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Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Vertistar Plus 8mg Tablet is used in the treatment of Meniere's disease (a disorder of the inner ear) and its symptoms, including dizziness (vertigo), ringing in the ears (tinnitus), feeling sick (nausea), and difficulty in hearing. It contains Betahistine and Domperidone. Betahistine works by enhancing the blood flow to the affected part of the ear and reducing the amount of fluid in the inner ear. Domperidone prevents nausea and vomiting symptoms by blocking specific receptors (like dopamine and serotonin) that stimulate the vomiting centre in the brain. It also increases the upper gastrointestinal tract's motility and helps decrease stomach emptying time. It may cause side effects such as indigestion (acid reflux), bloating or mild stomach ache, headache, and dry mouth. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Manufacturer/Marketer :

Mankind Pharma Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Vertistar Plus 8mg Tablet

Vertistar Plus 8mg Tablet comes under the category of medications called 'antihistamine anti-vertigo medication,' primarily indicated in the treatment of Meniere’s disease (a disorder of the inner ear) and its symptoms, including dizziness (vertigo), ringing in the ears (tinnitus), feeling sick (nausea), and difficulty in hearing and vomiting (being sick) in adults and adolescents 12 years or older. Besides this, it also helps in the treatment of indigestion.

Vertistar Plus 8mg Tablet consists of Betahistine and Domperidone. Betahistine enhances blood flow to the affected part of the ear and reduces the amount of fluid in the inner ear. Domperidone prevents nausea and vomiting symptoms by blocking specific receptors (like dopamine and serotonin) that stimulate the vomiting centre in the brain. It also increases the upper gastrointestinal tract's motility and helps decrease stomach emptying time.

Take Vertistar Plus 8mg Tablet as prescribed. Vertistar Plus 8mg Tablet may cause some unpleasant effects, including indigestion (acid reflux), bloating or mild stomachache, and headache. Most of the undesirable effects caused by this medicine do not require medical attention and will go away in a couple of days. However, if the side effects worsen with time or do not pass in a couple of days, one should seek medical help.

Avoid using Vertistar Plus 8mg Tablet if you are allergic to it. Consult your doctor before taking Vertistar Plus 8mg Tablet if you have asthma, a stomach ulcer, a skin rash, or low blood pressure. Vertistar Plus 8mg Tablet is not recommended for children under 18 years. A person should tell their doctor about the medicines and herbal and non-herbal products they are using. Do not consume Vertistar Plus 8mg Tablet if you are hypersensitive to any components present in Vertistar Plus 8mg Tablet . Before taking the Vertistar Plus 8mg Tablet , inform your doctor if you suffer from liver or kidney problems. If a person is pregnant, breastfeeding, or planning to be pregnant, then they can only take this medicine if prescribed by the doctor. Also, tell the doctor if you have had an allergic reaction to Betahistine or any other medicines in the past.

Uses of Vertistar Plus 8mg Tablet

Vertistar Plus 8mg Tablet is used in the treatment of Meniere&#039;s disease (disorder of the inner ear), dizziness (vertigo), ringing in the ears (tinnitus), loss of hearing, feeling sick (nausea), and vomiting. The detailed uses of Vertistar Plus 8mg Tablet are as follows:<br/>• Treatment of Meniere's Disease: Vertistar Plus 8mg Tablet treats Meniere's disease by reducing vertigo episodes, relieving spinning sensations, and improving balance, ultimately lowering the risk of falls.<br/>• Inner Ear Circulation: Vertistar Plus 8mg Tablet improves inner ear circulation by enhancing blood flow and reducing fluid buildup.<br/>• Tinnitus: Vertistar Plus 8mg Tablet alleviates tinnitus symptoms by decreasing ringing or other sounds in the ears, improving the quality of life.<br/>• Nausea and Vomiting: Vertistar Plus 8mg Tablet manages nausea and vomiting by acting on the brain's vomiting center and enhancing stomach movement, reducing discomfort and dehydration risk.<br/>

Directions for Use

• Vertistar Plus 8mg Tablet can be taken with or without food.• Follow your doctor's instructions on the dosage and timing of this medication.• Swallow Vertistar Plus 8mg Tablet as a whole with a glass of water.• Do not break, chew or crush Vertistar Plus 8mg Tablet .

