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  3. Urotek 500000 IU Injection 1's

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Urotek 500000 IU Injection 1's, Pack of 1
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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
Urotek 500000 IU Injection 1's belongs to a class of drugs called antithrombotic agents. It is used in the treatment of blood clots mainly in conditions like peripheral vascular thromboembolism (blood clot in a large vein), cerebral thrombosis, cerebral infarction (stroke), and myocardial infarction (heart attack). This medicine works by converting plasminogen to the plasmin enzyme, which dissolves the blood clots, thus restoring the blood flow to the affected area.
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Composition :

UROKINASE-500000IU

Manufacturer/Marketer :

Protech Telelinks

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Urotek 500000 IU Injection 1's

Urotek 500000 IU Injection 1's belongs to a class of drugs called antithrombotic agents used to dissolve harmful blood clots in blood vessels. It is used in conditions such as peripheral vascular thromboembolism (blood clot in a large vein), cerebral thrombosis (blood clot in venous sinuses of the brain), cerebral infarction (stroke), myocardial infarction (heart attack),  and pulmonary embolism (blood clots in the lungs).

Urotek 500000 IU Injection 1's contains urokinase that works by converting plasminogen to the enzyme plasmin. Plasmin degrades fibrin clots as well as fibrinogen and some other plasma proteins. It effectively dissolves the blood clots, restoring the blood flow to the affected area.

Urotek 500000 IU Injection 1's will be administered by a healthcare professional. In some cases, Urotek 500000 IU Injection 1's may cause unusual bleeding, nausea, vomiting, and loss of appetite. Most of these side effects do not necessitate medical treatment and fade away with time. Please visit your doctor if the side effects persist or worsen.

If you are pregnant or breastfeeding, inform your doctor before taking Urotek 500000 IU Injection 1's. Keep your doctor updated on your medical condition and medications to rule out any potential interactions. Avoid consuming alcohol along with Urotek 500000 IU Injection 1's as it could increase the risk of bleeding. Urotek 500000 IU Injection 1's should not be given to children because its safety and effectiveness have not been proven.

Uses of Urotek 500000 IU Injection 1's

Urotek 500000 IU Injection 1's is used in the treatment of blood clots (thrombus). The detailed uses of Urotek 500000 IU Injection 1's are as follows:

  • Treats Blood Clots (Thrombus): Urotek 500000 IU Injection 1's helps dissolve harmful blood clots within blood vessels, thereby restoring normal blood flow.
  • Treats Peripheral Vascular Thromboembolism: Urotek 500000 IU Injection 1's is used to treat blood clots in large veins in the limbs, thus preventing complications like deep vein thrombosis.
  • Manages Cerebral Thrombosis: Urotek 500000 IU Injection 1's is used to treat blood clots in the venous sinuses of the brain, helping to reduce pressure and prevent further neurological damage.
  • Treats Cerebral Infraction (Ischemic Stroke): Urotek 500000 IU Injection 1's helps restore blood flow to the brain by dissolving blood clots that cause stroke.
  • Treats Pulmonary Embolism: Urotek 500000 IU Injection 1's is used to dissolve blood clots in the lungs, restoring blood supply, enhancing oxygen exchange, and preventing lung tissue damage.
  • Used in Myocardial Infarction (Heart Attack) : Urotek 500000 IU Injection 1's may be used in certain cases of heart attack to dissolve the clots causing blockage in the coronary arteries.

Have a query?

Directions for Use

  • Follow your doctor’s instructions on the dosage and timing of this medication.
  • Urotek 500000 IU Injection 1's should be administered by a nurse or doctor.
  • Do not self-administer.

Medicinal Benefits

Urotek 500000 IU Injection 1's belongs to a class of drugs known as antithrombotic medications. Urotek 500000 IU Injection 1's contains urokinase. It works by dissolving or lysing the harmful or unwanted blood clots in the blood vessels. Thus it restores the blood flow to the affected blood vessels, preventing various illnesses caused by blood clots. It is used in conditions such as peripheral vascular thromboembolism (blood clot in a large vein), cerebral thrombosis (blood clot in venous sinuses of the brain), cerebral infarction (stroke), myocardial infarction (heart attack),  and pulmonary embolism (blood clots in the lungs).

How Urotek 500000 IU Injection 1's Works

Urotek 500000 IU Injection 1's contains urokinase that works by converting plasminogen to the enzyme plasmin. Plasmin degrades fibrin clots as well as fibrinogen and some other plasma proteins. It effectively dissolves the blood clots, restoring the blood flow to the affected area.

Storage

• Store in a cool and dry place away from sunlight.• Keep out of sight and reach of children.• Cold chain - To be stored in cold places at 2ºC to 8ºC
Side effects of Urotek 500000 IU Injection

What if I have taken an overdose of Urotek 500000 IU Injection 1's

Since Urotek 500000 IU Injection 1's is administered by a healthcare professional, an overdose is unlikely to occur. However, seek medical attention if you experience any unusual symptoms.

