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Vargesic-XT Tablet is used to treat common cold and allergic symptoms like sneezing, watery eyes or itchy/watery nose and throat. It works by blocking the action of histamine, a substance responsible for causing allergic reactions. Also, it helps shrink the blood vessels in the nasal passage, reducing a stuffy nose. Some people may experience drowsiness, nausea, fatigue, dryness in the mouth, headache, and vomiting. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Mrs. Veda Maddala , M Pharmacy
Reviewed By Dr. E Naresh Kumar , MD, MBBS
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More about the Product

Composition :

CETIRIZINE-5MG+PARACETAMOL-500MG+PHENYLEPHRINE-5MG

Manufacturer/Marketer :

Vsaar Pharma Pvt Ltd

Consume Type :

Oral

Expires on or after :

Dec-28

Return Policy :

Not Returnable

About Vargesic-XT Tablet

Vargesic-XT Tablet is a medicine designed to relieve the uncomfortable symptoms of the common cold, flu, and upper respiratory allergies. It is medically formulated to target nasal congestion, runny nose, sneezing, fever, and minor body aches. By combining multiple active ingredients into one convenient formulation, it provides comprehensive relief during seasonal illness.

To get the best results, you should take this medicine exactly as prescribed by your doctor, keeping your dosing consistent. You can take Vargesic-XT Tablet with or without food, but taking it with food may help prevent mild stomach upset. Incorporating simple changes like resting more, staying hydrated, and breathing in warm steam can also make your recovery much faster and smoother.

While taking Vargesic-XT Tablet, you might experience mild side effects like drowsiness or a dry mouth. However, you must stop taking the medicine and consult your doctor immediately if you experience serious symptoms such as severe dizziness, an irregular heartbeat, or signs of an allergic reaction. Your safety is always the priority, so never ignore unexpected body changes.

Do not take this if you have severe high blood pressure, serious blood vessel disease, or severe liver damage. It is crucial to talk to your doctor before starting this medicine if you have underlying conditions like diabetes, glaucoma, thyroid issues, or difficulty urinating due to an enlarged prostate.

This medicine can interact with other drugs, especially some antidepressants and other cold medicines, which may increase your blood pressure or cause excessive drowsiness. You should also avoid drinking alcohol while on this medication because it increases the strain on your liver. If you are pregnant, breastfeeding, or an older adult, talk to your doctor or pharmacist before taking this product to ensure it is safe for you.

 

Uses of Vargesic-XT Tablet

Your doctor may prescribe this medicine to treat several conditions, including:

  • Common Cold and Flu: Helps ease the overall discomfort of viral infections by reducing fever, relieving sore throat discomfort, and soothing body aches.
  • Nasal Congestion: Clears blocked nasal passages and sinus pressure, making it much easier to breathe comfortably.
  • Allergic Rhinitis: Controls allergy-related symptoms such as continuous sneezing, itchy nose or throat, and watery eyes.
     

Key Benefits

When taken as prescribed, this medicine offers several important benefits, including:

  • All-in-One Relief from Cold and Allergy Symptoms: It helps manage multiple symptoms together, including fever, nasal congestion, runny nose, sneezing, and watery eyes, reducing the need for multiple separate medicines.
  • Improved Breathing and Reduced Sinus Discomfort: By helping relieve nasal blockage and swelling, it supports easier breathing and reduces discomfort caused by sinus pressure and congestion.
  • Relief from Fever and Allergy-Related Symptoms: The combined action of these 3 components helps lower fever, control allergic reactions, and reduce symptoms such as sneezing and watery eyes for greater comfort.
  • Better Rest and Faster Recovery Support: By easing uncomfortable cold and allergy symptoms, Vargesic-XT Tablet helps you rest more comfortably and supports a smoother recovery process.
     
Side effects of Vargesic-XT Tablet
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.