Medicinal Benefits

Vertistar Plus 8mg Tablet is indicated to treat symptoms such as ringing in your ears (tinnitus), dizziness, vertigo, loss of balance, and hearing loss associated with Meniere's disease (an inner ear disorder).  Vertistar Plus 8mg Tablet works by increasing the blood flow to your brain and lowering the extra pressure in the inner ear. By easing down the symptoms associated with Meniere's disease, this drug helps people live their everyday lives. Domperidone is a dopamine antagonist that helps by blocking specific vomiting-inducing receptors in the brain. Vertistar Plus 8mg Tablet also acts as a prokinetic agent that increases the upper gastrointestinal tract's motility and decreases gastric emptying time. Domperidone is occasionally used to boost milk production. If you're experiencing difficulty nursing, your doctor may prescribe it if nothing else has helped.

How Vertistar Plus 8mg Tablet Works

Vertistar Plus 8mg Tablet consists of Betahistine and Domperidone. Betahistine works by enhancing the blood flow to the affected part of the ear and also by reducing the amount of fluid in the inner ear. Domperidone prevents nausea and vomiting symptoms by blocking certain receptors (like dopamine and serotonin) that stimulate the vomiting centre (chemoreceptor trigger zone “CTZ”) located in the brain. It also acts as a prokinetic agent that increases the upper gastrointestinal tract's motility and helps decrease stomach emptying time.

Storage

• Store in a cool and dry place away from sunlight.• Keep Vertistar Plus 8mg Tablet out of the sight and reach of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of Vertistar Plus 8mg Tablet

Please do not take more than the prescribed dose of Vertistar Plus 8mg Tablet , as it may cause an overdose. The symptoms of overdose include stomach pain, nausea, sleepiness, fast heart rate, low blood pressure, bronchospasm (shortness of breath with a feeling of suffocation) and oedema (accumulation of fluids in the tissues). After taking very high doses, seizures (fits) can occur. If you suspect you have taken an overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Vertistar Plus 8mg Tablet is not allowed in patients with porphyria and should be used cautiously in patients with bronchial asthma. This medication is not allowed to be used in children and persons who have galactose intolerance. Vertigo, tinnitus, and hearing loss are common signs of Meniere's syndrome that can harm a person's ability to drive or operate any machine. Do not consume Vertistar Plus 8mg Tablet if you are allergic to any components present in Vertistar Plus 8mg Tablet . Before taking the Vertistar Plus 8mg Tablet , contact your doctor if you suffer from liver or kidney problems (kidney function impairment or failure). Prolonged intake of Vertistar Plus 8mg Tablet may be associated with an increased risk of heart rhythm disorder (arrhythmia) and cardiac arrest (heart attack). This risk may be more likely in the elderly (those over 60) or those taking doses higher than 30 mg daily. If you experience heart rhythm disorders like palpitations, trouble breathing, or loss of consciousness after taking the Vertistar Plus 8mg Tablet , immediately contact your doctor. This medicine can cause mild stomach discomfort, so taking it with food can help to reduce stomach problems. Pregnant or breastfeeding females should consult with the doctor before taking this drug, as the use of this medicine is only allowed in such cases when the benefits outweigh the risks.

