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compositionComposition:PARACETAMOL-500MG+THIOCOLCHICOSIDE-4MG
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Prescription Medicine
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Xykaa MR 4 Tablet is used to reduce and relieve orthopaedic, traumatic, and rheumatologic disorders. It helps relieve muscle spasms (painful muscular contractions) associated with degenerative vertebral disorders, vertebral static problems, dorsal pain, low back pain, and torticollis (neck muscle contractions). It contains Paracetamol and Thiocolchicoside, which works by inhibiting certain chemical messengers in the brain known as prostaglandins responsible for pain, inflammation and fever. Also, it acts on the centres of the spinal cord and brain and helps relieve muscle stiffness and improves muscle movements, thereby relieves pain due to muscle spasms. In some cases, it may cause side effects such as diarrhoea, drowsiness or stomach pain.

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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

PARACETAMOL-500MG+THIOCOLCHICOSIDE-4MG

Manufacturer/Marketer :

Troikaa Pharmaceuticals Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

NPPA :

Regulated

About Xykaa MR 4 Tablet

Xykaa MR 4 Tablet is a prescription medicine used to relieve painful muscle spasms associated with various muscular and skeletal conditions. It combines a muscle relaxant with a pain reliever to help reduce muscle stiffness, ease discomfort, and improve physical movement. This medicine is commonly prescribed for acute back pain, neck strain, and muscle injuries.

You should take Xykaa MR 4 Tablet exactly as prescribed by your doctor, usually for a short duration of time. It is best to take this medicine with food to prevent an upset stomach, maintaining consistent timing each day. Along with taking this medicine, gentle stretching and staying hydrated can significantly support your recovery.

While taking Xykaa MR 4 Tablet , some people may experience mild side effects such as sleepiness, stomach discomfort, or diarrhoea. If you notice any serious side effects, like severe skin rashes, yellowing of your eyes or skin, or extreme dizziness, you must contact your doctor immediately.

Before starting Xykaa MR 4 Tablet , let your doctor know if you have a history of liver disease, kidney problems, or seizure disorders. Do not take this if you are pregnant, breastfeeding, or a woman of childbearing potential who is not using effective birth control. Thiocolchicoside may harm an unborn baby, so it must not be used during pregnancy.

Avoid drinking alcohol while taking Xykaa MR 4 Tablet , as it can increase drowsiness and raise the risk of liver damage. Elderly individuals and those taking other pain relievers or sedatives should consult their doctor first to prevent harmful drug interactions.

Uses of Xykaa MR 4 Tablet

Xykaa MR 4 Tablet is prescribed to relieve painful muscle spasms and associated musculoskeletal conditions. Common uses include:

  • Painful muscle spasms: Xykaa MR 4 Tablet helps by relaxing tight muscles and blocking pain signals in the body, providing quick relief from acute muscle stiffness.
  • Acute back pain: It targets both the muscle tension and the underlying pain in the lower or upper back, allowing you to move more comfortably.
  • Neck pain and stiffness: Xykaa MR 4 Tablet reduces severe spasms in the neck and shoulder area, helping restore normal range of motion.
  • Muscle injuries: It assists in the recovery process from muscle strains and sprains by easing pain and preventing secondary muscle contractions.

Key Benefits

Xykaa MR 4 Tablet combines a pain reliever with a muscle relaxant to relieve painful muscle spasms and associated discomfort. It helps reduce pain, relax tight muscles, and improve mobility, supporting a faster recovery.

  • Relieves Pain and Muscle Spasms: Helps reduce pain caused by muscle spasms, strains, sprains, and other musculoskeletal conditions.
  • Promotes Muscle Relaxation: Helps relax stiff, tense muscles, reducing muscle tightness and improving comfort.
  • Improves Mobility: By relieving pain and muscle stiffness, it allows easier movement and helps you perform daily activities with less discomfort.
  • Supports Recovery: Better pain control and muscle relaxation help you participate more comfortably in physiotherapy and rehabilitation exercises.
  • Enhances Quality of Life: Reduces muscle-related discomfort, helping improve sleep, physical function, and overall well-being.

