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  3. VYFAT 60MG TABLET

VYFAT 60MG TABLET, Pack of 10 TABLETS
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Written By Veda Maddala , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy

VYFAT 60MG TABLET is used to treat obesity and help in weight loss. It is to be used along with a low-calorie diet and regular physical exercise. It contains Orlistat, which decreases the absorption of fat from the food you eat. Thus, fat passes through the gut and is excreted in the faeces, which makes the body unable to use fat as a source of energy or convert it into fat tissue. Thus, it helps in weight loss.

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Composition :

ORLISTAT-60MG

Manufacturer/Marketer :

Intas Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About VYFAT 60MG TABLET

VYFAT 60MG TABLET is used to treat obesity and help in weight loss. VYFAT 60MG TABLET is to be used along with a low-calorie diet and regular physical exercise. Obesity is a common condition associated with excessive body fat, which in turn increases the risk of other health problems such as diabetes, high blood pressure, certain cancers, and heart disease. Intake of more calories than you burn by exercise or daily activities results in obesity.

VYFAT 60MG TABLET contains Orlistat, which works in the small intestine and stomach and prevents the action of enzymes that break down fat, which is absorbed by the body. VYFAT 60MG TABLET decreases the absorption of fat from the food you eat. Thus, fat passes through the gut and is excreted in the faeces, which makes the body unable to use fat as a source of energy or convert it into fat tissue. Thereby, VYFAT 60MG TABLET helps in weight loss.

Take VYFAT 60MG TABLET as prescribed by your doctor. You are advised to take VYFAT 60MG TABLET for as long as your doctor has prescribed it for you based on your medical condition. Some people may experience soft stools, sudden bowel motions, flatulence (gas) with or without oily spotting, oily or fatty stools, stomach pain, stool incontinence (involuntary leakage of stools), and runny or liquid stools. Most of these side effects of VYFAT 60MG TABLET do not require medical attention and gradually resolve over time. However, if the side effects persist, please consult your doctor.

If you are allergic to VYFAT 60MG TABLET or any other medicines, please tell your doctor. Avoid taking VYFAT 60MG TABLET if you are pregnant or planning for pregnancy, as it may cause fetal harm. It is not known whether VYFAT 60MG TABLET is excreted in human milk. Therefore, please consult a doctor if you are a breastfeeding woman. VYFAT 60MG TABLET is not recommended for children below 18 years of age, as the safety and effectiveness have not been established. You are advised to take a multivitamin containing fat-soluble vitamins such as A, D, E, and K at bedtime, as VYFAT 60MG TABLET may reduce the absorption of certain vitamins in the body.

Uses of VYFAT 60MG TABLET

VYFAT 60MG TABLET is used in the management of obesity. The detailed uses of VYFAT 60MG TABLET are as follows:

  • Manages Obesity: VYFAT 60MG TABLET is used along with a low-calorie diet to promote weight loss in obese or overweight individuals by decreasing the absorption of fat from food and preventing excess fat accumulation in the body.
  • Prevents Weight Regain: VYFAT 60MG TABLET supports long-term weight management by lowering the risk of regaining lost weight after initial weight loss.

Directions for Use

  • VYFAT 60MG TABLET can be taken during, or up to 1 hour after meals, as advised by your doctor.
  • Take VYFAT 60MG TABLET daily at the same time for effective results or as your doctor advises.
  • Swallow VYFAT 60MG TABLET as a whole with a glass of water.
  • Do not crush, chew, or break it.

Medicinal Benefits

  • VYFAT 60MG TABLET contains Orlistat, an anti-obesity medicine used to aid weight management in overweight and obese patients.
  • Blocks fat absorption: Acts in the stomach and small intestine to inhibit enzymes (lipases) responsible for breaking down dietary fat.
  • Reduces calorie intake from fat: Prevents the absorption of about 25–30% of the fat consumed in meals, allowing it to pass through the gut and be excreted.
  • Promotes safe weight loss: Helps achieve gradual weight reduction when combined with a calorie-controlled diet and regular physical activity.
  • Lowers obesity-related health risks: Reduces the risk of developing type 2 diabetes, high blood pressure, heart disease, and other weight-related conditions.
  • Supports long-term weight management: Helps maintain weight loss over time when used alongside lifestyle modifications under medical supervision.

