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Vinbicel 50Mg/5Ml Injection is used to treat non-small cell lung cancer. It contains Vinorelbine, which works by stopping or slowing the growth of cancer cells in the body. This medication is recommended not to use if you are allergic to any of its components, if you are pregnant, think you might be pregnant or breastfeeding, if you have a low white blood cell count, have/had a severe infection within two weeks, have thrombocytopenia (low platelet count), or if you have taken or plan to receive yellow fever vaccination.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

VINORELBINE-50MG

Manufacturer/Marketer :

Celon Laboratories Pvt Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Vinbicel 50Mg/5Ml Injection

Vinbicel 50Mg/5Ml Injection is a prescription chemotherapy medication used to treat certain types of cancer, primarily non-small cell lung cancer. It works by targeting cancer cells to stop them from growing and spreading throughout the body. It is typically prescribed either on its own or in combination with other cancer medicines.

This treatment is given in scheduled cycles, meaning you will receive it at regular intervals (such as once a week) followed by a rest period. Keeping these appointments consistently is essential to ensure the treatment works as effectively as possible. Since this medicine is injected directly into a vein, food does not affect how it is absorbed, but eating light meals before your appointment and staying well-hydrated can help prevent stomach upset.

While taking this medicine, you may experience common side effects like mild nausea, temporary fatigue, or low blood cell counts. However, you must contact your doctor immediately if you experience more serious issues, such as a high fever, severe shivering, sudden chest pain, or painful burning at the injection site.

Before starting, you must tell your doctor if you have a history of liver damage, lung problems, or nerve disorders. Do not take this if you have a severely weakened immune system, very low white blood cell levels, or a serious active infection.

This medicine can interact with certain other prescriptions, live vaccines, and alcohol, which may increase the risk of severe infections or worsen liver strain. If you are pregnant, breastfeeding, or an older adult, consult your doctor or pharmacist, as special precautions or alternative options will be required.

Uses of Vinbicel 50Mg/5Ml Injection

Vinbicel 50Mg/5Ml Injection may be prescribed to treat the following types of cancer:

  • Non-small cell lung cancer: Vinbicel 50Mg/5Ml Injection helps by targeting and disrupting the division of rapidly growing lung cancer cells, slowing or stopping the spread of the tumour.
  • Advanced breast cancer: In cases where breast cancer has spread to other parts of the body, Vinbicel 50Mg/5Ml Injection helps shrink tumours and control the progression of the disease.

Key Benefits

Vinbicel 50Mg/5Ml Injection is a chemotherapy medicine used to treat certain cancers, including non-small cell lung cancer and breast cancer. It works by interfering with the division of cancer cells, helping slow or stop their growth.

  • Helps Control Cancer Growth: Interferes with cancer cell division, helping slow the growth and spread of susceptible tumours.
  • Helps Manage Advanced Cancer: As an injectable medicine, it can reach cancer cells throughout the body, making it useful when cancer has spread or requires systemic treatment.
  • May Relieve Cancer-Related Symptoms: By helping control tumour growth, it may reduce symptoms caused by the tumour, such as pain, coughing, or breathing difficulty, depending on the location and extent of the cancer.
  • Supports Disease Control: Helps stabilise the disease and may delay further progression when used as part of an appropriate chemotherapy regimen.
  • Forms Part of Combination Cancer Therapy: May be used alone or alongside other anticancer medicines, depending on the type and stage of cancer and the treatment plan prescribed by the oncologist.
Side effects of Vinbicel 50Mg/5Ml Injection
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
  • Injection site reaction can include numbness or redness.
  • Get a physical examination, follow your doctor's instructions, if it worsens or gets swollen.
  • Apply cold compress for pain relief.
  • Practice good hygiene and keep the injection site away from heat and pressure.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.

Directions for Use

  • Follow your doctor’s instructions on the dosage and timing of this medication.
  • Vinbicel 50Mg/5Ml Injection will be administered in a hospital setting under the supervision of a physician qualified by training and experience to administer cancer chemotherapeutic agents.
  • Do not self-administer.

