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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Volrin TH 2mg/37.5mg Injection is used to treat acute musculoskeletal pain and muscle spasms. It contains Diclofenac and Thiocolchicoside. Diclofenac is a non-steroidal anti-inflammatory drug (pain killer/NSAID) with analgesic properties. It inhibits cyclo-oxygenase (COX) enzymes and further prevents the formation of chemical messengers, 'prostaglandins' (PGs), that cause pain and swelling at the injured or damaged site. Thiocolchicoside is a muscle relaxant that works on the spinal cord and brain centres. This process helps reduce muscle stiffness and improves muscle movements, thus relieving pain due to muscle spasms.
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Manufacturer/Marketer :

Werke Healthcare

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

About Volrin TH 2mg/37.5mg Injection

Volrin TH 2mg/37.5mg Injection is a combination medication primarily used to treat acute musculoskeletal pain and muscle spasms. Pain is a symptom triggered by the nervous system, causing uncomfortable sensations in the body.

Volrin TH 2mg/37.5mg Injection is a combination of Diclofenac and Thiocolchicoside. Diclofenac is a non-steroidal anti-inflammatory drug (pain killer/NSAID) with analgesic properties. It inhibits cyclo-oxygenase (COX) enzymes and further prevents the formation of chemical messengers, 'prostaglandins' (PGs), that cause pain and swelling at the injured or damaged site. Thiocolchicoside is a muscle relaxant that works on the centres of the spinal cord and brain. This process helps reduce muscle stiffness and improves muscle movements, thus relieving pain due to muscle spasms.

A healthcare professional will administer this medicine. Common side effects of Volrin TH 2mg/37.5mg Injection include headache, stomach upset, constipation, dizziness, drowsiness, diarrhoea, pain, swelling, and redness at the injection site. These side effects are not familiar to everyone and vary individually. However, if the side effects are persistent, please consult your doctor.

Before starting Volrin TH 2mg/37.5mg Injection, inform your doctor if you have any liver, heart or kidney diseases, high blood pressure, diabetes, stomach ulcers, asthma, and auto-immune conditions like systemic lupus erythematosus. Pregnant and breastfeeding women should consult their doctor before using Volrin TH 2mg/37.5mg Injection. Avoid consuming alcohol while undergoing treatment with Volrin TH 2mg/37.5mg Injection. This medicine is not recommended for children and adolescents below 18 years of age as safety has not been established. However, please seek medical advice.

Uses of Volrin TH 2mg/37.5mg Injection

Treatment of Acute musculoskeletal pain and muscle spasms

Directions for Use

• Your doctor will determine the dosage and frequency depending on your condition.• Volrin TH 2mg/37.5mg Injection will be administered by a healthcare professional.• Do not self-administer.

Medicinal Benefits

Volrin TH 2mg/37.5mg Injection treats acute musculoskeletal pain and muscle spasms. It contains Diclofenac and Thiocolchicoside. Diclofenac is a non-steroidal anti-inflammatory drug (NSAID) and relieves pain. It inhibits cyclo-oxygenase (COX) enzymes that further prevent the formation of chemical messengers called 'prostaglandins' (PGs). These prostaglandins are produced at injury sites and cause pain and swelling. By blocking the COX enzymes' effect, lesser PGs are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site. Thiocolchicoside is a muscle relaxant that works on the centres of the spinal cord and brain. This process helps reduce muscle stiffness and improves muscle movements, thus relieving pain due to muscle spasms.

How Volrin TH 2mg/37.5mg Injection Works

Volrin TH 2mg/37.5mg Injection is a combination of Diclofenac and Thiocolchicoside. Diclofenac is a non-steroidal anti-inflammatory drug (pain killer/NSAID) with analgesic properties. It inhibits cyclo-oxygenase (COX) enzymes and further prevents the formation of chemical messengers, 'prostaglandins' (PGs), that cause pain and swelling at the injured or damaged site. Thiocolchicoside is a muscle relaxant that works on the centres of the spinal cord and brain. This process helps reduce muscle stiffness and improves muscle movements, thus relieving pain due to muscle spasms.

Storage

• Store in a cool and dry place away from sunlight.
• Keep out of the sight and reach of children.
• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of Volrin TH 2mg/37.5mg Injection

As Volrin TH 2mg/37.5mg Injection is a parenteral formulation administered by experienced medical staff, the chance of overdose may be less. However, if you think there has been an overdose or experiencing any adverse events, get medical care right away.