Directions for Use

To ensure you get the maximum benefit from Vargesic-XT Tablet safely, follow these step-by-step instructions:

  • Swallow the tablet whole with a full glass of water.
  • Do not crush, chew, or break the tablet, as this can release the medication too quickly and increase the risk of side effects.
    You may take this medicine with or without food, but taking it with a meal can help if you are prone to a sensitive stomach.
  • Always follow your doctor's exact instructions regarding how often to take this medicine, and do not exceed the recommended duration of treatment.
     

How Vargesic-XT Tablet Works

Vargesic-XT Tablet works through the combined action of three distinct active ingredients that target different symptoms simultaneously. Paracetamol: This component acts as a pain reliever and fever reducer. It works by blocking chemical messengers in the brain that signal pain and regulating the body's internal thermostat to lower fever. Phenylephrine: This is a decongestant that relieves a stuffy nose. It works by narrowing the swollen blood vessels in your nasal passages, which reduces swelling, clears blockages, and improves airflow. Cetirizine: This is an antihistamine that addresses allergy symptoms. It blocks histamine, a natural substance your body releases during an allergic reaction, thereby stopping runny noses, watery eyes, and sneezing.
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Alcohol

Caution

Avoid consumption of alcohol with Vargesic-XT Tablet as it may increase drowsiness. Please consult a doctor before consuming alcohol with Vargesic-XT Tablet.

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Pregnancy

Caution

The safety of Vargesic-XT Tablet in pregnant women is unknown. Therefore, it is given to pregnant women only if the doctor thinks the benefits outweigh the risks.

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Breast Feeding

Caution

The safety of Vargesic-XT Tablet in breastfeeding mothers is unknown. Therefore, it is given to breastfeeding mothers only if the doctor thinks the benefits are greater than the risks.

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Driving

Caution

Vargesic-XT Tablet may cause drowsiness or tiredness in some people. Therefore, drive only if you are alert after taking Vargesic-XT Tablet.

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Liver

Caution

Take Vargesic-XT Tablet with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Vargesic-XT Tablet with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Caution

Vargesic-XT Tablet is not recommended for children below 12 years of age. However, please consult a doctor before giving Vargesic-XT Tablet to children.

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Heart

Unsafe

Vargesic-XT Tablet is not recommended for use in heart patients as it can lead to cardiovascular effects.

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Geriatrics

Caution

Vargesic-XT Tablet should be given with caution in elderly patients due to an increased risk of side effects. Seek medical advice before using Vargesic-XT Tablet.

What if I have taken an overdose of Vargesic-XT Tablet

An overdose of Vargesic-XT Tablet may cause unpleasant side effects. If you suspect you have taken an overdose, please consult a doctor immediately.

Diet & Lifestyle Advise

  • Stay hydrated: Drink plenty of water, warm herbal teas, or broths to help thin out mucus in your sinuses and throat.
  • Use steam therapy: Inhale steam from a warm shower or use a cool-mist humidifier to keep your nasal passages moist and reduce congestion.
  • Prioritise rest: Give your body time to heal by getting at least 7 to 8 hours of sleep per night and avoiding strenuous physical activity.
  • Avoid irritants: Stay away from secondhand smoke, strong chemical fumes, and cold drafts, which can worsen nasal swelling and trigger coughing fits.
     
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How Soon It Starts Working

The time required for Vargesic-XT Tablet to start to work: Vargesic-XT Tablet ideally shows its action within 1 hour after administration.

The time for which the effects of Vargesic-XT Tablet last: The duration of action for Vargesic-XT Tablet is unknown.

What if you forget to take Vargesic-XT Tablet

If you miss a dose of Vargesic-XT Tablet, take it as soon as you remember. However, if it is almost time for the next dose, skip the missed one and continue with your regular schedule. Do not take a double dose to make up for the missed one.

Storage

•Proper storage ensures that your medicine remains safe and effective. •Store Vargesic-XT Tablet at room temperature, ideally between 15°C and 30°C.

