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compositionComposition:VERTEPORFIN-15MG
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Prescription Medicine
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Visudyne 15Mg Inj is a photosensitizing agent used in combination with photodynamic therapy (treatment with laser light) to treat the wet form of age-related macular degeneration, pathological myopia, or ocular histoplasmosis. It contains Verteporfin, which is distributed within the body through the blood vessels, including the blood vessels at the back of the eye. It is activated by light and closes up leaking blood vessels.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr. Lakshmithulasi Yarragunta , PharmD (PB)
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More about the Product

Composition :

VERTEPORFIN-15MG

Manufacturer/Marketer :

Novartis India Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Visudyne 15Mg Inj

Visudyne 15Mg Inj is a specialised medicine injected into the bloodstream to treat abnormal blood vessel growth in the back of the eye. It is primarily used to help prevent severe vision loss in people with specific eye conditions, such as the classic 'wet' form of age-related macular degeneration. By targeting and closing these leaking blood vessels, it helps protect your remaining eyesight.

This treatment is not a daily medication. It is given as a single intravenous infusion followed shortly after by a non-heat laser treatment, and your doctor may repeat the procedure every three months if necessary. To get the best results, you must strictly avoid exposing your skin and eyes to direct sunlight or bright indoor light for several days after each treatment.

While undergoing this treatment, you may experience temporary side effects like vision changes, dry eyes, or irritation where the medicine was injected. It is important to contact your eye doctor immediately if you notice a sudden, severe drop in your vision or severe skin reactions.

Do not take this if you have porphyria, a rare metabolic disorder that increases light sensitivity. Before starting treatment, tell your doctor if you have liver problems or any other medical conditions, as this may affect how your body processes the medicine.

Some medicines can make your skin even more sensitive to light, so tell your doctor about all drugs you are taking, especially other light-sensitizing medications. If you are pregnant, planning to become pregnant, breastfeeding, or are an elderly patient, discuss the benefits and risks with your healthcare provider first.

Uses of Visudyne 15Mg Inj

Your doctor may prescribe Visudyne 15Mg Inj to treat the following conditions to help seal abnormal blood vessels, reduce leakage, and preserve vision:

  • Classic wet age-related macular degeneration (AMD): Visudyne 15Mg Inj helps by closing abnormal, leaking blood vessels in the retina to slow down or prevent further loss of central vision.
  • Pathologic myopia: In cases of severe nearsightedness where abnormal blood vessels grow underneath the retina, this treatment helps seal these vessels to stabilize vision.
  • Presumed ocular histoplasmosis: For abnormal blood vessel growth caused by this fungal eye infection, Visudyne 15Mg Inj helps block the leaks and protect your sight.

Key Benefits

Using Visudyne 15Mg Inj as prescribed helps preserve vision, reduce retinal damage, and slow the progression of certain eye diseases. Here are the key benefits you can expect:

  • Helps preserve vision: Slows the progression of vision loss by sealing abnormal blood vessels and protecting the retina from further damage.
  • Reduces retinal swelling and scarring: Helps stop leakage from abnormal blood vessels, reducing swelling and lowering the risk of permanent retinal scarring.
  • Supports daily independence: By maintaining central vision, it helps many people continue everyday activities such as reading, recognising faces, and driving more safely, where appropriate.

Directions for Use

  • Visudyne 15Mg Inj will be administered by a healthcare professional.
  • Do not self-administer it.

How Visudyne 15Mg Inj Works

Visudyne 15Mg Inj contains verteporfin, a photosensitising medicine used in photodynamic therapy (PDT) to treat abnormal blood vessels in the eye. After it is injected into a vein, Visudyne 15Mg Inj travels through the bloodstream and selectively accumulates in the abnormal, leaking blood vessels beneath the retina. A few minutes later, your doctor shines a low-intensity, non-thermal laser light into the affected eye. The laser activates Visudyne 15Mg Inj, triggering a chemical reaction that damages and seals the abnormal blood vessels without directly harming the surrounding healthy retinal tissue. This helps reduce leakage, slow the progression of vision loss, and preserve central vision.
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Alcohol

Caution

Avoid or limit alcohol consumption as it may decrease the effects of Visudyne 15Mg Inj.

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Pregnancy

Caution

Verteporfin belongs to pregnancy category C. Visudyne 15Mg Inj should be used during pregnancy only if the benefits outweigh the risks.

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Breast Feeding

Unsafe

If you are a nursing mother, it is advised to stop breastfeeding for 48 hours after administration of Visudyne 15Mg Inj.

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Driving

Caution

Visudyne 15Mg Inj may cause vision problems. Avoid driving or operating heavy machinery until you know how this medicine affects you.

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Liver

Caution

If you have a history of liver problems, inform the doctor before receiving Visudyne 15Mg Inj. This medicine is not recommended if you have severe liver problems.

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Kidney

Consult your doctor

If you have a history of kidney problems, inform the doctor before receiving Visudyne 15Mg Inj.

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Children

Caution

The safety and effectiveness of Visudyne 15Mg Inj in children have not been established.

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Heart

Caution

Visudyne 15Mg Inj can affect blood pressure and heart rhythm, so if you have heart problems, your doctor may need to monitor you closely during treatment. It’s not strictly contraindicated, but full disclosure of your condition is essential before proceeding.