Drug Warnings

Before taking Urotek 500000 IU Injection 1's, tell your doctor if you are pregnant or breastfeeding. Urotek 500000 IU Injection 1's should be used with caution in elderly people because they are at significant risk of bleeding. If you have active tuberculosis, stomach ulcers, severe uncontrolled arterial hypertension, bleeding abnormalities, severe hepatic or renal diseases, inform your doctor before taking Urotek 500000 IU Injection 1's. Also, let your doctor know if you have had a recent cerebrovascular accident, as well as intracranial or intraspinal surgery. Inform your doctor that you take Urotek 500000 IU Injection 1's if are due to undergo surgery. You should avoid alcohol because it increases the risk of bleeding. Urotek 500000 IU Injection 1's is not recommended for children since its safety and effectiveness have not been proven.

Drug-Drug Interactions

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UrokinaseDasatinib
Severe
UrokinaseDalteparin
Severe

Drug-Drug Interactions

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UrokinaseDasatinib
Severe
How does the drug interact with Urotek 500000 IU Injection:
Combining Dasatinib with Urotek 500000 IU Injection can increase the risk and severity of bleeding and hemorrhage.

How to manage the interaction:
Co-administration of Urotek 500000 IU Injection with Dasatinib can result in an interaction, but it can be taken if a doctor has advised it. If you notice any of these signs, it's important to contact a doctor right away: bleeding, problems, bruising, feeling dizzy or lightheaded, stools that are red or black and sticky, intense headache, weakness, bleeding, or vomiting. Do not discontinue any medications without consulting a doctor.
UrokinaseDalteparin
Severe
How does the drug interact with Urotek 500000 IU Injection:
Combining Urotek 500000 IU Injection with Dalteparin can increase the risk of bleeding.

How to manage the interaction:
Although taking Dalteparin with Urotek 500000 IU Injection may possibly lead to an interaction, they can be taken if a doctor prescribes it. Consult a doctor if you have any symptoms including dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that resembles coffee grounds, severe headache, and weakness. Without consulting a doctor, never stop taking any medication.
UrokinaseHeparin
Severe
How does the drug interact with Urotek 500000 IU Injection:
Taking Heparin with Urotek 500000 IU Injection can increase the risk of bleeding.

How to manage the interaction:
Co-administration of Heparin with Urotek 500000 IU Injection can result in an interaction, but it can be taken if a doctor has advised it. However, if you have unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
UrokinasePrasugrel
Severe
How does the drug interact with Urotek 500000 IU Injection:
Co-administration of Prasugrel with Urotek 500000 IU Injection can increase the risk of bleeding leading to serious blood loss.

How to manage the interaction:
Although taking Prasugrel and Urotek 500000 IU Injection together can evidently cause an interaction, it can be taken if a doctor has suggested it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
UrokinaseDabigatran etexilate
Severe
How does the drug interact with Urotek 500000 IU Injection:
Taking Dabigatran etexilate with Urotek 500000 IU Injection can increase the risk of bleeding leading to serious blood loss.

How to manage the interaction:
Taking Dabigatran etexilate with Urotek 500000 IU Injection together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
UrokinaseIbrutinib
Severe
How does the drug interact with Urotek 500000 IU Injection:
Co-administration of Ibrutinib with Urotek 500000 IU Injection can increase the risk of bleeding leading to serious blood loss.

How to manage the interaction:
Taking Ibrutinib with Urotek 500000 IU Injection together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor. Do not stop using any medications without a doctor's advice.
UrokinaseWarfarin
Severe
How does the drug interact with Urotek 500000 IU Injection:
Coadministration of warfarin with Urotek 500000 IU Injection can increase the risk of bleeding.

How to manage the interaction:
Although taking Urotek 500000 IU Injection and warfarin together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor. Do not stop using any medications without a doctor's advice.
UrokinaseApixaban
Severe
How does the drug interact with Urotek 500000 IU Injection:
Coadministration of Urotek 500000 IU Injection and Apixaban co-administration may raise the risk of bleeding.

How to manage the interaction:
Even though combining Urotek 500000 IU Injection and Apixaban may cause an interaction, it is still possible to take it if your doctor advises you to. Consult a doctor if you experience symptoms like blood in your urine or stool (or a black stool), severe bruising, prolonged nosebleeds, feeling dizzy or lightheaded, weakness or severe headache, vomiting blood or coughing up blood, heavy menstrual bleeding (in women), difficulty breathing, or chest pain. Without consulting a doctor, never stop taking any medications.
UrokinaseDeferasirox
Severe
How does the drug interact with Urotek 500000 IU Injection:
Using deferasirox together with Urotek 500000 IU Injection may increase the risk of gastrointestinal ulcers.

How to manage the interaction:
Co-administration of Urotek 500000 IU Injection with Deferasirox can possibly result in an interaction, but it can be taken if your doctor has advised it. This risk is higher in older people with certain blood disorders or low platelet counts.If you have symptoms like stomach pain, bloating, dizziness, or black stools, it's important to consult a doctor. Do not stop using any medications without a doctor's advice.
UrokinaseEnoxaparin
Severe
How does the drug interact with Urotek 500000 IU Injection:
Taking Urotek 500000 IU Injection with Enoxaparin can increase the risk or severity of bleeding.

