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  3. Vfend 200mg Injection

Vfend 200mg Injection, Pack of 1 Injection
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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
Vfend 200mg Injection is used to treat a broad range of fungal infections. It contains 'Voriconazole' that kills or prevents fungus by inhibiting an enzyme in fungi responsible for its normal fat metabolism, thereby interfering with the fungal cell membrane formation. As a result, fungal cells get killed, or their growth is minimized. Common side effects of Vfend 200mg Injection are injection site reactions, peripheral oedema, headache, diarrhoea, vomiting, abdominal pain, chest pain, nausea, fever, anxiety, insomnia, confusion, weakness, tingling sensation, sleepiness, dizziness, irregular heartbeats, low blood pressure, stomach upset, constipation, rashes, itchiness, red skin, back pain and chills.
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Composition :

VORICONAZOLE-200MG

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Vfend 200mg Injection

Vfend 200mg Injection belongs to the class of medicines known as 'antifungals' used to treat a broad range of fungal infections. A fungal infection is caused when a fungus invades and affects any body part, including the mouth, throat, oesophagus, lungs, bladder, genital area and blood.

Vfend 200mg Injection contains 'Voriconazole' that kills or prevents fungus by inhibiting an enzyme in fungi responsible for its normal fat metabolism, thereby interfering with the fungal cell membrane formation. As a result, fungal cells get killed, or their growth is minimized.

Vfend 200mg Injection will be administered by a qualified healthcare professional. In some cases, you may experience certain common side effects, such as injection site reactions, peripheral oedema, headache, diarrhoea, vomiting, abdominal pain, chest pain, nausea, fever, anxiety, insomnia, confusion, weakness, tingling sensation, sleepiness, dizziness, irregular heartbeats, low blood pressure, stomach upset, constipation, rashes, itchiness, red skin, back pain and chills. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Before taking Vfend 200mg Injection, let your doctor know about your medical condition, sensitivities, and medications. Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Vfend 200mg Injection may affect your ability to drive or operate machinery; thus, avoid driving or using machinery.

Uses of Vfend 200mg Injection

Treatment of Fungal infections

Directions for Use

• Your doctor will determine the dosage and frequency depending on your condition.• Vfend 200mg Injection will be administered by a healthcare professional.• Do not self-administer.

Medicinal Benefits

Vfend 200mg Injection belongs to the class of medicines known as 'antifungal agents', used to treat a broad range of fungal infections, including aspergillosis (a disease caused by Aspergillus), candidiasis (fungal infection caused by yeast), coccidioidomycosis (an infection caused by the fungus Coccidioides), histoplasmosis (an infection caused by a fungus called Histoplasma), and penicilliosis (a disease caused by the fungus Talaromyces marneffei). It also effectively treats CNS fungal infections transmitted by epidural injection of contaminated steroids. On the other hand, it can prevent fungal infections in people undergoing bone marrow transplants. Vfend 200mg Injection works by killing or preventing fungi or yeast by inhibiting an enzyme in fungi responsible for its normal fat metabolism, thereby interfering with the fungal cell membrane formation. As a result, fungal cells get killed, or their growth is minimized.

How Vfend 200mg Injection Works

Vfend 200mg Injection contains 'Voriconazole' that kills or prevents fungus by inhibiting an enzyme in fungi responsible for its normal fat metabolism, thereby interfering with the fungal cell membrane formation. As a result, fungal cells get killed, or their growth is minimized.

Storage

• Store in a cool and dry place away from sunlight.
• Keep Vfend 200mg Injection out of the sight and reach of children.
• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Vfend 200mg Injection
  • Your doctor may recommend regular liver function tests (LFT) to monitor liver enzyme levels.
  • To support your liver, eat a healthy diet with lots of fruits, vegetables, lean proteins, and healthy fats.
  • Avoid eating processed meats, sugary foods, and unhealthy fats.
  • Limit your alcohol consumption, since too much can worsen liver function and contribute to high levels of Alkaline Phosphatase (ALP).
  • Stay active with regular exercise, drink plenty of water, and try to avoid harmful chemicals that can damage your liver.
  • Quit smoking to lower the risk of elevated ALP levels.
  • Increased creatinine levels must be corrected immediately with the help of a doctor.
  • Reduce strenuous activities that can lead to muscle breakdown and production of creatinine.
  • Sleep for 7-8 hours per night to assist your body in repairing and rebuilding tissue.
  • Manage your blood pressure by implementing changes in lifestyle like losing weight, reducing stress and exercising regularly.
  • Avoid smoking and drinking alcohol.
  • Skin rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Eat more potassium-rich foods, like bananas, leafy greens, sweet potatoes, avocados, and nuts/seeds.
  • Choose potassium-fortified foods such as orange juice and sports beverages.
  • Limit potassium-depleting foods like caffeine, processed foods, and sugary drinks.
  • Exercise regularly, like walking or yoga, to help maintain potassium balance.
  • Inform your doctor if hypokalemia doesn't improve or worsen despite treatment.

