irritation in the airways and makes breathing easier. Thus, it provides relief from the symptoms of asthma and COPD. It may cause certain common side effects like indigestion, headache, abdominal pain, nausea, bloating, constipation, gas, vomiting, stuffy nose, tiredness/weakness, and sore throat.

Written By Lakshmithulasi Yarragunta ,

Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy

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More about the Product

Composition :

BUDESONIDE-0.5MG

Manufacturer/Marketer :

Nutrilis Healthcare Pvt Ltd

Consume Type :

Inhalation

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Zestonide 0.5 mg Respules

Zestonide 0.5 mg Respules is used to relieve symptoms of asthma and COPD (Chronic Obstructive Pulmonary Disease). Asthma is a chronic (long-term) respiratory condition in which airways narrow, swell, and produce extra mucus, leading to difficulty breathing. COPD is a group of lung diseases that causes obstructed airflow from the lungs.

Zestonide 0.5 mg Respules contains Budesonide. It works by blocking the production of certain chemical messengers that are involved in allergic and non-allergic-mediated inflammation. Thereby, Zestonide 0.5 mg Respules helps treat inflammatory diseases. Zestonide 0.5 mg Respules decreases inflammation and irritation in the airways and makes breathing easier. Thus, it provides relief from the symptoms of asthma and COPD.

Your doctor will decide the dose and duration based on your medical condition. In some cases, Zestonide 0.5 mg Respules may cause certain common side effects like indigestion, headache, abdominal pain, nausea, bloating, constipation, gas, vomiting, stuffy nose, tiredness/weakness, and sore throat. These side effects generally do not require medical attention and typically subside with time. However, talk to your doctor if you experience any of the side effects persistently.

Avoid using Zestonide 0.5 mg Respules if you are allergic to it. Consult your doctor before using Zestonide 0.5 mg Respules if you are pregnant or breastfeeding. Generally, Zestonide 0.5 mg Respules does not alter your ability to drive, but in some cases, it may cause dizziness, so drive only if you are alert. Zestonide 0.5 mg Respules is recommended for children only with a doctor's advice. The interaction of Zestonide 0.5 mg Respules with alcohol is unknown; therefore, consult a doctor if you have any concerns. Keep your doctor informed about your health condition and medications to rule out any interactions.

Uses of Zestonide 0.5 mg Respules

Zestonide 0.5 mg Respules is used in the treatment of asthma and chronic obstructive pulmonary disease. The detailed uses of Zestonide 0.5 mg Respules are as follows:

Management of Asthma: Zestonide 0.5 mg Respules is often used as a maintenance therapy for individuals with asthma to reduce inflammation in the airways and improve breathing.
Chronic Obstructive Pulmonary Disease (COPD): Zestonide 0.5 mg Respules can help manage symptoms and improve lung function in patients with COPD, alleviating breathlessness and wheezing.
Respiratory Emergencies: In cases of acute exacerbations of chronic respiratory diseases, Zestonide 0.5 mg Respules can be utilised to provide prompt relief from inflammation.
Post-Surgical Airway Management: After specific surgical procedures involving the airways, Zestonide 0.5 mg Respules may be used to minimise swelling and ensure a clear airway for recovery.

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Directions for Use

Follow your doctor's instructions on the dosage and timing of this medication to ensure safe and effective use.
Hold Zestonide 0.5 mg Respules with the mouthpiece downwards. Put the mouthpiece between your teeth and seal the lips around it. Then, press down on the inhaler once to release the medication. Breathe in slowly and hold your breath for 5 to 10 seconds. Breathe out slowly. Repeat the process until you have inhaled the number of puffs prescribed by the doctor.
Rinse your mouth with water and spit it out after using Zestonide 0.5 mg Respules to avoid fungal infections in the mouth and throat.

Key Benefits

Zestonide 0.5 mg Respules contains Budesonide, a glucocorticosteroid that helps reduce inflammation in the airways and improves overall lung function.
It is mainly prescribed for the treatment of asthma and chronic obstructive pulmonary disease (COPD), allowing patients to breathe more comfortably and preventing frequent flare-ups.
Zestonide 0.5 mg Respules works by blocking the release of inflammatory substances in the lungs, calming the body’s overactive immune response, and reducing airway swelling.
It effectively helps control asthma symptoms, including wheezing, chest tightness, and difficulty breathing, when used regularly as a maintenance therapy.
In COPD, Zestonide 0.5 mg Respules improves lung function, reducing persistent coughing, breathlessness, and other breathing difficulties caused by airway inflammation.
During respiratory emergencies or sudden worsening of chronic respiratory diseases, it provides fast relief by decreasing inflammation and opening the airways.
After certain airway-related surgeries, Zestonide 0.5 mg Respules may be prescribed to minimise post-surgical swelling, maintain clear airways, and support a smooth recovery.

