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compositionComposition:SODIUM VALPROATE-200MG
prescriptionPrescription Medicine
Valrate Syrup 100 ml

Valrate Syrup is used to treat epilepsy/seizures/fits. Additionally, it is also used to treat bipolar disorder and prevent symptoms of migraine (like a headache). It helps reduce mood swings and improve impulsive behaviour.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

SODIUM VALPROATE-200MG

Manufacturer/Marketer :

3C Pharmaceuticals Pvt Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

NPPA :

Regulated

About Valrate Syrup

Valrate Syrup is used to treat epilepsy/seizures/fits. Additionally, Valrate Syrup is also used to treat bipolar disorder and prevent symptoms of migraine (like a headache). Epilepsy is a sudden rush of electricity in the brain.

Valrate Syrup contains 'Sodium valproate', which decreases the excessive and abnormal nerve activity in the brain. This helps in controlling seizures.

Take Valrate Syrup as prescribed by your doctor. Valrate Syrup may cause side effects, such as stomach pain, nausea, vomiting, dry mouth, tremors, tiredness, sleepiness, headache, weight gain, and hair loss. Talk to your doctor if you experience these side effects persistently.

Please do not stop taking Valrate Syrup without consulting your doctor to avoid worsening of seizures. Do not take Valrate Syrup if you are pregnant, as it could cause serious congenital disabilities. Consult your doctor before taking Valrate Syrup if you are breastfeeding.

Uses of Valrate Syrup

Valrate Syrup is used in the treatment of epilepsy, bipolar disorder, and migraine. The detailed uses of Valrate Syrup are as follows:

  • Seizure Management: Valrate Syrup is primarily used to manage various types of seizures in individuals with epilepsy, helping to stabilise electrical activity in the brain.
  • Bipolar Disorder Treatment: Valrate Syrup can be used in the treatment of bipolar disorder, aiding in mood stabilisation and reducing the frequency of mood swings.
  • Migraine: Valrate Syrup is used to help prevent migraine headaches. It reduces the frequency and severity of migraine attacks by stabilising nerve activity in the brain.

Have a query?

Directions for Use

  • Valrate Syrup can be taken with or without food.
  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Swallow Valrate Syrup as a whole with a glass of water.
  • Do not crush, break, or chew it.

Key Benefits

When used as prescribed, Valrate Syrup may offer the following benefits

For Epilepsy:

  • Regulates a variety of seizure types, such as absence, focal, and generalised seizures.
  • Reduces the frequency and intensity of seizures by stabilising aberrant electrical activity in the brain.
  • Beneficial either alone or in conjunction with other antiepileptic medications.
  • Both adults and children with epilepsy can benefit from it.

For Bipolar disorder:

  • Stabilises mood, which aids in the management of acute manic episodes.
  • Reduce mood fluctuations and stop manic relapses.
  • Helpful for patients who don't react well to lithium.
  • Reduces impulsive behaviour, agitation, and irritation.

For Migraine:

  • Helps prevent migraine attacks when taken regularly.
  • Reduces the frequency of migraine episodes.
  • Decreases the severity and duration of headaches.
  • Stabilises overactive nerve signals involved in migraines.
  • Improves the quality of life in people with recurrent migraines.

How Valrate Syrup Works

Valrate Syrup contains 'Sodium valproate' as an active ingredient. • For seizures, it decreases the excessive and abnormal nerve activity in the brain. Thereby, it helps in controlling seizures. • For Bipolar disorder, it increases the amount of a chemical substance called GABA; this helps block the nerve transmission across the brain and provides a calming effect. Thereby helps treat bipolar disorder. • For Migraine, it controls abnormal nerve signals and prevents the chain of events that trigger migraine attacks, helping reduce the frequency and severity of migraines.

Storage

Store in a cool and dry place away from sunlight

What if I have taken an overdose of Valrate Syrup

An overdose of Valrate Syrup may cause headache, dizziness, confusion, memory loss, tiredness, feeling sick or being sick, blurred vision due to pupil of the eye becoming smaller, poor reflexes, weak or floppy muscles, fits, loss of consciousness, behavioural changes and breathing difficulties such as fast breathing, shortness of breath or chest pain. If you suspect you have taken an overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

  • Do not take Valrate Syrup if you are allergic to any of its contents.
  • Inform your doctor if you have liver problems, porphyria (blood disorder), urine-related problems (like urea cycle disorder), diabetes, an immune system disorder or kidney problems.
  • Consult your doctor immediately if you experience suicidal tendencies while taking Valrate Syrup .
  • Contact your doctor if your child gets her first period during the treatment with Valrate Syrup .
  • Do not take Valrate Syrup if you are pregnant unless prescribed by the doctor, as it can cause serious congenital disabilities.
  • Consult your doctor before taking Valrate Syrup if you are breastfeeding.
  • Valrate Syrup may cause drowsiness and dizziness, so drive only if you are alert.
  • Avoid consuming alcohol along with Valrate Syrup as it could lead to increased dizziness and sleepiness.

