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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
Vorihope 200 mg Injection is used to treat a broad range of fungal infections. It contains 'Voriconazole' that kills or prevents fungus by inhibiting an enzyme in fungi responsible for its normal fat metabolism, thereby interfering with the fungal cell membrane formation. As a result, fungal cells get killed, or their growth is minimized. Common side effects of Vorihope 200 mg Injection are injection site reactions, peripheral oedema, headache, diarrhoea, vomiting, abdominal pain, chest pain, nausea, fever, anxiety, insomnia, confusion, weakness, tingling sensation, sleepiness, dizziness, irregular heartbeats, low blood pressure, stomach upset, constipation, rashes, itchiness, red skin, back pain and chills.
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Whats That

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Composition :

VORICONAZOLE-200MG

Manufacturer/Marketer :

Abbott India Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Vorihope 200 mg Injection

Vorihope 200 mg Injection belongs to the class of medicines known as 'antifungals' used to treat a broad range of fungal infections. A fungal infection is caused when a fungus invades and affects any body part, including the mouth, throat, oesophagus, lungs, bladder, genital area and blood.

Vorihope 200 mg Injection contains 'Voriconazole' that kills or prevents fungus by inhibiting an enzyme in fungi responsible for its normal fat metabolism, thereby interfering with the fungal cell membrane formation. As a result, fungal cells get killed, or their growth is minimized.

Vorihope 200 mg Injection will be administered by a qualified healthcare professional. In some cases, you may experience certain common side effects, such as injection site reactions, peripheral oedema, headache, diarrhoea, vomiting, abdominal pain, chest pain, nausea, fever, anxiety, insomnia, confusion, weakness, tingling sensation, sleepiness, dizziness, irregular heartbeats, low blood pressure, stomach upset, constipation, rashes, itchiness, red skin, back pain and chills. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Before taking Vorihope 200 mg Injection, let your doctor know about your medical condition, sensitivities, and medications. Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Vorihope 200 mg Injection may affect your ability to drive or operate machinery; thus, avoid driving or using machinery.

Uses of Vorihope 200 mg Injection

Treatment of Fungal infections

Directions for Use

• Your doctor will determine the dosage and frequency depending on your condition.• Vorihope 200 mg Injection will be administered by a healthcare professional.• Do not self-administer.

Medicinal Benefits

Vorihope 200 mg Injection belongs to the class of medicines known as 'antifungal agents', used to treat a broad range of fungal infections, including aspergillosis (a disease caused by Aspergillus), candidiasis (fungal infection caused by yeast), coccidioidomycosis (an infection caused by the fungus Coccidioides), histoplasmosis (an infection caused by a fungus called Histoplasma), and penicilliosis (a disease caused by the fungus Talaromyces marneffei). It also effectively treats CNS fungal infections transmitted by epidural injection of contaminated steroids. On the other hand, it can prevent fungal infections in people undergoing bone marrow transplants. Vorihope 200 mg Injection works by killing or preventing fungi or yeast by inhibiting an enzyme in fungi responsible for its normal fat metabolism, thereby interfering with the fungal cell membrane formation. As a result, fungal cells get killed, or their growth is minimized.

How Vorihope 200 mg Injection Works

Vorihope 200 mg Injection contains 'Voriconazole' that kills or prevents fungus by inhibiting an enzyme in fungi responsible for its normal fat metabolism, thereby interfering with the fungal cell membrane formation. As a result, fungal cells get killed, or their growth is minimized.

Storage

• Store in a cool and dry place away from sunlight.
• Keep Vorihope 200 mg Injection out of the sight and reach of children.
• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Vorihope 200 mg Injection
  • Your doctor may recommend regular liver function tests (LFT) to monitor liver enzyme levels.
  • To support your liver, eat a healthy diet with lots of fruits, vegetables, lean proteins, and healthy fats.
  • Avoid eating processed meats, sugary foods, and unhealthy fats.
  • Limit your alcohol consumption, since too much can worsen liver function and contribute to high levels of Alkaline Phosphatase (ALP).
  • Stay active with regular exercise, drink plenty of water, and try to avoid harmful chemicals that can damage your liver.
  • Quit smoking to lower the risk of elevated ALP levels.
  • Increased creatinine levels must be corrected immediately with the help of a doctor.
  • Reduce strenuous activities that can lead to muscle breakdown and production of creatinine.
  • Sleep for 7-8 hours per night to assist your body in repairing and rebuilding tissue.
  • Manage your blood pressure by implementing changes in lifestyle like losing weight, reducing stress and exercising regularly.
  • Avoid smoking and drinking alcohol.
  • Skin rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Eat more potassium-rich foods, like bananas, leafy greens, sweet potatoes, avocados, and nuts/seeds.
  • Choose potassium-fortified foods such as orange juice and sports beverages.
  • Limit potassium-depleting foods like caffeine, processed foods, and sugary drinks.
  • Exercise regularly, like walking or yoga, to help maintain potassium balance.
  • Inform your doctor if hypokalemia doesn't improve or worsen despite treatment.

