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compositionComposition:PEMETREXED-10MG/ML
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Vrtu 100 mg Injection 10 ml is used to treat Non-small cell lung cancer and malignant pleural mesothelioma. It contains Pemetrexed, which treats cancer by blocking the action of substances that may help the cancer cells multiply. Do not use this medication if you are pregnant or breastfeeding. Women and men should use effective contraception during treatment with Vrtu 100 mg Injection 10 ml and for 6 and 3 months afterwards. It is not recommended for children below 18 years.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

PEMETREXED-10MG/ML

Manufacturer/Marketer :

Epic Bioscience Pvt Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-28

Return Policy :

Not Returnable

About Vrtu 100 mg Injection 10 ml

Vrtu 100 mg Injection 10 ml is an injection used to treat certain types of cancers, such as non-small cell lung cancer and malignant pleural mesothelioma. It is a medical treatment designed to slow down or stop the growth of cancer cells in the body. By targeting these abnormal cells, the medicine helps manage the disease and prevent it from spreading further.

This medicine is given as an infusion into a vein on a schedule determined by your doctor, usually once every three weeks. Because it is given in a clinical setting by healthcare professionals, maintaining your scheduled appointments is vital for consistent results. Staying well-hydrated and eating balanced, small meals during your treatment cycle can support your body through therapy.

Common side effects of this treatment include fatigue, nausea, and low blood cell counts. You must contact your doctor immediately if you develop signs of an infection, such as a fever, or experience unusual bleeding and bruising. Your healthcare team will monitor your blood counts regularly to ensure it is safe for you to continue treatment.

Before you begin taking Vrtu 100 mg Injection 10 ml, tell your doctor if you have kidney disease, as this condition can affect how your body clears the medicine. Do not take this if you have had a severe allergic reaction to this medicine or any of its ingredients. It is also important to share your complete medical history with your oncologist before your first session.

Certain medicines, such as nonsteroidal anti-inflammatory drugs (NSAIDs), can interact with Vrtu 100 mg Injection 10 ml and increase your risk of severe side effects. Avoid alcohol and smoking during treatment, as they can place extra strain on your liver and worsen fatigue. If you are pregnant, planning to become pregnant, or breastfeeding, you should not take this medicine, and elderly patients may require closer monitoring of their kidney function.

Uses of Vrtu 100 mg Injection 10 ml

Vrtu 100 mg Injection 10 ml is used to treat certain types of cancers. The detailed uses of Vrtu 100 mg Injection 10 ml are as follows:

  • Non-small cell lung cancer: Vrtu 100 mg Injection 10 ml helps by stopping the division and growth of cancer cells in patients with advanced non-squamous non-small cell lung cancer.
  • Malignant pleural mesothelioma: Vrtu 100 mg Injection 10 ml is used in combination with other chemotherapy drugs to treat this rare cancer of the lung lining, helping to control tumour growth.

Key Benefits

Vrtu 100 mg Injection 10 ml helps treat certain types of cancer by slowing the growth and spread of cancer cells. With regular use as prescribed, it helps control disease progression, relieve tumour-related symptoms, and support long-term treatment outcomes.

  • Helps Control Cancer Progression: By slowing the growth or stabilising tumours, this medicine helps manage the disease and delay its progression.
  • Relieves Cancer-Related Symptoms: As tumour growth is controlled, this medicine may help reduce persistent coughing, chest pain, breathing difficulties, and other symptoms caused by cancer, improving daily comfort.
  • Supports Long-Term Disease Management: When used as maintenance therapy after initial treatment, this medicine helps delay the return of cancer, prolong disease control, and support better quality of life and overall treatment outcomes.

Directions for Use

  • Follow your doctor’s instructions on the dosage and timing of this medication.
  • Vrtu 100 mg Injection 10 ml will be administered by a nurse or doctor.
  • Do not self-administer.

How Vrtu 100 mg Injection 10 ml Works

Vrtu 100 mg Injection 10 ml contains pemetrexed, which is a folate antimetabolite that works by disrupting the replication process of cancer cells. Cancer cells require certain natural substances, including folate, to synthesise DNA and RNA so they can grow and divide. This medicine acts as an impostor, blocking the specific enzymes that use folate to build genetic material. Without the necessary building blocks for DNA, the cancer cells are unable to replicate and eventually die. Because cancer cells divide much faster than most healthy cells, they are highly sensitive to this blockage, which helps limit the spread of the disease throughout your body.
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Alcohol

Consult your doctor

It is not known if alcohol affects Vrtu 100 mg Injection 10 ml. Please consult your doctor.

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Pregnancy

Unsafe

Pemetrexed belongs to pregnancy category D. The use of Vrtu 100 mg Injection 10 ml should be avoided during pregnancy as it might harm the unborn baby.

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Breast Feeding

Unsafe

Breastfeeding must be discontinued during treatment with Vrtu 100 mg Injection 10 ml.

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Driving

Caution

Vrtu 100 mg Injection 10 ml may cause tiredness. Caution is advised while driving or operating heavy machinery.