How to manage the interaction:
Although there is a possible interaction between Enoxaparin and Urotek 500000 IU Injection, you can take these medicines together if prescribed by your doctor. If you notice any symptoms like bleeding, bruising, dizziness, black or tarry stools, weakness, vomiting, or headaches, it is important to contact a doctor right away. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Avoid cranberry juice, grapefruit juice, noni juice, pomegranate juice, and green tea.
  • Make no dietary changes without first consulting your doctor.
  • You should avoid alcohol because it increases the risk of bleeding.
  • Maintain a healthy cholesterol and triglyceride level.
  • Maintain a healthy weight and exercise routine to keep your heart healthy.

Habit Forming

No

Therapeutic Class

ANTICOAGULANT/ANTITHROMBOTIC

All Substitutes & Brand Comparisons

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Alcohol

Unsafe

Avoid the consumption of alcohol with Urotek 500000 IU Injection 1's as it may increase the risk of bleeding.

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Pregnancy

Unsafe

Urotek 500000 IU Injection 1's is not recommended during pregnancy or immediately after the delivery unless advised by the doctor. Please consult a doctor if you are pregnant or planning for pregnancy.

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Breast Feeding

Unsafe

Breastfeeding is not recommended during treatment with Urotek 500000 IU Injection 1's. Please consult a doctor if you have any concerns.

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Driving

Caution

It is unclear whether Urotek 500000 IU Injection 1's impacts your ability to drive or operate machinery. However, drive or operate machinery only if you are alert.

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Liver

Caution

Let your doctor know if you have a history of liver diseases/conditions. Your doctor will prescribe only if the benefits outweigh the risks.

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Kidney

Caution

Let your doctor know if you have a history of kidney diseases/conditions. Your doctor will prescribe only if the benefits outweigh the risks.

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Children

Unsafe

Urotek 500000 IU Injection 1's is not recommended for children as safety and effectiveness have not been established.

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Heart

Urotek 500000 IU Injection 1's should be used with caution in patients with heart conditions, as it may increase the risk of side effects. Please inform your doctor if you have any heart problems before receiving Urotek 500000 IU Injection 1's.

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Geriatrics

Caution

Urotek 500000 IU Injection 1's should be administered with caution in elderly patients due to an increased risk of side effects. Seek medical advice if you have any concerns.

FAQs

Urotek 500000 IU Injection 1's belongs to a class of drugs called antithrombotic agents used to dissolve harmful blood clots in blood vessels. It is used in conditions such as peripheral vascular thromboembolism (blood clot in a large vein), cerebral thrombosis (blood clot in venous sinuses of the brain), cerebral infarction (stroke), myocardial infarction and pulmonary embolism (blood clots in the lungs).

Urotek 500000 IU Injection 1's works by dissolving the harmful blood clots in the blood vessels. This restores the blood flow to the affected blood vessels, preventing various illnesses caused by blood clots.

Yes, Urotek 500000 IU Injection 1's raises the possibility of bleeding. Always exercise caution when engaging in activities that could result in an injury or bleeding. Notify your doctor right away if you notice any unusual bruises or bleeding.

To determine blood clotting time, tests such as platelet count, factor V assay, fibrinogen level test, prothrombin time test (PT or PT-INR), and the INR (international normalised ratio) are utilised.

If you are scheduled for surgery, please consult your doctor. The doctor may advise you to stop taking Urotek 500000 IU Injection 1's a few days before surgery because it increases the chance of bleeding during surgery.

Urotek 500000 IU Injection 1's is not recommended for use in people with severe uncontrolled high blood pressure.

Urotek 500000 IU Injection 1's may interact with certain medications such as anticoagulant medications (warfarin) and medications with platelet antiaggregant effects (aspirin, ticlopidine hydrochloride, dipyridamole). So, avoid taking these medications together. However, it is better to consult a doctor before taking any medication while on treatment with Urotek 500000 IU Injection 1's to ensure safety.

The common side effects of Urotek 500000 IU Injection 1's that may occur in some individuals such as unusual bleeding, nausea, vomiting, and loss of appetite. Most of these side effects do not necessitate medical treatment and fade away with time. Please visit your doctor if the side effects persist or worsen.

Country of origin

India

Manufacturer/Marketer address

Vill. Mouza Ogli, Suketi Road, Tehsil-Nahan, Dist-Sirmour, Himachal Pardesh Pin.173030 INDIA
Other Info - URO0280

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Santoshini Reddy GDoctor badge

Reviewed By

Santoshini Reddy G

M Pharmacy

Last Updated

Oct 22, 2025 | 2:07 PM IST

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Reference

  1. https://www.mims.com/singapore/drug/info/urokinase-green%20cross/adverse-reactions
  2. https://www.accessdata.fda.gov/drugsatfda_docs/label/2008/021846s101lbl.pdf
  3. https://www.drugs.com/drug-interactions/urokinase.html
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