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compositionComposition:HYDROCHLOROTHIAZIDE-12.5MG+IRBESARTAN-150MG
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Prescription Medicine
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Xarb H Tablet is used to treat high blood pressure. It contains Irbesartan and Hydrochlorothiazide which work by relaxing and widening the narrowed blood vessels, improving blood flow and removing extra water/fluid and certain electrolyte overload from the body. In some cases, this medicine may cause side effects such as nausea, taste change, upset stomach, diarrhoea, dizziness, headache, and decreased blood pressure. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By Lakshmithulasi Yarragunta , PharmD (PB)
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
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More about the Product

Composition :

HYDROCHLOROTHIAZIDE-12.5MG+IRBESARTAN-150MG

Manufacturer/Marketer :

Abbott India Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Xarb H Tablet

Xarb H Tablet is a combination prescription medicine used to treat high blood pressure (hypertension). It is typically prescribed when a single medicine is not sufficient to control your blood pressure. By lowering high blood pressure, this medication helps protect your vital organs and reduces the risk of life-threatening events like strokes and heart attacks.

To get the best results, you must take Xarb H Tablet consistently every day, exactly as prescribed by your doctor. It can be taken with or without food, but taking it at the same time each day helps keep a steady amount of medicine in your body. Combining this medication with a low-salt diet and regular exercise will greatly support your treatment.

While taking this medicine, you might experience mild side effects such as lightheadedness or feeling tired as your body adjusts. However, if you notice severe muscle weakness, extreme thirst, or signs of an allergic reaction, you should contact your doctor immediately. Regular check-ups help ensure the medicine is working safely for you.

Before starting Xarb H Tablet , tell your doctor if you have a history of kidney disease, liver damage, diabetes, or gout. Do not take this medicine if you are pregnant, as it can cause serious harm to an unborn baby. It should also be avoided by individuals who cannot pass urine or those with severe allergies to sulfur-based medications.

This medicine can interact with alcohol, which may cause a sudden drop in blood pressure and make you feel dizzy. It is highly recommended to consult your doctor if you are breastfeeding or are an elderly individual, as you may require closer monitoring. Let your healthcare provider know about all other medications you take to avoid harmful interactions.

Uses of Xarb H Tablet

Xarb H Tablet is used to manage high blood pressure and reduce the risk of complications associated with uncontrolled hypertension. Its uses include:

  • High blood pressure (hypertension): Xarb H Tablet helps by combining two different mechanisms to relax your blood vessels and remove excess fluid, making it easier for your heart to pump blood.
  • Reduction of cardiovascular risks: By maintaining normal blood pressure levels, this medication directly helps prevent severe complications such as strokes, heart attacks, and kidney failure.

Key Benefits

Xarb H Tablet combines two complementary blood pressure-lowering medicines to provide effective and sustained control of hypertension. Its benefits include:

  • Dual-Action Control: By combining two active ingredients in one tablet, Xarb H Tablet lowers blood pressure more effectively than either ingredient alone. This reduces the number of daily pills you need to take to keep your blood pressure in a safe range.
  • Long-Term Organ Protection: Consistently managing your blood pressure protects vital organs over time. It lowers the physical strain on your blood vessels, which helps keep your heart, brain, and kidneys healthy.
  • Convenient Daily Routine: The once-daily dosing structure makes it easier to stay consistent with your treatment, helping you maintain steady blood pressure levels throughout the day and night.

Directions for Use

  • Xarb H Tablet can be taken with or without food as advised by your doctor.
  • Follow your doctor’s instructions on the dosage and timing of this medication.
  • Swallow Xarb H Tablet as a whole with a glass of water.
  • Do not crush, break, or chew it.

How Xarb H Tablet Works

Xarb H Tablet contains irbesartan and hydrochlorothiazide, which work together to lower blood pressure in different ways. The first active ingredient, irbesartan, is a blood vessel relaxer (an angiotensin receptor blocker). It works by blocking a natural substance in your body that causes blood vessels to tighten and narrow. When this substance is blocked, your blood vessels can relax and widen, allowing blood to flow more easily. The second active ingredient, hydrochlorothiazide, is a water pill (a thiazide diuretic). It prompts your kidneys to filter out extra water and salt from your bloodstream and release it through your urine. Reducing the total amount of fluid in your body lowers the pressure inside your blood vessels. Together, these two ingredients work in harmony: one widens the blood vessels while the other reduces the volume of fluid flowing through them. This dual action provides highly effective blood pressure control.
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Alcohol

Unsafe

You are recommended not to consume alcohol and Xarb H Tablet to avoid unpleasant side effects like drowsiness, dizziness, and liver damage.