Drug-Drug Interactions

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DomperidoneToremifene
Severe
DomperidoneNefazodone
Severe

Drug-Drug Interactions

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DomperidoneToremifene
Severe
How does the drug interact with Vertistar Plus 8mg Tablet:
Coadministration of Vertistar Plus 8mg Tablet with Toremifene can Increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Vertistar Plus 8mg Tablet and Toremifene together can cause an interaction, it can be taken if your doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.
DomperidoneNefazodone
Severe
How does the drug interact with Vertistar Plus 8mg Tablet:
Coadministration of Vertistar Plus 8mg Tablet with Nefazodone can increase the blood levels of Vertistar Plus 8mg Tablet.

How to manage the interaction:
There may be a possibility of interaction between Vertistar Plus 8mg Tablet and Nefazodone, but it can be taken if prescribed by a doctor. In case you experience any side effects like swelling of the ankles or feet, unusual tiredness, redness, changes in menstrual ability, contact a doctor. It is recommended to do this to ensure your heart stays healthy. Do not stop using any medications without talking to a doctor.
How does the drug interact with Vertistar Plus 8mg Tablet:
Coadministration of Vertistar Plus 8mg Tablet with Cisapride can increase the blood levels of Vertistar Plus 8mg Tablet.

How to manage the interaction:
There may be a possibility of interaction between Vertistar Plus 8mg Tablet and Cisapride, but it can be taken if prescribed by a doctor. In case you experience any side effects like swelling of the ankles or feet, unusual tiredness, redness, changes in menstrual ability, contact a doctor. It is recommended to do this to ensure your heart stays healthy. Do not stop using any medications without talking to a doctor.
DomperidoneBepridil
Severe
How does the drug interact with Vertistar Plus 8mg Tablet:
Co-administration of Domeperidone and Bepridil can increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Vertistar Plus 8mg Tablet and Bepridil together can cause an interaction, it can be taken if your doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Vertistar Plus 8mg Tablet:
Coadministration of Vertistar Plus 8mg Tablet with Citalopram can Increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Vertistar Plus 8mg Tablet and Citalopram together can cause an interaction, it can be taken if your doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Vertistar Plus 8mg Tablet:
Coadministration of Vertistar Plus 8mg Tablet with Ketoconazole can Increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Vertistar Plus 8mg Tablet and Ketoconazole together can cause an interaction, it can be taken if a doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.
DomperidoneMethadone
Severe
How does the drug interact with Vertistar Plus 8mg Tablet:
Coadministration of Vertistar Plus 8mg Tablet with Methadone can Increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Vertistar Plus 8mg Tablet and Methadone together can cause an interaction, it can be taken if your doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Vertistar Plus 8mg Tablet:
Coadministration of Vertistar Plus 8mg Tablet with Clarithromycin can increase the risk of side effects.

How to manage the interaction:
There may be a possibility of interaction between Vertistar Plus 8mg Tablet and Clarithromycin, but it can be taken if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
DomperidoneHalofantrine
Severe
How does the drug interact with Vertistar Plus 8mg Tablet:
Coadministration of Vertistar Plus 8mg Tablet with Halofantrine can Increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Vertistar Plus 8mg Tablet and Halofantrine together can cause an interaction, it can be taken if your doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Vertistar Plus 8mg Tablet:
Combining Mizolastine with Vertistar Plus 8mg Tablet can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Although taking Vertistar Plus 8mg Tablet and Mizolastine together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Avoid caffeine-containing beverages (coffee, tea), spicy, deep-fried, and processed foods, carbonated drinks, and acidic foods like citrus fruits and vegetables (tomatoes).
  • Make a habit of waiting consistently for the whole day. One should not stay without eating for 4 hours. Limit alcohol consumption, as this may reduce the chances of migraines.
  • Get 8 hours of sleep, which helps the body to relax completely.
  • A person should quit tobacco or smoking as it narrows the blood vessels and affects circulation, which may result in Meniere's disease.
  • Eat a healthy low-fat diet, especially in small portions, as it will be easy to digest. Avoid over-sweet food and include more salty food, especially if you have been vomiting.
  • Also, if you like vomiting at a specific time, avoid eating your favourite food at that particular time, as your taste for that food may get turned off.
  • Include more cool beverages in your food, such as clear soups, flavoured gelatin, and carbonated beverages. When you drink with a straw, sip slowly to avoid swallowing air that may lead to gas or acidity.