Side effects of Xykaa MR 4 Tablet
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
  • Consume more fruits, vegetables, and cruciferous foods like cabbage, kale, and broccoli.
  • Reduced alcohol intake can enhance liver enzyme function.
  • Oxidative stress can be managed by eating foods rich in antioxidants, such as vitamins C and E.
  • Liver function tests regularly can help manage increased levels of AST.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
  • Include iron-rich foods like dark leafy vegetables, lean red meat, legumes and fish in your diet.
  • Consume vitamin C-rich foods as they aid iron absorption.
  • Limit tea, cocoa, and coffee as these can slow iron absorption.
  • Exercise regularly; however, do not overdo it.
  • Rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.
Here are the seven steps to manage medication-triggered Dyspnea (Difficulty Breathing or Shortness of Breath):
  • Tell your doctor immediately if you experience shortness of breath after taking medication.
  • Your doctor may adjust the medication regimen or dosage or give alternative medical procedures to minimize the symptoms of shortness of breath.
  • Monitor your oxygen levels and breathing rate regularly to track changes and potential side effects.
  • For controlling stress and anxiety, try relaxation techniques like deep breathing exercises, meditation, or yoga.
  • Make lifestyle changes, such as quitting smoking, exercising regularly, and maintaining a healthy weight.
  • Seek emergency medical attention if you experience severe shortness of breath, chest pain, or difficulty speaking.
  • Follow up regularly with your doctor to monitor progress, adjust treatment plans, and address any concerns or questions.

Directions for Use

  • Take Xykaa MR 4 Tablet with food to avoid stomach upset or as advised by a doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication, to ensure the safety.
  • Swallow the medicine as a whole with glass of water.
  • Do not crush, break, or chew it.

How Xykaa MR 4 Tablet Works

Xykaa MR 4 Tablet contains paracetamol and thiocolchicoside, which work together to target pain and muscle stiffness simultaneously. The first active component, thiocolchicoside, is a muscle relaxant that works on the brain, spinal cord, and other nerve pathways involved in controlling muscle movement. It acts on GABA and glycine receptors, natural signalling systems that help regulate muscle activity, to reduce painful muscle spasms and stiffness. The second active component, paracetamol, is a widely used pain reliever. Its exact way of working is not fully understood, but it is believed to reduce pain by acting through several pathways in the brain and central nervous system, including lowering the production of prostaglandins, chemicals involved in pain signalling. Together, these two components break the cycle of muscle spasm and pain, providing faster and more comprehensive relief.
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Alcohol

Unsafe

You are recommended to avoid consumption of alcohol with Xykaa MR 4 Tablet as it may increase the risk of liver damage.

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Pregnancy

Unsafe

Xykaa MR 4 Tablet is not recommended for pregnant women as it may cause harm to the foetus. However, please consult your doctor if you are pregnant.

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Breast Feeding

Unsafe

Avoid breastfeeding while taking Xykaa MR 4 Tablet as it may be excreted in breast milk and cause adverse effects in the baby. However, please consult a doctor if you are breastfeeding.

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Driving

Caution

Xykaa MR 4 Tablet may cause drowsiness in some people. Therefore, avoid driving if you feel drowsy after taking Xykaa MR 4 Tablet .

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Liver

Caution

Take Xykaa MR 4 Tablet with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Xykaa MR 4 Tablet with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Unsafe

Xykaa MR 4 Tablet is not recommended for children as the safety and effectiveness were not established.

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Heart

Unsafe

This medicine is not recommended in cardiac patients due to its adverse effects. However, if prescribed extreme caution should be exercised.

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Geriatrics

Caution

Xykaa MR 4 Tablet can be given in elderly patients with caution due to the serious adverse effects.

What if I have taken an overdose of Xykaa MR 4 Tablet

In case of an accidental overdose of Xykaa MR 4 Tablet , seek immediate medical attention or contact a poison control centre right away. Overdosing can lead to serious health complications, particularly liver damage or severe drowsiness

Diet & Lifestyle Advise

  • Apply mild heat or cold packs: Use a warm compress or ice pack on the affected muscles for 15–20 minutes at a time to help soothe inflammation and ease stiffness.
  • Stay hydrated: Drink plenty of water throughout the day, as dehydration can worsen muscle cramps and spasms.
  • Incorporate gentle stretching: Under the guidance of your physiotherapist, perform light stretching exercises to maintain muscle flexibility and range of motion.
  • Avoid heavy lifting: Rest your muscles and avoid lifting heavy objects or performing high-impact activities while recovering from a spasm.
  • Maintain good posture: Use ergonomic chairs and pay attention to your sitting and standing posture to prevent putting extra strain on your back and neck muscles.
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How Soon It Starts Working

The time required for Xykaa MR 4 Tablet to start to work: Xykaa MR 4 Tablet ideally shows its action within 30 minutes to 1 hour after administration. The time for which the effects of Xykaa MR 4 Tablet last: The effect of Xykaa MR 4 Tablet lasts for 4 to 6 hours.

What if you forget to take Xykaa MR 4 Tablet

If you miss a dose of Xykaa MR 4 Tablet , take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and resume your regular dosing schedule. Do not take a double dose to make up for a missed one.

Storage

•Store Xykaa MR 4 Tablet at controlled room temperature, safely between 15°C and 30°C (59°F to 86°F). •Do not store this medicine in the bathroom or areas with high humidity, and never allow it to freeze.