How VYFAT 60MG TABLET Works

VYFAT 60MG TABLET contains Orlistat, which works in the small intestine and stomach and prevents the action of enzymes that break down fat, which is absorbed by the body. VYFAT 60MG TABLET decreases the absorption of fat from the food you eat. Thus, fat passes through the gut and is excreted in the faeces, which makes the body unable to use fat as a source of energy or convert it into fat tissue. Thereby, VYFAT 60MG TABLET helps in weight loss.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Vyfat 60mg Tablet
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
Here are the steps to manage the medication-triggered Upper respiratory tract infection:
  • Inform your doctor about the symptoms you're experiencing due to medication.
  • Your doctor may adjust your treatment plan, which could include changing your medication, adding new medications, or offering advice on managing your symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Stay hydrated by drinking plenty of fluids to help loosen and clear mucus from your nose, throat, and airways.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your symptoms don't subside or worsen, consult your doctor for further guidance.
  • Please inform your doctor about joint swelling, as they may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Maintain a healthy lifestyle is key to relieving joint discomfort. Regular exercise, such as low-impact sports like walking, cycling, or swimming, should be combined with a well-balanced diet.
  • Aim for 7-8 hours of sleep per night to assist your body in repairing and rebuilding tissue.
  • Whenever there is swelling, apply heat or cold packs to the affected joint that can help reduce pain and inflammation.
  • Track when joint pain occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.

What if I have taken an overdose of VYFAT 60MG TABLET

Avoid taking extra doses, as doing so can lead to unwanted side effects. If an overdose is suspected, seek prompt medical assistance or contact the nearest poison control centre, even if you feel well.

Drug Warnings

  • Inform your doctor if you are allergic to VYFAT 60MG TABLET or any other medicines.
  • Consult your doctor before taking VYFAT 60MG TABLET if you have cholestasis (blocked bile flow from the liver), chronic malabsorption syndrome, anorexia, bulimia, thyroid disorder, diabetes, kidney problems, or liver problems.
  • Avoid taking VYFAT 60MG TABLET if you are pregnant or planning to become pregnant, as it may cause harm to the unborn baby.
  • If you are breastfeeding, consult your doctor before using VYFAT 60MG TABLET, as it is not known whether the medicine passes into breast milk.
  • VYFAT 60MG TABLET is not recommended for children under 18 years of age due to a lack of established safety and effectiveness.
  • Combine VYFAT 60MG TABLET with regular exercise and a low-fat, low-calorie diet for best results in weight management.
  • If you experience severe diarrhoea while taking VYFAT 60MG TABLET, it may reduce the effectiveness of oral contraceptive pills. Use an additional contraceptive method to prevent pregnancy in such cases.
  • Take a daily multivitamin supplement containing fat-soluble vitamins (A, D, E, and K) at bedtime, at least 2 hours after VYFAT 60MG TABLET, since the medicine may reduce the absorption of these vitamins.

Drug-Drug Interactions

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OrlistatMipomersen
Severe
OrlistatLeflunomide
Severe

Drug-Drug Interactions

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OrlistatMipomersen
Severe
How does the drug interact with Vyfat 60mg Tablet:
Co-administration of Mipomersen and Vyfat 60mg Tablet can increase the risk of developing liver problems.

How to manage the interaction:
Co-administration of Mipomersen and Vyfat 60mg Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like fever, chills, joint pain, unusual bleeding, skin rash, loss of appetite, fatigue, vomiting, abdominal pain, dark-coloured urine, light-coloured stools, and/or yellowing of the skin or eyes, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
OrlistatLeflunomide
Severe
How does the drug interact with Vyfat 60mg Tablet:
Co-administration of leflunomide and Vyfat 60mg Tablet can increase the risk of liver problems.

How to manage the interaction:
Co-administration of Leflunomide and Vyfat 60mg Tablet can lead to an interaction, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
OrlistatCalcitriol
Severe
How does the drug interact with Vyfat 60mg Tablet:
Co-administration of Vyfat 60mg Tablet with Calcitriol may reduce the levels of Calcitriol which can lead to low treatment outcomes.

