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compositionComposition:CEFUROXIME-125MG+CLAVULANIC ACID-31.25MG
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Prescription Medicine
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Zefu CV Syrup is used to treat various bacterial infections such as pharyngitis/tonsillitis (throat infections), otitis media (ear infections), sinusitis (infection of the sinuses), gonorrhoea (sexually transmitted disease), Lyme disease, septicaemia (bloodstream infection), meningitis (inflammation of the brain and spinal cord), lower respiratory tract, skin, urinary tract, bone, and joint infections. It contains Cefuroxime and Clavulanic acid, which work by preventing the formation of bacterial cell covering, which is necessary for their survival. Thus, it kills the bacteria. Also, it decreases bacterial resistance and enhances the activity of cefuroxime against the bacteria. In some cases, it may cause certain common side effects, such as diarrhoea, abdominal pain, nausea, and vomiting.

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Written By Dr. Suraj Pandey , BDS
Reviewed By Dr. E Naresh Kumar , MD, MBBS
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More about the Product

Composition :

CEFUROXIME-125MG+CLAVULANIC ACID-31.25MG

Manufacturer/Marketer :

FDC Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

NPPA :

Regulated

About Zefu CV Syrup

Zefu CV Syrup is a prescription medicine used to treat a wide variety of bacterial infections in the body. It belongs to the class of drugs known as antibiotics and is commonly prescribed to treat infections of the lungs, ears, nose, throat, urinary tract, and skin. By targeting and eliminating the bacteria responsible for these illnesses, it helps your body recover from the infection.

To achieve the best results, you must take Zefu CV Syrup regularly and at consistently spaced intervals exactly as directed by your healthcare provider. It is highly recommended to take this medicine with food, which helps your body absorb the active ingredients better and significantly reduces the risk of stomach upset. Getting plenty of rest and staying well-hydrated during your recovery can also help speed up your healing process.

While taking Zefu CV Syrup, you may experience mild and temporary side effects such as nausea, diarrhoea, or mild stomach discomfort. However, if you develop severe or persistent watery diarrhoea, a high fever, or severe abdominal pain, you should stop taking the medicine and consult your doctor immediately. These symptoms can be signs of a more serious intestinal condition that requires prompt professional attention.

Talk to your doctor before starting Zefu CV Syrup if you have a history of kidney disease, liver problems, or severe digestive issues such as colitis. Do not take this medicine if you have ever had a severe allergic reaction, such as a severe skin rash, hives, or breathing difficulties, when taking penicillin or other related antibiotics.

This medicine may interact with other treatments, including blood thinners, certain gout medications, or antacids, which can alter how well the treatment works in your body. It is also important to consult your healthcare provider if you are pregnant, planning to become pregnant, breastfeeding, or managing health conditions in elderly individuals before starting this medication.

Uses of Zefu CV Syrup

Zefu CV Syrup may be prescribed for the following bacterial infections: 

  • Respiratory tract infections: Zefu CV Syrup helps clear bacterial infections in the lungs and airways, such as bronchitis and pneumonia, allowing you to breathe more easily.
  • Ear, nose, and throat infections: It effectively treats painful infections such as middle ear infections, severe sinusitis, and tonsillitis by destroying the causative bacteria.
  • Urinary tract infections: This medication targets and eliminates bacteria in the bladder and kidneys, relieving painful urination and lower abdominal discomfort.
  • Skin and soft tissue infections: It helps cure bacterial skin infections, such as cellulitis or infected wounds, preventing the spread of the infection and promoting faster healing.
     

Key Benefits

Taking Zefu CV Syrup offers several clinical benefits that help you feel better and recover safely from a bacterial infection.

  • Dual-action defence: The medicine combines two active components to overcome bacterial resistance, making it highly effective even against stubborn bacterial strains.
  • Rapid symptom relief: By quickly stopping bacterial growth, it helps reduce fever, pain, and inflammation within a few days of starting treatment.
  • Prevents infection spread: It thoroughly clears the bacteria from your system, reducing the risk of the infection spreading to other parts of your body or returning after treatment.
     
