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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Trypace Tablet is used to relieve pain and inflammation associated with osteoarthritis, rheumatoid arthritis, spondylosis, spondyloarthritis, and ortho-degenerative disorders. It works by blocking the action of chemical messengers that cause pain and inflammation. Besides this, it helps reduce swelling and inflammation by breaking down the abnormal proteins at the site of inflammation.
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Manufacturer/Marketer :

Alonsoa Life Sciences

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Trypace Tablet

Trypace Tablet is a combination medicine used to relieve pain and inflammation associated with osteoarthritis, rheumatoid arthritis, spondylosis, spondyloarthritis, and ortho-degenerative disorders. Pain is a symptom triggered by the nervous system, causing uncomfortable sensations in the body. Arthritis, also known as joint inflammation, is the tenderness and swelling of the joints. Symptoms include swelling, pain, and stiffness. 
 
Trypace Tablet is a combination of three drugs, namely: Aceclofenac, Paracetamol, and Trypsin chymotrypsin. Aceclofenac and Paracetamol work by blocking the effect of chemical messengers called prostaglandins by inhibiting cyclooxygenase (COX) enzymes, thereby reduces mild to moderate pain and inflammation at the injured or damaged site. Trypsin chymotrypsin breaks down the abnormal proteins at the site of inflammation, thereby reduces swelling and inflammation.
 
You are advised to take Trypace Tablet for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side-effects such as nausea, vomiting, stomach pain, loss of appetite, indigestion, and diarrhoea. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
 
Consult your doctor if you are pregnant or breastfeeding. Trypace Tablet may cause drowsiness and dizziness, so drive with caution. Trypace Tablet is not recommended for children as safety and efficacy have not been established. Avoid consuming alcohol with Trypace Tablet as it could lead to increased drowsiness and dizziness; it might also increase the risk of stomach bleeding. Keep your doctor informed about your health condition and medicines to rule out any side effects/interactions.

Uses of Trypace Tablet

Treatment of Pain and inflammation associated with musculoskeletal and joint disorders.

Directions for Use

• Trypace Tablet can be taken with food to avoid stomach upset.• Follow your doctor's instructions on the dosage and timing of this medication.• Swallow Trypace Tablet as a whole with a glass of water.• Do not break, chew, or crush it.

Medicinal Benefits

Trypace Tablet is a combination of three drugs, namely: Aceclofenac, Paracetamol, and Trypsin chymotrypsin. Trypace Tablet is used to relieve pain and inflammation associated with osteoarthritis, rheumatoid arthritis, spondylosis, spondyloarthritis, and ortho-degenerative disorders. Aceclofenac is an NSAID (Non-Steroidal Anti-Inflammatory Drug) and Paracetamol is an analgesic. Aceclofenac and Paracetamol work by blocking the effect of chemical messengers called prostaglandins by inhibiting cyclooxygenase (COX) enzymes, thereby reducing mild to moderate pain and inflammation at the injured or damaged site. Trypsin chymotrypsin is a combination of enzymes that breaks down the abnormal proteins at the site of inflammation, thereby reducing swelling and inflammation by increasing the blood supply at the affected area.

How Trypace Tablet Works

Trypace Tablet is a combination of three drugs, namely: Aceclofenac, Paracetamol, and Trypsin chymotrypsin. Aceclofenac and Paracetamol work by blocking the effect of chemical messengers called prostaglandins by inhibiting cyclooxygenase (COX) enzymes, thereby reduces mild to moderate pain and inflammation at the injured or damaged site. Trypsin chymotrypsin breaks down the abnormal proteins at the site of inflammation, thereby reduces swelling and inflammation.

Storage

Keep Trypace Tablet out of reach and sight of children.
Side effects of Trypace Tablet
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • Consume more fruits, vegetables, and cruciferous foods like cabbage, kale, and broccoli.
  • Reduced alcohol intake can enhance liver enzyme function.
  • Oxidative stress can be managed by eating foods rich in antioxidants, such as vitamins C and E.
  • Liver function tests regularly can help manage increased levels of AST.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
  • Include iron-rich foods like dark leafy vegetables, lean red meat, legumes and fish in your diet.
  • Consume vitamin C-rich foods as they aid iron absorption.
  • Limit tea, cocoa, and coffee as these can slow iron absorption.
  • Exercise regularly; however, do not overdo it.
  • Rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.
Here are the seven steps to manage medication-triggered Dyspnea (Difficulty Breathing or Shortness of Breath):
  • Tell your doctor immediately if you experience shortness of breath after taking medication.
  • Your doctor may adjust the medication regimen or dosage or give alternative medical procedures to minimize the symptoms of shortness of breath.
  • Monitor your oxygen levels and breathing rate regularly to track changes and potential side effects.
  • For controlling stress and anxiety, try relaxation techniques like deep breathing exercises, meditation, or yoga.
  • Make lifestyle changes, such as quitting smoking, exercising regularly, and maintaining a healthy weight.
  • Seek emergency medical attention if you experience severe shortness of breath, chest pain, or difficulty speaking.
  • Follow up regularly with your doctor to monitor progress, adjust treatment plans, and address any concerns or questions.

What if I have taken an overdose of Trypace Tablet

Take Trypace Tablet only as prescribed by the physician. Do not exceed the recommended dose, as it might cause an overdose. If you suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

Do not take Trypace Tablet if you are allergic to any of its contents; if you have/had severe heart problems, active or recurring peptic ulcer, gastrointestinal perforation, bleeding problems, inflammation of intestines, severe liver or kidney impairment. Inform your doctor if you have/had high blood pressure, heart problems, high cholesterol, diabetes, asthma, angina, bowel problems, blood clotting disorder, a habit of smoking, liver or kidney problems. Consult your doctor if you are pregnant or breastfeeding. Stop taking Trypace Tablet and consult your doctor immediately if you have stomach pain or any signs of bleeding in the intestine or stomach, such as blood in stools. 

