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Vozole Eye Drops is an anti-fungal medication used to treat fungal eye infections. Vozole Eye Drops works by inhibiting ergosterol production, a key component of fungal cell membranes, leading to fungal cell death. It effectively treats fungal eye infections like keratitis and endophthalmitis by disrupting fungal cell integrity. In some cases, this medicine may cause side effects such as a slight burning or stinging sensation and minor visual disturbances. Avoid touching the tip of the container to the eye, eyelids, or surrounding areas, as it may contaminate the product.

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Written By ,
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

VORICONAZOLE-30MG

Manufacturer/Marketer :

Aurolab

Consume Type :

Ophthalmic

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Vozole Eye Drops

The medicine Vozole Eye Drops is a specialised eye drop used to treat serious fungal infections of the eye, such as fungal keratitis. Its main medical purpose is to target and eliminate harmful fungal organisms that have invaded the cornea or other parts of the eye. By stopping these pathogens from multiplying, it helps clear the infection and prevents further damage to your vision.

To achieve the best results, you must apply Vozole Eye Drops exactly as prescribed, maintaining a highly consistent schedule throughout the day. Skipping applications or stopping too early can allow the fungal infection to return stronger and become harder to treat. You should apply these drops directly into the affected eye as directed by your doctor. During treatment, it is important to stop wearing contact lenses and protect your eyes from wind and dust to support proper healing.

In many countries, Vozole Eye Drops eye drops are specially prepared (compounded) by a hospital or speciality pharmacy rather than being a commercially available eye drop. Your doctor or pharmacist will advise you on where to obtain your prescribed preparation.

While using Vozole Eye Drops, you may experience some mild, temporary side effects like a slight burning sensation, watery eyes, or temporary blurry vision. However, if you develop severe eye pain, sudden changes in your vision, or signs of an allergic reaction like swelling, you must contact your doctor immediately. Seeking prompt medical advice ensures that any serious complications are managed quickly and safely.

Before starting treatment, talk to your doctor if you have any other pre-existing eye conditions, severe dry eyes, or a history of eye surgeries. Do not use this medicine if you have a known severe allergy to any of the ingredients in the eye drops. Your doctor will evaluate your eye health to determine if this is the safest treatment option for you.

It is also vital to inform your healthcare provider about all other eye drops or oral medications you are using, as some treatments may interfere with how well Vozole Eye Drops works. If you are pregnant, planning to become pregnant, breastfeeding, or are caring for an elderly patient, consult your doctor before using this medication to ensure its safe application.

Uses of Vozole Eye Drops

Your doctor may prescribe Vozole Eye Drops to help manage the following conditions:

  • Fungal keratitis: Vozole Eye Drops helps by directly treating fungal infections of the cornea (the clear front surface of the eye), stopping the growth of the fungi causing the painful ulcer or inflammation.
  • Fungal endophthalmitis: Vozole Eye Drops eye drops may be used as part of the treatment plan for certain fungal infections inside the eye. However, because these infections are serious, your eye specialist may also prescribe eye injections, oral medications, or other treatments, depending on the severity of the infection. 

Key Benefits

Using Vozole Eye Drops provides critical, targeted benefits to help your eye heal safely and comfortably:

  • Targeted infection control: Because this medicine is applied directly to the eye as a drop, it delivers a high concentration of the active ingredient straight to the site of infection, ensuring rapid action where it is needed most.
  • Protection of your vision: By aggressively stopping fungal growth, Vozole Eye Drops helps prevent permanent scarring of the cornea, which is essential for preserving your long-term eyesight.
  • Relief from painful symptoms: As the underlying fungal infection clears, you will experience a reduction in distressing symptoms such as severe eye pain, redness, sensitivity to bright light, and constant watering.
Side effects of Vozole Eye Drops
  • Cool the burn by using cool (not cold) running water to reduce tissue damage and pain.
  • Slowly remove any tight clothing or jewellery from the burned area.
  • After cooling, apply a topical ointment like aloevera gel or a mild antibiotic cream to help with healing.
  • Use a clean bandage to protect the burn area from further irritation.
  • Take over-the-counter pain medication if needed.
  • Do not apply butter or other greasy substances, as they can trap bacteria and hinder healing.
  • If the burn covers a large area of skin or if the burn appears to be deeper than the top layer of skin, with blisters or significant redness, consult the doctor and get treated.