Side effects of Zefu CV Syrup 30 ml
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • Get plenty of fresh air.
  • Take regular sips of a cold drink.
  • Take ginger containing foods like ginger tea and ginger biscuits.
  • Do not take heavy meals at a time, take small and frequent meals.
  • Drink small sips of liquids frequently, especially water or oral rehydration solutions, to prevent dehydration, even if vomiting occurs.
  • Monitor urine output; frequent, light-colored urine is a sign of proper hydration.
  • Eat bland, easily digestible foods like toast, plain rice, applesauce, bananas, and crackers.
  • Avoid spicy, fatty, or greasy foods, dairy products, alcohol, and caffeine as these can irritate the stomach.
  • Eat smaller meals more often instead of large ones.
  • Get enough rest to allow your body to recover.
  • If you experience severe vomiting, bloody stools, diarrhea, high fever, significant dehydration, or signs of electrolyte imbalance, consult your doctor.
  • Focus on eating nutrient-rich foods such as citrus fruits, spinach, ginger, garlic, turmeric, and fermented foods to improve immunity and general health.
  • Drink plenty of water to stay hydrated, and think about taking probiotics, zinc, vitamin C, and vitamin D supplements.
  • Adopt healthful practices such as leading a balanced lifestyle and remaining at home when necessary.
Here are the steps to manage the medication-triggered Upper respiratory tract infection:
  • Inform your doctor about the symptoms you're experiencing due to medication.
  • Your doctor may adjust your treatment plan, which could include changing your medication, adding new medications, or offering advice on managing your symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Stay hydrated by drinking plenty of fluids to help loosen and clear mucus from your nose, throat, and airways.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your symptoms don't subside or worsen, consult your doctor for further guidance.
Here are the steps to manage the medication-triggered Sinusitis (Sinus infection or Inflammation Of Sinuses):
  • Consult your doctor if you experience symptoms of sinusitis, such as nasal congestion, facial pain, or headaches, which may be triggered by your medication.
  • Your doctor may adjust your treatment plan by changing your medication, adding new medications, or providing guidance on managing your sinusitis symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • If your doctor advises, you can use nasal decongestants or saline nasal sprays to help relieve nasal congestion and sinus pressure.
  • To help your body recover, get plenty of rest, stay hydrated, and engage in stress-reducing activities. If your symptoms persist or worsen, consult your doctor for further guidance.

Directions for Use

Follow these instructions to ensure you take this medication safely and effectively:

  • Take this medicine by mouth, exactly as prescribed by your doctor.
  • Swallow the tablet whole with a full glass of water. Do not crush, chew, or break the tablet, as this can affect how the medicine is released in your body.
  • Always take this medication with a meal to improve its absorption into your bloodstream and to help prevent stomach irritation.
  • Complete the full course of treatment even if you start feeling better after a few days. Stopping the medicine too early can allow the remaining bacteria to multiply and return.

Always follow your doctor's exact instructions regarding your specific schedule and treatment length.
 

How Zefu CV Syrup Works

Taking Zefu CV Syrup offers several clinical benefits that help you feel better and recover safely from a bacterial infection. Dual-action defence: The medicine combines two active components to overcome bacterial resistance, making it highly effective even against stubborn bacterial strains. Rapid symptom relief: By quickly stopping bacterial growth, it helps reduce fever, pain, and inflammation within a few days of starting treatment. Prevents infection spread: It thoroughly clears the bacteria from your system, reducing the risk of the infection spreading to other parts of your body or returning after treatment.
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Alcohol

Unsafe

Avoid consuming alcohol while taking Zefu CV Syrup to prevent unpleasant side effects.

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Pregnancy

Consult your doctor

Zefu CV Syrup belongs to pregnancy category B. Please consult your doctor if you are pregnant; your doctor will prescribe Zefu CV Syrup only if the benefits outweigh the risks.