Drug Warnings

  • Check the Packaging Before Use: Always check the blister pack before taking Vargesic-XT Tablet. Do not use the medicine if the packaging is broken, punctured, damaged, or shows signs of tampering.
  • Avoid Driving Until You Know Its Effects: Do not drive, ride a bicycle, or operate heavy machinery until you understand how Vargesic-XT Tablet affects your alertness, as it may cause drowsiness or reduced concentration.
  • Check Other Medicines for Duplicate Ingredients: Before taking any other cough, cold, allergy, or pain relief medicines, check the label carefully to ensure they do not contain the same ingredients, such as paracetamol or decongestants, which may increase the risk of side effects.
  • Limit Caffeine Intake: Reduce consumption of caffeinated drinks such as coffee, tea, and energy drinks, as caffeine may worsen symptoms like restlessness, nervousness, or a fast heartbeat that can sometimes occur with decongestants.
  • Monitor Symptom Improvement: If symptoms do not improve within 3 to 5 days, or if fever becomes worse, stop taking Vargesic-XT Tablet and consult your doctor for further advice.
     

Drug-Drug Interactions

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Drug-Drug Interactions:

Inform your doctor if you are taking any of the following medicines, as they may interact.

  • Monoamine Oxidase Inhibitors (MAOIs): Do not take this medicine if you have taken an MAOI antidepressant within the last 14 days, as this can cause a dangerous, rapid rise in blood pressure.
  • Other Paracetamol-Containing Products: Combining these can exceed the safe daily limit, significantly increasing your risk of severe liver damage.
  • Blood Thinners: Regular, long-term use of paracetamol may increase the risk of bleeding when taken with medications like warfarin.

Drug-Food Interactions:

  • Alcohol: Avoid drinking alcohol while taking this medicine, as it increases drowsiness and elevates the risk of toxic liver damage.
  • Caffeine: High amounts of caffeine can worsen side effects like restlessness, sleep issues, or a fast heartbeat.


Drug-Disease Interactions:

Inform your doctor if you have a history of the following conditions before taking Vargesic-XT Tablet, as it may worsen your condition or cause complications.

  • Severe High Blood Pressure or Heart Disease: The decongestant component can narrow blood vessels, which may worsen these conditions.'
  • Liver Disease: Pre-existing liver conditions increase the risk of severe liver damage from paracetamol.
  • Diabetes and Thyroid Disorders: This medicine can occasionally affect blood sugar levels or interact with thyroid functions, so use with caution.

 

Cetirizine + Phenylephrine + ParacetamolSelegiline
Critical
Cetirizine + Phenylephrine + ParacetamolLinezolid
Critical

Drug-Drug Interactions

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Cetirizine + Phenylephrine + ParacetamolSelegiline
Critical
How does the drug interact with Vargesic-XT Tablet:
Co-administration of Selegiline with Phenylephrine together can raise blood pressure.

How to manage the interaction:
Taking Selegiline with Phenylephrine is not recommended, it can be taken together if prescribed by a doctor. However, consult a doctor immediately if you experience any symptoms such as severe headache, blurred vision, confusion, fits, chest pain, nausea or vomiting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, sweating, lightheadedness, and/or fainting Do not discontinue any medications without consulting a doctor.
Cetirizine + Phenylephrine + ParacetamolLinezolid
Critical
How does the drug interact with Vargesic-XT Tablet:
Taking linezolid and phenylephrine together can increase blood pressure.

How to manage the interaction:
Using linezolid and phenylephrine together is not recommended as it can lead to an interaction, it can be taken if your doctor has suggested it. If you experience any symptoms, consult the doctor immediately. Do not discontinue any medications without consulting your doctor.
Cetirizine + Phenylephrine + ParacetamolFurazolidone
Critical
How does the drug interact with Vargesic-XT Tablet:
Taking Furazolidone with Phenylephrine can cause an increase in high blood pressure.

How to manage the interaction:
Taking Furazolidone with Phenylephrine is not recommended, it can be taken if prescribed by the doctor. However, if you experience sudden and severe headache, blurred vision, confusion, seizures, chest pain, nausea or vomiting, sweating, lightheadedness, fainting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, consult the doctor immediately. It is advised to use Phenylephrine only after 14 days of stopping Furazolidone.
Cetirizine + Phenylephrine + ParacetamolTranylcypromine
Critical
How does the drug interact with Vargesic-XT Tablet:
Taking Tranylcypromine with Phenylephrine can increase the risk of high blood pressure.