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Geriatrics

Caution

Geriatric patients can receive Visudyne 15Mg Inj, but doctors take extra care due to fragile veins and increased sensitivity to side effects. Using a large vein and close monitoring helps ensure safer administration.

What if I have taken an overdose of Visudyne 15Mg Inj

Because this medicine is carefully measured and injected by a healthcare provider, an overdose is highly unlikely. However, an overdose could make your skin and eyes extremely sensitive to light for a longer period. If you suspect an issue, contact your healthcare provider or seek immediate medical attention.

Diet & Lifestyle Advise

  • Avoid direct sunlight: Stay indoors and avoid direct sunlight for exactly 5 days after your treatment. Do not use tanning beds during this time.
  • Protect your skin: If you must go outside during the first 5 days, wear protective clothing, including long sleeves, pants, gloves, and a wide-brimmed hat. Normal sunscreens will not protect your skin from reactions caused by this medicine.
  • Protect your eyes: Wear dark, professional-grade sunglasses that block ultraviolet and visible light when outdoors or in bright indoor spaces for 5 days.
  • Manage indoor lighting: Avoid bright halogen lights or high-intensity examination lights. Use normal indoor lighting, as staying in complete darkness is not recommended; mild indoor light actually helps break down the medicine in your skin safely.
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How Soon It Starts Working

The time required for Visudyne 15Mg Inj to start to work: Visudyne 15Mg Inj ideally shows its action within 15 minutes after administration. The time for which the effects of Visudyne 15Mg Inj last: The effect of Visudyne 15Mg Inj lasts for 5 hours.

What if you forget to take Visudyne 15Mg Inj

This treatment is scheduled as an in-office procedure. If you miss your scheduled appointment, contact your eye clinic immediately to reschedule. Delaying your treatment can allow abnormal blood vessels to grow further, increasing the risk of permanent vision damage.

Storage

• Visudyne 15Mg Inj is usually stored and handled by healthcare professionals. Unopened vials should be stored below 25°C (77°F) in their original carton to protect them from light.

Drug Warnings

  • Check for leakage during infusion: Tell your doctor or nurse immediately if you feel any burning, stinging, or pain in your arm while the injection is being given. If the medicine leaks into the surrounding tissue, it can cause severe light-induced burns and tissue damage.
  • Wear your light-sensitivity wristband: You may be given a wristband or warning card to wear after treatment to remind healthcare workers of your temporary sensitivity to bright light in case of an emergency.
  • Delay dental or surgical procedures: Avoid any medical or dental procedures that require bright examination lights for 5 days after your treatment.
  • Do not rely on standard sunscreen: Keep in mind that topical sunscreens do not protect against the light-sensitivity reactions caused by this medicine. Only physical shade and protective clothing will work.

Drug-Drug Interactions

verifiedApollotooltip
  • Other photosensitizing medicines: Taking drugs like tetracyclines (antibiotics), sulfonamides, phenothiazines (mental health medications), or sulfonylureas (diabetes medications) can severely increase your risk of skin burns from light.
  • Vasodilators or vasoconstrictors: Medicines that change blood flow or affect blood vessels can alter how Visudyne 15Mg Inj reaches the blood vessels in your eye.
No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

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No clinically significant food interactions are known with Visudyne 15Mg Inj when used as directed. 

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[OPHTHALMOLOGIC AGENTS]

FAQs

Visudyne 15Mg Inj is used to treat Wet form of age-related macular degeneration, pathological myopia, or ocular histoplasmosis.
Visudyne 15Mg Inj is activated by light and closes up leaking blood vessels.
Visudyne 15Mg Inj may cause sensitivity to sunlight. Avoid direct sunlight and bright indoor lights for 5 days after treatment with Visudyne 15Mg Inj. If you must go outdoors during the first 5 days, wear protective clothing, a wide-brimmed hat, gloves, and dark sunglasses.
It is best to stay indoors as much as possible for the first 5 days. If you must go outside, you must wear protective clothing like long sleeves, a wide-brimmed hat, and dark sunglasses. Talk to your doctor for detailed instructions.
This medicine is designed to slow down or prevent further vision loss by sealing leaking blood vessels. It usually does not restore vision that has already been lost due to scarring. Talk to your doctor about what to expect.
Keeping your home in complete darkness actually delays the process of clearing the medicine from your body. Normal, low-intensity indoor light helps safely break down the drug in your skin. Talk to your doctor if you need advice on lighting.
Tell your healthcare provider immediately if you feel pain, burning, or swelling in your arm. This could mean the medicine is leaking out of the vein, which can cause severe skin burns. Talk to your doctor or nurse if you feel discomfort.
No, you should not drive yourself home. Your eyes will be dilated and highly sensitive to light, making it unsafe to drive. Please arrange for someone to take you home after your appointment. Talk to your doctor about safe travel plans.
Most patients are evaluated every 3 months. Your eye doctor will examine your retina and decide if you need another treatment based on whether the blood vessels are still leaking. Talk to your doctor to understand your specific treatment plan.
No, standard sunscreens do not protect against the specific light-sensitivity reactions caused by this medicine. You must rely on physical barriers like long clothing and staying indoors. Talk to your doctor for more safety tips.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

United States

Manufacturer/Marketer address

Sandoz House, Shiv Sagar Estate, Worli Mumbai -400 018, India
Other Info - VIS0006
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