Directions for Use

  • Follow the labelled instructions or use Vozole Eye Drops as prescribed by the doctor.
  • Lie down and tilt your head backwards. Pull your lower eyelid gently with your index finger to form a pocket. Instill the number of drops advised by the doctor into the pocket of the lower eyelid. Close your eyes for 1-2 minutes.
  • Avoid touching the container tip to your eye or lids to prevent contamination.

How Vozole Eye Drops Works

The medicine Vozole Eye Drops belongs to a group of antifungal medicines called triazoles. It works by blocking an enzyme called lanosterol 14-alpha-demethylase (CYP51), which fungi need to produce ergosterol—a key component that keeps their cell membranes intact. Without enough ergosterol, the fungal cell membrane becomes weak and leaky, causing the fungal cells to die. This stops the fungi from growing and multiplying, allowing your body's natural defences to help clear the remaining infection. Without this key component, the fungal cell membranes become weak and leaky, causing the fungal cells to break open and die. By stopping the fungi from growing and multiplying, Vozole Eye Drops allows your body's natural defence systems to step in and completely clear the remaining infection from your eye.
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Alcohol

Consult your doctor

No data is available on the interaction of alcohol and Vozole Eye Drops. Please consult your doctor if you have concerns.

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Pregnancy

Consult your doctor

Limited data is available on the use of Vozole Eye Drops in pregnancy. Please consult your doctor if you are pregnant or planning to become pregnant before using this medication.

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Breast Feeding

Consult your doctor

It is unknown whether Vozole Eye Drops passes into breast milk or affects a nursing baby. Please consult your doctor if you are breastfeeding.

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Driving

Caution

Vozole Eye Drops is known to cause blurry vision. Therefore, do not drive or operate any machinery that requires concentration.

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Liver

Consult your doctor

It is not known whether Vozole Eye Drops can be used in liver-impaired patients. If you have liver disease, please inform your doctor before using this medicine.

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Kidney

Consult your doctor

It is not known whether Vozole Eye Drops can be used in kidney-impaired patients. If you have kidney problems, please inform your doctor before using this medicine.

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Children

Unsafe

The safety and efficacy of Vozole Eye Drops have not been established in children below 12 years of age. Therefore, it is advised to consult a doctor before administering Vozole Eye Drops to your children to ensure safety.

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Heart

Caution

Vozole Eye Drops should be used with caution in patients with heart problems. Therefore, please consult your doctor before using Vozole Eye Drops.

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Geriatrics

Consult your doctor

Vozole Eye Drops should be used under medical supervision in geriatric patients due to increased risk of side effects. Therefore, please consult your doctor before using Vozole Eye Drops.

What if I have taken an overdose of Vozole Eye Drops

An accidental overdose of eye drops in the eye is unlikely to cause serious harm. If you accidentally put too many drops in your eye, rinse it thoroughly with clean, warm water. If anyone accidentally swallows the eye drop solution, contact a doctor or seek emergency medical attention right away.

Diet & Lifestyle Advise

  • Avoid contact lenses: Do not wear contact lenses of any kind until your doctor explicitly tells you your infection has completely cleared and it is safe to use them again.
  • Wear protective sunglasses: Use sunglasses when outdoors to shield your healing eyes from bright sunlight, wind, dust, and pollen, which can cause extra irritation.
  • Practice strict hand hygiene: Wash your hands with soap and water before and after touching your face or applying your eye drops to prevent introducing new bacteria or spreading the infection.
  • Discard contaminated eye makeup: Throw away any eye makeup, brushes, or facial applicators you used around the time your eye infection started to prevent reinfection later.
  • Avoid swimming: Stay out of swimming pools, hot tubs, and natural bodies of water during treatment to protect your vulnerable eyes from irritating chemicals and environmental germs.
health query

Have a query?

How Soon It Starts Working

  • The time required for Vozole Eye Drops to start to work: Vozole Eye Drops starts to show its action within 30-60 minutes of instillation.
  • The time for which the effects of Vozole Eye Drops last: The effect of Vozole Eye Drops usually lasts for 6-8 hours.

What if you forget to take Vozole Eye Drops

If you miss a dose, apply the missed drop as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and resume your regular routine. Do not apply a double dose to make up for a missed one.

Storage

• Store the medicine according to the storage instructions on the product label, kept refrigerated at 2°C to 8°C.

