Apollo
logo

Welcome User

Login/Sign Up

Home
Buy Medicines
Lab Tests
Doctor Consult
Circle Membership
insurance
Blogs
Contact Us
Privacy Policy
Return & Refunds
Need Help
Terms and Conditions
Select Delivery Location
compositionComposition:GILTERITINIB-40MG
prescription
Prescription Medicine
info
image icons
Best Price

₹4278582 with coupons*

View

Xospata 40 mg Tablet 21's is used to treat acute myeloid leukaemia (AML). It contains Gilterinib, which works by inhibiting the FLT3 tyrosine kinase, which is often mutated in AML patients. It may cause common side effects such as fatigue, fever, mucositis (inflammation of the mucosa), edema, rash, non-infectious diarrhea, dyspnea (feeling short of breath), nausea, cough, constipation, headache, dizziness, and vomiting. Before using Xospata 40 mg Tablet 21's, you should inform your doctor about all the medications you are are taking, if you are allergic to any of its ingredients and pre-existing medical conditions. Xospata 40 mg Tablet 21's is not recommended to use during pregnancy as it may harm your unborn baby, and not to breastfeed during treatment with Xospata 40 mg Tablet 21's for at least 2 months after the final dose.

Read more
Written By ,
Reviewed By Dr. Lakshmithulasi Yarragunta , PharmD (PB)
OffersOffers & Discounts

Get Free delivery (₹99) with circle icon

Join Circle
coupon
Get Extra 2% Off with Coupons
coupon
Extra 10% Off with Bank Offers
bank offer
bank offer
bank offer

More about the Product

Composition :

GILTERITINIB-40MG

Manufacturer/Marketer :

Astellas Pharma India Pvt Ltd

Consume Type :

Oral

Expires on or after :

Jan-28

Return Policy :

Not Returnable

About Xospata 40 mg Tablet 21's

Xospata 40 mg Tablet 21's is a prescription medication used to treat adults with a specific type of blood and bone marrow cancer called acute myeloid leukemia. This medicine is also available under the brand name Xospata. Depending on your prescription or pharmacy, you may see either the brand name or the generic name (gilteritinib) on the medicine label. It is specifically prescribed when the cancer cells have a unique genetic change known as a FLT3 mutation. This medicine is typically used when the cancer has returned or has not improved after previous treatments. Before starting treatment, your doctor will confirm that your leukemia has a FLT3 mutation using a validated laboratory test. This medicine is only effective for AML with this specific genetic change, so testing is an essential step before treatment begins.

To get the best results, you must take this medicine exactly once every day at the same time. You can take it either with food or on an empty stomach, but keeping a consistent routine is key. Making healthy adjustments to your daily routine, such as staying well-hydrated and eating balanced meals, can also support your body during treatment.

While taking this medicine, you may experience common side effects like tiredness, joint pain, or mild nausea. However, it is vital to contact your healthcare provider immediately if you experience serious symptoms like extreme shortness of breath, sudden weight gain, severe headaches, or unusual rhythm changes in your heart.

Before you begin treatment, tell your doctor if you have a history of heart rhythm problems, liver issues, or kidney disease. Do not take this if you are pregnant, as this medication can harm an unborn baby. Women who can get pregnant must use effective birth control during treatment and for several months afterwards. This medicine may also affect male fertility. If you plan to have children in the future, talk to your doctor about fertility preservation options, such as sperm banking, before starting treatment.

Some medicines can interfere with how this drug works, so it is important to share a complete list of your current prescriptions with your pharmacist. Avoid drinking alcohol or smoking while on this treatment, as they can put extra stress on your liver and heart. If you are breastfeeding or are an older adult, talk to your doctor about the specific precautions you need to take.

Uses of Xospata 40 mg Tablet 21's

Your doctor may prescribe Xospata 40 mg Tablet 21's to help manage the following conditions:

  • Acute Myeloid Leukemia (AML): Xospata 40 mg Tablet 21's is used to treat adults with AML that has a specific genetic change (FLT3 mutation) when the disease has returned after earlier treatment (relapsed AML) or has not responded well to previous treatment (refractory AML). It works by blocking signals that help these cancer cells grow and multiply. 

Key Benefits

  • Targeted Cancer Cell Control & Improved Quality of Life: This medication offers targeted relief by focusing directly on mutated cancer cells rather than all fast-growing cells in the body. By blocking the abnormal proteins that feed the leukemia, it helps stop the disease from spreading. This can lead to a significant reduction in cancer cells in your blood and bone marrow, helping you work toward remission. Over time, managing the cancer effectively can help you regain your physical strength, reduce severe fatigue, and improve your overall quality of life. For some eligible patients, this treatment may also help control the leukemia while they are being prepared for an allogeneic stem cell transplant. Your doctor will discuss whether this is an appropriate treatment goal based on your individual condition. 

