Zerodol 150 mg Injection 1 ml

Prescription drug

MRP ₹119

(Inclusive of all Taxes)

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Written By Santoshini Reddy G , M Pharmacy

Reviewed By Veda Maddala , M Pharmacy

Zerodol 150 mg Injection 1 ml contains aceclofenac which is an NSAID (Non-Steroidal Anti-Inflammatory Drugs) medicine. It is mainly used to relieve pain, swelling, and stiffness caused by osteoarthritis, ankylosing spondylitis, and rheumatoid arthritis (inflammation of the joints). It is sometimes also used to reduce back pain. This medicine inhibits cyclo-oxygenase (COX) enzymes and this helps reduce pain.

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About Zerodol 150 mg Injection 1 ml

Zerodol 150 mg Injection 1 ml belongs to a group of medicines called Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) or pain killers used to reduce and relieve pain, and inflammation (swelling) associated with osteoarthritis, rheumatoid arthritis and ankylosing spondylitis. Zerodol 150 mg Injection 1 ml may also be indicated in the treatment of pain associated with post-traumatic and post-operative cases.

Zerodol 150 mg Injection 1 ml contains 'Aceclofenac' which works by blocking the effect of a chemical messenger known as cyclo-oxygenase (COX) enzyme that makes other chemical prostaglandins. By blocking the effect of COX enzymes, lesser prostaglandins are produced. This helps in reducing mild to moderate pain and inflammation at the injured or damaged site.

In some cases, Zerodol 150 mg Injection 1 ml may cause certain common side-effects such as vomiting, dizziness, nausea, abdominal pain, and diarrhoea. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Zerodol 150 mg Injection 1 ml may cause dizziness, so avoid driving or operating machinery unless you are alert. Zerodol 150 mg Injection 1 ml is not recommended for use during pregnancy, breastfeeding and in children. Avoid consuming alcohol along with Zerodol 150 mg Injection 1 ml as it could lead to increased dizziness. Keep your doctor informed about your health condition and medicines to rule out any side effects.

Uses of Zerodol 150 mg Injection 1 ml

Zerodol 150 mg Injection 1 ml is used to relieve pain and inflammation associated with various joint and musculoskeletal conditions. The detailed uses of Zerodol 150 mg Injection 1 ml are as follows:

Treatment of osteoarthritis: Zerodol 150 mg Injection 1 ml helps reduce joint pain, stiffness, and swelling in patients with osteoarthritis by relieving inflammation in the affected joints.
Management of rheumatoid arthritis: Zerodol 150 mg Injection 1 ml is effective in treating pain and inflammation caused by rheumatoid arthritis, an autoimmune condition that leads to joint damage and reduced mobility.
Relief in ankylosing spondylitis:Zerodol 150 mg Injection 1 ml is used to manage chronic pain and stiffness in the spine and lower back caused by ankylosing spondylitis, a form of inflammatory arthritis affecting the spine.

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Directions for Use

Follow your doctor’s instructions on the dosage and timing of this medication to ensure safe and effective use.
Zerodol 150 mg Injection 1 ml will be administered by the doctor or healthcare professional.
Do not self-administer.

Medicinal Benefits

Zerodol 150 mg Injection 1 ml belongs to a group of medicines called Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) used to reduce and relieve pain, and inflammation (swelling) in patients suffering from osteoarthritis, rheumatoid arthritis and ankylosing spondylitis. Zerodol 150 mg Injection 1 ml works by blocking the effect of a chemical messenger known as cyclo-oxygenase (COX) enzyme that makes other chemical prostaglandins which are produced at injury sites and cause pain and swelling. By blocking the effect of COX enzymes, lesser prostaglandins are produced. This helps in reducing mild to moderate pain and inflammation at the injured or damaged site. Zerodol 150 mg Injection 1 ml may also be indicated in the treatment of pain associated with post-traumatic and post-operative cases.

