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Xultophy 3ml Pre-Filled Pen is used to treat type-2 diabetes mellitus adjunct to diet and exercise. It contains Liraglutide and Insulin degludec which helps control blood glucose and insulin levels by facilitating the reuptake of glucose in the fat and muscle cells. It helps control blood sugar levels in people with diabetes thereby preventing serious complications of diabetes like kidney damage and blindness.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Manufacturer/Marketer :

Abbott India Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Xultophy 3ml Pre-Filled Pen

Xultophy 3ml Pre-Filled Pen is a prescription injectable medication used to improve blood sugar control in adults with type 2 diabetes mellitus. It is prescribed when oral diabetes medicines or single-agent insulins are not enough to manage blood sugar levels. This medicine helps lower HbA1c levels and reduces the risk of serious diabetes complications.

You will typically inject Xultophy 3ml Pre-Filled Pen once daily, at the same time each day, with or without food. To get the best results, it is important to use this medication consistently as part of a comprehensive management plan. Combining this treatment with a balanced diet and regular physical activity significantly enhances its effectiveness.

While using Xultophy 3ml Pre-Filled Pen, you may experience common side effects like nausea, diarrhoea, or mild low blood sugar. However, you must contact your doctor immediately if you experience severe abdominal pain, persistent vomiting, or signs of a serious allergic reaction.

Talk to your doctor before starting Xultophy 3ml Pre-Filled Pen if you have a history of pancreas problems, kidney disease, or severe stomach issues. Do not take this if you or anyone in your family has ever had a type of thyroid cancer called medullary thyroid carcinoma, or if you have Multiple Endocrine Neoplasia syndrome type 2.

This medication can interact with alcohol, which can unpredictably raise or lower your blood sugar levels. If you are pregnant, planning to become pregnant, breastfeeding, or are an elderly individual, consult your doctor before using Xultophy 3ml Pre-Filled Pen, as special precautions or dosage adjustments may be necessary.

Uses of Xultophy 3ml Pre-Filled Pen

Xultophy 3ml Pre-Filled Pen is used to treat Type 2 diabetes mellitus. The detailed uses of Xultophy 3ml Pre-Filled Pen are as follows:

  • Type 2 Diabetes Mellitus: Xultophy 3ml Pre-Filled Pen helps lower high blood glucose levels in adults when diet, exercise, and other diabetes medications do not provide adequate blood sugar control.

Key Benefits

Xultophy 3ml Pre-Filled Pen helps manage type 2 diabetes by combining two blood sugar-lowering medicines in a single daily injection. With regular use, it provides steady blood sugar control, supports long-term diabetes management, and offers the convenience of a simplified treatment routine.

  • Provides Effective Blood Sugar Control: By mimicking natural hormones and improving blood sugar regulation, this medicine helps reduce blood sugar spikes after meals and maintains healthy glucose levels throughout the day.
  • Supports Long-Term Diabetes Management: Consistent use helps lower HbA1c levels and reduces the risk of diabetes-related complications, including nerve damage, kidney disease, and vision problems.
  • Convenient Once-Daily Treatment: By combining two blood sugar-lowering medicines in a single daily injection, this treatment simplifies diabetes management and may also help support stable body weight or modest weight loss in some patients.
Side effects of Xultophy 3ml Pre-filled Pen
Here are the steps to manage the medication-triggered Common Cold:
  • Inform your doctor about the common cold symptoms you're experiencing due to medication.
  • Your doctor may adjust your treatment plan, which could include changing your medication, adding new medications, or offering advice on managing your symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Drink plenty of fluids, such as warm water or soup, to help thin out mucus.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your symptoms don't subside or worsen, consult your doctor for further guidance.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.

Directions for Use

  • Xultophy 3ml Pre-Filled Pen is recommended once daily, preferably at the same time each day, or as advised by your doctor.
  • Check the label for instructions before using Xultophy 3ml Pre-Filled Pen.
  • It should be administered subcutaneously (under the skin) only.
  • Wash your hands properly and adjust the dose as advised by the doctor. Clean the injection site and inject the dose subcutaneously in the abdomen/thighs/upper arm. Safely discard the needle.
  • Change injection sites within the same area to prevent the formation of hard lumps.
  • Do not administer Xultophy 3ml Pre-Filled Pen intravenously, intramuscularly, or by an infusion pump.