Directions for Use

  • Xospata 40 mg Tablet 21's can be taken with or without food.
  • Follow your doctor’s instructions on the dosage and timing of this medication to ensure safe and effective use.
  • Swallow Xospata 40 mg Tablet 21's as a whole with a glass of water.
  • Do not crush, chew or break it.

How Xospata 40 mg Tablet 21's Works

This medicine works as a targeted therapy known as a kinase inhibitor. In some types of leukemia, cancer cells have a mutated gene called FLT3, which produces an abnormal protein that constantly tells the cells to grow and divide. When you take GILTERITINIB, the active medicine travels through your bloodstream and binds to these abnormal FLT3 proteins. By blocking this signal, the medicine effectively cuts off the growth command, causing the cancer cells to stop multiplying and eventually die off. This specific targeting helps spare many healthy cells from being destroyed.
bannner image

Alcohol

Consult your doctor

It is not known if alcohol affects Xospata 40 mg Tablet 21's. Please consult your doctor.

bannner image

Pregnancy

Unsafe

Xospata 40 mg Tablet 21's is not recommended during pregnancy as it may harm your unborn baby. If you are pregnant or planning to become pregnant, consult your doctor for guidance and advice.

bannner image

Breast Feeding

Unsafe

Xospata 40 mg Tablet 21's may harm the baby; do not breastfeed during treatment with Xospata 40 mg Tablet 21's for at least 2 months after the final dose.

bannner image

Driving

Caution

Xospata 40 mg Tablet 21's may cause dizziness and vertigo. Be cautious while driving or operating machinery.

bannner image

Liver

Consult your doctor

If you have a history of liver disease, inform your doctor before taking Xospata 40 mg Tablet 21's. Your doctor may adjust your dosage or recommend a different medication based on your individual needs and condition.

bannner image

Kidney

Caution

Xospata 40 mg Tablet 21's exposure may be increased in patients with severe renal impairment or end-stage renal disease. Therefore, inform your doctor if you have any renal impairment.

bannner image

Children

Unsafe

The safety and effectiveness of Xospata 40 mg Tablet 21's in children below 18 years have not been established.

bannner image

Heart

Consult your doctor

If you have a heart disease or any related concerns, Please consult your doctor before using Xospata 40 mg Tablet 21's.

bannner image

Geriatrics

Consult your doctor

Please consult your doctor before giving Xospata 40 mg Tablet 21's to elderly people.

What if I have taken an overdose of Xospata 40 mg Tablet 21's

If you suspect an overdose or have taken more than your prescribed dose, seek emergency medical attention.

Diet & Lifestyle Advise

  • Avoid grapefruit products: Do not eat grapefruit or drink grapefruit juice while taking this medicine. Grapefruit can increase the amount of the drug in your body to unsafe levels.
  • Stay hydrated: Drink plenty of water throughout the day to help manage potential side effects like diarrhea or nausea.
  • Practice gentle mouth care: Use a soft-bristled toothbrush and rinse your mouth regularly with salt water or a baking soda solution to help prevent or soothe mouth sores. Avoid harsh, alcohol-based mouthwashes.
  • Protect your immune system: Since this medication can temporarily lower your white blood cell count, wash your hands frequently and avoid close contact with people who are sick.
  • Eat small, frequent meals: If you experience nausea or a loss of appetite, eating smaller portions throughout the day rather than three large meals can help maintain your nutrition and energy levels.
health query

Have a query?

How Soon It Starts Working

The time required for Xospata 40 mg Tablet 21's to start to work: The peak effect of Xospata 40 mg Tablet 21's can be observed within 2-4 hours of administration. The time for which the effects of Xospata 40 mg Tablet 21's last: The effect of Xospata 40 mg Tablet 21's usually lasts up to 24 hours approximately.

What if you forget to take Xospata 40 mg Tablet 21's

If you miss a dose, take it as soon as you remember on that same day. However, if your next scheduled dose is less than 12 hours away, skip the missed dose entirely and return to your normal schedule. Do not take two doses at the exact same time or within 12 hours of each other.

Storage

•Keep the tablets in their original packaging to protect them from light and moisture.