Drug-Drug Interactions

verifiedApollotooltip
Sodium ValproateSodium phenylbutyrate
Critical
Sodium ValproateDoripenem
Severe

Drug-Drug Interactions

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Sodium ValproateSodium phenylbutyrate
Critical
How does the drug interact with Valrate Syrup 100 ml:
Combining Sodium phenylbutyrate and Valrate Syrup 100 ml can increase ammonia levels in the blood.

How to manage the interaction:
Taking Sodium phenylbutyrate with Valrate Syrup 100 ml is not recommended, but it can be taken if prescribed by a doctor. If you experience any symptoms like sudden dizziness, lightheadedness, fainting, headache, shortness of breath, nausea, vomiting, chest pain or tightness, rapid heartbeat, or memory loss, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
Sodium ValproateDoripenem
Severe
How does the drug interact with Valrate Syrup 100 ml:
Co-administration of Valrate Syrup 100 ml with doripenem can reduce the blood levels of valproic acid.

How to manage the interaction:
Co-administration of Doripenam and Valrate Syrup 100 ml can lead to an interaction, it can be taken if advised by your doctor. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, involuntary muscle movements, or memory loss, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
Sodium ValproateMeropenem
Severe
How does the drug interact with Valrate Syrup 100 ml:
Co-administration of Meropenam and Valrate Syrup 100 ml together can reduce the effect of Valrate Syrup 100 ml.

How to manage the interaction:
Co-administration of Meropenam and Valrate Syrup 100 ml can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any unusual symptoms, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
Sodium ValproateLeflunomide
Severe
How does the drug interact with Valrate Syrup 100 ml:
Co-administration of Leflunomide and Valrate Syrup 100 ml can increase the risk of causing liver problems.

How to manage the interaction:
Co-administration of Leflunomide and Valrate Syrup 100 ml can lead to an interaction, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Sodium ValproateKetamine
Severe
How does the drug interact with Valrate Syrup 100 ml:
Co-administration of Ketamine and Valrate Syrup 100 ml can increase side effects and cause respiratory depression.

How to manage the interaction:
Co-administration of Ketamine and Valrate Syrup 100 ml can lead to an interaction, but it can be taken if your doctor advises. However, consult your doctor immediately if you experience any symptoms like dizziness, drowsiness, confusion, difficulty concentrating, excessive sedation, impaired thinking, judgment, and motor coordination. Avoid driving or operating hazardous machinery until you know how these medications affect you. Do not discontinue any medications without consulting the doctor.
Sodium ValproateTeriflunomide
Severe
How does the drug interact with Valrate Syrup 100 ml:
Co-administration of Teriflunomide and Valrate Syrup 100 ml can increase the risk of causing liver problems.

How to manage the interaction:
Co-administration of Teriflunomide and Valrate Syrup 100 ml can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark-colored urine, light-colored stools, and yellowing of the skin or eyes. Avoid alcohol while taking these medications, and consult your doctor immediately. Do not discontinue any medications without consulting your doctor.
Sodium ValproateVorinostat
Severe
How does the drug interact with Valrate Syrup 100 ml:
Co-administration of Vorinostat with Valrate Syrup 100 ml can increase the risk of unusual bleeding.

How to manage the interaction:
Co-administration of Vorinostat and Valrate Syrup 100 ml can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult your doctor immediately. Do not discontinue any medications without consulting your doctor.
Sodium ValproateBuprenorphine
Severe
How does the drug interact with Valrate Syrup 100 ml:
Using buprenorphine together with Valrate Syrup 100 ml may increase the risk of severe side effects, including respiratory problems and loss of consciousness.

How to manage the interaction:
Although the administration of buprenorphine alongside Valrate Syrup 100 ml can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Sodium ValproateLithium
Severe
How does the drug interact with Valrate Syrup 100 ml:
Co-administration of Lithium with Valrate Syrup 100 ml can increase the risk irregular heart rhythm.

How to manage the interaction:
Co-administration of Lithium and Valrate Syrup 100 ml can lead to an interaction, but it can be taken if advised by your doctor. However, consult your doctor immediately if you experience any symptoms like dizziness, drowsiness, confusion, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, and difficulty concentrating. Do not discontinue any medications without consulting a doctor.
Sodium ValproateErtapenem
Severe
How does the drug interact with Valrate Syrup 100 ml:
The combined use of Ertapenem and Valrate Syrup 100 ml can reduce the blood levels of valproic acid.

