apollo
0

Welcome User

Login/Sign Up

Home
Buy Medicines
Lab Tests
Doctor Consult
Circle Membership
insurance
Blogs
Contact Us
Privacy Policy
Return & Refunds
Need Help
Terms and Conditions
  1. Home
  2. Medicine

  3. Zam-MT 0.25 Tablet 10's

Not for online sale
Zam-MT 0.25 Tablet 10's, Pack of 10
Offers on medicine orders
All offers
axis icici
Written By Lakshmithulasi Yarragunta ,
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Zam-MT 0.25 Tablet 10's is used to treat sleeplessness (insomnia). Besides this, it also helps to provide a calming effect on anxiety disorder and panic disorder. It contains Alprazolam and Melatonin, which reduces the abnormal and overactivity of brain cells (neurons), which in turn relaxes the brain and promotes sleep. Melatonin is a natural hormone that activates the ON-OFF mechanism of a person's sleeping-waking cycle (circadian cycle), thereby inducing sleep during the night time. It may cause common side effects such as drowsiness, tiredness, headache, depressed mood, daytime drowsiness, stomach pain, and dizziness. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
Read more

Composition :

ALPRAZOLAM-0.25MG + MELATONIN-3MG

Manufacturer/Marketer :

East West Pharma India Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

About Zam-MT 0.25 Tablet 10's

Zam-MT 0.25 Tablet 10's is used to treat sleeplessness (insomnia). Besides this, it also helps to provide a calming effect on anxiety disorder and panic disorder. Insomnia is a sleeping disorder in which a person finds difficulty falling asleep or staying asleep. Due to anxiety and panic disorder, a person cannot sleep due to disturbances in their circadian cycle and hormonal imbalances in the brain, like melatonin. 

Zam-MT 0.25 Tablet 10's is a combination of two medicines, Alprazolam and Melatonin, which help a person fall asleep faster and stay asleep during the night. Alprazolam is a benzodiazepine (BZD) that increases the activity of a chemical messenger in the brain known as GABA, reducing the abnormal and overactivity of brain cells (neurons), which in turn relaxes the brain and promotes sleep. On the other hand, Melatonin is a natural hormone that activates the ON-OFF mechanism of a person's sleeping-waking cycle (circadian cycle), thereby inducing sleep during the nighttime. 

Take Zam-MT 0.25 Tablet 10's with or without food and swallow whole with a glass of water. Do not break, crush, or chew it. Your doctor will advise you how often you take Zam-MT 0.25 Tablet 10's based on your medical condition. The most common side effects of Zam-MT 0.25 Tablet 10's include drowsiness, tiredness, headache, depressed mood, daytime drowsiness, stomach pain, and dizziness. Most of these side effects of Zam-MT 0.25 Tablet 10's do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Tell your doctor if you have an ongoing medical condition, including depression, diabetes, an autoimmune disorder, or high blood pressure. If you are known to be allergic to Zam-MT 0.25 Tablet 10's or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, inform your doctor before taking Zam-MT 0.25 Tablet 10's. Zam-MT 0.25 Tablet 10's should be used with caution in elderly patients as there is an increased risk of adverse reactions such as dizziness, muscle weakness, and drowsiness.

Uses of Zam-MT 0.25 Tablet 10's

Zam-MT 0.25 Tablet 10's is used in the treatment of Insomnia (sleeplessness). The detailed uses of Zam-MT 0.25 Tablet 10's are as follows:<br/>• Sleep Enhancement: Zam-MT 0.25 Tablet 10's is used to treat sleeplessness (insomnia), promoting a restful night's sleep and helping to regulate sleep patterns.<br/>• Anxiety and Calming Effects: Zam-MT 0.25 Tablet 10's provides a calming effect on anxiety disorders and panic disorders, helping individuals manage stress and achieve improved mental well-being.<br/>

Have a query?

Directions for Use

• Zam-MT 0.25 Tablet 10's can be taken with or without food as advised by your doctor.• Follow your doctor's instructions on the dosage and timing of this medication.• Swallow Zam-MT 0.25 Tablet 10's as a whole with a glass of water.• Do not crush, break, or chew it.

