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  3. Valpofin-500 CR Tablet 10's

Valpofin-500 CR Tablet 10's, Pack of 10
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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Valpofin-500 CR Tablet 10's is used to treat epilepsy/seizures/fits. Additionally, it is also used to treat bipolar disorder and prevent symptoms of migraine (like a headache). It contains Sodium valproate, which decreases the excessive and abnormal nerve activity in the brain. Thereby, helps in controlling seizures. It helps block the nerve transmission across the brain and provides a calming effect. In some cases, you may experience certain common side effects, such as stomach pain, nausea, vomiting, dry mouth, tremors, tiredness, sleepiness, headache, weight gain, and hair loss. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Composition :

SODIUM VALPROATE-500MG

Manufacturer/Marketer :

Intra Life Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Valpofin-500 CR Tablet 10's

Valpofin-500 CR Tablet 10's is used to treat epilepsy/seizures/fits. Additionally, Valpofin-500 CR Tablet 10's is also used to treat bipolar disorder and prevent symptoms of migraine (like a headache). Epilepsy is a sudden rush of electricity in the brain. In epilepsy, the brain's electrical rhythms become imbalanced, resulting in recurrent seizures, sometimes leading to an unconscious state. 
­ 
Valpofin-500 CR Tablet 10's contains 'Sodium valproate', which decreases the excessive and abnormal nerve activity in the brain. Thereby helps in controlling seizures. Valpofin-500 CR Tablet 10's increases the amount of a chemical substance called GABA; this helps block the nerve transmission across the brain and provides a calming effect. Thereby helps treat bipolar disorder. 
 
You can take Valpofin-500 CR Tablet 10's with or without food. You are advised to take Valpofin-500 CR Tablet 10's as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side effects, such as stomach pain, nausea, vomiting, dry mouth, tremors, tiredness, sleepiness, headache, weight gain, and hair loss. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
 
Please do not stop taking Valpofin-500 CR Tablet 10's without consulting your doctor to avoid worsening of seizures. Contact your doctor if your child gets her first period whilst on treatment with Valpofin-500 CR Tablet 10's. Do not take Valpofin-500 CR Tablet 10's if you are pregnant, as it could cause serious congenital disabilities. If you are of childbearing age, use effective contraception while taking Valpofin-500 CR Tablet 10's. Consult your doctor before taking Valpofin-500 CR Tablet 10's if you are breastfeeding. Do not drive or operate machinery as Valpofin-500 CR Tablet 10's may cause drowsiness and dizziness. Avoid consuming alcohol along with Valpofin-500 CR Tablet 10's as it could lead to increased dizziness and sleepiness.

Uses of Valpofin-500 CR Tablet 10's

Valpofin-500 CR Tablet 10's is used in the treatment of epilepsy, bipolar disorder, and migraine. The detailed uses of Valpofin-500 CR Tablet 10's are as follows:<br/>• Seizure Management: Valpofin-500 CR Tablet 10's is primarily used to manage various types of seizures in individuals with epilepsy, helping to stabilise electrical activity in the brain.<br/>• Bipolar Disorder Treatment: Valpofin-500 CR Tablet 10's can be utilized in the treatment of bipolar disorder, aiding in mood stabilization and reducing the frequency of mood swings.<br/>• Migraine Prevention: Valpofin-500 CR Tablet 10's may also be prescribed to prevent migraines, providing relief from recurrent headaches.<br/>

Directions for Use

  • Valpofin-500 CR Tablet 10's can be taken with or without food.
  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Swallow Valpofin-500 CR Tablet 10's as a whole with a glass of water.
  • Do not crush, break, or chew it.

Medicinal Benefits

Valpofin-500 CR Tablet 10's belongs to a group of anticonvulsants or anti-epileptics used to treat epilepsy (fits). Additionally, Valpofin-500 CR Tablet 10's is also used to treat bipolar disorder and prevent migraine headaches. Valpofin-500 CR Tablet 10's decreases the excessive and abnormal nerve activity in the brain, thereby controlling seizures. Valpofin-500 CR Tablet 10's is used to treat both localized (seizures which affect only a part of the brain) and generalized seizures (seizures which affect the entire brain).

How Valpofin-500 CR Tablet 10's Works

Valpofin-500 CR Tablet 10's contains 'Sodium valproate', which decreases the excessive and abnormal nerve activity in the brain. Thereby helps in controlling seizures. Valpofin-500 CR Tablet 10's increases the amount of a chemical substance called GABA; this helps block the nerve transmission across the brain and provides a calming effect. Thereby helps treat bipolar disorder.