How to manage the interaction:
Although there is an interaction, Calcitriol can be taken with Vyfat 60mg Tablet when prescribed by the doctor. Do not discontinue any medications without consulting a doctor.
OrlistatLomitapide
Severe
How does the drug interact with Vyfat 60mg Tablet:
Co-administration of Lomitapide and Vyfat 60mg Tablet can increase the risk of developing liver problems.

How to manage the interaction:
Co-administration of Lomitapide and Vyfat 60mg Tablet can lead to an interaction, it can be taken when advised by your doctor. However, if you experience any symptoms like fever, chills, joint pain or swelling, unusual bleeding, skin rash, itching, loss of appetite, fatigue, vomiting, abdominal pain, dark-coloured urine, light-coloured stools, and/or yellowing of the skin or eyes, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
OrlistatKetoconazole
Severe
How does the drug interact with Vyfat 60mg Tablet:
Coadministration of Ketoconazole and Vyfat 60mg Tablet can increase the risk of developing liver damage.

How to manage the interaction:
Although taking Ketoconazole and Vyfat 60mg Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience fever, chills, joint pain, unusual bleeding, skin rash, lack of appetite, vomiting, abdominal pain, dark urine, or yellowing of the skin or eyes, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
OrlistatCiclosporin
Severe
How does the drug interact with Vyfat 60mg Tablet:
Coadministration of Ciclosporin with Vyfat 60mg Tablet can reduce the levels and effects of Ciclosporin.

How to manage the interaction:
Although there is a possible interaction between Vyfat 60mg Tablet and Ciclosporin, you can take these medicines together when prescribed by your doctor. Do not stop using any medications without talking to a doctor.
OrlistatTeriflunomide
Severe
How does the drug interact with Vyfat 60mg Tablet:
Co-administration of Teriflunomide and nintedanib can increase the risk of developing liver problems.

How to manage the interaction:
Co-administration of Teriflunomide and Nintedanib can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like fever, chills, joint pain, unusual bleeding, skin rash, loss of appetite, fatigue, vomiting, abdominal pain, dark-colored urine, light-colored stools, and/or yellowing of the skin or eyes, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Follow a low-fat, balanced diet where no more than 30% of calories come from fat to minimise side effects like oily stools. Choose lean meats, fish, low-fat dairy, whole grains, vegetables, and fruits.
  • Distribute fat intake evenly throughout the day to avoid digestive discomfort caused by excessive fat intake in a single meal.
  • Avoid high-fat, fried, or greasy foods, as these can increase gastrointestinal side effects while taking VYFAT 60MG TABLET.
  • Take a multivitamin supplement at bedtime, at least two hours apart from VYFAT 60MG TABLET, since the medicine may reduce the absorption of vitamins A, D, E, and K.
  • Stay hydrated by drinking sufficient water throughout the day to support digestion and prevent constipation.
  • Engage in regular physical activity, aiming for at least 150 minutes of moderate exercise per week to aid weight loss and improve overall health.
  • Limit or avoid alcohol intake as it adds extra calories and may slow down your weight-loss progress.
  • Monitor your weight and overall health regularly and follow up with your doctor to track treatment effectiveness.
  • Eat small, frequent meals to help control hunger and maintain stable energy levels.
  • Take VYFAT 60MG TABLET as advised by the doctor, and do not skip, double, or change your dose without medical advice.

Habit Forming

No

Therapeutic Class

ANTIOBESITY DRUG

VYFAT 60MG TABLET Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Caution

Alcohol should be limited or avoided while taking Orlistat to support weight loss goals and overall health.

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Pregnancy

Unsafe

VYFAT 60MG TABLET is a Category X pregnancy drug and is considered unsafe for pregnant women as it may cause harm to the unborn baby. So, if you are pregnant or planning for pregnancy, please inform your doctor before taking VYFAT 60MG TABLET.

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Breast Feeding

Caution

It is unknown whether VYFAT 60MG TABLET is excreted in human milk. Therefore, it is given to breastfeeding mothers only if the doctor thinks the benefits outweigh the risks.

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Driving

Safe if prescribed

VYFAT 60MG TABLET usually does not affect your ability to drive or operate machinery.