Drug Warnings

  • Limit your treatment duration: Do not use Xykaa MR 4 Tablet for longer than the short course prescribed by your doctor (typically limited to a maximum of 7 consecutive days) to avoid potential cellular side effects.
  • Avoid driving or operating machinery: Because this medicine can make you feel sleepy or dizzy, do not drive or use heavy machinery until you know how it affects you.
  • Avoid double-dosing on pain relievers: Do not take any other over-the-counter pain medications containing the same pain-relieving ingredient, as this can lead to an accidental overdose and severe liver damage.
  • Check packaging integrity: Before taking your dose, inspect the blister strip. If the packaging is torn, punctured, or if the tablets look discoloured, do not consume them.
  • Consult if you plan to conceive: Women of childbearing potential should use reliable birth control while taking this medicine, as it is not recommended for those planning a pregnancy.

Drug-Drug Interactions

verifiedApollotooltip

name may interact with certain medicines. Inform your doctor if you are taking any of the following:

  • Other products containing pain relievers: Combining Xykaa MR 4 Tablet with other medications that contain the same pain-relieving agent can cause severe liver damage.
  • Sleeping pills, sedatives, or anxiety medications: Taking these alongside Xykaa MR 4 Tablet can significantly increase drowsiness, sleepiness, and the risk of respiratory depression.
  • Blood thinners (like warfarin): Regular or long-term use of the pain-relieving component in Xykaa MR 4 Tablet may slightly increase the risk of bleeding when taken with anticoagulants.
Paracetamol + ThiocolchicosideLomitapide
Severe
Paracetamol + ThiocolchicosideKetoconazole
Severe

Drug-Drug Interactions

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Paracetamol + ThiocolchicosideLomitapide
Severe
How does the drug interact with Xykaa MR 4 Tablet:
Co-administration of Lomitapide and Paracetamol and Thiocolchicoside may increase the risk of severity of liver injury.

How to manage the interaction:
Although there is a possible interaction between Paracetamol and Thiocolchicoside and Lomitapide, you can take these medicines together if prescribed by a doctor. However, consult a doctor if you experience fever, joint pain or swelling, vomiting, abdominal pain, dark urine, or yellowing of the skin or eyes. Do not stop using any medications without a doctor's advice.
Paracetamol + ThiocolchicosideKetoconazole
Severe
How does the drug interact with Xykaa MR 4 Tablet:
Co-administration of Paracetamol and Thiocolchicoside and Ketoconazole may increase the risk of liver injury.

How to manage the interaction:
Although there is a possible interaction between Paracetamol and Thiocolchicoside and Ketoconazole, you can take these medicines together if prescribed by a doctor. However, if you have joint pain or swelling, fever, vomiting, stomach pain, dark-colored urine, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue the medication without consulting a doctor.
Paracetamol + ThiocolchicosideLeflunomide
Severe
How does the drug interact with Xykaa MR 4 Tablet:
Co-administration of Paracetamol and Thiocolchicoside and Leflunomide may increase the risk of liver problems.

How to manage the interaction:
Although there is a possible interaction between Paracetamol and Thiocolchicoside with Leflunomide, they can be taken together if prescribed by a doctor. However, if you experience fever, joint pain or swelling, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Paracetamol + ThiocolchicosideEthanol
Severe
How does the drug interact with Xykaa MR 4 Tablet:
Co-administration of Xykaa MR 4 Tablet with Ethanol may increase the risk of liver injury.

How to manage the interaction:
Taking Ethanol and Xykaa MR 4 Tablet together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience any symptoms such as fever, chills, joint pain or swelling, excessive tiredness or weakness, unusual bleeding or bruising, skin rash or itching, loss of appetite, nausea, vomiting, or yellowing of the skin or the whites of your eyes, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
Paracetamol + ThiocolchicosideTeriflunomide
Severe
How does the drug interact with Xykaa MR 4 Tablet:
Co-administration of Teriflunomide with Paracetamol and Thiocolchicoside may increase the risk or severity of Liver problems.

How to manage the interaction:
Taking Paracetamol and Thiocolchicoside with Teriflunomide together can result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor if you experience fever, joint pain or swelling, vomiting, abdominal pain, dark-colored urine, or yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.
Paracetamol + ThiocolchicosideMipomersen
Severe
How does the drug interact with Xykaa MR 4 Tablet:
Co-administration of Mipomersen with Paracetamol and Thiocolchicoside may increase the risk or severity of liver injury.