Storage

Keep Valpofin-500 CR Tablet 10's out of reach and sight of children.
Side effects of Valpofin-500 CR Tablet
  • Reduce salt intake to minimize fluid buildup.
  • Use compression stockings, sleeves, or gloves.
  • Gently massage the affected area towards the heart.
  • Protect the swollen area from injury and keep it clean.
  • Use lotion or cream to keep the skin moisturized.
  • Do not stand up suddenly. Lie down and get up slowly only when you feel better.
  • Avoid alcohol and large meals.
  • Drink enough water before standing for long periods.
  • Exercise regularly; however, avoid exercising in extreme heat.
  • Eat small, low-carb meals.
  • Wear compression stockings.
Here are the steps to manage the medication-triggered Tachycardia (Fast Heart Rate):
  • Contact your doctor immediately if you're experiencing a fast heart rate, palpitations, or other heart-related symptoms. This is crucial to determine whether the symptoms are related to your medication.
  • Your doctor may need to adjust your medication regimen to alleviate the fast heart rate symptoms. This could involve changing the medication, reducing the dosage, or adding new medications to counteract the side effects.
  • Follow your doctor's advice on monitoring your heart rate and blood pressure. This will help track any changes and ensure your heart rate returns normal.
  • If you experience severe symptoms such as chest pain, dizziness, or shortness of breath, seek immediate medical attention. These symptoms can indicate a more serious condition that requires prompt treatment.
  • Regular exercise increases nitric oxide, relaxing blood vessels and improving circulation.
  • Avoid smoking and alcohol consumption as they can damage blood vessels and worsen vasodilation.
  • Foods high in omega-3 fatty acids such as walnuts, flaxseeds and fatty fish improve cardiovascular health and lower inflammation.
  • Limit the amount of salt in your regular diet.
  • Avoid triggers like alcohol, caffeine, and energy drinks.
  • Try relaxation techniques such as yoga, meditation, or deep breathing.
  • Exercise regularly as it helps maintain heart health.
  • Follow a nutritious and balanced diet.
  • Hallucination is a major psychotic disorder that needs immediate medical attention.
  • Acknowledge your experience and put effort to control hallucinations. You can share what is being seen with a therapist to know whether they are real or imaginary.
  • Avoid smoking and alcohol intake as it can worsen the condition and increase your imagination.
  • Practice meditation and yoga to avoid anxiety, which can be one of the leading causes of hallucinations.
  • Talk to your dietician and consume food that can improve your mental health.

What if I have taken an overdose of Valpofin-500 CR Tablet 10's

Do not take more than the prescribed dose of Valpofin-500 CR Tablet 10's as it may cause an overdose. The symptoms of overdose include headache, dizziness, confusion, memory loss, tiredness, feeling sick or being sick, blurred vision due to pupil of the eye becoming smaller, poor reflexes, weak or floppy muscles, fits, loss of consciousness, behavioural changes and breathing difficulties such as fast breathing, shortness of breath or chest pain. If you suspect you have taken an overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Do not take Valpofin-500 CR Tablet 10's if you are allergic to any of its contents; if you have liver problems, porphyria, urine-related problems (like urea cycle disorder), diabetes, an immune system disorder or kidney problems. Consult your doctor immediately if you experience suicidal tendencies while taking Valpofin-500 CR Tablet 10's. Contact your doctor if your child gets her first period during the treatment with Valpofin-500 CR Tablet 10's. Do not take Valpofin-500 CR Tablet 10's if you are pregnant unless prescribed by the doctor, as it is a pregnancy category C medicine and can cause serious congenital disabilities. Consult your doctor before taking Valpofin-500 CR Tablet 10's if you are breastfeeding. Valpofin-500 CR Tablet 10's may cause drowsiness and dizziness, so drive only if you are alert. Avoid consuming alcohol along with Valpofin-500 CR Tablet 10's as it could lead to increased dizziness and sleepiness. 

Drug-Drug Interactions

verifiedApollotooltip
Sodium ValproateSodium phenylbutyrate
Critical
Sodium ValproateDoripenem
Severe

Drug-Drug Interactions

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Sodium ValproateSodium phenylbutyrate
Critical
How does the drug interact with Valpofin-500 CR Tablet:
Combining Sodium phenylbutyrate and Valpofin-500 CR Tablet can increase ammonia levels in the blood.

How to manage the interaction:
Taking Sodium phenylbutyrate with Valpofin-500 CR Tablet is not recommended, but it can be taken if prescribed by a doctor. If you experience any symptoms like sudden dizziness, lightheadedness, fainting, headache, shortness of breath, nausea, vomiting, chest pain or tightness, rapid heartbeat, or memory loss, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
Sodium ValproateDoripenem
Severe
How does the drug interact with Valpofin-500 CR Tablet:
Co-administration of Valpofin-500 CR Tablet with doripenem can reduce the blood levels of valproic acid.