Drug Warnings

  • Get regular heart checks: Your doctor will perform electrocardiograms (ECGs) to monitor your heart rhythm while you are on this medicine.
  • Monitor your blood work: Regular monitoring helps your doctor see how well the treatment is working and identify side effects early. You may also have electrocardiograms (ECGs) and other tests at scheduled intervals throughout your treatment, and your doctor will adjust your care based on these results.
  • Do not touch broken tablets: Pregnant women or those planning to become pregnant should not handle broken or damaged tablets.
  • Watch for sudden breathing changes: Seek immediate help if you experience a cough, fever, and difficulty breathing, as this can be a life-threatening reaction.
  • Avoid driving if dizzy: This medicine can make you feel dizzy or lightheaded. Do not drive or operate heavy machinery until you know how it affects you.

verifiedApollotooltip
  • Strong CYP3A inhibitors: Certain medicines used to treat fungal or bacterial infections can slow down how your body processes Xospata 40 mg Tablet 21's, increasing the risk of serious side effects.
  • Strong CYP3A inducers: Some medications used to treat seizures or tuberculosis can speed up how your body breaks down Xospata 40 mg Tablet 21's, making it less effective.
  • Heart rhythm medicines: Taking this medication with other drugs that affect your heart's electrical activity (such as certain antiarrhythmics or antipsychotics) can increase the risk of dangerous heart rhythm changes.

Login/Sign Up

verifiedApollotooltip
  • Grapefruit and grapefruit juice: Consuming these can block the enzymes that break down Xospata 40 mg Tablet 21's, leading to dangerously high levels of the medicine in your bloodstream.

Login/Sign Up

Habit Forming

No

Therapeutic Class

[KINASE INHIBITORS]

FAQs

Xospata 40 mg Tablet 21's is used in the treatment of acute myeloid leukaemia (AML).
Xospata 40 mg Tablet 21's contains gilteritinib, which inhibits the activity of the enzyme FLT3 (FMS-like tyrosine kinase 3). This enzyme is crucial for the growth and survival of certain cancer cells. By blocking the activity of FLT3, gilteritinib helps stop the growth and division of cancer cells, leading to their death. This targeted approach makes gilteritinib an effective treatment for AML patients with FLT3 mutations.
If you miss a dose of Xospata 40 mg Tablet 21's, take your next dose at the scheduled time. Do not take an extra dose to compensate for a missed dose.
Continue taking Xospata 40 mg Tablet 21's even if you feel well. Do not stop taking Xospata 40 mg Tablet 21's without talking to the doctor.
Take Xospata 40 mg Tablet 21's with or without food. Swallow the medicine whole with a full glass of water without crushing or chewing it.
The common side effects of Xospata 40 mg Tablet 21's are fatigue, fever, mucositis (inflammation of the mucosa), edema, rash, non-infectious diarrhoea, dyspnea (feeling short of breath), nausea, cough, constipation, eye disorders, headache, dizziness, vomiting. If these side effects persist or worsen, please consult your doctor.
If you vomit after taking your dose, do not take an extra tablet to make up for it. Simply wait and take your next dose at your regularly scheduled time the next day. Talk to your doctor or pharmacist for further guidance.
Even after treatment ends, your doctor will continue to monitor your recovery with follow-up appointments and blood tests to check how your leukemia is responding and to watch for any ongoing or returning side effects. Always attend your scheduled follow-up visits and contact your healthcare team if you develop new or worsening symptoms after stopping treatment.
No, you must avoid grapefruit and grapefruit juice because they can significantly increase the concentration of the medication in your body, raising your risk of dangerous side effects.
Hair thinning or loss is not a commonly reported side effect of this specific medication, though everyone reacts differently. Talk to your doctor or pharmacist if you notice unusual changes in your hair.
No, you should not take this medicine if you are pregnant or planning a pregnancy, as it can cause serious harm to an unborn baby. Both men and women should use effective birth control during treatment. Talk to your doctor for specific advice.
One of the most serious conditions is differentiation syndrome, which affects your blood cells. Call your doctor immediately if you develop a fever, cough, trouble breathing, or sudden weight gain.
No, you must swallow the tablet whole with a glass of water. Do not crush, break, or chew the tablet, as it may affect how the drug is absorbed. Talk to your doctor or pharmacist if you have trouble swallowing pills.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

UNIT NO. 301, 'C & B SQUARE',CTS NO. 95 A,127 ANDHERI KURLA RD, VILLAGE CHAKALA, ANDHERI (EAST) MUMBAI Mumbai City MH 400069 IN
Other Info - XOS0004
whatsapp Floating Button
Buy Now
Add to Cart