Drug Warnings

Inform your doctor if you have any liver, heart or kidney diseases, high blood pressure, diabetes, stomach ulcers, gastrointestinal diseases, asthma, and autoimmune diseases (systemic lupus erythematosus) before being treated with Volrin TH 2mg/37.5mg Injection. Please consult your doctor before starting Volrin TH 2mg/37.5mg Injection if you have high cholesterol, chickenpox, porphyria (rare inherited disorder), hereditary disorders like Lapp lactase deficiency (lactose intolerance), galactose intolerance, glucose-galactose malabsorption (small intestines not being able to absorb and use glucose and galactose), fits, and blood clotting disorders. Do not take any other NSAIDs for pain relief along with Volrin TH 2mg/37.5mg Injection unless prescribed. Stop using Volrin TH 2mg/37.5mg Injection and consult your doctor immediately if you have stomach pain or any signs of bleeding in the intestine or stomach, such as blood in stools. Volrin TH 2mg/37.5mg Injection is not recommended for pregnant and breastfeeding women; hence, please seek medical advice. This medicine may cause dizziness and drowsiness, so drive only if you are alert and focused. Volrin TH 2mg/37.5mg Injection is not recommended in children and adolescents below 18 years as safety and efficacy are not established.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Volrin TH 2mg/37.5mg Injection:
Co-administration of Volrin TH 2mg/37.5mg Injection with Meloxicam can increase the risk or severity of gastrointestinal side effects.

How to manage the interaction:
Taking Meloxicam with Volrin TH 2mg/37.5mg Injection is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, consult your doctor immediately if you experience symptoms such as dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not stop any medication without doctor's advise.
How does the drug interact with Volrin TH 2mg/37.5mg Injection:
Taking Volrin TH 2mg/37.5mg Injection with Enoxaparin can increase the risk of bleeding complications.

How to manage the interaction:
There may be a possible interaction between Volrin TH 2mg/37.5mg Injection and Enoxaparin, but they can be taken together if your doctor has prescribed them. However, consult your doctor immediately if you experience any unusual bleeding or bruising, swelling, vomiting, blood in your urine or stools, headache, dizziness, or weakness. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Volrin TH 2mg/37.5mg Injection:
Co-administration of Volrin TH 2mg/37.5mg Injection and Ramucirumab can cause bleeding and ulcers.

How to manage the interaction:
Co-administration of Volrin TH 2mg/37.5mg Injection and Ramucirumab can lead to an interaction; it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult your doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Volrin TH 2mg/37.5mg Injection:
Co-administration of Volrin TH 2mg/37.5mg Injection with Sirolimus may increase the risk or severity of kidney problems.

How to manage the interaction:
Co-administration of Volrin TH 2mg/37.5mg Injection and Sirolimus can lead to an interaction, but it can be taken if advised by a doctor. However, consult a doctor if you experience any symptoms like nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Volrin TH 2mg/37.5mg Injection:
Taking Volrin TH 2mg/37.5mg Injection and piroxicam can increase the risk of side effects such as ulcers, inflammation (redness, swelling), bleeding.

How to manage the interaction:
Co-administration of Volrin TH 2mg/37.5mg Injection and Piroxicam can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Volrin TH 2mg/37.5mg Injection:
Taking Volrin TH 2mg/37.5mg Injection with human immunoglobulin may increase the risk of kidney problems.

How to manage the interaction:
Although there is an interaction between Human immunoglobulin and Volrin TH 2mg/37.5mg Injection, you can take these medicines together if prescribed by a doctor. However, consult the doctor immediately if you experience symptoms such as nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not discontinue any medications without consulting a doctor.
DiclofenacSulindac
Severe
How does the drug interact with Volrin TH 2mg/37.5mg Injection:
Co-administration of Volrin TH 2mg/37.5mg Injection and sulindac can increase the risk of side effects.

How to manage the interaction:
Although there is a interaction between Volrin TH 2mg/37.5mg Injection and sulindac, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult your doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Volrin TH 2mg/37.5mg Injection:
Co-administration use of Volrin TH 2mg/37.5mg Injection with Dalteparin may increase the risk of bleeding complications.