How Vinbicel 50Mg/5Ml Injection Works

Vinbicel 50Mg/5Ml Injection contains vinorelbine. It belongs to a class of medicines known as microtubule inhibitors. Inside your body, cells rely on a microscopic structural skeleton made of proteins to divide and multiply. Vinbicel 50Mg/5Ml Injection binds to these proteins, preventing them from assembling properly. Without this structure, cancer cells cannot complete the process of division and eventually die. Because cancer cells divide much faster than normal cells, they are more sensitive to this blocking effect. This disruption helps control the spread of the disease while limiting damage to healthy cells.
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Alcohol

Consult your doctor

It is not known if alcohol affects Vinbicel 50Mg/5Ml Injection. Please consult your doctor.

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Pregnancy

Unsafe

Do not use Vinbicel 50Mg/5Ml Injection if you are pregnant or think you may be pregnant. Consult the doctor immediately if you become pregnant during treatment with Vinbicel 50Mg/5Ml Injection.

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Breast Feeding

Unsafe

Do not take Vinbicel 50Mg/5Ml Injection if you are breastfeeding. Breastfeeding must be discontinued if treatment with Vinbicel 50Mg/5Ml Injection is necessary.

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Driving

Caution

In a few people, Vinbicel 50Mg/5Ml Injection may cause dizziness or lightheadedness. Do not drive or operate heavy machinery if you experience these symptoms.

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Liver

Caution

If you have a history of liver disease, inform your doctor before receiving Vinbicel 50Mg/5Ml Injection. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Kidney

Consult your doctor

If you have a history of kidney diseases, inform your doctor before receiving Vinbicel 50Mg/5Ml Injection.

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Children

Unsafe

Vinbicel 50Mg/5Ml Injection is not recommended for children below 18 years as safety and effectiveness have not been established.

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Heart

Consult your doctor

Please inform your doctor if you have any pre-existing heart problems before using Vinbicel 50Mg/5Ml Injection. Your doctor will prescribe Vinbicel 50Mg/5Ml Injection if the benefits outweigh the risk.

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Geriatrics

Consult your doctor

Please consult a doctor before administering Vinbicel 50Mg/5Ml Injection to geriatric patients. Your doctor will prescribe Vinbicel 50Mg/5Ml Injection if the benefits outweigh the risks.

What if I have taken an overdose of Vinbicel 50Mg/5Ml Injection

Because your dosage is carefully calculated and given by trained medical professionals, an overdose is extremely rare. In the unlikely event of an accidental overdose, it can cause severe bone marrow suppression, raising your risk of serious infections and bleeding. Seek immediate medical attention or emergency care if you suspect an administration error has occurred.

Diet & Lifestyle Advise

  • Stay well-hydrated: Drink plenty of water (8 to 10 glasses daily) to help your body process and clear the medication and avoid dehydration.
  • Eat small, frequent meals: Consuming five or six small, light meals throughout the day instead of three large ones can help you manage nausea and maintain your energy levels.
  • Manage bowel movements: Eat high-fibre foods, such as whole grains, fruits, and vegetables, to prevent constipation, which is a common side effect of this class of medication.
  • Protect your immune system: Wash your hands frequently with soap and water, and avoid crowded places or close contact with individuals who are sick, as this medicine temporarily lowers your white blood cell count.
  • Use a soft-bristled toothbrush: This helps prevent bleeding and irritation in your gums, which can be sensitive during chemotherapy.
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How Soon It Starts Working

The time required for Vinbicel 50Mg/5Ml Injection to start to work: The time required for Vinbicel 50Mg/5Ml Injection to show its action is not clinically established. The time for which the effects of Vinbicel 50Mg/5Ml Injection last: The duration of action for Vinbicel 50Mg/5Ml Injection is not clinically established.

What if you forget to take Vinbicel 50Mg/5Ml Injection

Since this medicine is given in a clinical setting by a healthcare professional, it is highly unlikely that you will miss a dose on your own. However, if you miss or must reschedule your clinic appointment, contact your doctor or oncology clinic immediately to set up a new appointment. Keeping your treatment schedule consistent is critical for the success of your therapy.

