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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Unipol-B Injection is used to treat bacterial infections such as urinary tract infections, meningitis, bloodstream infections, and corneal and subconjunctival eye infections caused by susceptible organisms. It contains Polymyxin B, which destroys bacterial cell membranes and kills infection-causing bacteria. Thereby, it helps treat bacterial infections. In some cases, Unipol-B Injection may cause side effects such as pain at the injection site, flushing, dizziness, and diarrhoea.

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Whats That

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Synonym :

POLYMYXIN B SULPHATE

Manufacturer/Marketer :

United Biotech Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Unipol-B Injection

Unipol-B Injection belongs to the group of medicines called antibiotics used to treat bacterial infections such as urinary tract infections, meningitis, bloodstream infections, and corneal and subconjunctival eye infections caused by susceptible organisms.

Unipol-B Injection contains Polymyxin B, which works by destroying bacterial cell membranes and killing infection-causing bacteria. Thereby, it helps treat bacterial infections.

In some cases, Unipol-B Injection may cause side effects such as pain at the injection site, flushing, dizziness, and diarrhoea. Most of these side effects may not require medical attention and resolve gradually over time. However, consult a doctor if the side effects persist or worsen.

Let the doctor know if you are allergic to any of the components in Unipol-B Injection. Consult the doctor if you are pregnant or breastfeeding. Keep your doctor informed about your health condition and medications to rule out any side effects/interactions.

Uses of Unipol-B Injection

Unipol-B Injection is used in the treatment of Bacterial infections. The detailed uses of Unipol-B Injection are as follows:<br/>• Treat bloodstream infections: Unipol-B Injection is effective against septicemia caused by resistant gram-negative bacteria such as Pseudomonas aeruginosa, Klebsiella pneumoniae, and Escherichia coli.<br/>• Manage meningitis: Unipol-B Injection is administered intrathecally to treat bacterial meningitis, especially when caused by Pseudomonas aeruginosa or Haemophilus influenzae.<br/>• Treat urinary tract infections: Unipol-B Injection helps eliminate gram-negative pathogens in complicated or hospital-acquired UTIs.<br/>• Address pulmonary infections: Unipol-B Injection is used in cases of pneumonia and pulmonary embolism caused by multidrug-resistant gram-negative bacteria.<br/>

Directions for Use

• Unipol-B Injection will be administered by a healthcare professional.• Do not self-administer it.

Medicinal Benefits

Unipol-B Injection belongs to the group of medicines called antibiotics used to treat bacterial infections such as urinary tract infections, meningitis, bloodstream infections, and corneal and subconjunctival eye infections caused by susceptible organisms. Unipol-B Injection contains Polymyxin B, which works by destroying bacterial cell membranes and killing infection-causing bacteria. Thereby, it helps treat bacterial infections.

How Unipol-B Injection Works

Unipol-B Injection contains Polymyxin B, which works by destroying bacterial cell membranes and killing infection-causing bacteria. Thereby, it helps treat bacterial infections.

Storage

• Store in a cool and dry place away from sunlight.
• Keep Unipol-B Injection out of reach and sight of children.
• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of Unipol-B Injection

As Unipol-B Injection is a parenteral formulation administered by experienced medical staff, the chance of overdose may be less. However, if you think there has been an overdose or experiencing any adverse events, get medical care right away.

Drug Warnings

Do not receive Unipol-B Injection if you are allergic to any of its components. Consult the doctor if you are pregnant or breastfeeding. Seek medical attention if you experience symptoms of kidney problems (unable to pass urine, change in how much urine you pass), nerve problems (weakness, irritation, feeling sleepy, blurred eyesight, change in balance, numbness or tingling around the mouth or in the arms or legs, or trouble breathing), or Clostridium difficile associated diarrhoea/CDAD (stomach pain, cramps, very loose, watery, or bloody stool). Let the doctor know if you are taking any prescription/non-prescription medicines, including supplements or herbal products.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Unipol-B Injection:
Co-administration of Unipol-B Injection and Vecuronium together may cause serious breathing problems.

How to manage the interaction:
Taking Unipol-B Injection with Vecuronium together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience any breathing difficulty, consult the doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Unipol-B Injection:
Co-administration of Deferasirox and Unipol-B Injection may increase the risk of kidney problems.

How to manage the interaction:
Although taking Unipol-B Injection and Deferasirox together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, swelling, breathing difficulty, bone pain, muscle pain, dizziness, confusion, or irregular heart rhythm, seek immediate medical attention. Drink plenty of water if you experience diarrhea or vomiting while taking these medications, as dehydration can potentially affect the kidneys. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Unipol-B Injection:
Taking Adefovir dipivoxil with Unipol-B Injection may increase the risk of side effects.

How to manage the interaction:
Although taking Unipol-B Injection and Adefovir dipivoxil together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience nausea, vomiting, decreased hunger, increased or decreased urine, weight gain or loss that occurs suddenly, fluid retention, swelling, difficulty breathing, bone pain, muscle pain, fatigue, weakness, dizziness, confusion, and irregular heartbeat, consult a doctor. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Unipol-B Injection:
Taking Human immunoglobulin with Polymyxin- b, may raise the risk of kidney problems.

How to manage the interaction:
Although taking Human immunoglobulin and Unipol-B Injection together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not discontinue any medications without consulting a doctor.
Polymyxin bCholera, live attenuated
Severe
How does the drug interact with Unipol-B Injection:
Taking Unipol-B Injection and Cholera together may lead to a decrease in the effectiveness of the vaccine.