What if I have taken an overdose of Vfend 200mg Injection

As Vfend 200mg Injection is a parenteral formulation administered by experienced medical staff, the chance of overdose may be less. However, if you think there has been an overdose or experiencing any adverse events, get medical care right away.

Drug Warnings

Inform your doctor about your medical conditions, sensitivities, and medications you are using. And also, let your doctor know if you are pregnant, planning to become pregnant, or breastfeeding. Women of childbearing potential should always use effective contraception during treatment. Please inform your doctor if you are suffering from a heart problem like an irregular heartbeat, slow heart rate or abnormality in ECG (electrocardiogram), QT prolongation, or if you have hereditary intolerance for galactose, Lapp lactase deficiency, or glucose-galactose malabsorption. Vfend 200mg Injection may affect your ability to drive or operate machinery; thus, avoid driving or using machinery.

Drug-Drug Interactions

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VoriconazoleErgotamine
Critical
VoriconazolePhenobarbital
Critical

Drug-Drug Interactions

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VoriconazoleErgotamine
Critical
How does the drug interact with Vfend 200mg Injection:
The serum concentration of Ergometrine can be increased when it is combined with Vfend 200mg Injection.

How to manage the interaction:
Taking Ergotamine with Vfend 200mg Injection is not recommended, please consult your doctor before taking it.
VoriconazolePhenobarbital
Critical
How does the drug interact with Vfend 200mg Injection:
Using Vfend 200mg Injection together with Phenobarbital may significantly reduce the blood levels of Vfend 200mg Injection.

How to manage the interaction:
Taking Vfend 200mg Injection with Phenobarbital is not recommended, consult a doctor before taking it. Do not stop using any medications without talking to a doctor.
VoriconazoleConivaptan
Critical
How does the drug interact with Vfend 200mg Injection:
Using Conivaptan together with Vfend 200mg Injection may significantly increase the blood levels and effects of conivaptan.

How to manage the interaction:
Taking Vfend 200mg Injection with Conivaptan is not recommended, please consult your doctor before taking it. Call a doctor if you experience difficulty swallowing, trouble speaking, trouble controlling body movements. Do not stop using any medications without talking to a doctor.
VoriconazoleRitonavir
Critical
How does the drug interact with Vfend 200mg Injection:
When Vfend 200mg Injection is taken with Ritonavir, the amount of Vfend 200mg Injection in the blood may decrease.

How to manage the interaction:
Taking Vfend 200mg Injection with Ritonavir is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any unusual symptoms contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
VoriconazolePimozide
Critical
How does the drug interact with Vfend 200mg Injection:
Using Dronedarone together with Dasatinib can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Vfend 200mg Injection with Pimozide is not recommended, please consult a doctor before taking it. You should seek immediate medical attention if you develop dizziness, shortness of breath, or heart palpitations. Do not discontinue any medicatio0n without consulting a doctor.
VoriconazoleSimvastatin
Critical
How does the drug interact with Vfend 200mg Injection:
Taking Vfend 200mg Injection and Simvastatin can increase the blood levels and effects of Simvastatin. This can increase the risk of side effects (liver damage and rhabdomyolysis - involves the breakdown of skeletal muscle tissue).

How to manage the interaction:
Taking Vfend 200mg Injection and Simvastatin together is not recommended as it can lead to an interaction, but it can be taken if a doctor advises. However, if you experience muscle pain, fever or dark-colored urine, vomiting, and yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
VoriconazoleEfavirenz
Critical
How does the drug interact with Vfend 200mg Injection:
Coadministration of Vfend 200mg Injection with Efavirenz can alter the blood levels and effects of both medications.

How to manage the interaction:
Taking Vfend 200mg Injection with Efavirenz can be taken if a doctor has advised it. Contact a doctor if you experience vomiting, dizziness, difficulty concentrating. Do not discontinue any medications without consulting a doctor.
VoriconazoleVoclosporin
Critical
How does the drug interact with Vfend 200mg Injection:
Using Voclosporin together with Vfend 200mg Injection may significantly increase the blood levels of Voclosporin.