How to manage the interaction:
Although taking Dalteparin with Volrin TH 2mg/37.5mg Injection may possibly lead to an interaction, they can be taken if a doctor prescribes it. Consult a doctor if you have any symptoms including dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that resembles coffee grounds, severe headache, and weakness. Without consulting a doctor, never stop taking any medication.
How does the drug interact with Volrin TH 2mg/37.5mg Injection:
Co-administration of Volrin TH 2mg/37.5mg Injection with tacrolimus may cause kidney problems.

How to manage the interaction:
Co-administration of Volrin TH 2mg/37.5mg Injection and Tacrolimus can lead to an interaction, it can be taken if advised by your doctor. However, consult your doctor if you experience nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not stop using any medications without a doctor's advice.
How does the drug interact with Volrin TH 2mg/37.5mg Injection:
Taking Volrin TH 2mg/37.5mg Injection with Ibrutinib can increase the risk of bleeding tendencies.

How to manage the interaction:
There may be a possible interaction between Volrin TH 2mg/37.5mg Injection and Ibrutinib, but they can be taken together if a doctor has prescribed them. However, consult a doctor immediately if you experience any unusual bleeding, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, or severe headaches. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Exercising regularly helps in muscle stretching, reducing spasm, tear and sprain incidence. Mild exercises, such as jogging and walking, are helpful for muscle stretching.
  • Massages can also be helpful to ease the pain.
  • Avoid wearing tight-fitting clothes; wear loose garments for proper blood circulation.
  • Rest well and get plenty of sleep.
  • Hot or cold therapy can help treat muscle spasms. Apply an ice or hot pack on the muscle for 15-20 minutes.
  • Stay hydrated; drink plenty of water.

Habit Forming

No

Therapeutic Class

MUSCLE RELAXANTS
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Alcohol

Caution

Please seek medical advice if you have a regular alcohol intake habit before taking Volrin TH 2mg/37.5mg Injection

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Pregnancy

Unsafe

Volrin TH 2mg/37.5mg Injection is not recommended during pregnancy as it may harm your developing baby. Please consult your doctor for more information.

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Breast Feeding

Unsafe

Volrin TH 2mg/37.5mg Injection is not recommended during breastfeeding as it may be excreted in breast milk. Please consult your doctor for more information.

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Driving

Caution

Volrin TH 2mg/37.5mg Injection may make you feel dizzy and sleepy. Do not drive or operate machinery if you experience dizziness or drowsiness after taking Volrin TH 2mg/37.5mg Injection.

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Liver

Caution

Volrin TH 2mg/37.5mg Injection should be used cautiously in patients with liver impairment/liver disease. If you have liver disease, please inform your doctor before receiving this medicine.

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Kidney

Caution

Volrin TH 2mg/37.5mg Injection should be used cautiously in patients with kidney impairment/liver disease. If you have kidney disease, please inform your doctor before receiving this medicine.

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Children

Unsafe

Volrin TH 2mg/37.5mg Injection is not recommended for use in children as the safety and efficacy data are not established. Please seek medical advice for more information.

Have a query?

FAQs

Volrin TH 2mg/37.5mg Injection is used to treat Acute musculoskeletal pain and muscle spasms.

Volrin TH 2mg/37.5mg Injection contains Diclofenac and Thiocolchicoside. Diclofenac works by blocking the action of certain chemical messengers that cause pain and inflammation at the injured or damaged site. Thiocolchicoside is a muscle relaxant which relieves muscle stiffness due to muscle spasms and improves muscle movements.

Diarrhoea can be a side-effect of Volrin TH 2mg/37.5mg Injection. Drink enough fluids and eat fibre-rich food if you experience diarrhoea. If you find blood in the stools (tarry stools) or experience excess diarrhoea, consult your doctor. Do not take anti-diarrhoeal medicine on your own.

Using other NSAIDs or painkillers is not advised while using Volrin TH 2mg/37.5mg Injection. Please seek medical advice for further information.

You are not recommended to take Volrin TH 2mg/37.5mg Injection with warfarin as simultaneous use of these two medicines may increase the effect of anti-coagulants/blood thinners and cause bleeding risk. Please seek medical advice for more information.

Country of origin

India
Other Info - VO50125

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