How Zestonide 0.5 mg Respules Works

Storage

Store in a cool and dry place away from sunlight

Side effects of Zestonide 0.5 mg Respules

Respiratory Infection

Nausea

Overcome Medication-Induced Nausea: A 9-Step Plan

Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
Divide your daily food intake into smaller, more frequent meals to reduce nausea.
Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
Use ginger (tea, ale, or candies) to help relieve nausea.
Get adequate rest and also avoid strenuous activities that can worsen nausea.
Talk to your doctor about taking anti-nausea medication if your nausea is severe.
Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.

Stomach Pain

Drink water or other clear fluids.
To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
Include bland foods like rice, toast, crackers, and rice in your diet.
Avoid lying down immediately after eating as it may cause indigestion or heartburn.
Avoid acidic and spicy food as it may cause indigestion.

Headache

Dealing with Medication-Induced Headache:

Hydrate your body: Drink enough water to prevent dehydration and headaches.
Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
Take rest: lie down in a quiet, dark environment.
Cold or warm compresses can help reduce tension.
Stay Upright: Maintain good posture to keep symptoms from getting worse.
To treat headaches naturally, try acupuncture or massage therapy.
Over-the-counter pain relievers include acetaminophen and ibuprofen.
Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
Frequent Headaches: If you get reoccurring headaches, consult your doctor.
Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.

Involuntary Contractions Of A Muscle

Gently massage the affected area using your hands or a massager.
Light exercises such as walking or climbing stairs may help the muscles return to normal.
Apply heat/ice to the affected area.
Drink electrolyte-rich fluids.

Swelling In The Feet And Ankles

Wear compression garments like stockings, sleeves, or gloves to apply pressure and help stop fluid from building up, especially after the swelling goes down.
Move around and do exercises to help the fluid circulate, especially in swollen limbs. Ask your doctor for specific exercises.
Raise the swollen area above your heart level several times a day, even while sleeping, to help reduce swelling.
Gently massage the swollen area with firm but not painful pressure.
Keep the swollen area clean and moisturized to prevent injury and infection.
Reduce salt intake to help prevent fluid from building up and worsening the swelling, as advised by a doctor.
If the swelling does not get better after a few days of home treatment or worsens, consult your doctor right away.

Pimples

Keep your skin clean by gently washing your face two times daily and after sweating. Choose a mild and non-abrasive cleanser.
Use gentle alcohol-free skin care products. Avoid products that might irritate your skin such as exfoliants, astringents and toners.
Acne may also occur due to oil in the hair. Thus, if you have oily hair, shampoo more frequently than you do now and keep your hair away from face.
Keep your hands off your face as touching face throughout the day might worsen acne. Also, do not pick, squeeze or pop acne as it will prolong the healing process and increase the risk of dark spots and scarring.
Avoid tanning by applying a broad spectrum sunscreen and wearing sun-protective clothing when outdoors.

What if I have taken an overdose of Zestonide 0.5 mg Respules

Do not use Zestonide 0.5 mg Respules in more doses or more often than prescribed. If you have any unusual signs or symptoms, please consult a doctor immediately.

Drug Warnings

Do not use Zestonide 0.5 mg Respules if you are allergic to Budesonide or any other ingredient in this medicine.
Avoid using Zestonide 0.5 mg Respules if you have severe liver disease. Patients with moderate liver impairment should only use it under close medical supervision.
Inform your doctor if you have or have ever had tuberculosis, chronic infections, high blood pressure, diabetes, osteoporosis, stomach ulcers, glaucoma, cataracts, eczema, kidney problems, or a weakened immune system.
Tell your doctor if you have been previously treated with potent corticosteroids or have had recent nasal surgery, ulcers, or trauma in the airways, as these conditions may require extra monitoring.
Use Zestonide 0.5 mg Respules during pregnancy or breastfeeding only if recommended and monitored by a healthcare professional.
This medicine may occasionally cause dizziness or blurred vision. Avoid driving or operating machinery until you know how it affects you.
Zestonide 0.5 mg Respules should only be used in children under a doctor’s advice, with regular monitoring for growth and side effects.

Drug-Drug Interactions

BudesonideRibociclib

Critical

BudesonideMifepristone

Critical

Drug-Drug Interactions

BudesonideRibociclib

Critical

How does the drug interact with Zestonide 0.5 mg Respules:
Coadministration of Zestonide 0.5 mg Respules and Ribociclib may increase the absorption of the medication from Zestonide 0.5 mg Respules into the blood stream.