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Pregnancy

Unsafe

Xarb H Tablet is not recommended during pregnancy as it is a category D pregnancy drug. This medicine may cause fetal damage and can affect the unborn baby (fetus).

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Breast Feeding

Caution

Xarb H Tablet is known to pass breast milk, but its effect on the baby is not known. So, before breastfeeding, let your doctor know about this.

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Driving

Caution

Drive with caution, Xarb H Tablet usually causes drowsiness and affects driving ability.

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Liver

Caution

Xarb H Tablet to be taken with caution, especially if you have had a history of liver disease. Your doctor will have to change the dosage depending on your medical condition and your reaction to treatment.

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Kidney

Caution

Xarb H Tablet to be taken with caution, especially if you have had a history of kidney disease. Your doctor will have to change the dosage depending on your medical condition and your reaction to treatment.

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Children

Unsafe

Efficacy and safety of Xarb H Tablet have not been established in children. So, Xarb H Tablet should not be given to children under 18 years of age.

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Heart

Safe if prescribed

Xarb H Tablet is safe for use in heart patients if recommended by the physician.

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Geriatrics

Caution

Xarb H Tablet should be used under caution in geriatric patients. Please consult your physician.

What if I have taken an overdose of Xarb H Tablet

If you take too much of this medication, you may experience severe dizziness, fainting, or a rapid heartbeat. Seek immediate emergency medical attention or contact your local poison control centre right away.

Diet & Lifestyle Advise

  • Limit your salt intake: High amounts of sodium make your body hold onto water, which raises blood pressure and works against this medication. Focus on a low-salt diet.
  • Stay safely hydrated: Because this medicine increases urination, drink an adequate amount of water daily. However, do not suddenly increase your fluid intake dramatically without speaking to your doctor.
  • Avoid salt substitutes containing potassium: One of the components in Xarb H Tablet can raise potassium levels in your blood. Using potassium-rich salt substitutes can lead to dangerously high potassium levels.
  • Limit alcohol consumption: Drinking alcohol while taking this medicine can cause your blood pressure to drop too low, leading to severe dizziness or fainting.
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How Soon It Starts Working

The time required for Xarb H Tablet to start to work: The effect of Xarb H Tablet is observed within 2 hours of administration. The time for which the effects of Xarb H Tablet last: Xarb H Tablet effect lasts for 24 hours.

What if you forget to take Xarb H Tablet

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and resume your regular schedule. Do not take a double dose to make up for a missed one.

Storage

•Store Xarb H Tablet at room temperature between 20°C and 25°C (68°F to 77°F). •Keep the tablets in their original packaging to protect them from moisture and light. Avoid storing them in the bathroom cabinet.

Drug Warnings

  • Get up slowly: To avoid dizziness or fainting when moving from a sitting or lying position, stand up gradually and steady yourself for a moment.
  • Protect your skin from the sun: This medicine can make your skin highly sensitive to sunlight. Wear protective clothing, hats, and apply broad-spectrum sunscreen when outdoors.
  • Monitor your blood pressure: Keep a home log of your blood pressure readings to share with your doctor during check-ups.
  • Schedule regular blood tests: Your doctor will need to monitor your kidney function and check your blood mineral levels (like potassium and sodium) regularly.
  • Avoid self-medicating for pain: Consult your pharmacist before taking pain relievers like ibuprofen or naproxen, as they can put extra strain on your kidneys and raise your blood pressure.