What if I have taken an overdose of Vorihope 200 mg Injection

As Vorihope 200 mg Injection is a parenteral formulation administered by experienced medical staff, the chance of overdose may be less. However, if you think there has been an overdose or experiencing any adverse events, get medical care right away.

Drug Warnings

Inform your doctor about your medical conditions, sensitivities, and medications you are using. And also, let your doctor know if you are pregnant, planning to become pregnant, or breastfeeding. Women of childbearing potential should always use effective contraception during treatment. Please inform your doctor if you are suffering from a heart problem like an irregular heartbeat, slow heart rate or abnormality in ECG (electrocardiogram), QT prolongation, or if you have hereditary intolerance for galactose, Lapp lactase deficiency, or glucose-galactose malabsorption. Vorihope 200 mg Injection may affect your ability to drive or operate machinery; thus, avoid driving or using machinery.

Drug-Drug Interactions

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VoriconazoleErgotamine
Critical

Drug-Drug Interactions

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VoriconazoleErgotamine
Critical
How does the drug interact with Vorihope 200 mg Injection:
The serum concentration of Ergometrine can be increased when it is combined with Vorihope 200 mg Injection.

How to manage the interaction:
Taking Ergotamine with Vorihope 200 mg Injection is not recommended, please consult your doctor before taking it.
How does the drug interact with Vorihope 200 mg Injection:
When Vorihope 200 mg Injection is taken with Rifabutin, the amount of Vorihope 200 mg Injection in the blood may decrease.

How to manage the interaction:
Taking Rifabutin with Vorihope 200 mg Injection is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, consult a doctor immediately If you experience any unusual symptoms. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Vorihope 200 mg Injection:
Using Sparfloxacin together with Vorihope 200 mg Injection can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Vorihope 200 mg Injection with Sparfloxacin is not recommended, please consult a doctor before taking it. You should seek immediate medical attention if you develop dizziness, shortness of breath, or heart palpitations. Do not stop using any medications without talking to a doctor.
VoriconazoleQuinidine
Critical
How does the drug interact with Vorihope 200 mg Injection:
Using Quinidine together with Vorihope 200 mg Injection can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Vorihope 200 mg Injection with Quinidine is not recommended, please consult a doctor before taking it. You should seek immediate medical attention if you develop dizziness, shortness of breath, or heart palpitations. Do not stop using any medications without talking to a doctor.
How does the drug interact with Vorihope 200 mg Injection:
Coadministration of Sirolimus and Vorihope 200 mg Injection can increase blood levels and side effects of Vorihope 200 mg Injection.

How to manage the interaction:
Taking Vorihope 200 mg Injection with Sirolimus is generally avoided as it can result in an interaction, please consult a doctor before taking it. Contact a doctor if you experience nausea, fever, abdominal pain, or yellowing of the skin or eyes. Do not stop using any medication without consulting a doctor.
VoriconazoleSaquinavir
Critical
How does the drug interact with Vorihope 200 mg Injection:
Using Saquinavir together with Vorihope 200 mg Injection can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Vorihope 200 mg Injection with Saquinavir is not recommended, please consult a doctor before taking it. You should seek immediate medical attention if you develop dizziness, shortness of breath, or heart palpitations (irregular heartbeat). Do not stop using any medications without talking to a doctor.
How does the drug interact with Vorihope 200 mg Injection:
Using Nimodipine together with Vorihope 200 mg Injection may significantly increase the risk of serous side effects.