Medicinal Benefits

Zam-MT 0.25 Tablet 10's belongs to a class of sedatives and hypnotics, primarily used to treat insomnia (difficulty in falling asleep or staying asleep). Zam-MT 0.25 Tablet 10's is a combination of two medicines: 'Alprazolam' and  'Melatonin', which helps a person fall asleep faster and stay asleep during the night, which has been disturbed due to anxiety or panic disorder. Zam-MT 0.25 Tablet 10's helps relax the brain's exciting chemicals (GABA), allowing a person to sleep easily and stay asleep during the whole night without any disturbance.  

How Zam-MT 0.25 Tablet 10's Works

Zam-MT 0.25 Tablet 10's is a combination of two medicines, Alprazolam and Melatonin, which help a person fall asleep faster and stay asleep during the night. Alprazolam is a benzodiazepine (BZD) that increases the activity of a chemical messenger in the brain known as GABA, reducing the abnormal and overactivity of brain cells (neurons), which in turn relaxes the brain and promotes sleep. On the other hand, Melatonin is a natural hormone that activates the ON-OFF mechanism of a person's sleeping-waking cycle (circadian cycle), thereby inducing sleep during the nighttime.

Storage

Keep Zam-MT 0.25 Tablet 10's out of the sight and reach of children.
Side effects of Zam-MT 0.25 Tablet
  • Get enough sleep. Maintain a regular sleep cycle.
  • Eat a healthy diet and exercise regularly.
  • Manage stress with yoga or meditation.
  • Limit alcohol and caffeine.
  • Avoid driving or operating machinery unless you are alert.
  • Restlessness is related to mental health and needs medical attention if it's severe.
  • Regular practice of meditation and yoga can help calm your mind. This can reduce restlessness.
  • Prevent smoking as it can impact your calmness of body and mind.
  • Talk to your friends and family about restlessness, who can provide a solution for why you feel restless.
  • Get sufficient sleep for a minimum of 6-7 hours to reduce restlessness.
  • Manage stress by practising deep breathing, yoga or meditation.
  • Get enough sleep. Maintain a regular sleep cycle.
  • Exercise regularly. Try physical activities like walking, running, or dancing.
  • Limit stimulants like tea, coffee and alcohol.
  • Identify triggers and try managing them.
  • Take a break by scheduling time for yourself.
  • Try creative activities like writing, dancing or painting as it helps release tension.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.

What if I have taken an overdose of Zam-MT 0.25 Tablet 10's

Do not take more than the prescribed dose of Zam-MT 0.25 Tablet 10's as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

Before your doctor prescribes your Zam-MT 0.25 Tablet 10's, you should tell your doctor if you have allergies or not. With it, also tell if you are pregnant or breastfeeding as the use of this medication is restricted to be used in pregnancy and breastfeeding. Elderly people are more responsive to the side effects of the drug, so they should tell every product, including the herbal ones to their doctor so that doctor can decide the dosage for them. Inform your doctor about myasthenia gravis (muscle weakness), drug addiction, chronic pulmonary insufficiency, narrow-angle glaucoma, and kidney/liver problem before taking Zam-MT 0.25 Tablet 10's. Do not take Zam-MT 0.25 Tablet 10's with opioids as it may cause breathing problems, drowsiness and coma.

Drug-Drug Interactions

verifiedApollotooltip
AlprazolamCeritinib
Critical
AlprazolamSodium oxybate
Critical

Drug-Drug Interactions

Login/Sign Up

AlprazolamCeritinib
Critical
How does the drug interact with Zam-MT 0.25 Tablet:
Co-administration of Zam-MT 0.25 Tablet with Ceritinib may considerably increase the blood levels and effects of Zam-MT 0.25 Tablet.

How to manage the interaction:
Although there is a interaction between Zam-MT 0.25 Tablet and Ceritinib, it can be taken if prescribed by a doctor. Consult a doctor if you experience excessive or prolonged drowsiness or difficulty in breathing. Do not discontinue any medications without consulting a doctor.
AlprazolamSodium oxybate
Critical
How does the drug interact with Zam-MT 0.25 Tablet:
Co-administration of Zam-MT 0.25 Tablet with Sodium Oxybate may increase Sodium Oxybate's adverse effects (respiratory depression, low blood pressure, fainting).