Drug-Drug Interactions

verifiedApollotooltip

Inform your doctor if you are taking any of the following medicines, as they may interact with Xarb H Tablet :

  • Potassium Supplements or Potassium-Sparing Diuretics: These may increase the risk of high potassium levels in the blood.
  • Lithium: Xarb H Tablet may increase lithium levels in the blood and raise the risk of lithium toxicity.
  • Nonsteroidal Anti-Inflammatory Drugs (NSAIDs): Medicines such as ibuprofen or naproxen may reduce the blood-pressure-lowering effect of this medicine and increase the risk of kidney problems.
  • Other Blood Pressure Medicines: Taking multiple blood pressure-lowering medicines together may cause excessive lowering of blood pressure, leading to dizziness or fainting.
Irbesartan + HydrochlorothiazideCisapride
Critical
Irbesartan + HydrochlorothiazideDofetilide
Critical

Drug-Drug Interactions

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Irbesartan + HydrochlorothiazideCisapride
Critical
How does the drug interact with Xarb H Tablet:
Taking Cisapride and Hydrochlorothiazide can increase the risk of an irregular heart rhythm which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Combining Cisapride and Hydrochlorothiazide together is generally avoided as it can result in an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, or fast or pounding heartbeats, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
Irbesartan + HydrochlorothiazideDofetilide
Critical
How does the drug interact with Xarb H Tablet:
Taking Dofetilide and Hydrochlorothiazide can increase the risk of an irregular heart rhythm which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Combining Dofetilide and Hydrochlorothiazide together is not recommended as it can result in an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Irbesartan + HydrochlorothiazideArsenic trioxide
Severe
How does the drug interact with Xarb H Tablet:
Co-administration of Arsenic trioxide and Hydrochlorothiazide can increase the risk of an irregular heart rhythm which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Arsenic trioxide and Hydrochlorothiazide can result in an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, fast heartbeats, weakness, tiredness, drowsiness, confusion, muscle pain, cramps, nausea, or vomiting. consult the doctor immediately. Do not stop using any medications without a doctor's advice.
Irbesartan + HydrochlorothiazideMoexipril
Severe
How does the drug interact with Xarb H Tablet:
Taking Irbesartan with Moexipril may increase the risk of side effects (low blood pressure, kidney function impairment, and increased potassium levels in the blood).

How to manage the interaction:
Although taking Irbesartan with Moexipril together can result in an interaction, it can be taken if a doctor has prescribed it. However, consult a doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, or a slow or irregular heartbeat. Do not discontinue any medications without a doctor's advice.
Irbesartan + HydrochlorothiazideTrimethoprim
Severe
How does the drug interact with Xarb H Tablet:
Taking Irbesartan with Trimethoprim may increase potassium levels in the blood. High levels of potassium can develop into a condition known as hyperkalemia- high potassium levels.

How to manage the interaction:
Although taking Irbesartan with Trimethoprim together can result in an interaction, it can be taken if a doctor has prescribed it. However, consult your doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, or a slow or irregular heartbeat. Do not discontinue any medications without a doctor's advice.
Irbesartan + HydrochlorothiazideBenazepril
Severe
How does the drug interact with Xarb H Tablet:
Taking Irbesartan with Benazepril may increase the risk of side effects (low blood pressure, kidney function impairment, and increased potassium levels in the blood0.

How to manage the interaction:
Although taking Irbesartan and Benazepril together can result in an interaction, it can be taken if a doctor has prescribed it. However, consult a doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, or a slow or irregular heartbeat. Do not discontinue any medications without a doctor's advice.
Irbesartan + Hydrochlorothiazidepotassium phosphate
Severe
How does the drug interact with Xarb H Tablet:
Taking Irbesartan with Potassium phosphate may increase potassium levels in the blood. High potassium levels can cause hyperkalemia, which can lead to kidney failure, muscular paralysis and heart problems.

How to manage the interaction:
Although taking Irbesartan with potassium phosphate together can result in an interaction, it can be taken if a doctor has prescribed it. However, consult a doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, slow or irregular heartbeat. Do not discontinue any medications without a doctor's advice.
Irbesartan + HydrochlorothiazideTriamterene
Severe
How does the drug interact with Xarb H Tablet:
Taking Irbesartan with Triamterene may increase potassium levels in the blood. High potassium levels can cause hyperkalemia, which can lead to kidney failure, muscular paralysis and heart problems.

How to manage the interaction:
Although taking Irbesartan with Triamterene together can result in an interaction, it can be taken if a doctor has prescribed it. However, consult a doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, or a slow or irregular heartbeat. Do not discontinue any medications without a doctor's advice.
Irbesartan + HydrochlorothiazidePotassium chloride
Severe
How does the drug interact with Xarb H Tablet:
Taking Irbesartan with Potassium chloride may increase potassium levels in the blood.