Habit Forming

No

Therapeutic Class

ANTIVERTIGO DRUGS
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Alcohol

Caution

Avoid consumption of alcohol as it may worsen the side effects of Vertistar Plus 8mg Tablet .

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Pregnancy

Caution

Vertistar Plus 8mg Tablet can be used during pregnancy but only under the supervision of a physician. Your doctor will weigh the benefits and potential risks before prescribing it. Please consult your doctor.

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Breast Feeding

Caution

Vertistar Plus 8mg Tablet is not allowed to be taken during breastfeeding or if directed by the doctor as it is still under research whether this medicine passes in breast milk or not.

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Driving

Unsafe

Taking Vertistar Plus 8mg Tablet affects a person's ability to drive, so one should avoid driving.

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Liver

Caution

If you have pre-existing liver disease, inform your doctor before taking Vertistar Plus 8mg Tablet as it may worsen your condition.

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Kidney

Caution

If you have pre-existing kidney disease, inform your doctor before taking Vertistar Plus 8mg Tablet as it may worsen your condition.

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Children

Unsafe

The use of Vertistar Plus 8mg Tablet is not recommended in children and adolescents whose age is less than 18 years due to a shortage of data on safety and effectiveness.

Have a query?

FAQs

This medicine may take a couple of weeks to show any noticeable improvement. Even if a person starts feeling better, they still need to take this medicine and should not stop it without asking the doctor.

Vertistar Plus 8mg Tablet is used in the treatment of Meniere's disease, dizziness (vertigo), ringing in the ears (tinnitus), loss of hearing, feeling sick (nausea) and vomiting.

Although a person can consume alcohol while taking Vertistar Plus 8mg Tablet , but still alcohol may worsen the side effects of medicine so one should avoid taking it.

Yes, Vertistar Plus 8mg Tablet is a histamine analogue that works by improving the effect of histamine in the inner ear. At the same time, antihistamines are the drugs that work by stopping the action of histamine in the body and are prescribed for relieving the symptoms of allergy.

There is no clear evidence to suggest that taking betahistine would decrease fertility in both men and women. However, if you are trying to get pregnant, talk to your doctor before taking it.

Before taking Vertistar Plus 8mg Tablet , inform your doctor if you have any allergies, asthma, pheochromocytoma (a rare tumor of the adrenal gland), and if you have or ever had stomach ulcer.

Meniere's disease is an inner ear disorder that causes episodes of spinning (vertigo). It usually starts in one ear, but eventually it can affect both. The symptoms include hearing loss, vertigo (spinning sensation), tinnitus (ringing in the ear) and ear pressure. There is no cure for Meniere's disease yet. However, treatments can help relieve symptoms.

Vertistar Plus 8mg Tablet is effective if it is used as advised by the doctor. Use Vertistar Plus 8mg Tablet for as long as it is prescribed by the doctor. Do not discontinue Vertistar Plus 8mg Tablet early as the symptoms may return or worsen.

Meniere's disease can be triggered by smoking, stress or anxiety, fatigue (overtiredness), hormonal fluctuations, migraines, alcohol, weather changes or side effects of certain medications.

If you forget to take a dose of Vertistar Plus 8mg Tablet , take it as soon as you remember. But, if it is time for your next dose, skip the missed dose and take your regular dose. Do not take a double dose to make up for a forgotten dose.

Yes, Vertistar Plus 8mg Tablet can cause dry mouth. In case you feel excessively thirsty, please increase your fluid intake and do frequent mouth rinses.

Country of origin

India

Manufacturer/Marketer address

208, Okhla Industrial Estate, Phase III, New Delhi - 110020
Other Info - VER0210

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