Drug Warnings

  • Check the liquid first: Always inspect the eye drop solution before each use. Do not use the medicine if the liquid has changed colour, looks cloudy, or contains visible floating particles.
  • Maintain dropper sterility: Never touch the dropper tip with your fingers, your eye, or any other surface, as this can easily contaminate the medicine and lead to worse eye infections.
  • Space out other eye drops: If you use other eye drops or eye ointments, wait at least 10 to 15 minutes after applying Vozole Eye Drops before using any other product so the drops are not washed out.
  • Do not drive immediately: Your vision may become temporarily blurry right after using these eye drops. Wait until your vision is completely clear before driving, operating machinery, or doing anything that requires sharp eyesight.
  • Finish the entire course: Do not stop using the drops early, even if your symptoms disappear. Fungal infections can live deep in the eye tissue and may return if treatment is stopped prematurely.

Drug-Drug Interactions

verifiedApollotooltip
  • Other eye medications: Applying other eye drops or eye ointments immediately before or after Vozole Eye Drops may reduce how much medicine is absorbed by your eye. Always space your eye medications by at least 10 to 15 minutes. Although only a very small amount of the medicine is usually absorbed into the bloodstream from eye drops, tell your doctor about all the medicines you take, including prescription medicines, over-the-counter products, and herbal supplements. This is especially important if you take medicines that require careful dose monitoring, so your doctor can decide if any extra precautions are needed. 

Drug-Drug Interactions

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How does the drug interact with Vozole Eye Drops:
Using Sparfloxacin together with Vozole Eye Drops can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Vozole Eye Drops with Sparfloxacin is not recommended, please consult a doctor before taking it. You should seek immediate medical attention if you develop dizziness, shortness of breath, or heart palpitations. Do not stop using any medications without talking to a doctor.
How does the drug interact with Vozole Eye Drops:
Co-administration of Vozole Eye Drops with Ziprasidone can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Ziprasidone with Vozole Eye Drops together can result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience dizziness, shortness of breath, or heart palpitations. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Vozole Eye Drops:
Coadministration of Vozole Eye Drops with Efavirenz can alter the blood levels and effects of both medications.

How to manage the interaction:
Taking Vozole Eye Drops with Efavirenz can be taken if a doctor has advised it. Contact a doctor if you experience vomiting, dizziness, difficulty concentrating. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Vozole Eye Drops:
Coadministration of Sirolimus and Vozole Eye Drops can increase blood levels and side effects of Vozole Eye Drops.

How to manage the interaction:
Taking Vozole Eye Drops with Sirolimus is generally avoided as it can result in an interaction, please consult a doctor before taking it. Contact a doctor if you experience nausea, fever, abdominal pain, or yellowing of the skin or eyes. Do not stop using any medication without consulting a doctor.
VoriconazoleVoclosporin
Critical
How does the drug interact with Vozole Eye Drops:
Using Voclosporin together with Vozole Eye Drops may significantly increase the blood levels of Voclosporin.

How to manage the interaction:
Taking Vozole Eye Drops with Voclosporin is not recommended, please consult a doctor before taking it. Do not stop using any medications without talking to a doctor.
How does the drug interact with Vozole Eye Drops:
Using alfuzosin together with Vozole Eye Drops may significantly increase the blood levels and effects of alfuzosin.

How to manage the interaction:
Taking Vozole Eye Drops with Alfuzosin is not recommended, please consult a doctor before taking it. Call a doctor if you experience dizziness, headache, nasal congestion, or heart palpitation. Do not stop using any medications without talking to a doctor.
How does the drug interact with Vozole Eye Drops:
Using Lovastatin together with Vozole Eye Drops may significantly increase the blood levels of Lovastatin.

How to manage the interaction:
Taking Vozole Eye Drops with Lovastatin is not recommended, please consult a doctor before taking it. You should also seek immediate medical attention if you experience fever, joint pain or swelling, vomiting, dark-colored urine, and/or yellowing of the skin or eyes. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Vozole Eye Drops:
Co-administration of Ranolazine together with Vozole Eye Drops may significantly increase the blood levels and effects of Ranolazine.

How to manage the interaction:
Taking Ranolazine with Vozole Eye Drops together can result in an interaction, but it can be taken if a doctor has advised it. Consult a doctor if you experience dizziness, or fast or pounding heartbeats. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Vozole Eye Drops:
Using ivabradine together with Vozole Eye Drops may significantly increase the blood levels and effects of ivabradine.