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Liver

Consult your doctor

If you have a history of liver disease, inform your doctor before receiving Vrtu 100 mg Injection 10 ml.

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Kidney

Caution

Dose adjustment may be needed. If you have a history of kidney disease, inform your doctor before receiving Vrtu 100 mg Injection 10 ml.

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Children

Unsafe

Vrtu 100 mg Injection 10 ml is not recommended for children below 18 years as safety and effectiveness have not been established.

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Heart

Consult your doctor

Please consult your doctor if you have any heart problems before taking Vrtu 100 mg Injection 10 ml.

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Geriatrics

Consult your doctor

Please consult a doctor before administering Vrtu 100 mg Injection 10 ml to geriatric patients. Your doctor will prescribe Vrtu 100 mg Injection 10 ml if the benefits outweigh the risks.

What if I have taken an overdose of Vrtu 100 mg Injection 10 ml

An overdose is highly unlikely because a trained medical professional prepares and injects your dose. However, if you suspect an error or experience severe symptoms after your session, seek immediate medical attention.

Diet & Lifestyle Advise

  • Take your prescribed supplements: Always take your folic acid and vitamin B12 supplements exactly as directed to help protect your healthy blood cells from the medicine.
  • Stay well-hydrated: Drink plenty of water and clear fluids, especially on the days surrounding your treatment, to help support your kidney function.
  • Eat small, frequent meals: If you experience nausea or a loss of appetite, eating smaller portions five to six times a day can help maintain your nutrition.
  • Avoid infections: Wash your hands frequently, practice good personal hygiene, and avoid close contact with anyone who is currently sick.
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Have a query?

How Soon It Starts Working

The time required for Vrtu 100 mg Injection 10 ml to start to work: The time required for Vrtu 100 mg Injection 10 ml to show its action is not clinically established. The time for which the effects of Vrtu 100 mg Injection 10 ml last: The effect of Vrtu 100 mg Injection 10 ml lasts for 6 to 9 hours.

What if you forget to take Vrtu 100 mg Injection 10 ml

Since this medicine is given by a healthcare professional at scheduled clinical visits, missing a dose is unlikely. If you miss an appointment, contact your clinic immediately to reschedule your infusion.

Storage

• Unopened vials of Vrtu 100 mg Injection 10 ml dry powder should be stored at room temperature, between 20°C to 25°C (68°F to 77°F).

Drug Warnings

  • Check the solution: If you observe your treatment being prepared, ensure the liquid is clear, colourless to light yellow, and free of visible particles before it is injected.
  • Monitor your temperature: Keep a reliable digital thermometer at home and check your temperature immediately if you feel warm, cold, or unwell.
  • Avoid certain pain relievers: Do not take ibuprofen, naproxen, or other NSAIDs for a few days before and after your infusion without consulting your doctor first, as they can increase the medicine's toxicity.
  • Protect your skin: Use gentle, fragrance-free moisturisers and wear sunscreen when outdoors, as your skin may become highly sensitive during treatment.

verifiedApollotooltip

  • Nonsteroidal anti-inflammatory drugs (NSAIDs): Medicines like ibuprofen or naproxen can slow down the removal of Vrtu 100 mg Injection 10 ml from your body, increasing the risk of severe side effects.
  • Kidney-damaging medicines: Other medications that can strain the kidneys may increase the toxicity of Vrtu 100 mg Injection 10 ml if used at the same time.

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verifiedApollotooltip

No clinically significant food interactions are known with Vrtu 100 mg Injection 10 ml when used as directed.

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[CHEMOTHERAPY]

FAQs

Your doctor may prescribe folic acid and vitamin B12 before and during treatment with Vrtu 100 mg Injection 10 ml to help protect healthy cells and reduce the risk and severity of certain side effects, particularly blood-related and gastrointestinal side effects. Take these supplements exactly as directed by your doctor.
Hair thinning or mild hair loss can occur during treatment with Vrtu 100 mg Injection 10 ml, although complete hair loss is less common than with many other chemotherapy medicines. Speak with your doctor if you are concerned or if hair loss becomes troublesome.
This medicine can cause severe fatigue, dizziness, or weakness. Avoid driving or operating machinery until you know how the treatment affects you. Talk to your doctor.
No, this medicine can cause severe harm to an unborn baby. Both men and women should use highly effective birth control during treatment and for several months afterwards. Talk to your doctor.
The medicine is typically given once every three weeks, but your oncologist will determine the exact schedule based on your response to the therapy. Talk to your doctor.
It is best to avoid alcohol, as it can worsen liver strain, dehydration, and fatigue associated with your treatment. Talk to your doctor.
You should avoid live vaccines because your immune system may be weakened by the treatment, which could make the vaccine unsafe. Talk to your doctor.
Skin rashes are a known side effect. Your doctor may prescribe steroid tablets to take before your injection to prevent this, but you should report any new skin changes immediately. Talk to your doctor.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

Plot No. 45-A, Office No. 301-B, Amar Plaza, Hasanpur Flyover, East, New Delhi-110092, Delhi, India
Other Info - VRT0002
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