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Breast Feeding

Unsafe

Zefu CV Syrup contains cefuroxime, which passes into breast milk. Avoid taking Zefu CV Syrup if you are breastfeeding.

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Driving

Safe if prescribed

Zefu CV Syrup does not affect your ability to drive. However, you are advised not to drive or operate machinery if you feel unwell.

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Liver

Consult your doctor

Please consult your doctor before taking Zefu CV Syrup if you have liver impairment/liver disease.

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Kidney

Consult your doctor

Please consult your doctor if you have any concerns regarding this or if you have kidney impairment/kidney disease before taking Zefu CV Syrup.

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Children

Safe if prescribed

Zefu CV Syrup is safe for children if prescribed by a doctor. The dose and duration may vary depending on age and severity of the infection.

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Heart

Consult your doctor

Please consult your doctor before using Zefu CV Syrup if you have pre-existing heart problems. Your doctor will prescribe Zefu CV Syrup if the benefits outweigh the risks.

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Geriatrics

Consult your doctor

Please consult a doctor before administering Zefu CV Syrup to geriatric patients. Your doctor will prescribe Zefu CV Syrup if the benefits outweigh the risks.

What if I have taken an overdose of Zefu CV Syrup

Please do not take more than the prescribed dose of Zefu CV Syrup as it may cause overdose, resulting in cerebral irritation leading to convulsions (fits). If you suspect you have takenan overdose or notice signs of overdose, please consult a doctor immediately.

Diet & Lifestyle Advise

  • Take with meals: Always plan your doses around your breakfast, lunch, or dinner. Taking this medication with food significantly increases its absorption and reduces gastrointestinal discomfort.
  • Stay well-hydrated: Drink plenty of water throughout the day. Staying hydrated helps your kidneys process and clear the medication from your body efficiently.
  • Support your gut health: Antibiotics can disrupt the natural balance of bacteria in your digestive system.Consider eating yoghurt or taking probiotic supplements, but make sure to consume them at least two hours before or after taking your antibiotic dose to prevent them from interfering with each other.
  • Avoid alcohol: Refrain from drinking alcohol while on this medication, as it can worsen common side effects like dizziness and stomach upset, and slow down your body's natural recovery.
     
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Have a query?

How Soon It Starts Working

  • The time required for Zefu CV Syrup to start to work: Zefu CV Syrup ideally shows its action within 2 to 3 hours after administration.
  • The time for which the effects of Zefu CV Syrup last: The effect of Zefu CV Syrup lasts for 4 to 8 hours.

What if you forget to take Zefu CV Syrup

If you miss a dose of Zefu CV Syrup, take it as soon as you remember. However, if it is almost time for the next dose, skip the missed one and continue with your regular schedule. Do not take a double dose to make up for the missed one.

Storage

• Store the tablets in their original packaging at room temperature, strictly below 30°C (86°F). •Keep the medicine in a dry place away from direct sunlight, moisture, and heat.

Drug Warnings

  • Finish the entire bottle: Even if your symptoms clear up completely after a few days, finish the full course of treatment to prevent the bacteria from returning and developing resistance.
  • Watch for yeast infections: Because this medicine eliminates both good and bad bacteria, it can lead to overgrowth of yeast, resulting in oral thrush or vaginal yeast infections. Contact your doctor if you notice unusual white patches in your mouth or vaginal itching and discharge.
  • Oral contraceptives: Current evidence suggests that most antibiotics, including cefuroxime-containing antibiotics, do not significantly reduce the effectiveness of hormonal contraceptives. However, if you experience severe vomiting or diarrhoea, contraceptive absorption may be affected. Discuss any concerns with your doctor and follow personalised advice if additional contraception is recommended.
  • Never share your medicine: This antibiotic is prescribed specifically for your current infection. Sharing it with others or using it for a different infection in the future can be dangerous and ineffective.
  • Avoid antacids: Antacids containing magnesium or aluminium may reduce the absorption of the cefuroxime component. As a precaution, your doctor or pharmacist may advise separating the doses. If you regularly use antacids, consult your pharmacist for individual guidance.
     