How Zerodol 150 mg Injection 1 ml Works

Zerodol 150 mg Injection 1 ml contains 'Aceclofenac' which works by blocking the effect of a chemical messenger known as cyclo-oxygenase (COX) enzyme that makes other chemical prostaglandins. By blocking the effect of COX enzymes, lesser prostaglandins are produced. This helps in reducing mild to moderate pain and inflammation at the injured or damaged site.

Storage

• Store in a cool and dry place away from sunlight.• Keep Zerodol 150 mg Injection 1 ml out of reach and sight of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Side effects of Zerodol 150 mg Injection 1 ml

Indigestion

Here are the step-by-step strategies to manage the side effects of "indigestion" caused by medication usage:

Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.

Stomach Pain

Drink water or other clear fluids.
To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
Include bland foods like rice, toast, crackers, and rice in your diet.
Avoid lying down immediately after eating as it may cause indigestion or heartburn.
Avoid acidic and spicy food as it may cause indigestion.

Nausea

Overcome Medication-Induced Nausea: A 9-Step Plan

Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
Divide your daily food intake into smaller, more frequent meals to reduce nausea.
Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
Use ginger (tea, ale, or candies) to help relieve nausea.
Get adequate rest and also avoid strenuous activities that can worsen nausea.
Talk to your doctor about taking anti-nausea medication if your nausea is severe.
Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.

Loose And Watery Stools

Here are the precise steps to cope with diarrhoea caused by medication usage:

Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.

Gas Or Fart

Here are the steps to manage Gastrointestinal Air and Swelling (GAS) caused by medication:

Tell your doctor about your GAS symptoms. They may change your medication regimen or prescribe additional drugs to help you manage them.
To manage GAS symptoms, eat a balanced diet of fibre, vegetables, and fruits.
Drink enough water throughout the day to avoid constipation and treat GAS symptoms.
Regular exercise like yoga and walking may help stimulate digestion and alleviate GAS symptoms.
Take probiotics only if your doctor advises, as they may help alleviate GAS symptoms by promoting gut health.
Take medication for GAS symptoms only if your doctor advises, as certain medications can interact with your existing prescriptions or worsen symptoms.
If symptoms persist, worsen, or are accompanied by severe abdominal pain, vomiting, or bleeding, seek immediate medical attention.

Dizziness

Here are the 7 steps to manage Dizziness caused by medication:

Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
When standing up, do so slowly and carefully to avoid sudden dizziness.
Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.

Dizziness Or Spinning Sensation

Here are the 7 steps to manage Dizziness caused by medication:

Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
When standing up, do so slowly and carefully to avoid sudden dizziness.
Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.

What if I have taken an overdose of Zerodol 150 mg Injection 1 ml

Zerodol 150 mg Injection 1 ml is administered by a health care professional in a hospital setting. Hence, the chances of overdose are less. Symptoms of overdose may include agitation, confusion, coma (decreased level of consciousness and lack of responsiveness), and Seizures, in a very severe overdose. Dizziness, drowsiness, blurred vision, and delirium are the common symptoms of overdose. Your doctor may take necessary measures if an overdose is suspected.

Drug Warnings

Do not take Zerodol 150 mg Injection 1 ml if you are allergic to any of its components; if you have peptic ulcers, intestinal bleeding problems, or severe kidney problems. Inform your doctor if you have/had blood circulation problems, asthma, porphyria (blood disorder), diabetes, high blood pressure, auto-immune diseases, or connective tissue diseases. Zerodol 150 mg Injection 1 ml may cause dizziness, so drive only if you are alert. Zerodol 150 mg Injection 1 ml is not recommended for use during pregnancy, lactation, and in children. Avoid consuming alcohol along with Zerodol 150 mg Injection 1 ml as it could lead to increased dizziness.

Drug-Drug Interactions

AceclofenacAtenolol

Severe

Drug-Drug Interactions

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AceclofenacAtenolol

Severe

How does the drug interact with Zerodol 150 mg Injection 1 ml:
Co-administration of Atenolol with Zerodol 150 mg Injection 1 ml could increase the risk of low blood pressure.