How to manage the interaction:
Although the combination of Zam-MT 0.25 Tablet and sodium oxybate may cause an interaction, they can be used if prescribed by a doctor. Consult a doctor if you suffer any of the following symptoms: breathing difficulties, low blood pressure, being severely drowsy, or fainting. Avoid driving or operating hazardous machinery or performing other hazardous activities for at least 6 hours after taking a dose. Do not discontinue any medications without consulting a doctor.
AlprazolamDelavirdine
Critical
How does the drug interact with Zam-MT 0.25 Tablet:
The combination of Zam-MT 0.25 Tablet and Delavirdine may considerably increase the risk of side effects.

How to manage the interaction:
Despite the fact that there is an interaction between Zam-MT 0.25 Tablet and Delavirdine, it can be used if prescribed by a doctor. Consult a doctor if you have sleepiness, dizziness, confusion, or weak or rapid breathing over a long duration of time. Do not discontinue any medications without consulting a doctor.
AlprazolamClarithromycin
Critical
How does the drug interact with Zam-MT 0.25 Tablet:
The combination of Zam-MT 0.25 Tablet and clarithromycin may considerably increase the risk of side effects.

How to manage the interaction:
Despite the fact that there is an interaction between Zam-MT 0.25 Tablet and clarithromycin, it can be used if prescribed by a doctor. Consult a doctor if you have excessive drowsiness, problems with movement, memory loss, anxiety, hallucinations (illogical thoughts), or breathing issues (particularly if you have asthma or obstructive sleep apnea). Do not discontinue any medications without consulting a doctor.
AlprazolamItraconazole
Critical
How does the drug interact with Zam-MT 0.25 Tablet:
Zam-MT 0.25 Tablet's blood levels may be significantly raised when combined with itraconazole.

How to manage the interaction:
Although combining Zam-MT 0.25 Tablet and Itraconazole may lead to an interaction, they can be taken if prescribed by a doctor. Consult a doctor if you get extremely drowsy and your breathing becomes slow. Without consulting a doctor, never stop taking any medication.
AlprazolamIndinavir
Critical
How does the drug interact with Zam-MT 0.25 Tablet:
The combination of Zam-MT 0.25 Tablet and Indinavir may considerably increase the risk of side effects.

How to manage the interaction:
Despite the fact that there is an interaction between Zam-MT 0.25 Tablet and Indinavir, it can be used if prescribed by a doctor. Consult a doctor if you have drowsiness, lightheadedness, palpitations, confusion, severe weakness, or difficulty breathing. Do not discontinue any medications without consulting a doctor.
AlprazolamKetoconazole
Critical
How does the drug interact with Zam-MT 0.25 Tablet:
Co-administration of Zam-MT 0.25 Tablet with Ketoconazole may considerably increase the blood levels of Zam-MT 0.25 Tablet, which may result in side effects.

How to manage the interaction:
Although there is an interaction between Zam-MT 0.25 Tablet and Ketoconazole, it can be taken if prescribed by a doctor. Consult a doctor if you experience excessive or prolonged drowsiness or difficulty in breathing. Do not discontinue any medications without consulting a doctor.
AlprazolamCobicistat
Critical
How does the drug interact with Zam-MT 0.25 Tablet:
Co-administration of Zam-MT 0.25 Tablet with Cobicistat may considerably increase the blood levels and effects of Zam-MT 0.25 Tablet.

How to manage the interaction:
Despite the fact that there is an interaction between Zam-MT 0.25 Tablet and Cobicistat, it can be taken if prescribed by a doctor. Consult a doctor if you experience excessive or prolonged drowsiness or difficulty in breathing. Do not discontinue any medications without consulting a doctor.
AlprazolamSaquinavir
Severe
How does the drug interact with Zam-MT 0.25 Tablet:
Co-administration of Zam-MT 0.25 Tablet with Saquinavir may considerably increase the blood levels and effects of Zam-MT 0.25 Tablet.

How to manage the interaction:
Despite the fact that there is an interaction between Zam-MT 0.25 Tablet and Saquinavir, it can be taken if prescribed by a doctor. Consult a doctor if you experience excessive or prolonged drowsiness or difficulty in breathing. Do not discontinue any medications without consulting a doctor.
AlprazolamConivaptan
Severe
How does the drug interact with Zam-MT 0.25 Tablet:
Co-administration of Zam-MT 0.25 Tablet and Conivaptan may considerably enhance blood levels and side effects of Conivaptan.