How to manage the interaction:
Taking Ribociclib with Zestonide 0.5 mg Respules can cause an interaction, consult a doctor before taking it. Consult a doctor if experience swelling, weight gain, high blood pressure, high blood glucose, muscle weakness, depression, acne, thinning skin, stretch marks, easy bruising, bone density loss, cataracts, menstrual irregularities, excessive growth of facial or body hair, and abnormal distribution of body fat, especially in the face, neck, back, and waist. Do not stop using any medications without talking to a doctor.

BudesonideMifepristone

Critical

How does the drug interact with Zestonide 0.5 mg Respules:
Using mifepristone together with Zestonide 0.5 mg Respules may significantly reduce the effects of Zestonide 0.5 mg Respules.

How to manage the interaction:
Taking Zestonide 0.5 mg Respules with Mifepristone is not recommended as it can cause an interaction, but it can be taken if prescribed by the doctor. Do not stop using any medications without talking to a doctor.

BudesonidePosaconazole

Severe

How does the drug interact with Zestonide 0.5 mg Respules:
Taking Zestonide 0.5 mg Respules with posaconazole can increase the blood levels of Zestonide 0.5 mg Respules, which may lead to side effects.

How to manage the interaction:
Although there is an interaction between posaconazole and Zestonide 0.5 mg Respules, it can be taken if recommended by a doctor. However, if you experience swelling, weight gain, muscle weakness, depression, acne, thinning skin, stretch marks, easy bruising, vision problems, menstrual irregularities, excessive growth of facial or body hair, and abnormal distribution of body fat, especially in the face, neck, back, and waist, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.

BudesonideIndinavir

Severe

How does the drug interact with Zestonide 0.5 mg Respules:
When Zestonide 0.5 mg Respules is taken with Indinavir, may considerably enhance Zestonide 0.5 mg Respules absorption into the bloodstream which may lead to side effects.

How to manage the interaction:
Co-administration of Zestonide 0.5 mg Respules along with Indinavir can lead to an interaction, it can be taken if recommended by a doctor. However, if you experience swelling, weight gain, high blood pressure, high blood glucose, muscle weakness, depression, acne, thinning skin, stretch marks, easy bruising, bone density loss, vision problems, menstrual irregularities, excessive growth of facial or body hair, and abnormal distribution of body fat, especially in the face, neck, back, and waist, infections, a severe asthma attack, consult the doctor immediately. Do not stop using any medications without talking to a doctor.

BudesonideEtanercept

Severe

How does the drug interact with Zestonide 0.5 mg Respules:
When Etanercept is used with Zestonide 0.5 mg Respules, the severity of infection may increase.

How to manage the interaction:
Co-administration of Zestonide 0.5 mg Respules with Etanercept can result in an interaction, but it can be taken if a doctor has advised it. However, if you develop fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.

BudesonideTofacitinib

Severe

How does the drug interact with Zestonide 0.5 mg Respules:
Using tofacitinib together with Zestonide 0.5 mg Respules may increase the risk of serious infections.

How to manage the interaction:
Co-administration of Zestonide 0.5 mg Respules along with tofacitinib can lead to an interaction but can be taken together if prescribed by a doctor. However, consult a doctor if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue any medications without consulting a doctor.

BudesonideFingolimod

Severe

How does the drug interact with Zestonide 0.5 mg Respules:
When Zestonide 0.5 mg Respules is used with fingolimod, the risk of severe infections increases.

How to manage the interaction:
Co-administration of Zestonide 0.5 mg Respules along with fingolimod can lead to an interaction, it can be taken if recommended by a doctor. However, if you develop a fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in sputum, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult the doctor as soon as possible. Do not discontinue any medications without consulting a doctor.

BudesonideInfliximab

Severe

How does the drug interact with Zestonide 0.5 mg Respules:
Coadministration of Zestonide 0.5 mg Respules and Infliximab can increase the risk or severity of developing serious infections.

How to manage the interaction:
There may be a possibility of interaction between Zestonide 0.5 mg Respules and Infliximab, but it can be taken if prescribed by a doctor. However, if you have any of these symptoms like fever, chills, diarrhea, sore throat, muscle aches, difficulty breathing, weight loss, and pain or burning when you pee, it's important to contact a doctor right away. Do not stop using any medications without talking to a doctor.

BudesonideCobicistat

Severe

How does the drug interact with Zestonide 0.5 mg Respules:
When Zestonide 0.5 mg Respules is taken with Cobicistat, may considerably enhance Zestonide 0.5 mg Respules absorption into the bloodstream which may lead to side effects.