How to manage the interaction:
Co-administration of Doripenam and Valpofin-500 CR Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, involuntary muscle movements, or memory loss, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
Sodium ValproateLithium
Severe
How does the drug interact with Valpofin-500 CR Tablet:
Co-administration of Lithium with Valpofin-500 CR Tablet can increase the risk irregular heart rhythm.

How to manage the interaction:
Co-administration of Lithium and Valpofin-500 CR Tablet can lead to an interaction, but it can be taken if advised by your doctor. However, consult your doctor immediately if you experience any symptoms like dizziness, drowsiness, confusion, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, and difficulty concentrating. Do not discontinue any medications without consulting a doctor.
Sodium ValproateKetamine
Severe
How does the drug interact with Valpofin-500 CR Tablet:
Co-administration of Ketamine and Valpofin-500 CR Tablet can increase side effects and cause respiratory depression.

How to manage the interaction:
Co-administration of Ketamine and Valpofin-500 CR Tablet can lead to an interaction, but it can be taken if your doctor advises. However, consult your doctor immediately if you experience any symptoms like dizziness, drowsiness, confusion, difficulty concentrating, excessive sedation, impaired thinking, judgment, and motor coordination. Avoid driving or operating hazardous machinery until you know how these medications affect you. Do not discontinue any medications without consulting the doctor.
Sodium ValproateTeriflunomide
Severe
How does the drug interact with Valpofin-500 CR Tablet:
Co-administration of Teriflunomide and Valpofin-500 CR Tablet can increase the risk of causing liver problems.

How to manage the interaction:
Co-administration of Teriflunomide and Valpofin-500 CR Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark-colored urine, light-colored stools, and yellowing of the skin or eyes. Avoid alcohol while taking these medications, and consult your doctor immediately. Do not discontinue any medications without consulting your doctor.
Sodium ValproateVorinostat
Severe
How does the drug interact with Valpofin-500 CR Tablet:
Co-administration of Vorinostat with Valpofin-500 CR Tablet can increase the risk of unusual bleeding.

How to manage the interaction:
Co-administration of Vorinostat and Valpofin-500 CR Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult your doctor immediately. Do not discontinue any medications without consulting your doctor.
Sodium ValproateBuprenorphine
Severe
How does the drug interact with Valpofin-500 CR Tablet:
Using buprenorphine together with Valpofin-500 CR Tablet may increase the risk of severe side effects, including respiratory problems and loss of consciousness.

How to manage the interaction:
Although the administration of buprenorphine alongside Valpofin-500 CR Tablet can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Sodium ValproateMeropenem
Severe
How does the drug interact with Valpofin-500 CR Tablet:
Co-administration of Meropenam and Valpofin-500 CR Tablet together can reduce the effect of Valpofin-500 CR Tablet.

How to manage the interaction:
Co-administration of Meropenam and Valpofin-500 CR Tablet can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any unusual symptoms, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
Sodium ValproateErtapenem
Severe
How does the drug interact with Valpofin-500 CR Tablet:
The combined use of Ertapenem and Valpofin-500 CR Tablet can reduce the blood levels of valproic acid.

How to manage the interaction:
Co-administration of Ertapenem and Valpofin-500 CR Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like loss of seizure control or changes in behavior, consult your doctor immediately. Do not discontinue any medications without consulting the doctor.
Sodium ValproateLeflunomide
Severe
How does the drug interact with Valpofin-500 CR Tablet:
Co-administration of Leflunomide and Valpofin-500 CR Tablet can increase the risk of causing liver problems.

How to manage the interaction:
Co-administration of Leflunomide and Valpofin-500 CR Tablet can lead to an interaction, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • A ketogenic diet (low in carbohydrates and high in fats) is recommended for children with epilepsy. This diet helps in utilizing fat instead of glucose for the generation of energy.
  • Atkins diet (high fat and controlled carbohydrates) is recommended for adolescents and adults.
  • Exercising regularly helps maintain weight and improve overall health. 
  • Rest well; get plenty of sleep.
  • Avoid smoking and alcohol consumption.
  • Meditation and yoga can help lower stress, decrease pain sensitivity and improve coping skills.
  • Have a seizure response plan that helps those around you know what to do.
  • Prepare your living area; small changes may help reduce the risk of physical injury during a seizure.
  • Understand what triggers seizures and try reducing or avoiding them.
  • Please pay attention to overall health, as it can help reduce seizure activity.
  • Install an alarm or emergency device to get assistance during a seizure attack.