Storage

• Vials of Vinbicel 50Mg/5Ml Injection must be stored in a refrigerator between 2°C and 8°C (36°F to 46°F).
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Keep Refrigerated. Do not freeze.

Drug Warnings

  • Watch the injection site: Tell your nurse immediately if you feel any burning, stinging, coldness, or pain at the injection site during your infusion. This could indicate the medicine is leaking out of the vein, which requires instant medical attention.
  • Monitor your blood counts: Attend all scheduled appointments for blood tests, as your doctor needs to check your white blood cell levels before each dose to ensure it is safe to proceed.
  • Avoid live vaccines: Do not receive live vaccines (such as yellow fever or MMR) while undergoing treatment, as your immune system is temporarily weakened and may not protect you safely.
  • Use effective birth control: Both male and female patients must use highly reliable birth control during treatment and for several months afterward to prevent pregnancy, as this medicine can harm an unborn baby.
  • Check the solution: If you are a healthcare professional or managing prep, always inspect the vial before use; the solution should be clear and colourless to pale yellow, and should not contain any visible particles.

Drug-Drug Interactions

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Inform your doctor about all medicines you are taking before receiving Vinbicel 50Mg/5Ml Injection, particularly the following:

  • Strong CYP3A4 inhibitors (like ketoconazole or clarithromycin): May increase the concentration of Vinbicel 50Mg/5Ml Injection in your blood, raising the risk of severe side effects like low blood cell counts.
  • Strong CYP3A4 inducers (like rifampicin or phenytoin): May lower the levels of Vinbicel 50Mg/5Ml Injection in your body, reducing the effectiveness of your cancer treatment.
  • Other bone marrow suppressants: Can increase the risk of severe infections and bleeding when taken together.

Drug-Drug Interactions

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How does the drug interact with Vinbicel 50Mg/5Ml Injection:
When Vinbicel 50Mg/5Ml Injection is taken with Clarithromycin, it can cause a decrease in the metabolism of Vinbicel 50Mg/5Ml Injection.

How to manage the interaction:
Although taking Clarithromycin and Vinbicel 50Mg/5Ml Injection together can evidently cause an interaction, it can be taken if your doctor has suggested it. If you're having any of these symptoms like constipation, stomach pain, or difficulty peeing, it's important to let your doctor know. They can recommend other options that won't cause these problems. You should also contact your doctor right away if you notice any numbness, weakness, trouble walking, or hearing loss. Other symptoms like seizures, bleeding, fatigue, or fever should also be reported to your doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Vinbicel 50Mg/5Ml Injection:
Combining Cladribine with Vinbicel 50Mg/5Ml Injection can increase the risk and severity of developing serious infections.

How to manage the interaction:
Taking Cladribine with Vinbicel 50Mg/5Ml Injection together can possibly result in an interaction, but it can be taken if your doctor has advised it. If you have any of these symptoms, it's important to contact a doctor right away. These symptoms include infection, fever, chills, diarrhea, sore throat, muscle aches, difficulty breathing, weight loss, and pain or burning when you pee. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Vinbicel 50Mg/5Ml Injection:
When Etanercept is used with Vinbicel 50Mg/5Ml Injection, the likelihood or severity of infection may increase.

How to manage the interaction:
Although taking Etanercept and Vinbicel 50Mg/5Ml Injection together can cause an interaction, it can be taken if a doctor has suggested it. However, if you develop fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Vinbicel 50Mg/5Ml Injection:
Combining posaconazole and Vinbicel 50Mg/5Ml Injection can raise the levels of Vinbicel 50Mg/5Ml Injection in the blood and increase its effects.