How to manage the interaction:
Taking Ivabradine with Vozole Eye Drops together is generally avoided as it can result in an interaction, it can be taken if a doctor has advised it. However, contact a doctor immediately if you experience dizziness, shortness of breath, rapid heartbeat. Do not discontinue any medications without consulting a doctor.
VoriconazoleConivaptan
Critical
How does the drug interact with Vozole Eye Drops:
Using Conivaptan together with Vozole Eye Drops may significantly increase the blood levels and effects of conivaptan.

How to manage the interaction:
Taking Vozole Eye Drops with Conivaptan is not recommended, please consult your doctor before taking it. Call a doctor if you experience difficulty swallowing, trouble speaking, trouble controlling body movements. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

verifiedApollotooltip
  • No clinically significant food interactions are known with Vozole Eye Drops when used as directed.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTIFUNGALS]

FAQs

Vozole Eye Drops is an anti-fungal medication used for the treatment of fungal infections of the eye.
Vozole Eye Drops contains voriconazole. It works by inhibiting the production of ergosterol, a key component of fungal cell membranes that maintains their structural integrity and function. By blocking ergosterol production, it creates holes in the fungal cell membranes, ultimately leading to fungal cell death which effectively treats fungal eye infections, including keratitis and endophthalmitis, by disrupting fungal cell integrity and preventing further growth and replication.
Yes, the use of Vozole Eye Drops can cause blurry vision for the short term. Therefore, please do not drive or operate heavy machinery which requires concentration to avoid any mishappening.
No, you should not use Vozole Eye Drops if you are wearing contact lenses. If you wear contact lenses or are wearing them, remove them before using Vozole Eye Drops, and you can put them back 10 minutes after using Vozole Eye Drops.
No, Vozole Eye Drops should not be used simultaneously with other eye medications. At least, a gap of 5 minutes should be maintained between using two eye medications.
The side effects of Vozole Eye Drops include slight burning or stinging sensation and minor visual disturbances. most of these side effects do not require medical attention and gradually resolve over time. However, please consult the doctor if any of these symptoms persist or worsen.
No, you must not wear contact lenses while you have an active fungal eye infection or during your treatment. Contact lenses can trap the fungus against your cornea and interfere with the action of the medicine, making the infection worse. Talk to your doctor to find out when it is safe to wear your lenses again.
Fungal eye infections are serious and heal very slowly, often requiring several weeks of continuous treatment. While you may notice an improvement in your symptoms within the first week, you must complete the entire treatment course to ensure the infection is completely gone. Talk to your doctor if your symptoms do not improve.
It is very common to feel a mild, temporary stinging or burning sensation in your eye right after applying the drops. This feeling usually goes away within a few minutes. However, if the burning is severe, worsens with each application, or is accompanied by swelling, stop using the drops and talk to your doctor immediately.
You should exercise caution when using any medication during pregnancy or while breastfeeding. Although Vozole Eye Drops is applied directly to the eye, a small amount can still enter your bloodstream. Talk to your doctor to discuss the benefits and risks of using these eye drops during these times.
Keeping Vozole Eye Drops in the refrigerator at 2°C to 8°C is necessary to maintain its chemical stability and prevent the growth of harmful bacteria or fungi in the bottle. Do not freeze the drops, and always keep the cap tightly shut. Talk to your pharmacist if you have questions about proper storage.
Pressing the inner corner of your eye close to your nose for 1 to 2 minutes blocks the tear duct. This simple action prevents the eye drops from draining away too quickly, ensuring the medicine stays on your eye where it is needed and reducing the amount of medicine absorbed into the rest of your body. Talk to your doctor or pharmacist to learn more.
Yes, you can use other eye drops if they are prescribed by your doctor, but you must space them out. Wait at least 10 to 15 minutes after using Vozole Eye Drops before applying any other eye drops or ointments to ensure both medications work properly. Talk to your doctor or pharmacist about your complete eye care schedule.
Once opened, eye drops are susceptible to contamination and lose their sterile quality over time. Most prepared antifungal eye drops are only safe to use for up to 14 days after opening or reconstitution. Talk to your pharmacist to find out the exact discard date for your specific prescription.

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Country of origin

INDIA

Manufacturer/Marketer address

No: 1 , Sivagangai Main Road, Veerapanjan, Madurai - 625 020, Tamil Nadu, India.
Other Info - VOZ0016
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