How Xultophy 3ml Pre-Filled Pen Works

Xultophy 3ml Pre-Filled Pen contains two active medicines that work together in different ways to control your blood sugar levels. The first component, insulin degludec, a long-acting basal insulin, mimics the insulin naturally produced by your pancreas. Once injected, it is released slowly and continuously into your bloodstream. This provides a steady supply of insulin throughout the day and night, helping your body's cells absorb sugar from the blood and reducing the amount of sugar your liver produces. The second component, liraglutide, a glucagon-like peptide-1 (GLP-1) receptor agonist, works by stimulating your pancreas to release more insulin when your blood sugar is high, especially after eating. It also slows down the passage of food through your stomach, which helps prevent sudden blood sugar spikes, and decreases the release of glucagon, a hormone that raises blood sugar. Together, these two components provide comprehensive, round-the-clock control over your blood sugar levels.
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Alcohol

Unsafe

You are recommended to avoid alcohol consumption while using Xultophy 3ml Pre-Filled Pen as alcohol might affect blood sugar levels.

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Pregnancy

Caution

Consult your doctor if you are pregnant; your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Consult your doctor if you are breastfeeding; your doctor will prescribe only if the benefits outweigh the risks.

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Driving

Caution

Xultophy 3ml Pre-Filled Pen may cause hypoglycaemia. So, drive, and operate machinery only if you are alert.

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Liver

Caution

Dose adjustment may be needed. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Xultophy 3ml Pre-Filled Pen is not recommended for children below 18 years as the effectiveness has not been established.

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Heart

Caution

Dose adjustment may be needed. Please consult your doctor if you have heart problems or any concerns regarding this.

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Geriatrics

Caution

Xultophy 3ml Pre-Filled Pen should be administered with caution in elderly patients due to an increased risk of side effects. Seek medical advice if you have any concerns.

What if I have taken an overdose of Xultophy 3ml Pre-Filled Pen

If you inject too much Xultophy 3ml Pre-Filled Pen, it can cause dangerously low blood sugar (hypoglycemia) or severe nausea and vomiting. Seek emergency medical attention immediately. Keep a source of fast-acting sugar, like fruit juice or glucose tablets, nearby in case you experience mild overdose symptoms.

Diet & Lifestyle Advise

  • Monitor carbohydrates: Work with a dietitian to learn how to count carbs and distribute them evenly throughout the day to avoid sudden blood sugar fluctuations.
  • Stay active: Engage in at least 150 minutes of moderate-intensity aerobic exercise, such as brisk walking, per week. Exercise helps your body use insulin more efficiently.
  • Keep fast-acting sugar nearby: Always carry glucose tablets, hard candies, or fruit juice with you to quickly treat sudden episodes of low blood sugar.
  • Stay hydrated: Drink plenty of water throughout the day, especially if you experience mild diarrhoea or nausea, to prevent dehydration.
  • Track your blood sugar: Keep a daily log of your blood sugar readings and share them with your healthcare team to help fine-tune your treatment plan.
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How Soon It Starts Working

The time required for Xultophy 3ml Pre-Filled Pen to start to work: Xultophy 3ml Pre-Filled Pen ideally shows its action within 1 hour of administration. The time for which the effects of Xultophy 3ml Pre-Filled Pen last: The effect of Xultophy 3ml Pre-Filled Pen last for 24 hours.

What if you forget to take Xultophy 3ml Pre-Filled Pen

If you miss a dose of Xultophy 3ml Pre-Filled Pen, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and resume your regular daily schedule. Do not take a double dose or increase your dose to make up for a missed one. If you miss your dose for more than three consecutive days, contact your doctor for advice on how to restart.

Storage

• Store unused, unopened Xultophy 3ml Pre-Filled Pen pens in their original packaging in the refrigerator at a temperature between 2°C and 8°C. Do not freeze. Keep them away from the cooling element.
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Keep Refrigerated. Do not freeze.Prepaid payment required.

Drug Warnings

  • Inspect the liquid: Always check the window of your Xultophy 3ml Pre-Filled Pen pen before injecting. The liquid must be clear and colourless; do not inject if you see cloudiness, discolouration, or floating particles.
  • Rotate injection sites: Change your injection site with each dose within the area you choose (abdomen, thigh, or upper arm) to reduce the risk of developing hard lumps or skin thickening under the skin.
  • Never share pens: Even if the needle is changed, never share your Xultophy 3ml Pre-Filled Pen pen with anyone else. Sharing can pass serious infections or diseases from one person to another.
  • Always use a new needle: Attach a fresh, sterile needle before every single injection. Reusing needles increases the risk of contamination, blockages, infection, and inaccurate dosing.
  • Check for pancreatitis: Stop using the medicine and contact your doctor immediately if you develop severe, persistent stomach pain that radiates to your back, as this can be a sign of acute pancreatitis.