How to manage the interaction:
Taking Nimodipine with Vorihope 200 mg Injection is not recommended, as it may lead to an interaction, but it can be taken if prescribed by the doctor. However, if you experience symptoms such as irregular heart rhythm, swelling, and low blood pressure, consult the doctor. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Vorihope 200 mg Injection:
Taking Vorihope 200 mg Injection together with primidone may reduce the blood levels of Vorihope 200 mg Injection, which may make the medication less effective.

How to manage the interaction:
Although there is an interaction between Vorihope 200 mg Injection and Primidone, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms contact a doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Vorihope 200 mg Injection:
Using Lurasidone together with Vorihope 200 mg Injection may result in significantly higher Lurasidone blood levels.

How to manage the interaction:
While Lurasidone and Vorihope 200 mg Injection may interact, it is not recommended that they be used unless prescribed by a doctor. Consult a doctor if you have any abnormal muscle activity, dizziness, headache, or heart palpitations. Do not discontinue any medications without consulting a doctor.
VoriconazoleVoclosporin
Critical
How does the drug interact with Vorihope 200 mg Injection:
Using Voclosporin together with Vorihope 200 mg Injection may significantly increase the blood levels of Voclosporin.

How to manage the interaction:
Taking Vorihope 200 mg Injection with Voclosporin is not recommended, please consult a doctor before taking it. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • In wet places such as changing rooms and gym showers, don’t walk barefoot to prevent fungal infections.
  • Do not scratch the affected skin, as it can spread the infection to other body parts.
  • Avoid sharing towels, combs, bedsheets, shoes or socks with others.
  • Wash your bedsheets and towels regularly.
  • It is advisable to follow a candida diet during fungal infections. This diet excludes sugar, gluten, certain dairy products, and alcohol. Switch to low-sugar fruits, non-starchy vegetables and gluten-free foods. A very-high sugar or high-carbohydrate diet may increase the count of Candida in some people.

Habit Forming

No

Therapeutic Class

ANTIFUNGALS
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Alcohol

Consult your doctor

It is not known if alcohol affects Vorihope 200 mg Injection. Please consult your doctor.

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Pregnancy

Caution

Vorihope 200 mg Injection is generally not recommended in pregnancy. Your doctor may prescribe this medicine if the benefit to the mother outweighs the potential risk to the fetus.

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Breast Feeding

Caution

If you are breastfeeding, please inform your doctor. It is not known if Vorihope 200 mg Injection passes into breastmilk. Your doctor may advise you to stop breastfeeding before starting the treatment with Vorihope 200 mg Injection.

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Driving

Unsafe

Vorihope 200 mg Injection may affect your ability to drive or operate machinery; thus, avoid driving or using machinery.

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Liver

Caution

Inform your doctor if you have liver problems before receiving Vorihope 200 mg Injection.

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Kidney

Caution

Inform your doctor if you have kidney problems before receiving Vorihope 200 mg Injection.

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Children

Caution

Your doctor may prescribe this medicine if the benefits outweigh the risks.

Have a query?

FAQs

Vorihope 200 mg Injection is used to treat Fungal infections.

Vorihope 200 mg Injection contains Voriconazole that kills or prevents fungus by inhibiting an enzyme in fungi responsible for its normal fat metabolism, thereby interfering with the fungal cell membrane formation. As a result, fungal cells get killed, or their growth is minimized.

Vorihope 200 mg Injection can also prevent fungal infections in people undergoing bone marrow transplants.

Vorihope 200 mg Injection may not be suitable in patients with known hypersensitivity to any of the components present in Vorihope 200 mg Injection; or with a hereditary intolerance for galactose, Lapp lactase deficiency, or glucose-galactose malabsorption.

You can take Vorihope 200 mg Injection with contraceptive pills. However, some studies show a chance of an increase in the body's hormonal levels when you take Vorihope 200 mg Injection with a combined pill. Seek your doctor's advice if any side effects occur.

Yes, fungal infection is a contagious skin condition that spreads from one person to another through direct skin-to-skin contact or by contact with contaminated soil or surfaces and infected animals. Therefore, it is recommended to avoid close direct contact until the infection is clear and avoid sharing things with the infected person, as it can also spread the infection.

Vorihope 200 mg Injection can use women of childbearing potential; however, they must always use effective contraception during treatment.

Country of origin

India

Manufacturer/Marketer address

401, Lsc, C-Block, Mohan Place Saraswati Vihar Delhi Dl 110034 In.
Other Info - VOR0107

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