How to manage the interaction:
Although the combination of Zam-MT 0.25 Tablet and Conivaptan may cause an interaction, they can be used if prescribed by a doctor. Consult a doctor if you suffer any of the following symptoms: trouble swallowing, trouble speaking, muscle weakness, difficulty controlling body movements, confusion, mood changes, fits, or unconsciousness. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

Login/Sign Up

Diet & Lifestyle Advise

  • Keeping a fixed time to go to bed and wake up consistently every day helps maintain a better sleeping and waking plan.

  • Engage yourself in workouts, dancing, and walking that help promote calmness in the body so that you can enjoy a good night's sleep.

  • Taking naps in a day can make it harder to fall asleep at night, so one should try to limit a nap to no more than half an hour and don't nap after 2 p.m. 

  • Limit caffeine and alcohol consumption as it will not let you sleep and causes frequent urination.

  • Avoid large, heavy meals before bed. One can have a light snack that helps to avoid heartburn.

  • Avoid consumption of alcohol as it may increase drowsiness.

  • Take less liquid before bedtime so that you won't have to urinate as often. One must keep their worries and planning aside and enjoy a warm bath or a massage before bedtime. It will help in having a good night's relaxing sleep.

Habit Forming

Yes

Therapeutic Class

SEDATIVE-HYPNOTIC DRUGS

Zam-MT 0.25 Tablet 10's Substitute

Substitutes safety advice
bannner image

Alcohol

Unsafe

Alcohol is sedative in nature, so taking it with Zam-MT 0.25 Tablet 10's may interrupt the sleep cycle. Alcohol may worsen the effects of Zam-MT 0.25 Tablet 10's so one should not consume it with Zam-MT 0.25 Tablet 10's.

bannner image

Pregnancy

Unsafe

Zam-MT 0.25 Tablet 10's is a category D pregnancy drug. It is not recommended for use during pregnancy, especially in the second and third trimesters as it may cause harm to the unborn baby.

bannner image

Breast Feeding

Unsafe

Avoid breastfeeding while taking Zam-MT 0.25 Tablet 10's as it may be excreted in breast milk and cause adverse effects in the baby.

bannner image

Driving

Unsafe

Zam-MT 0.25 Tablet 10's may cause dizziness, double vision, or drowsiness in some people. It is an offence to drive if Zam-MT 0.25 Tablet 10's affects you. Therefore, avoid driving if you feel drowsy, dizzy, or experience any vision problems after taking Zam-MT 0.25 Tablet 10's.

bannner image

Liver

Caution

Take Zam-MT 0.25 Tablet 10's with caution, especially if you have or had a history of liver diseases/conditions. The dose may be adjusted by your doctor as required.

bannner image

Kidney

Caution

Take Zam-MT 0.25 Tablet 10's with caution, especially if you have or had a history of kidney diseases/conditions. The dose may be adjusted by your doctor as required.

bannner image

Children

Caution

Not enough scientific data available for Zam-MT 0.25 Tablet 10's, hence it is best to consult a child specialist.

FAQs

Zam-MT 0.25 Tablet 10's belongs to a class of medication called sedatives and hypnotics, primarily used to treat sleeplessness (insomnia). Besides this, it also helps to provide a calming effect on anxiety disorder and panic disorder.

Zam-MT 0.25 Tablet 10's is a combination of two medicines: Alprazolam and Melatonin, which helps a person fall asleep faster and stay asleep during the night. Alprazolam is a benzodiazepine (BZD) that increases the activity of a chemical messenger in the brain known as GABA, reducing the abnormal and overactivity of brain cells (neurons), which in turn relaxes the brain and promotes sleep. On the other hand, Melatonin is a natural hormone that activates the ON-OFF mechanism of a person&amp;#039;s sleeping-waking cycle (circadian cycle), thereby inducing sleep during the nighttime.

It is advised not to take Zam-MT 0.25 Tablet 10's if you have a bleeding disorder as taking this medicine may worsen the medical condition. The use of Zam-MT 0.25 Tablet 10's is restricted in patients dealing with diabetes and depression.

It is advised not to stop taking this medicine by yourself. If you are noticing an improvement in their condition, then you should first consult with their doctor. The doctor will gradually reduce the dose and then stop it to avoid withdrawal effects

It is suggested not to indulge in any heavy exercise like running or put up heavyweights as it can make you active and wake for a long time. However, you can practice some mindful activities like meditation to make yourself relax and sleep properly. Doing heavy workouts before bed increases blood circulation and body temperature of the body and creates difficulty sleeping. Your bedroom should be dark and should be mend for only sleep.