How to manage the interaction:
Although taking Irbesartan with Potassium chloride together can result in an interaction, it can be taken if a doctor has prescribed it. However, consult the doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, or a slow or irregular heartbeat. Do not discontinue any medications without a doctor's advice.
Irbesartan + HydrochlorothiazideAmiodarone
Severe
How does the drug interact with Xarb H Tablet:
Coadministration of Amiodarone together with Hydrochlorothiazide may raise the risk of an abnormal heart rhythm.

How to manage the interaction:
Even though Amiodarone and Hydrochlorothiazide interact, they can be used if prescribed by a doctor. If you have cardiac problems or electrolyte imbalances, you may be at greater risk. If you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, Weakness, tiredness, drowsiness, confusion, painful muscle cramping, dizziness, nausea, or vomiting, get medical attention. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip

Certain foods and drinks may interact with Xarb H Tablet or worsen its side effects:

  • Potassium-Containing Salt Substitutes: Avoid using salt substitutes containing potassium unless advised by your doctor, as they may increase blood potassium levels.
  • Alcohol: Alcohol may increase dizziness, drowsiness, and the risk of excessively low blood pressure.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[ANTI- HYPERTENSIVES]

FAQs

Xarb H Tablet is used to treat high blood pressure (hypertension).
Xarb H Tablet is a combination of two medicines, namely: Irbesartan and Hydrochlorothiazide. Irbesartan is an angiotensin receptor blocker (ARB) that blocks the hormone angiotensin and relaxes blood vessels. This allows the blood to flow more smoothly in the blood vessels, and the heart can pump more efficiently. Hydrochlorothiazide (diuretic or water pill), removes extra water and certain electrolytes from the body. Together, both lower fluid overload, blood pressure, improves blood flow, and reduce the future risk of a heart attack.
Yes, Xarb H Tablet can cause dizziness. It is advised to avoid driving or operate any heavy machinery while taking Xarb H Tablet . In case you feel dizzy or lightheaded, it is advised to rest for some time until you feel better.
It's unlikely that Xarb H Tablet affects fertility in men or women. However, in some cases, some water pills like hydrochlorothiazide may lead to erectile dysfunction. For the best advice, please consult your doctor.
In case you have missed a dose of Xarb H Tablet , you are advised to take it as soon as you remember. However, try not to miss a dose in the first place, if it's time for you to take your next dose, then do not take both the doses together. Take only one dose; taking a double dose of Xarb H Tablet will lead to low blood pressure.
No, you are advised to inform your doctor and monitor your blood pressure for at least two weeks before stopping the medicine. Depending upon your current blood pressure readings, there is a possibility your doctor may lower your medicine dosage and not recommend discontinuing it.
Please inform your doctor before surgery if you are taking Xarb H Tablet . It needs to be stopped because it might lower the blood pressure further if taken along with certain local anaesthetic medication.
No, you should not take Xarb H Tablet if you are pregnant. Taking this medication during pregnancy can cause serious injury or death to the unborn baby. If you plan to become pregnant or suspect you are pregnant, stop the medicine immediately and talk to your doctor.
Yes, because one of the active ingredients is a mild water pill (diuretic), you will likely need to urinate more frequently, especially when you first start taking it. To prevent waking up during the night, it is best to take this medicine in the morning. Talk to your doctor if this becomes highly bothersome.
Muscle cramps, weakness, or spasms can be a sign that your blood mineral levels (like potassium or sodium) have dropped. If you experience these symptoms, contact your clinic right away so they can check your blood levels. Talk to your doctor.
It is highly recommended to limit or avoid alcohol while taking this medicine. Alcohol can increase the risk of side effects like dizziness, lightheadedness, and fainting by causing your blood pressure to drop too low. Talk to your doctor about safe alcohol limits.
Yes, one of the active ingredients can make your skin more sensitive to sunlight, which increases your risk of severe sunburns. Make sure to apply sunscreen, wear protective clothing, and avoid tanning beds. Talk to your doctor if you experience unusual skin rashes or sunburns.
You should avoid taking common pain relievers known as NSAIDs (such as ibuprofen or naproxen) without consulting a professional. These pain relievers can interfere with how well Xarb H Tablet lowers your blood pressure and can also increase the risk of kidney damage. Talk to your doctor for safer pain-relief alternatives.

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Country of origin

India

Manufacturer/Marketer address

401, LSC, C-Block, Mohan Place Saraswati Vihar Delhi DL 110034 In
Other Info - XAR0003
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