Twelup OD Tablet | Uses, Side Effects, Price

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Prescription Medicine

Twelup OD Tablet is used to treat peripheral neuropathy and Megaloblastic anemia caused by vitamin B12 deficiency. This medicine contains mecobalamin, which helps protect the nerves from damage and promotes blood cell production. Some common side effects include nausea, vomiting, diarrhoea, and headache.

Written By Bayyarapu Mahesh Kumar , M Pharmacy

Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

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More about the Product

Composition :

MECOBALAMIN-1500MCG

Manufacturer/Marketer :

Nexkem Pharmaceuticals Pvt Ltd

Consume Type :

Sublingual

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Twelup OD Tablet

Twelup OD Tablet belongs to the class of vitamins primarily used to treat peripheral neuropathies and megaloblastic anaemia caused by vitamin B12 deficiency. Megaloblastic anaemia is a condition in which the red blood cells are abnormally large. Peripheral neuropathy causes damage to the nerves located outside the spinal cord and brain.

Twelup OD Tablet contains Mecobalamin, a crucial B12 variant that replenishes low levels. Restored vitamin B12 levels help soothe nerve pain, support healthy cell function, and contribute to blood health and protein building.

Sometimes, Twelup OD Tablet may cause common side effects like nausea, vomiting, diarrhoea, loss of appetite, and headache. These side effects do not require medical attention and gradually resolve over time. If these side effects are persistent, please reach out to your doctor.

Do not take it if you are allergic to any component present in it; if you are unsure, check with your doctor. Inform your doctor if you are pregnant, planning a pregnancy, or are breastfeeding. Keep your doctor informed about your present and past medical history and ongoing medicines to rule out any side effects. Consumption of alcohol should be avoided as excessive alcohol consumption can interfere with B12 absorption.

Uses of Twelup OD Tablet

Twelup OD Tablet is used to treat peripheral neuropathy and megaloblastic anemia caused by vitamin B12 deficiency. The detailed uses of Twelup OD Tablet are as follows:

Treats peripheral neuropathy: Twelup OD Tablet helps repair and protect nerves damaged due to vitamin B12 deficiency, reducing numbness, tingling, and weakness.
Treats megaloblastic anemia: Twelup OD Tablet corrects anemia caused by insufficient vitamin B12, improving red blood cell formation and oxygen delivery.

Have a query?

Directions for Use

Twelup OD Tablet can be taken on an empty stomach for better absorption.
Follow your doctor’s instructions on the dosage and timing of this medication. It is often taken in the morning, at least 30 minutes before or two hours after a meal.
Place the tablet below the tongue and allow it to dissolve.
Do not break, chew, or crush it.
Do not handle the tablet with wet hands.

Key Benefits

Helps treat and prevent vitamin B12 deficiency.
Supports healthy nerve function and aids in nerve regeneration.
Improves symptoms of peripheral neuropathy such as numbness, tingling, and nerve pain.
Enhances red blood cell formation and helps prevent anemia.
Boosts energy levels and reduces fatigue associated with low vitamin B12.
Supports brain health, memory, and cognitive function.
Promotes healthy metabolism of fats and carbohydrates.
Aids in maintaining overall nervous system health.
Sublingual form allows faster absorption and better bioavailability of vitamin B12.

How Twelup OD Tablet Works

Storage

Store in a cool and dry place away from sunlight

What if I have taken an overdose of Twelup OD Tablet

Do not take more than the recommended dose. If you suspect that you might have taken an overdose of Twelup OD Tablet , seek immediate medical help.

Drug Warnings

Before taking the Twelup OD Tablet , let your doctor know about all your medical conditions, sensitivities, and medications you are using.
Also, inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding.
Do not use Twelup OD Tablet in more than prescribed doses or for a longer duration as it may cause adverse effects.
The prolonged use of larger doses of Twelup OD Tablet is not recommended for patients whose occupation requires the handling of mercury or mercury compounds.