It has been reported in some patients that Zam-MT 0.25 Tablet 10's may cause drowsiness. Therefore, it is recommended to avoid driving or any other activities that require mental alertness after taking Zam-MT 0.25 Tablet 10's.

Yes, it has been observed in some persons that Zam-MT 0.25 Tablet 10's may cause mental or physical dependence if used for a prolonged time. Therefore, take Zam-MT 0.25 Tablet 10's only in dose and duration as advised by your doctor.

Zam-MT 0.25 Tablet 10's is habit-forming and should be used for a short duration in adults and should only be taken after discussing it with doctors. However, taking it for a longer time may cause extreme drowsiness the next day. Thus, one should always take this medication within the prescribed time limit.

Yes, Zam-MT 0.25 Tablet 10's is an addictive or habit-forming medication. Because it makes the brain feel calm and relaxed. So, prolonged usage or overdose may lead to addiction for the brain. Therefore it is important to follow as prescribed by your doctor, especially dose and duration.

Zam-MT 0.25 Tablet 10's is not used for pain relief. It is used to treat sleeplessness (insomnia) and also helps to provide a calming effect on anxiety and panic disorders.

Zam-MT 0.25 Tablet 10's is generally considered safe when used as prescribed by a doctor. However, like all medications, it can have side effects and potential interactions with other drugs. It is important to follow your doctor's instructions and inform them of any pre-existing and existing medical conditions or medication history to avoid negative complications.

No, Zam-MT 0.25 Tablet 10's is not an opioid. It contains alprazolam a benzodiazepine and melatonin a hormone supplement.

Zam-MT 0.25 Tablet 10's has antidepressant properties. Alprazolam alleviates sadness and anxiety, while melatonin regulates sleep and stimulates neurogenesis. Please consult a doctor before using it to ensure safety.

No, Zam-MT 0.25 Tablet 10's is not a narcotic substance. Zam-MT 0.25 Tablet 10's contains alprazolam which is a benzodiazepine and melatonin is a hormone supplement.

Zam-MT 0.25 Tablet 10's is not used for treating a hangover. It is used for anxiety and panic disorders as well as helps to regulate sleep. For hangover relief stay hydrated, have some rest, and consider over-the-counter pain relievers if needed. If it persists or worsens consult a doctor for appropriate treatment.

Yes, you can take Zam-MT 0.25 Tablet 10's for anxiety under medical guidance. But make sure to follow your doctor's instructions strictly to avoid addiction or side effects and have optimal results.

Zam-MT 0.25 Tablet 10's can show the effect of reducing blood pressure through relaxation. But prolonged usage may lead to negative impact. Consult your doctor for personalized advice which is suitable to your condition without causing any side effects.

Generally, Zam-MT 0.25 Tablet 10's does not lead to weight gain. However, an increased or decreased appetite may cause weight gain or weight loss in some people depending on the individual response to the medication. Please talk to your doctor if you have any concerns about weight gain.

No, avoid taking Zam-MT 0.25 Tablet 10's with hydrocodone. As Zam-MT 0.25 Tablet 10's interacts with hydrocodone (a synthetic opioid derivative of codeine) and causes negative side effects. Therefore, it is a better idea to discuss with your doctor before taking any medication while on treatment with Zam-MT 0.25 Tablet 10's to ensure safety.

Generally, taking Zam-MT 0.25 Tablet 10's with paracetamol is safe. However, it is important to consult your doctor before combining medications to ensure there are no potential interactions or side effects specific to your health situation.

No, do not take Zam-MT 0.25 Tablet 10's for the rest of your life as it is a habit-forming or addictive medication.

The common side effects of Zam-MT 0.25 Tablet 10's that may occur in some individuals are drowsiness, tiredness, headache, depressed mood, daytime drowsiness, stomach pain, and dizziness. Most of these side effects of Zam-MT 0.25 Tablet 10's do not require medical attention and gradually resolve over time. However, if these side effects persist or worsen, please consult your doctor.

Country of origin

India

Manufacturer/Marketer address

No. 10, 2nd Cross, Maravaneri, Salem - 636007, Tamil Nadu.
Other Info - ZAM0023

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Author Details

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 18, 2025 | 6:36 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.drugs.com/melatonin.html
  2. https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/018276s052lbl.pdf
whatsapp Floating Button