How to manage the interaction:
Co-administration of Ertapenem and Valrate Syrup 100 ml can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like loss of seizure control or changes in behavior, consult your doctor immediately. Do not discontinue any medications without consulting the doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

Healthy eating habits:

  • To preserve general health, eat a diet rich in fruits, vegetables, whole grains, and lean meats.
  • Eat fewer greasy and fried foods to ease the liver's burden.
  • To lessen upset stomach, drink enough water and eat at regular times.

Lifestyle changes:

  • Steer clear of recreational drugs and alcohol, as they can exacerbate seizures and negative effects.
  • Sleep deprivation can cause mood swings or seizures, so make sure you get enough sleep and control your stress.

Stress management:

  • To lower stress, engage in relaxation methods like yoga, meditation, or deep breathing.
  • Walking is a gentle kind of exercise that might enhance mental health.
  • When you're feeling overwhelmed, ask friends, family, or a counsellor for emotional assistance.

Habit Forming

No

Therapeutic Class

[ANTICONVULSANT]

All Substitutes & Brand Comparisons

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Alcohol

Unsafe

Avoid consumption of alcohol while taking Valrate Syrup as it may cause increased dizziness and sleepiness.

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Pregnancy

Unsafe

Valrate Syrup belongs to pregnancy category D. Avoid taking Valrate Syrup if you are pregnant as it could lead to serious birth defects.

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Breast Feeding

Consult your doctor

Valrate Syrup may pass into breastmilk. Consult your doctor before taking Valrate Syrup if you are breastfeeding.

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Driving

Unsafe

Valrate Syrup causes dizziness, sleepiness and tiredness. Do not drive or operate machinery unless you are alert.

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Liver

Unsafe

Valrate Syrup should not be used if you have liver problems or your family has a history of liver problems. Please consult your doctor if you have any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Consult your doctor

Valrate Syrup can be given to children if prescribed by the doctor. The dose will be adjusted by the doctor depending upon the child's body weight.

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Heart

Consult your doctor

It is unknown whether Valrate Syrup is safe for use in cardiac patients or not. Please consult your physician.

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Geriatrics

Caution

Valrate Syrup should be given with caution in elderly patients due to age-related side effects. Seek medical advice before using Valrate Syrup .

FAQs

Valrate Syrup is used to treat epilepsy/seizures/fits. Additionally, it is also used to treat bipolar disorder and prevent symptoms of migraine (like a headache).

Valrate Syrup decreases the excessive and abnormal nerve activity in the brain. It balances the brain's chemical messenger and prevents overactivity of the brain, thereby controlling seizure episodes.

Valrate Syrup helps to treat manic episodes associated with bipolar disorder by increasing the amount of a chemical substance called GABA; this helps in blocking the nerve transmission across the brain and provides a calming effect.

Valrate Syrup limits the transmission of nerve pain, thereby preventing migraine headaches. Migraines are a neurological condition characterised by intense headaches.

Do not discontinue Valrate Syrup without consulting your doctor. To treat your condition effectively, continue taking Valrate Syrup for as long as prescribed. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Valrate Syrup ; your doctor will reduce the dose gradually to avoid worsening of seizures.

Birth-control pills like oestrogen-containing products may affect the way Valrate Syrup works. It is better to consult the doctor if you are using birth control pills to avoid pregnancy.

Valrate Syrup may cause weight gain due to an increase in appetite. Maintain a healthy weight by following a proper diet and exercising regularly.

Valrate Syrup might cause fertility issues in both men and women. However, it can be reversible upon discontinuation of Valrate Syrup . In rare cases, Valrate Syrup can be a contributing factor in male infertility.

Limit caffeine intake, avoid smoking and mouthwashes containing alcohol, drink water regularly, and chew sugar-free gum/candy might prevent dry mouth.

Valrate Syrup may change the results of liver enzymes, urine and blood tests. Inform the person doing the tests that you are taking Valrate Syrup .

Store Valrate Syrup at room temperature, in a dry place. Keep out of sight and reach of children.

Valrate Syrup may cause side effects like stomach pain, nausea, vomiting, dry mouth, tremors, tiredness, sleepiness, headache, weight gain, and hair loss. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

No, avoid consumption of alcohol while taking Valrate Syrup as it may cause increased dizziness and sleepiness.

Yes, Valrate Syrup causes dizziness, sleepiness and tiredness. Do not drive or operate machinery unless you are alert.

No, taking higher than the recommended dose of Valrate Syrup will not be more effective and may cause unpleasant side effects. Do not take more than the prescribed dose of Valrate Syrup as it may cause an overdose.

Country of origin

India

Manufacturer/Marketer address

142 AB, Kandivli Industrial Estate, Kandivli (West), Mumbai - 400 067, Maharashtra.
Other Info - VAL0117

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