Diet & Lifestyle Advise

Diet

Include B12-rich foods:

Animal-based products: Meat (especially liver), poultry, fish, eggs, milk, and dairy products.
Fortified foods: Some breakfast cereals, plant-based milk, and nutritional yeast.
Consider supplements: If dietary changes aren't sufficient, consult your doctor about B12 supplements. They can be oral, nasal, or injected.
Vegans and vegetarians: Pay close attention to B12 intake, as it's primarily found in animal products. Opt for fortified foods or supplements.

Lifestyle

Regular check-ups: If you are at risk (older adult, vegan/vegetarian, digestive issues), get regular B12 checks.
Limit alcohol: Excessive alcohol consumption can interfere with B12 absorption.
Healthy gut: Conditions like Crohn's disease or celiac disease can affect B12 absorption. Manage these conditions effectively.

Habit Forming

Therapeutic Class

[VITAMINS]

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Alcohol

Caution

Limit alcohol intake, as excessive alcohol consumption can interfere with B12 absorption.

Pregnancy

Consult your doctor

Please visit your doctor. There are no competent and well-controlled pregnancy studies. Your doctor will only prescribe if the benefits outweigh the risks.

Breast Feeding

Consult your doctor

Consult your doctor; there has been no significant research on the use of Twelup OD Tablet in breastfeeding/nursing mothers.

Driving

Consult your doctor

It's unclear whether Twelup OD Tablet affects driving abilities, so don't drive or operate machinery if you're having trouble concentrating or reacting.

Liver

Consult your doctor

Limited information is available on the use of Twelup OD Tablet in patients with liver disease. If you have a history of liver impairment, inform your doctor before receiving the Twelup OD Tablet . Your doctor will prescribe only if the benefits outweigh the risks.

Kidney

Consult your doctor

Limited information is available on the use of Twelup OD Tablet in patients with kidney disease. If you have a history of kidney impairment, inform your doctor before receiving the Twelup OD Tablet . Your doctor will prescribe only if the benefits outweigh the risks.

Children

Consult your doctor

There is limited information about the usage of Twelup OD Tablet in paediatric patients. Please seek medical advice. Only if the benefits greater than the risks, your doctor will prescribe Twelup OD Tablet .

Heart

Safe if prescribed

Twelup OD Tablet is generally safe for people with heart problems and may even support heart health by lowering homocysteine levels. Still, it's best to consult your doctor before starting any supplement, especially if you're on cardiac medications.

Geriatrics

Safe if prescribed

Geriatric patients can safely take Twelup OD Tablet . However, it's best to consult your doctor to confirm the right dose and rule out any interactions with other medications.

FAQs

What is the use of Twelup OD Tablet ?

Twelup OD Tablet belongs to the class of vitamins primarily used to treat peripheral neuropathies (nerve damage in the hands and feet) and megaloblastic anaemia (a blood disorder in which the red blood cells are abnormally larger than normal) caused by vitamin B12 deficiency.

How does Twelup OD Tablet work?

Twelup OD Tablet addresses B12 insufficiency by replacing the body's low levels of vitamin B12. It further benefits in treating peripheral neuropathic pain by preventing nerve cell damage. It also involves cell proliferation, blood production, and protein synthesis.

What if I miss a dose?

If you miss a dose, take it as soon as you remember. However, if it is time for the next scheduled dose, skip the missed dose and follow your usual dosage.

Can I take other medicines with Twelup OD Tablet ?

Inform your doctor about all your medications, especially if you are taking chloramphenicol, colchicine, oral diabetes medicine (metformin), drugs that reduce stomach acid, such as cimetidine, lansoprazole, omeprazole, and antibiotics. These medications may interfere with Twelup OD Tablet , causing unpleasant side effects or making Twelup OD Tablet less effective.

Which foods help treat Vitamin B12 deficiency?

Vitamin B12 sources include eggs, beef, liver, chicken, trout, salmon, tuna, clams, fortified breakfast cereal, low-fat milk, yoghurt, and cheese.

Country of origin

India

Manufacturer/Marketer address

Plot No. 288, 1st Floor, Industrial Area Phase 2, Panchkula, Haryana 134113

Other Info - TWE0012

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Author Details

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Nov 7, 2025 | 8:36 AM IST

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