Drug-Drug Interactions

verifiedApollotooltip
  • Other diabetes medications: Taking this medicine alongside other blood-sugar-lowering drugs, such as sulfonylureas or other insulins, may significantly increase your risk of low blood sugar. Your doctor may need to adjust your doses.
  • Blood pressure medicines (Beta-blockers): These medicines can mask the warning signs of low blood sugar, such as a fast heartbeat or palpitations, making it harder for you to recognise hypoglycemia.
  • Corticosteroids and thyroid hormones: These medicines can raise your blood sugar levels, potentially reducing the effectiveness of Xultophy 3ml Pre-Filled Pen.
No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

verifiedApollotooltip
  • Alcohol: Consuming alcohol while using Xultophy 3ml Pre-Filled Pen can cause unpredictable blood sugar levels and increase the risk of severe low blood sugar. Avoid drinking alcohol or talk to your doctor about safe limits.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[ANTIDIABETICS]

FAQs

Xultophy 3ml Pre-Filled Pen is used to treat type-2 diabetes mellitus adjunct to diet and exercise.
Xultophy 3ml Pre-Filled Pen contains Liraglutide and Insulin degludec. Liraglutide lowers the amount of sugar made by the body and helps the body make more insulin during meals. Insulin degludec works similarly to the insulin produced by the body. It lowers blood glucose levels and facilitates the reuptake of glucose in the fat and muscle cells. Together, Xultophy 3ml Pre-Filled Pen helps in controlling blood glucose levels.
Xultophy 3ml Pre-Filled Pen may sometimes lower the blood glucose levels more than normal, leading to hypoglycaemia. Regularly monitor your blood sugar levels while taking Xultophy 3ml Pre-Filled Pen. Always carry any sugary food and consume it if you experience hypoglycaemia symptoms such as headache, drowsiness, cold sweat, feeling sick, unusual tiredness or weakness, and visual disturbances.
Hypoglycaemia may occur following prolonged or severe exercise, during illness, alcohol consumption, low food intake, or when Xultophy 3ml Pre-Filled Pen is taken along with other antidiabetic medicines.
Maintain a healthy diet by regular intake of carbohydrates such as bread and products containing starch and sugar. Eat your meals regularly, and do not exercise heavily for longer durations with an empty stomach.
Do not stop using Xultophy 3ml Pre-Filled Pen without consulting your doctor as it may cause an increase in blood glucose levels. Continue taking Xultophy 3ml Pre-Filled Pen for as long as your doctor has prescribed it to you. Do not be reluctant to speak with your doctor if you experience any difficulty while using Xultophy 3ml Pre-Filled Pen.
Before opening, store Xultophy 3ml Pre-Filled Pen in a refrigerator at 2°C to 8°C. Do not freeze. Once in use, you can keep the pre-filled pen at room temperature (below 30°C) or in the refrigerator for up to 21 days. Discard the pen 21 days after first use, even if some medicine remains. Always keep the pen cap on when not in use to protect it from light. Talk to your doctor or pharmacist if you have any questions about storage.
Xultophy 3ml Pre-Filled Pen is approved only for managing type 2 diabetes. While some patients may lose weight as a secondary effect of the treatment, it is not approved as a primary weight loss product. Talk to your doctor for advice on weight management.
You should inject Xultophy 3ml Pre-Filled Pen once daily at the same time every day. Choose a time that easily fits into your daily routine to help you remember. Talk to your doctor to find the best schedule for you.
You can inject Xultophy 3ml Pre-Filled Pen at any time of day, with or without food. It does not need to be timed around your meals, but keeping your daily injection time consistent is important. Talk to your doctor if you experience nausea when taking it.
No, you must never share your Xultophy 3ml Pre-Filled Pen pen with anyone else, even if you change the needle. Sharing pens carries a high risk of spreading blood-borne infections. Talk to your pharmacist about proper pen safety.
If you feel symptoms of low blood sugar (like shaking, sweating, or dizziness), consume 15 to 20 grams of fast-acting sugar, such as fruit juice, raisins, or glucose tablets. Recheck your blood sugar after 15 minutes. Talk to your doctor if this happens frequently.
Xultophy 3ml Pre-Filled Pen is generally not recommended during pregnancy or while breastfeeding. Your doctor will likely recommend alternative methods to control your blood sugar during this time. Talk to your doctor if you are pregnant or planning to become pregnant.
The recommended injection areas are your front thighs, your abdomen (stomach area), or your upper arms. Remember to rotate your injection site within these areas with each dose to avoid skin changes. Talk to your doctor or nurse if you need help practising your injection technique.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

401, LSC, C-Block, Mohan Place Saraswati Vihar Delhi Dl 110034 INDIA
Other Info - XUL0003
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