How to manage the interaction:
Although there is a possible interaction between Atenolol and Zerodol 150 mg Injection 1 ml, you can take these medicines together if prescribed by a doctor. Consult a doctor if you experience excessive sweating, shortness of breath, palpitations, or chest discomfort. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

Physical activity helps in strengthening muscles and relieves joint stiffness. Gentle activities like 20-30minutes of walking or swimming would be helpful.
Performing yoga may also help in improving joint flexibility and pain management.
Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
Get adequate sleep as resting the muscles can help in reducing inflammation and swelling.
Follow heat or cold therapy, apply a cold or hot compress on the joints for 15-20minutes regularly.
De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
Acupuncture, massage and physical therapy may also be helpful.
Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
Foods containing flavonoids help in reducing inflammation. These include soy, berries, broccoli, grapes and green tea.
Avoid smoking and alcohol consumption.

Habit Forming

No

Therapeutic Class

ANALGESICS

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Alcohol

Unsafe

Avoid consumption of alcohol while taking Zerodol 150 mg Injection 1 ml as it may cause increased dizziness.

Pregnancy

Unsafe

Zerodol 150 mg Injection 1 ml is not recommended for use during pregnancy. Consult your doctor if you are pregnant or planning for pregnancy.

Breast Feeding

Unsafe

It is not known if Zerodol 150 mg Injection 1 ml passes into breastmilk. Zerodol 150 mg Injection 1 ml is not recommended for use in lactating mothers.

Driving

Caution

Zerodol 150 mg Injection 1 ml may cause dizziness. Drive only if you are alert.

Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

Kidney

Caution

Zerodol 150 mg Injection 1 ml is not recommended for people with severe renal impairment. Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

Children

Unsafe

Zerodol 150 mg Injection 1 ml is not recommended for children as the safety and effectiveness were not established.

Heart

Please let your doctor know if you have any history of heart problems before receiving Zerodol 150 mg Injection 1 ml.

Geriatrics

Caution

Zerodol 150 mg Injection 1 ml should be used with caution in elderly patients. Please consult your doctor before use.

FAQs

What is the use of Zerodol 150 mg Injection 1 ml?

Zerodol 150 mg Injection 1 ml belongs to a group of medicines called Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) or pain killers used to reduce and relieve pain, and inflammation (swelling) associated with osteoarthritis, rheumatoid arthritis and ankylosing spondylitis, pain associated with post-traumatic and post-operative cases.

Does Zerodol 150 mg Injection 1 ml cause diarrhoea?

Zerodol 150 mg Injection 1 ml works by blocking the effect of chemical messengers that causes pain and swelling. This helps in reducing mild to moderate pain and inflammation at the injured or damaged site.

Does Zerodol 150 mg Injection 1 ml cause nausea and vomiting?

Diarrhoea might be a side-effect of Zerodol 150 mg Injection 1 ml. Drink enough fluids and eat non-spicy food if you experience diarrhoea. If you find blood in stools (tarry stools) or if you have severe diarrhoea consult your doctor. Do not take anti-diarrheal medicine on your own.

I have peptic ulcers. Can I take Zerodol 150 mg Injection 1 ml?

Zerodol 150 mg Injection 1 ml may cause nausea and vomiting. It is not necessary for everyone taking Zerodol 150 mg Injection 1 ml to experience these side effects. However, if the condition persists or worsens, consult your doctor.

Country of origin

India

Manufacturer/Marketer address

142 AB, Kandivli Industrial Estate, Kandivli (West), Mumbai - 400 067, Maharashtra

Other Info - ZER0033

Author Details

Written By

Santoshini Reddy G

M Pharmacy

Reviewed By

Veda Maddala

M Pharmacy

Last Updated

Oct 14, 2025 | 1:09 PM IST

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