How to manage the interaction:
Although using Posaconazole and Vinbicel 50Mg/5Ml Injection together can possibly result in an interaction, they can be taken together if advised by your doctor. However, contact your doctor if you experience constipation, abdominal pain or bloating, difficulty urinating, numbness or tingling in hands and feet, muscle weakness, difficulty walking, seizures, unusual or excessive bleeding, easy bruising, paleness, fatigue, fainting, fever, chills, sore throat, or other flu-like symptoms. Do not stop taking any medications without consulting a doctor.
How does the drug interact with Vinbicel 50Mg/5Ml Injection:
When Vinbicel 50Mg/5Ml Injection and Infliximab are taken together, can lead to or increase the risk or severity of developing serious infections.

How to manage the interaction:
Taking Infliximab with Vinbicel 50Mg/5Ml Injection together can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience symptoms of fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in sputum, weight loss, red or inflamed skin, body sores, and pain or burning during urination, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip

Certain foods and beverages may affect how Vinbicel 50Mg/5Ml Injection is processed in the body:

  • Grapefruit and grapefruit juice: May interfere with how your liver processes Vinbicel 50Mg/5Ml Injection, leading to higher levels of the drug in your body and a greater risk of toxic side effects.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[CHEMOTHERAPY]

FAQs

Vinbicel 50Mg/5Ml Injection is used to treat Non-small cell lung cancer and breast cancer.
Vinbicel 50Mg/5Ml Injection works by stopping or slowing the growth of cancer cells in the body.
Use effective contraception and avoid fathering a child during treatment with Vinbicel 50Mg/5Ml Injection and four months after the end of the treatment. Discuss with the doctor about sperm conservation prior to treatment with Vinbicel 50Mg/5Ml Injection, as it may alter your fertility.
Vinbicel 50Mg/5Ml Injection may cause a severe decrease in white blood cells in the bone marrow. This might increase the risk of developing serious infections. Your doctor may advise regular tests to check the number of white blood cells in your body. Consult the doctor immediately if you experience fever, cough, congestion, sore throat or other signs of infection.
Vinbicel 50Mg/5Ml Injection may cause constipation. Consult your doctor if you experience constipation; the doctor may advise about changing your diet or using medicines to prevent/treat constipation.
Vinbicel 50Mg/5Ml Injection is a vesicant. It can cause injection site reactions and extravasation hazards. These can be reduced by shortening the infusion time and flushing with IV fluid.
Yes, Vinbicel 50Mg/5Ml Injection is effective in the treatment of non-small cell lung cancer and breast cancer. However, its effectiveness may vary from person to person.
Generally, Vinbicel 50Mg/5Ml Injection is administered intravenously by a doctor with experience in using chemotherapy medications. Do not self-administer.
Vinbicel 50Mg/5Ml Injection may cause hair loss. If you experience hair loss while on treatment with Vinbicel 50Mg/5Ml Injection consult your doctor.
The common side effects of Vinbicel 50Mg/5Ml Injection may include nausea, vomiting, constipation, injection site reactions, bleeding gums, constipation, cough, and stomach pain or tenderness. Do not be reluctant to talk with your doctor if any side effects persist or worsen.
You can usually receive a standard, inactive flu shot, but you must avoid live vaccines during your treatment because your immune system is weakened. Talk to your doctor before getting any vaccines.
Tell the nurse administering the injection immediately if you feel any burning, stinging, or pain, as this could mean the medicine is leaking from the vein. Talk to your doctor if pain continues after your appointment.
Many people can drive, but if you experience side effects like dizziness, severe fatigue, or numbness in your hands and feet, you should avoid driving. Talk to your doctor to see what is safe for you.
It is best to avoid or limit alcohol during your treatment, as alcohol can worsen side effects like nausea and put extra strain on your liver. Talk to your doctor for personalised advice.
A cycle usually lasts 3 to 4 weeks, with the medicine given once a week followed by a rest period, but your exact schedule depends on your body's response. Talk to your doctor about your treatment plan.

Disclaimer

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Country of origin

India

Manufacturer/Marketer address

Plot No 264, Patrika Nagar Madhapur, Hitech City Hyderabad, Telangana India - 500081
Other Info - VIN0212
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