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  3. Vapcar 400mg Tablet DT

Vapcar 400mg Tablet DT, Pack of 1 Tablet
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Written By ,
Reviewed By Santoshini Reddy G , M Pharmacy

Vapcar 400mg Tablet DT is used to control high phosphate levels in the body (hyperphosphataemia) in adult patients on dialysis (a blood clearance technique), patients undergoing hemodialysis (using a blood filtration machine), and patients with chronic kidney disease. It is also used for the treatment of bone disease. It contains Sevelamer, which effectively reduces excess phosphate levels in the blood, prevents the unsafe build-up of phosphate in your body and helps keep your bones strong. It may cause common side effects such as vomiting, upper abdominal pain, nausea, constipation, and diarrhoea. Let the doctor know if you are pregnant, breastfeeding, taking other medicines or have pre-existing medical conditions.

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Synonym :

SEVELAMER CARBONATE

Composition :

SEVELAMER-400MG

Manufacturer/Marketer :

Neovap Bio Pharmaceutical Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

About Vapcar 400mg Tablet DT

Vapcar 400mg Tablet DT is used to control high phosphate levels in the body (hyperphosphataemia) in adult patients on dialysis (a blood clearance technique), patients undergoing hemodialysis (using a blood filtration machine), and patients with chronic kidney disease. It is also used to prevent the development of bone disease along with other treatments like calcium and vitamin D supplements.

Vapcar 400mg Tablet DT contains sevelamer, which works by binding phosphate in the gastrointestinal tract and decreasing absorption. It effectively reduces excess phosphate levels in the blood, prevents the unsafe build-up of phosphate in your body and helps keep your bones strong.

Take Vapcar 400mg Tablet DT exactly as directed by your doctor. The common side effects of Vapcar 400mg Tablet DT are vomiting, upper abdominal pain, nausea, diarrhoea, and constipation. Most of these side effects may not require medical attention and resolve over time. However, if the side effects persist or worsen, contact your doctor.

Do not take Vapcar 400mg Tablet DT if you are allergic to any of its components, have low levels of phosphate in the blood, or have a bowel obstruction. If you are pregnant or breastfeeding, please consult your doctor before taking Vapcar 400mg Tablet DT. Keep your doctor informed about your health condition and medications to prevent any interactions/side effects.

Uses of Vapcar 400mg Tablet DT

Vapcar 400mg Tablet DT is used to control high phosphate levels in patients with kidney problems. The detailed uses of Vapcar 400mg Tablet DT are as follows:

  • Treatment of hyperphosphatemia in dialysis patients: Used to lower high blood phosphate levels in adults undergoing haemodialysis or peritoneal dialysis.
  • Management of hyperphosphatemia in non-dialysis chronic kidney disease (CKD) patients: Prescribed for patients with chronic renal disease who do not require dialysis but have elevated serum phosphorus levels (≥1.78 mmol/L).
  • Prevention of bone disorders: Used in combination with calcium and vitamin D supplements to lower the risk of bone disease caused by high phosphate levels.
  • Supports phosphate balance: Vapcar 400mg Tablet DT helps to maintain a healthy balance of minerals in the blood when the kidneys are unable to filter phosphate properly.

Directions for Use

  • Take Vapcar 400mg Tablet DT with food or as advised by your doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Check the label for directions and use as advised. Mix the recommended amount of powder using the dosing spoon in 30 mL of water, stir well, and drink it within 30 minutes.
  • Do not store the dissolved mixture for later use. Avoid mixing the contents with very hot or cold liquids.

Medicinal Benefits

Vapcar 400mg Tablet DT belongs to a group of medications called phosphate binders which is used to controls hyperphosphataemia (high blood phosphate levels) in adult patients on dialysis (a blood clearance technique), patients undergoing hemodialysis (using a blood filtration machine) or peritoneal dialysis (where the fluid is pumped into the abdomen and an internal body membrane filters the blood), and patients with chronic kidney disease. Vapcar 400mg Tablet DT contains Sevelamer, which works by binding phosphate in the gastrointestinal tract and decreasing its absorption. This lowers the phosphate concentration in the body. It effectively reduces excess phosphate levels in the blood, prevents the unsafe buildup of phosphate in your body and helps keep your bones strong.

How Vapcar 400mg Tablet DT Works

Vapcar 400mg Tablet DT contains sevelamer, which binds to phosphate in the gut and reduces its absorption. This helps lower high phosphate levels in the blood.