How to manage the interaction:
There may be a possibility of interaction between Unipol-B Injection and Cholera, live attenuated, but it can be taken if prescribed by a doctor. It is advised not to receive the cholera vaccination until at least 14 days after finishing your Unipol-B Injection therapy in order to ensure an appropriate immune response. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Unipol-B Injection:
Co-administration of Sirolimus and Unipol-B Injection together may increase the risk or severity of kidney problems.

How to manage the interaction:
There may be a possibility of interaction between Sirolimus and Unipol-B Injection, but it can be taken if prescribed by a doctor. However, if you experience nausea, vomiting, a decrease in hunger, increased or decreased urine, weight gain or loss that occurs suddenly, fluid retention, swelling, difficulty breathing, bone pain, muscle pain, fatigue, weakness, dizziness, confusion, and irregular heartbeat, consult a doctor. Do not discontinue any medications without a doctor's advice.
Polymyxin bIodamide
Severe
How does the drug interact with Unipol-B Injection:
Co-administration of Iodamide with Unipol-B Injection may increase the risk of kidney damage.

How to manage the interaction:
Although there is a possible interaction between Unipol-B Injection and Iodamide, you can take these medicines together if prescribed by a doctor. However, contact a doctor immediately if you experience any symptoms such as nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, swelling, breathing difficulty, muscle pain, weakness, dizziness, confusion, and irregular heart rhythm. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Unipol-B Injection:
Taking Kanamycin with Unipol-B Injection can increase the risk and severity of side effects.

How to manage the interaction:
There may be a possibility of interaction between Unipol-B Injection and Kanamycin, but it can be taken if prescribed by a doctor. However, if you experience hearing loss, ringing in the ears, vertigo, difficulty breathing, nausea, vomiting, a decrease in hunger, increased or decreased urine, weight gain or loss that occurs suddenly, swelling, difficulty breathing, bone pain, muscle pain, fatigue, weakness, dizziness, confusion, and irregular heartbeat, consult a doctor. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Unipol-B Injection:
When Neomycin and Unipol-B Injection are taken together, there is an increased possibility of severe side effects.

How to manage the interaction:
Taking Unipol-B Injection with Neomycin together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience nausea, vomiting, a decrease in hunger, increased or decreased urine, weight gain or loss that occurs suddenly, fluid retention, swelling, difficulty breathing, bone pain, muscle pain, fatigue, weakness, dizziness, confusion, and irregular heartbeat, hearing loss, ringing in the ears, vertigo, consult a doctor. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Unipol-B Injection:
Co-administration of Unipol-B Injection may increase the effects of Suxamethonium when taken in combination.

How to manage the interaction:
Co-administration of Suxamethonium with Unipol-B Injection can result in an interaction, but it can be taken if a doctor has advised it. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Include whole grains, fruits, and vegetables in your diet. 
  • Taking probiotics after antibiotic treatment and eating high-fibre and prebiotic foods may help reduce side effects and support digestion.
  • Exercising regularly helps in improving overall health. 
  • Rest well, and get plenty of sleep.
  • Avoid smoking and alcohol consumption.
  • Meditation and yoga can help lower stress.
  • Avoid processed and fried food.

Habit Forming

No

Therapeutic Class

ANTIBIOTICS
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Alcohol

Consult your doctor

It is not known if alcohol interacts with Unipol-B Injection. Please consult the doctor.

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Pregnancy

Caution

The safety of polymyxin B in pregnancy has not been established. If you are pregnant or planning pregnancy, inform the doctor before receiving Unipol-B Injection.

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Breast Feeding

Caution

If you are breastfeeding, inform your doctor before receiving Unipol-B Injection. Caution is advised while administering Unipol-B Injection to lactating women.

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Driving

Consult your doctor

It is unknown if Unipol-B Injection affects your ability to drive. Drive only if you are alert.

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Liver

Consult your doctor

If you have a history of liver problems, inform the doctor before receiving Unipol-B Injection.

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Kidney

Caution

If you have a history of kidney problems, inform the doctor before receiving Unipol-B Injection.

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Children

Safe if prescribed

Unipol-B Injection may be safe for use in children if prescribed by the doctor.

Have a query?

FAQs

Unipol-B Injection is used to treat Bacterial infections.

Unipol-B Injection works by destroying bacterial cell membranes and killing infection-causing bacteria. Thereby, it helps treat bacterial infections.

Diarrhoea might be a side effect of Unipol-B Injection. Drink enough fluids and eat non-spicy food if you experience diarrhoea. Consult the doctor if the condition persists or worsens.

Unipol-B Injection may cause nerve problems. Consult the doctor if you experience weakness, irritation, change in balance, feeling sleepy, blurred eyesight, trouble breathing, numbness or tingling sensation in the arms and legs.

Unipol-B Injection will be administered by a healthcare professional. Do not self-administer.

Yes, Unipol-B Injection is safe when used only under the doctor’s supervision. However, it may cause pain at the injection site, flushing, dizziness, and diarrhoea while using it.

The common side effects of Unipol-B Injection may include pain at the injection site, flushing, dizziness, and diarrhoea. Most of these side effects may not require medical attention and resolve gradually over time. However, consult a doctor if the side effects persist or worsen.

Country of origin

India

Manufacturer/Marketer address

FC/B-1 (Extn.), Mohan Co-operative Industrial Estate Mathura Road, New Delhi - 110 044
Other Info - UNI0064

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