Habit Forming

No

Therapeutic Class

ANTICONVULSANT

Valpofin-500 CR Tablet 10's Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Unsafe

Avoid consumption of alcohol while taking Valpofin-500 CR Tablet 10's as it may cause increased dizziness and sleepiness.

bannner image

Pregnancy

Unsafe

Valpofin-500 CR Tablet 10's belongs to pregnancy category D. Avoid taking Valpofin-500 CR Tablet 10's if you are pregnant as it could lead to serious birth defects.

bannner image

Breast Feeding

Consult your doctor

Valpofin-500 CR Tablet 10's may pass into breastmilk. Consult your doctor before taking Valpofin-500 CR Tablet 10's if you are breastfeeding.

bannner image

Driving

Unsafe

Valpofin-500 CR Tablet 10's causes dizziness, sleepiness and tiredness. Do not drive or operate machinery unless you are alert.

bannner image

Liver

Unsafe

Valpofin-500 CR Tablet 10's should not be used if you have liver problems or your family has a history of liver problems. Please consult your doctor if you have any concerns regarding this.

bannner image

Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

bannner image

Children

Safe if prescribed

Valpofin-500 CR Tablet 10's can be given to children if prescribed by the doctor. The dose will be adjusted by the doctor depending upon the child's body weight.

Have a query?

FAQs

Valpofin-500 CR Tablet 10's is used to treat epilepsy/seizures/fits. Additionally, it is also used to treat bipolar disorder and prevent symptoms of migraine (like a headache).

Valpofin-500 CR Tablet 10's decreases the excessive and abnormal nerve activity in the brain. It balances the brain&amp;#039;s chemical messenger and prevents overactivity of the brain, thereby controlling seizures episodes.

Valpofin-500 CR Tablet 10's helps to treat manic episodes associated with bipolar disorder by increasing the amount of a chemical substance called GABA; this helps in blocking the nerve transmission across the brain and provides a calming effect.

Valpofin-500 CR Tablet 10's limits the transmission of nerve pain, thereby prevents migraine headache. Migraine is a neurological condition which is characterized by intense headaches.

Do not discontinue Valpofin-500 CR Tablet 10's without consulting your doctor. To treat your condition effectually, continue taking Valpofin-500 CR Tablet 10's for as long as prescribed. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Valpofin-500 CR Tablet 10's; your doctor will reduce the dose gradually to avoid worsening of seizures.

Birth-control pills like oestrogen-containing products may affect the way Valpofin-500 CR Tablet 10's works. It is better to consult the doctor if you are using birth control pills to avoid pregnancy.

Valpofin-500 CR Tablet 10's may cause weight gain due to an increase in appetite. Maintain a healthy weight by following a proper diet and exercising regularly.

Valpofin-500 CR Tablet 10's might cause fertility issues in both men and women. However, it can be reversible upon discontinuation of Valpofin-500 CR Tablet 10's. In rare cases, Valpofin-500 CR Tablet 10's can be a contributing factor in male infertility.

Limit caffeine intake, avoid smoking and mouthwashes containing alcohol, drink water regularly, and chew sugar-free gum/candy might prevent dry mouth.

Valpofin-500 CR Tablet 10's may change the results of liver enzymes, and urine and blood tests. Inform the person doing the tests that you are taking Valpofin-500 CR Tablet 10's.

Store Valpofin-500 CR Tablet 10's at room temperature, in a dry place. Keep out of sight and reach of children.

Valpofin-500 CR Tablet 10's may cause side effects like stomach pain, nausea, vomiting, dry mouth, tremors, tiredness, sleepiness, headache, weight gain, and hair loss. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

No, avoid consumption of alcohol while taking Valpofin-500 CR Tablet 10's as it may cause increased dizziness and sleepiness.

Yes, Valpofin-500 CR Tablet 10's causes dizziness, sleepiness and tiredness. Do not drive or operate machinery unless you are alert.

No, taking higher than the recommended dose of Valpofin-500 CR Tablet 10's will not be more effective and may cause unpleasant side effects. Do not take more than the prescribed dose of Valpofin-500 CR Tablet 10's as it may cause an overdose.

Country of origin

India

Manufacturer/Marketer address

61/C, 6TH MAIN ROAD, 4TH PHASE, 7TH BLOCK, B.S.K, 3RD STAGE, BANGALORE-560085
Other Info - VAL0600

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Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 18, 2025 | 6:42 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.medicines.org.uk/emc/files/pil.1500.pdf
  2. https://www.nhs.uk/medicines/sodium-valproate/http://mri.cts-mrp.eu/download/DE_H_0642_002_FinalPI_2of4.pdf
  3. https://www.drugs.com/cons/valproate-sodium-intravenous.html
  4. https://www.medsafe.govt.nz/consumers/cmi/e/Epilim.pdf

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