How to manage the interaction:
Taking Tranylcypromine with Phenylephrine is not recommended, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience severe headache, blurred vision, confusion, seizures, chest pain, nausea or vomiting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, sweating, lightheadedness, and fainting Do not discontinue any medications without consulting a doctor.
Cetirizine + Phenylephrine + ParacetamolMethylene blue
Critical
How does the drug interact with Vargesic-XT Tablet:
Combining methylene blue and phenylephrine can cause high blood pressure.

How to manage the interaction:
Using methylene blue and phenylephrine together is not recommended as it can lead to an interaction, it can be taken if your doctor has suggested it. If you experience any symptoms like sudden and severe headache, blurred vision, confusion, seizures, chest pain, nausea or vomiting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, sweating, lightheadedness, and/or fainting, consult the doctor immediately. Do not discontinue any medications without consulting your doctor.
Cetirizine + Phenylephrine + ParacetamolSevoflurane
Critical
How does the drug interact with Vargesic-XT Tablet:
Co-administration of Phenylephrine with Sevoflurane can increase the levels of phenylephrine and lead to side effects.

How to manage the interaction:
Taking Phenylephrine with Sevoflurane is not recommended, it can be taken if prescribed by the doctor. Do not discontinue the medications without consulting a doctor.
Cetirizine + Phenylephrine + ParacetamolIsoflurane
Severe
How does the drug interact with Vargesic-XT Tablet:
Taking Phenylephrine with Isoflurane may lead to increased side effects of Phenylephrine.

How to manage the interaction:
Co-administration of Phenylephrine with Isoflurane can possibly result in an interaction, but it can be taken if a doctor has advised it. However, if you experience any unusual symptoms, consult the doctor. Do not discontinue any medications without a doctor's advice.
Cetirizine + Phenylephrine + ParacetamolMethoxyflurane
Severe
How does the drug interact with Vargesic-XT Tablet:
Co-administration of Phenylephrine with Methoxyflurane can increase the side effects of Methoxyflurane.

How to manage the interaction:
There may be a possibility of interaction between Phenylephrine and Methoxyflurane, but it can be taken if prescribed by a doctor. Do not discontinue any medications without doctor's advice.
Cetirizine + Phenylephrine + ParacetamolLomitapide
Severe
How does the drug interact with Vargesic-XT Tablet:
Co-administration of Lomitapide and Paracetamol may increase the risk of severity of liver injury.

How to manage the interaction:
Although there is a possible interaction between paracetamol and lomitapide, you can take these medicines together if prescribed by a doctor. If you experience any symptoms like fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark urine, pale stools, and/or yellowing of the skin or eyes, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
Cetirizine + Phenylephrine + ParacetamolTopiramate
Severe
How does the drug interact with Vargesic-XT Tablet:
Co-administration of Topiramate and Cetirizine can increase side effects.

How to manage the interaction:
Although there is a possible interaction between Phenylephrine and Topiramate, you can take these medicines together if prescribed by your doctor. However, if you experience any unusual symptoms, consult the doctor. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[RESPIRATORY STIMULANTS]