How to manage the interaction:
There may be a possibility of interaction between Paracetamol and Thiocolchicoside and Mipomersen, but it can be taken if prescribed by a doctor. However, consult a doctor if you experience fever, joint pain or swelling, vomiting, abdominal pain, or yellowing of the skin or eyes. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

verifiedApollotooltip

Certain foods and beverages may affect how Xykaa MR 4 Tablet works. Inform your doctor if you regularly consume any of the following:

  • Alcohol: Drinking alcohol while taking Xykaa MR 4 Tablet increases the risk of severe drowsiness and heightens the risk of acute liver damage.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[MUSCLE RELAXANTS]

FAQs

Xykaa MR 4 Tablet is used to reduce and relieve orthopaedic, traumatic, and rheumatologic disorders. It helps relieve muscle spasms (painful muscular contractions) associated with degenerative vertebral disorders, vertebral static problems, dorsal pain, low back pain, and torticollis (neck muscle contractions).
Xykaa MR 4 Tablet contains Paracetamol and Thiocolchicoside. Paracetamol is an analgesic (relieves pain) and antipyretic (reduces fever) that works by inhibiting the production of certain chemical messengers in the brain known as prostaglandins responsible for pain and fever. Thiocolchicoside is a skeletal muscle relaxant that works on the centers of the spinal cord and brain. This helps relieve muscle stiffness and improves muscle movements, thereby relieves pain due to muscle spasms.
Xykaa MR 4 Tablet may affect sperm cells and thereby causes problems with male fertility. Therefore, please consult your doctor before taking Xykaa MR 4 Tablet .
Xykaa MR 4 Tablet may cause diarrhoea as a side effect. It is not necessary for everyone taking Xykaa MR 4 Tablet to experience this side effect. However, if the condition persists or worsens, please consult a doctor.
You are not recommended to take Xykaa MR 4 Tablet with warfarin (blood thinner) as co-administration of these two medicines may increase bleeding risk. So you are advised to contact your doctor so that the dose may be adjusted appropriately to use safely.
Xykaa MR 4 Tablet may trigger episodes of epilepsy (fits), especially in patients who are at risk for fits or those suffering from fits. Therefore, please inform your doctor if you have a history of fits before taking Xykaa MR 4 Tablet .
You are recommended to use Xykaa MR 4 Tablet for as long as your doctor has prescribed it. However, if the symptoms persist even after using Xykaa MR 4 Tablet for 7 days, stop taking Xykaa MR 4 Tablet and consult a doctor.
Though Xykaa MR 4 Tablet contains paracetamol it is not used to reduce fever. Xykaa MR 4 Tablet is used to relieve musculoskeletal pain and spasms.
Xykaa MR 4 Tablet may cause side effects like diarrhoea, drowsiness or stomach pain. Most of these side effects of Xykaa MR 4 Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
Xykaa MR 4 Tablet should be swallowed as a whole with water; do not crush or chew it.
Xykaa MR 4 Tablet may cause drowsiness in some people. Therefore, avoid driving if you feel drowsy after taking Xykaa MR 4 Tablet . You are recommended to avoid consumption of alcohol with Xykaa MR 4 Tablet as it may increase the risk of liver damage.
Xykaa MR 4 Tablet is not recommended for children as the safety and effectiveness were not established.
While you can take it without food, it is highly recommended to take Xykaa MR 4 Tablet with or after a meal. This helps prevent stomach upset and irritation. Talk to your doctor or pharmacist if you experience persistent digestive issues.
No, you should strictly avoid alcohol while on this medication. Alcohol increases the risk of extreme sleepiness and significantly raises the danger of liver damage. Talk to your doctor if you have concerns about alcohol use.
No, Xykaa MR 4 Tablet is not recommended for pregnant or breastfeeding women, as it contains active ingredients that may carry risks for the developing baby. If you are planning to become pregnant, talk to your doctor about safer alternatives.
This medication is designed for short-term, acute relief. Using the muscle-relaxing component for longer periods is not recommended due to potential safety risks at the cellular level. Always follow the duration recommended by your physician, and talk to your doctor if pain persists.
Yes, drowsiness is a common side effect of Xykaa MR 4 Tablet because of its muscle-relaxing component. Avoid driving, operating heavy machinery, or performing tasks that require full mental alertness until you know how the medicine affects you. Talk to your doctor if the sleepiness is severe.
You should avoid taking other over-the-counter pain medications, especially those containing the same pain-relieving ingredient, to prevent accidental overdose and potential liver damage. Talk to your doctor or pharmacist before combining any medications.
If your symptoms do not improve or if they get worse after completing your prescribed course of Xykaa MR 4 Tablet , do not continue taking the medication on your own. Talk to your doctor for a comprehensive re-evaluation of your condition.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

Troikaa Pharmaceuticals Ltd., Registered Office: , 'Commerce House - 1', Satya Marg, Bodakdev, Ahmedabad-380 054. Gujarat, India.
Other Info - XYK0007

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