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Liver

Caution

Take VYFAT 60MG TABLET with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take VYFAT 60MG TABLET with caution, especially if you have a history of Kidney diseases/conditions. VYFAT 60MG TABLET may cause kidney stones in patients suffering from chronic kidney disease. Please consult a doctor if you have kidney problems so that the dose may be adjusted by your doctor as required.

bannner image

Children

Unsafe

VYFAT 60MG TABLET is not recommended for children below 18 years of age, as the safety and effectiveness have not been established.

Have a query?

FAQs

VYFAT 60MG TABLET is used to treat obesity and help in weight loss. It is to be used along with a low-calorie diet and regular physical exercise.

VYFAT 60MG TABLET contains Orlistat, which works in the small intestine and stomach and inhibits the action of enzymes that break down fat, which is absorbed by the body. VYFAT 60MG TABLET decreases the absorption of fat from the food you eat. Thus, fat passes through the gut and is excreted in the faeces, which makes the body unable to use fat as a source of energy or convert it into fat tissue. Thereby, VYFAT 60MG TABLET helps in weight loss.

You are not recommended to take VYFAT 60MG TABLET with ciclosporin (used for organ transplant rejections, severe rheumatoid arthritis) as it may reduce the effectiveness of ciclosporin. However, if you are supposed to take both medicines, you are advised to take ciclosporin after 3 hours of taking VYFAT 60MG TABLET. However, please consult a doctor before taking VYFAT 60MG TABLET with any other medicines.

VYFAT 60MG TABLET may cause kidney stones in patients suffering from chronic kidney disease. Therefore, if you have any kidney problems, please inform your doctor before taking VYFAT 60MG TABLET.

VYFAT 60MG TABLET should be used with caution in diabetic patients as it may increase the risk of low blood sugar levels. Therefore, inform your doctor if you have diabetes before taking VYFAT 60MG TABLET so that the dose of antidiabetic medicine may be adjusted accordingly.

You are recommended to avoid high-fat meals that include butter, meat, dark chocolate, olive oil, nuts and seeds (brazil nuts) with VYFAT 60MG TABLET as it may increase the risk of adverse effects on the stomach or intestines.

You are recommended to use VYFAT 60MG TABLET for as long as your doctor has prescribed it. However, avoid taking VYFAT 60MG TABLET for more than 6 months. If you do not notice weight loss after taking VYFAT 60MG TABLET for 12 weeks, please consult a doctor.

You are recommended to take a multivitamin containing fat-soluble vitamins such as A, D, E and K at bedtime or at least 2 hours after taking VYFAT 60MG TABLET. Generally, VYFAT 60MG TABLET may reduce the absorption of certain vitamins in the body. Therefore, your doctor may advise you to take multivitamins.

Do not take VYFAT 60MG TABLET if you are allergic to any of its components or if you have cholestasis (bile flow from the liver is blocked) or chronic malabsorption syndrome.

Follow a low-calorie diet and regular physical exercise. Include fruits, vegetables and whole grains in your diet.

Interaction of VYFAT 60MG TABLET with alcohol is unknown. Please consult a doctor before consuming alcohol while using VYFAT 60MG TABLET.

VYFAT 60MG TABLET starts working within 2 weeks and you may notice results in 1-3 months.

Yes, it is important to do regular exercise and maintain a low-fat and low-calorie diet along with VYFAT 60MG TABLET for effective results.

VYFAT 60MG TABLET should be swallowed as a whole with water; do not crush or chew it. Take it during a meal or up to 1 hour after a meal.

VYFAT 60MG TABLET may cause side effects like soft stools, sudden bowel motions, flatulence (gas) with or without oily spotting, oily or fatty stools, stomach pain, stool incontinence (involuntary leakage of stools), and runny or liquid stools. If the side effects persist, please consult your doctor.

Country of origin

India

Manufacturer/Marketer address

Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.
Other Info - VYF0002

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Author Details

Veda MaddalaDoctor badge

Written By

Veda Maddala

M Pharmacy

Bayyarapu Mahesh KumarDoctor badge

Reviewed By

Bayyarapu Mahesh Kumar

M Pharmacy

Last Updated

Aug 8, 2025 | 1:53 PM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.medicines.org.uk/emc/files/pil.6533.pdf
  2. https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/020766s029lbl.pdf

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