Storage

• Store in a cool and dry place away from sunlight.• Keep Vapcar 400mg Tablet DT out of the sight and reach of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Vapcar 400mg Tablet DT
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Here are the few steps for dealing with itching caused by drug use:
  • Report the itching to your doctor immediately; they may need to change your medication or dosage.
  • Use a cool, damp cloth on the itchy area to help soothe and calm the skin, reducing itching and inflammation.
  • Keep your skin hydrated and healthy with gentle, fragrance-free moisturizers.
  • Try not to scratch, as this can worsen the itching and irritate your skin.
  • If your doctor prescribes, you can take oral medications or apply topical creams or ointments to help relieve itching.
  • Track your itching symptoms and follow your doctor's guidance to adjust your treatment plan if needed. If the itching persists, consult your doctor for further advice.
Here are the steps to manage Joint Pain caused by medication usage:
  • Please inform your doctor about joint pain symptoms, as they may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Your doctor may prescribe common pain relievers if necessary to treat joint discomfort.
  • Maintaining a healthy lifestyle is key to relieving joint discomfort. Regular exercise, such as low-impact sports like walking, cycling, or swimming, should be combined with a well-balanced diet. Aim for 7-8 hours of sleep per night to assist your body in repairing and rebuilding tissue.
  • Applying heat or cold packs to the affected joint can help reduce pain and inflammation.
  • Please track when joint pain occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • If your joint pain is severe or prolonged, consult a doctor to rule out any underlying disorders that may require treatment.
Managing Medication-Triggered Bronchitis (Inflammation of the bronchial tubes): A Step-by-Step Guide:
  • If you experience symptoms like coughing, wheezing, chest tightness, or difficulty breathing after taking medication, seek medical attention immediately.
  • Your healthcare provider will work with you to stop the medication causing the reaction, start alternative treatments, and provide supportive therapy.
  • To manage symptoms and prevent complications, follow your doctor's advice to use inhalers or nebulizers as prescribed, practice good hygiene, avoid irritants, stay hydrated, and get plenty of rest.
  • Regularly track your symptoms and report any changes or concerns to your healthcare provider.
Here are the seven steps to manage medication-triggered Dyspnea (Difficulty Breathing or Shortness of Breath):
  • Tell your doctor immediately if you experience shortness of breath after taking medication.
  • Your doctor may adjust the medication regimen or dosage or give alternative medical procedures to minimize the symptoms of shortness of breath.
  • Monitor your oxygen levels and breathing rate regularly to track changes and potential side effects.
  • For controlling stress and anxiety, try relaxation techniques like deep breathing exercises, meditation, or yoga.
  • Make lifestyle changes, such as quitting smoking, exercising regularly, and maintaining a healthy weight.
  • Seek emergency medical attention if you experience severe shortness of breath, chest pain, or difficulty speaking.
  • Follow up regularly with your doctor to monitor progress, adjust treatment plans, and address any concerns or questions.

What if I have taken an overdose of Vapcar 400mg Tablet DT

Do not take more than the prescribed dose of Vapcar 400mg Tablet DT as it may cause an overdose. If you suspect you have taken an overdose, please consult a doctor immediately.

Drug Warnings

Do not take Vapcar 400mg Tablet DT if you are allergic to any of its components, have low levels of phosphate or have bowel obstruction. Inform your doctor if you have swallowing disorders, motility problems in the stomach or intestine, active bowel inflammation, or have undergone major surgery on your stomach or bowel. If you are pregnant or breastfeeding, consult your doctor before using Vapcar 400mg Tablet DT. Talk to your doctor if you have severe abdominal pain, stomach or intestinal disorders, or blood in the stool, as these could be symptoms of inflammatory bowel disease caused by sevelamer crystals deposited in your bowel.

Drug-Drug Interactions

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SevelamerEnoxacin
Severe
SevelamerGemifloxacin
Severe

Drug-Drug Interactions

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SevelamerEnoxacin
Severe
How does the drug interact with Vapcar 400mg Tablet DT:
Co-administration of Enoxacin and Vapcar 400mg Tablet DT can decrease the blood levels and effectiveness of Enoxacin.

How to manage the interaction:
Co-administration of Enoxacin and Vapcar 400mg Tablet DT can lead to an interaction, but it can be taken if advised by your doctor. Do not stop using any medications without a doctor's advice.
SevelamerGemifloxacin
Severe
How does the drug interact with Vapcar 400mg Tablet DT:
Gemifloxacin's efficiency can be decreased by Vapcar 400mg Tablet DT if it prevents the drug from being absorbed into the bloodstream. this is caused by the combined use of gemifloxacin and Vapcar 400mg Tablet DT.

How to manage the interaction:
Co-administration of enoxacin and Vapcar 400mg Tablet DT can lead to an interaction, but it can be taken if your doctor advises. It has been advised to separate the dosing of these medications by at least 4 hours and consult the doctor if your symptoms do not improve. Do not stop using any medications without a doctor's advice.
SevelamerErgocalciferol
Severe
How does the drug interact with Vapcar 400mg Tablet DT:
Co-administration of Vapcar 400mg Tablet DT with Ergocalciferol can decrease the effects of Ergocalciferol.