How to manage the interaction:
Co-administration of Zestonide 0.5 mg Respules along with cobicistat can lead to an interaction, it can be taken if recommended by a doctor. However, if you experience swelling, weight gain, high blood pressure, high blood glucose, muscle weakness, depression, acne, thinning skin, stretch marks, easy bruising, bone density loss, vision problems, menstrual irregularities, excessive growth of facial or body hair, and abnormal distribution of body fat, especially in the face, neck, back, and waist, infections, a severe asthma attack, consult the doctor immediately. Do not stop using any medications without talking to a doctor.

BudesonideIdelalisib

Severe

How does the drug interact with Zestonide 0.5 mg Respules:
When Zestonide 0.5 mg Respules is taken with Idelalisib, may considerably enhance Zestonide 0.5 mg Respules absorption into the bloodstream which may lead to side effects.

How to manage the interaction:
Co-administration of Zestonide 0.5 mg Respules along with Idelalisib can lead to an interaction, it can be taken if recommended by a doctor. However, if you experience swelling, weight gain, high blood pressure, high blood glucose, muscle weakness, depression, acne, thinning skin, stretch marks, easy bruising, bone density loss, vision problems, menstrual irregularities, excessive growth of facial or body hair, and abnormal distribution of body fat, especially in the face, neck, back, and waist, infections, a severe asthma attack, consult the doctor immediately. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

Diet & Lifestyle Advise

Eat a healthy diet and exercise regularly to strengthen your breathing muscles and boost your immune system.
Avoid foods such as cabbage, beans, garlic, onions, shrimp, pickled food, dried fruits, fried foods, carbonated drinks, wine, and bottled lemon and lime juice, as they may worsen asthma symptoms.
Know your triggers, such as allergens, like pollen, dust, and food items, that make your asthma severe.
Do meditation, deep breathing, regular exercise, and try progressive muscle relaxation techniques to get relief from stress and reduce the risk of an asthma attack.
Quit smoking as it may reduce the effectiveness of Zestonide 0.5 mg Respules and irritate the lungs, worsening breathing problems.
Learning breathing exercises will help you breathe more effectively.

Habit Forming

Therapeutic Class

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Alcohol

Unsafe

It is advisable to avoid or limit the intake of alcohol while you use Zestonide 0.5 mg Respules as it may cause increased dizziness.

Pregnancy

Consult your doctor

Please consult your doctor before using Zestonide 0.5 mg Respules if you are pregnant. Your doctor will prescribe only if the benefits outweigh the risks.

Breast Feeding

Consult your doctor

Please consult your doctor before using Zestonide 0.5 mg Respules if you are breastfeeding. Your doctor will decide if Zestonide 0.5 mg Respules can be used by breastfeeding mothers or not.

Driving

Caution

Generally, Zestonide 0.5 mg Respules does not alter your ability to drive, but in some cases, it may cause dizziness, so drive only if you are alert.

Liver

Consult your doctor

Please consult your doctor before using Zestonide 0.5 mg Respules if you have a liver impairment or any concerns regarding this.

Kidney

Consult your doctor

Please consult your doctor before using Zestonide 0.5 mg Respules if you have a kidney impairment or any concerns regarding this.

Children

Consult your doctor

Zestonide 0.5 mg Respules is recommended for children below 12 years only when prescribed by a doctor.

Heart

Consult your doctor

Please consult your doctor before using Zestonide 0.5 mg Respules if you have any pre-existing heart disease.

Geriatrics

Caution

Zestonide 0.5 mg Respules should be used with caution in elderly patients, as dose adjustments or monitoring may be necessary due to age-related health conditions.

FAQs

What is the use of Zestonide 0.5 mg Respules?

Zestonide 0.5 mg Respules is used to relieve symptoms of asthma and COPD (Chronic Obstructive Pulmonary Disease).

How does Zestonide 0.5 mg Respules work?

Zestonide 0.5 mg Respules decreases inflammation and irritation in the airways and makes it easier to breathe. Thus, it provides relief from the symptoms of asthma and COPD.

Can I take antacids with Zestonide 0.5 mg Respules?

Maintain a gap of two hours between medicines such as cholestyramine (a drug used to treat high cholesterol), antacids and Zestonide 0.5 mg Respules as they might increase the effects of Zestonide 0.5 mg Respules. However, you are advised to use Zestonide 0.5 mg Respules with other medicines only after consulting your doctor.

Do I need to avoid any foods while using Zestonide 0.5 mg Respules?

Grapefruit may alter the effects of Zestonide 0.5 mg Respules. Therefore, avoid the use of grapefruit and its products whilst using Zestonide 0.5 mg Respules.

Country of origin

India

Manufacturer/Marketer address

Satellite Ahmedabad Gujarat

Other Info - ZES0054

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Author Details

Reviewed By

Bayyarapu Mahesh Kumar

M Pharmacy

Last Updated

Apr 3, 2026 | 11:36 AM IST

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