Drug-Drug Interactions

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Drug-Drug Interactions

Inform your doctor if you are taking any of the following medicines, as they may interact with Zefu CV Syrup: 

  • Antacids: Medications containing aluminium or magnesium may reduce the absorption of the cefuroxime component. This interaction is usually minor and can often be managed by separating the doses. Consult your doctor or pharmacist if you regularly use antacids.
  • Blood thinners: Taking this medicine alongside blood thinners like warfarin may increase your risk of bleeding. Your doctor may need to monitor your blood clotting levels more closely.
  • Gout medications: Medicines like probenecid can slow down the removal of this antibiotic by your kidneys, leading to higher levels of the drug in your bloodstream and an increased risk of side effects.
  • Oral contraceptives: Severe vomiting or diarrhoea caused by illness or treatment may affect contraceptive absorption. Consult your doctor if you have concerns about contraceptive protection during treatment.

Drug-Food Interactions

  • Meals: Taking this medicine on an empty stomach can lower its absorption rate and reduce its clinical efficacy. Always take it with food.

Drug-Disease Interactions

Inform your doctor if you have any of the following conditions before taking Zefu CV Syrup: 

  • Kidney disease: If you have severe kidney impairment, your kidneys may clear this medicine more slowly. Your doctor may need to adjust your dose to prevent side effects.
  • Colitis or digestive disorders: If you have a history of severe bowel inflammation (colitis), taking this medicine can trigger severe diarrhoea or worsen your condition.
  • Penicillin allergy: If you have a history of severe allergic reactions to penicillin antibiotics, inform your doctor before starting treatment. Although cross-reactivity between penicillins and cephalosporins such as cefuroxime is relatively uncommon, it can occur, particularly in people who have experienced severe allergic reactions such as anaphylaxis.
     
Cefuroxime + Clavulanic acidMycophenolic acid
Severe
Cefuroxime + Clavulanic acidBCG vaccine
Severe

Drug-Drug Interactions

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Cefuroxime + Clavulanic acidMycophenolic acid
Severe
How does the drug interact with Zefu CV Syrup 30 ml:
Taking mycophenolic acid and cefuroxime together can reduce the blood levels and effects of mycophenolic acid.

How to manage the interaction:
Using mycophenolic acid and cefuroxime together can lead to an interaction; it can be taken if your doctor has suggested it. If you experience any symptoms, like less urine output, shortness of breath, or swelling, contact the doctor immediately. Do not discontinue any medications without consulting your doctor.
Cefuroxime + Clavulanic acidBCG vaccine
Severe
How does the drug interact with Zefu CV Syrup 30 ml:
Co-administration of Cefuroxime may reduce the anti-tumor activity of BCG in the bladder.

How to manage the interaction:
Talk to your doctor before receiving BCG if you are currently being treated with cefuroxime. To ensure adequate response to your treatment, you should not receive BCG until after you complete your antibiotic therapy. Do not discontinue the medication without consulting a doctor.
Cefuroxime + Clavulanic acidCholera, live attenuated
Severe
How does the drug interact with Zefu CV Syrup 30 ml:
Taking the cholera vaccine after or along with cefuroxime may reduce the activity of the vaccine.