How to manage the interaction:
Co-administration of Vapcar 400mg Tablet DT with Ergocalciferol can lead to an interaction, but they can be taken if advised by your doctor. Consult the doctor if your symptoms worsen. Do not stop using any drugs without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Include fresh fruits, vegetables, rice, milk, unenriched corn, and rice cereals.
  • Avoid or limit high-phosphorus foods that are high in additives (processed meats, instant puddings, sauces, spreadable cheeses, and beverage products).
  • Make sure you drink plenty of fluids. This will help you clear out the extra phosphate.

Habit Forming

No

Therapeutic Class

HYPOPHOSPHATEMIC AGENT

Vapcar 400mg Tablet DT Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Consult your doctor

It is not known if alcohol interacts with Vapcar 400mg Tablet DT. Please consult a doctor.

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Pregnancy

Caution

Sevelamer is a Category C pregnancy medicine. Please consult your doctor if you have any concerns; your doctor will prescribe you Vapcar 400mg Tablet DT only if the benefits outweigh the risks.

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Breast Feeding

Caution

It is unknown if Sevelamer passes into breastmilk or affects the baby. Please consult your doctor before using Vapcar 400mg Tablet DT if you are a breastfeeding mother.

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Driving

Safe if prescribed

Vapcar 400mg Tablet DT has no or negligible influence on the ability to drive or operate any machinery.

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Liver

Caution

Vapcar 400mg Tablet DT should be used with caution in patients with liver impairment/liver disease. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Safe if prescribed

Vapcar 400mg Tablet DT may be safe for patients with kidney problems. However, please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Caution

Vapcar 400mg Tablet DT is not recommended for children below 6 years as its safety and effectiveness are not known.

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Heart

Inform your doctor if you have heart disease before using Vapcar 400mg Tablet DT. Your doctor will prescribe only if the benefits outweigh the risks.

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Geriatrics

Caution

Vapcar 400mg Tablet DT may require dose adjustment in elderly patients based on their condition and medical requirements.

Have a query?

FAQs

Vapcar 400mg Tablet DT is used to control high phosphate levels in the body (hyperphosphataemia)‚ in adult patients on dialysis (a blood clearance technique), patients undergoing hemodialysis (using a blood filtration machine), and patients with chronic kidney disease. It is also used for the treatment of bone disease.

Vapcar 400mg Tablet DT contains sevelamer, which binds to phosphate in the gut and reduces its absorption. This helps lower high phosphate levels in the blood and prevents their harmful build-up in the body.

Yes, constipation is a common side effect of Vapcar 400mg Tablet DT. Consult your doctor if you have constipation, as it could be an early symptom of intestinal blockage.

Yes, serum phosphate levels should be monitored regularly while you are taking Vapcar 400mg Tablet DT. The use of Vapcar 400mg Tablet DT may decrease the levels of vitamin D, A, E, K, and folic acid, and hence, the levels need to be monitored during the treatment.

No, do not stop taking Vapcar 400mg Tablet DT on your own. Taking Vapcar 400mg Tablet DT is important to maintain phosphate levels and prevent calcification in the blood vessels. Consult your doctor if you consider stopping Vapcar 400mg Tablet DT treatment.

The side effects of Vapcar 400mg Tablet DT include diarrhoea, headache, stomach upset, and constipation. If these side effects persist or worsen, please consult your doctor.

Take Vapcar 400mg Tablet DT for as long as it is prescribed by your doctor. The dose and duration will depend on the response to treatment. Follow your doctor's instructions and do not stop taking Vapcar 400mg Tablet DT on your own.

Yes, Vapcar 400mg Tablet DT can be taken with food as it works by binding to phosphate from food.

Vapcar 400mg Tablet DT should be avoided by patients who are allergic to it and who have low phosphate levels in blood. Additionally, patients having intestinal obstruction should also avoid taking Vapcar 400mg Tablet DT.

You are recommended to consult your doctor before taking other medicines with Vapcar 400mg Tablet DT to avoid drug interactions.

Country of origin

India
Other Info - VA32717

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Reference

  1. https://www.medicines.org.uk/emc/files/pil.13045.pdf
  2. https://www.campus.sanofi/dam/jcr:4ee8fb92-5a0a-4910-b694-ec109ad0a0ac/Renvela%20Sachets%20API%20KSApdf.pdf
  3. https://products.sanofi.us/renvela/renvela.pdf
  4. https://www.accessdata.fda.gov/drugsatfda_docs/label/2014/022127s011lbl.pdf
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