FAQs

Vargesic-XT Tablet is used to treat the common cold and allergic symptoms like sneezing, watery eyes or itchy/watery nose and throat.
Vargesic-XT Tablet is composed of three medicines, namely Cetirizine (antihistamine), Phenylephrine‚ (decongestant), and Paracetamol (analgesic and antipyretic). Cetirizine works by blocking the action of histamine, a substance responsible for causing allergic reactions. It helps relieve allergy symptoms such as sneezing, a runny nose, watery eyes, itching, swelling, congestion, or stiffness. Phenylephrine helps shrink the blood vessels in the nostrils and the passage and reduces stuffy noses. Paracetamol works by inhibiting the production of certain chemical messengers in the brain known as prostaglandins responsible for pain and fever.
No, you are not recommended to take Vargesic-XT Tablet with warfarin as co-administration of these two medicines may increase bleeding risk more easily. However, if you notice blood in urine or stools, dizziness, unusual bleeding or bruising, vomiting, weakness, or headache, please consult a doctor immediately. If you are supposed to use these medicines together, you are advised to contact your doctor so that the dose may be adjusted appropriately to use safely.
It is not recommended to take Vargesic-XT Tablet along with any anti-depressant medication as it contains phenylephrine, which is known to be contraindicated with anti-depressant medications, especially MAO inhibitors. Vargesic-XT Tablet should be taken at least 15 days after your last dose of antidepressants.
Yes, Vargesic-XT Tablet is known to cause nausea or vomiting. In case you are experiencing excessive nausea while consuming Vargesic-XT Tablet, speak with your doctor.
Store Vargesic-XT Tablet at room temperature, in a dry place. Keep it out of sight and reach of children.
Vargesic-XT Tablet may cause side effects like drowsiness, nausea, fatigue, dryness in the mouth, headache, and vomiting. Most of these side effects of Vargesic-XT Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
Vargesic-XT Tablet is contraindicated in people who are allergic to any of the components in Vargesic-XT Tablet. Let the doctor know if you have heart problems, stomach ulcers or thyroid problems.
No, taking a higher than the recommended dose of Vargesic-XT Tablet will not be more effective but may cause unpleasant side effects. Take Vargesic-XT Tablet as per the dose advised by the doctor.
Serious side effects associated with Vargesic-XT Tablet are allergic reactions, mouth ulcers, breathing problems, irregular heartbeat, or unexplained bleeding. Consult the doctor if you experience any of these side effects.
You should consult your doctor before taking Vargesic-XT Tablet while breastfeeding. Some of the active ingredients can pass into breast milk and may affect your baby. Talk to your doctor to evaluate the safest options for you.
No, Vargesic-XT Tablet is formulated for short-term relief of acute cold, flu, and allergy symptoms like congestion and runny nose. It is not intended to treat chronic respiratory conditions or a chronic cough.
Yes, some individuals may experience mild dizziness or drowsiness while taking Vargesic-XT Tablet. If you feel dizzy, sit or lie down, and avoid driving or handling machinery.
You should avoid taking Vargesic-XT Tablet with other pain relievers that contain paracetamol, as this can lead to an accidental overdose and severe liver damage. Always check the active ingredients of any other medication, and talk to your doctor or pharmacist if you are unsure.
This medicine is designed for short-term symptom relief. If your cold or allergy symptoms do not improve after 3 to 5 days, or if your fever worsens, stop taking it.
Yes, the antihistamine in Vargesic-XT Tablet can sometimes cause dry mouth. You can manage this by sucking on sugar-free hard candies, chewing sugar-free gum, or drinking water frequently.
You should talk to your doctor before taking Vargesic-XT Tablet if you have glaucoma. Decongestants and antihistamines can sometimes increase pressure inside the eyes, which may worsen certain types of glaucoma.
Take the missed dose as soon as you remember. If it is nearly time for your next scheduled dose, skip the missed one entirely and continue with your normal schedule. Do not take two doses at once.

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Reference

  1. Drugs.com Clinical Review Team. Paracetamol Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026]Check here
  2. CiplaMed Clinical Compendium. Alerid Colds Product Specification Guide. Mumbai, India: Cipla; 2024. [Accessed on 02 Jun. 2026]Check here
  3. National Health Service (NHS). Paracetamol For Adults - NHS Medicines Reference Guide. London, UK: NHS; 2025. [Accessed on 02 Jun. 2026]Check here
  4. MedlinePlus. A606008 Patient Information Monograph. Bethesda, MD: U.S. National Library of Medicine (NLM); 2025. [Accessed on 02 Jun. 2026]Check here
  5. Drugs.com Clinical Review Team. Cetirizine Patient Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026]Check here
  6. Citrizine Citrizine. 2014. [Accessed on 18 Apr. 2019]Check here
  7. Ikon Remedies Ikon Remedies. [Accessed on 16 Sep. 2024]Check here

Country of origin

India
Other Info - VA76765
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