How to manage the interaction:
Although taking cefuroxime and cholera attenuated together can evidently cause an interaction, it can be taken if your doctor has suggested it. To ensure an adequate vaccine response, you should not receive the cholera vaccine and live until at least 14 days after you complete your antibiotic therapy. If you experience any unusual side effects, consult a doctor. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTIBIOTICS]

FAQs

Zefu CV Syrup is used to treat various bacterial infections such as pharyngitis/tonsillitis (throat infections), otitis media (ear infections), sinusitis (infection of the sinuses), gonorrhoea (sexually transmitted disease), Lyme disease, septicaemia (bloodstream infection), meningitis (inflammation of the brain and spinal cord), lower respiratory tract, skin, urinary tract, bone, and joint infections.
Zefu CV Syrup is a combination of two antibiotics, namely: Cefuroxime (cephalosporin antibiotic) and Clavulanic acid (beta-lactamase inhibitor). Cefuroxime works by preventing the formation of the bacterial cell covering, which is necessary for their survival. Thereby, kills the bacteria. Clavulanic acid works by decreasing bacterial resistance and enhancing the activity of cefuroxime against the bacteria. Together, Zefu CV Syrup helps to treat bacterial infections.
Yes, diarrhoea can occur while taking Zefu CV Syrup. Drink plenty of fluids and eat a balanced diet to stay hydrated. However, if you develop severe, persistent, watery, or bloody diarrhoea, especially with abdominal cramps or fever, stop taking the medicine and contact your doctor immediately. Do not take anti-diarrhoeal medicines without medical advice.
No. Do not stop taking Zefu CV Syrup without consulting your doctor, even if your symptoms improve. Stopping the antibiotic too early may allow some bacteria to survive, causing the infection to return and increasing the risk of antibiotic resistance. Complete the full course prescribed by your doctor.
Do not take Zefu CV Syrup on your own, as self-medication can lead to antibiotic resistance, where antibiotics fail to act against specific bacterial infections.
Avoid taking antacid medicines along with Zefu CV Syrup as reduced gastric acidity might lower the effectiveness of Zefu CV Syrup.
Current evidence suggests that cefuroxime-containing antibiotics do not significantly reduce the effectiveness of hormonal contraceptives. However, severe vomiting or diarrhoea may affect the absorption of oral contraceptive pills and reduce their effectiveness. If this occurs, follow the instructions provided with your contraceptive and consult your doctor for advice.
The dose and duration of Zefu CV Syrup can vary depending on your condition and the severity of the infection.
Yes, it can be used to treat urinary tract infections (UTIS). However, it should only be taken if recommended by a healthcare professional.
Zefu CV Syrup is a combination of two antibiotics: Cefuroxime (cephalosporin antibiotic) and Clavulanic acid (beta-lactamase inhibitor).
It is recommended to avoid alcohol while taking Zefu CV Syrup. Alcohol may increase side effects such as stomach upset, dizziness, and dehydration, which can slow recovery from infection.
Common side effects of Zefu CV Syrup may include diarrhoea, abdominal pain, nausea, and vomiting. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
No, it is highly recommended to take Zefu CV Syrup with food. Taking it with a meal improves the absorption of the medicine into your body and helps prevent common side effects like stomach upset. Talk to your doctor or pharmacist if you have trouble taking it with meals.
This medicine should only be used during pregnancy or breastfeeding when clearly needed and prescribed by a doctor. Although it is generally considered safe, you should always discuss the potential risks and benefits with your doctor before starting treatment.
No, Zefu CV Syrup is an antibiotic and is only effective against bacterial infections. It will not work for viral infections such as the common cold, flu, or most sore throats. Using antibiotics unnecessarily can make them less effective for future bacterial infections. Talk to your doctor for an accurate diagnosis.
Take the missed dose as soon as you remember. If it is almost time for your next scheduled dose, skip the missed dose and resume your regular dosing schedule. Do not take a double dose to make up for a missed one. Talk to your doctor or pharmacist if you miss multiple doses.
Many people begin to notice improvement within 2 to 3 days of starting treatment. However, if your symptoms do not improve, worsen, or new symptoms develop despite taking the medicine as prescribed, contact your doctor. Your infection may require further evaluation, additional testing, or a different treatment approach.

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While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

FDC LIMITED, B-8, MIDC Area, Waluj - 431 136, Dist. Aurangabad, Maharashtra.
Other Info - ZEF0028
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