How to manage the interaction:
Taking Vfend 200mg Injection with Voclosporin is not recommended, please consult a doctor before taking it. Do not stop using any medications without talking to a doctor.
VoriconazoleRanolazine
Critical
How does the drug interact with Vfend 200mg Injection:
Co-administration of Ranolazine together with Vfend 200mg Injection may significantly increase the blood levels and effects of Ranolazine.

How to manage the interaction:
Taking Ranolazine with Vfend 200mg Injection together can result in an interaction, but it can be taken if a doctor has advised it. Consult a doctor if you experience dizziness, or fast or pounding heartbeats. Do not discontinue any medications without consulting a doctor.
VoriconazoleSirolimus
Critical
How does the drug interact with Vfend 200mg Injection:
Coadministration of Sirolimus and Vfend 200mg Injection can increase blood levels and side effects of Vfend 200mg Injection.

How to manage the interaction:
Taking Vfend 200mg Injection with Sirolimus is generally avoided as it can result in an interaction, please consult a doctor before taking it. Contact a doctor if you experience nausea, fever, abdominal pain, or yellowing of the skin or eyes. Do not stop using any medication without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • In wet places such as changing rooms and gym showers, don’t walk barefoot to prevent fungal infections.
  • Do not scratch the affected skin, as it can spread the infection to other body parts.
  • Avoid sharing towels, combs, bedsheets, shoes or socks with others.
  • Wash your bedsheets and towels regularly.
  • It is advisable to follow a candida diet during fungal infections. This diet excludes sugar, gluten, certain dairy products, and alcohol. Switch to low-sugar fruits, non-starchy vegetables and gluten-free foods. A very-high sugar or high-carbohydrate diet may increase the count of Candida in some people.

Habit Forming

No

Therapeutic Class

ANTIFUNGALS

Vfend 200mg Injection Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Consult your doctor

It is not known if alcohol affects Vfend 200mg Injection. Please consult your doctor.

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Pregnancy

Caution

Vfend 200mg Injection is generally not recommended in pregnancy. Your doctor may prescribe this medicine if the benefit to the mother outweighs the potential risk to the fetus.

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Breast Feeding

Caution

If you are breastfeeding, please inform your doctor. It is not known if Vfend 200mg Injection passes into breastmilk. Your doctor may advise you to stop breastfeeding before starting the treatment with Vfend 200mg Injection.

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Driving

Unsafe

Vfend 200mg Injection may affect your ability to drive or operate machinery; thus, avoid driving or using machinery.

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Liver

Caution

Inform your doctor if you have liver problems before receiving Vfend 200mg Injection.

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Kidney

Caution

Inform your doctor if you have kidney problems before receiving Vfend 200mg Injection.

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Children

Caution

Your doctor may prescribe this medicine if the benefits outweigh the risks.

Have a query?

FAQs

Vfend 200mg Injection is used to treat Fungal infections.

Vfend 200mg Injection contains Voriconazole that kills or prevents fungus by inhibiting an enzyme in fungi responsible for its normal fat metabolism, thereby interfering with the fungal cell membrane formation. As a result, fungal cells get killed, or their growth is minimized.

Vfend 200mg Injection can also prevent fungal infections in people undergoing bone marrow transplants.

Vfend 200mg Injection may not be suitable in patients with known hypersensitivity to any of the components present in Vfend 200mg Injection; or with a hereditary intolerance for galactose, Lapp lactase deficiency, or glucose-galactose malabsorption.

You can take Vfend 200mg Injection with contraceptive pills. However, some studies show a chance of an increase in the body's hormonal levels when you take Vfend 200mg Injection with a combined pill. Seek your doctor's advice if any side effects occur.

Yes, fungal infection is a contagious skin condition that spreads from one person to another through direct skin-to-skin contact or by contact with contaminated soil or surfaces and infected animals. Therefore, it is recommended to avoid close direct contact until the infection is clear and avoid sharing things with the infected person, as it can also spread the infection.

Vfend 200mg Injection can use women of childbearing potential; however, they must always use effective contraception during treatment.

Country of origin

India

Manufacturer/Marketer address

SUN HOUSE, CTS No. 201 B/1, Western Express Highway, Goregaon (E), Mumbai 400063
Other Info - VFE0002

Disclaimer

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Santoshini Reddy GDoctor badge

Reviewed By

Santoshini Reddy G

M Pharmacy

Last Updated

Jul 18, 2025 | 9:23 AM IST

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Reference

  1. https://labeling.pfizer.com/ShowLabeling.aspx?id=12292
  2. https://www.ikrispharmanetwork.com/voriconazole-200mg/

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