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Trypace Tablet:
Co-administration of Atenolol with Trypace Tablet could increase the risk of low blood pressure.

How to manage the interaction:
Although there is a possible interaction between Atenolol and Trypace Tablet, you can take these medicines together if prescribed by a doctor. Consult a doctor if you experience excessive sweating, shortness of breath, palpitations, or chest discomfort. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Trypace Tablet:
Co-administration of Trypace Tablet and Leflunomide may increase the risk of liver problems.

How to manage the interaction:
Although there is a possible interaction between Trypace Tablet and Leflunomide, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
ParacetamolMipomersen
Severe
How does the drug interact with Trypace Tablet:
Co-administration of Mipomersen with Trypace Tablet may increase the risk or severity of liver injury.

How to manage the interaction:
There may be a possibility of interaction between Trypace Tablet and Mipomersen, but it can be taken if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
How does the drug interact with Trypace Tablet:
Co-administration of Trypace Tablet may decrease the excretion rate of Oxazepam which could result in a higher serum level.

How to manage the interaction:
Although there is a possible interaction between Oxazepam and Trypace Tablet, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Trypace Tablet:
Co-administration of Trypace Tablet and Ketoconazole may increase the risk of liver injury.

How to manage the interaction:
Although there is a possible interaction between Trypace Tablet and Ketoconazole, you can take these medicines together if prescribed by a doctor. However, if you have joint pain or swelling, fever, chills, unusual bleeding or bruising, skin rash, itching, over-tiredness, nausea, vomiting, loss of appetite, stomach pain, dark-colored urine, light-colored stools, and/or yellowing of the skin or eyes, contact a doctor immediately as these may be signs and symptoms of liver damage. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Trypace Tablet:
Co-administration of Teriflunomide with Trypace Tablet may increase the risk or severity of Liver problems.

How to manage the interaction:
Taking Trypace Tablet with Teriflunomide together can possibly result in an interaction, but it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
ParacetamolValdecoxib
Severe
How does the drug interact with Trypace Tablet:
Co-administration of Trypace Tablet and Valdecoxib may increase the risk or severity of adverse effects.

How to manage the interaction:
Although there is a possible interaction between Trypace Tablet and Valdecoxib, you can take these medicines together if prescribed by a doctor. However, if the side effects worsen, please consult a doctor.
ParacetamolLomitapide
Severe
How does the drug interact with Trypace Tablet:
Co-administration of Lomitapide and Trypace Tablet may increase the risk of severity of liver injury.

How to manage the interaction:
Although there is a possible interaction between Trypace Tablet and Lomitapide, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Trypace Tablet:
Co-administration of ketamine and Trypace Tablet may decrease the effectiveness of Ketamine which could result in a higher blood level.

How to manage the interaction:
Although taking Ketamine and Trypace Tablet together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you're feeling very sleepy or having trouble breathing, it's important to contact your doctor right away. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Physical activity helps in strengthening muscles and relieves joint stiffness. Gentle activities like 20-30minutes of walking or swimming would be helpful.
  • Performing yoga may also help in improving joint flexibility and pain management.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Get adequate sleep, as resting the muscles can help in reducing inflammation and swelling.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
  • Acupuncture, massage and physical therapy may also be helpful.
  • Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
  • Foods containing flavonoids help in reducing inflammation. These include soy, berries, broccoli, grapes and green tea.
  • Avoid smoking and alcohol consumption.

Habit Forming

No

Therapeutic Class

ANALGESICS
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Alcohol

Unsafe

Avoid consumption of alcohol while taking Trypace Tablet as it may increase drowsiness. It may also increase the risk of stomach bleeding.

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Pregnancy

Caution

Please consult your doctor if you have any concerns; your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Consult your doctor if you are breastfeeding; your doctor will decide whether Trypace Tablet can be taken by breastfeeding mothers or not.

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Driving

Caution

Trypace Tablet may cause dizziness and drowsiness. Do not drive or operate machinery unless you are alert.

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Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this. Trypace Tablet is not recommended for patients with severe hepatic impairment.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this. Trypace Tablet is not recommended for patients with severe renal impairment.

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Children

Unsafe

Trypace Tablet is not recommended for children as safety and effectiveness have not been established.

Have a query?

FAQs

Trypace Tablet is used to relieve pain and inflammation associated with musculoskeletal and joint disorders.

Trypace Tablet contains Aceclofenac, Paracetamol, and Trypsin chymotrypsin. Aceclofenac and Paracetamol work by blocking the effect of chemical messengers that cause pain and inflammation. Trypsin chymotrypsin breaks down the abnormal proteins at the site of inflammation, thereby reducing swelling and inflammation.

Trypace Tablet is used to reduce and relieve pain and inflammation associated with osteoarthritis, rheumatoid arthritis, spondylosis, spondyloarthritis, and ortho-degenerative disorders. Arthritis is tenderness and swelling in the joints.

Do not take any other medicines for pain relief such as NSAIDs along with Trypace Tablet unless prescribed by the doctor as it might increase the risk of side effects.

Avoid exceeding the dose and duration advised by the doctor. Taking more than the daily dose of Trypace Tablet might cause serious liver damage or allergic reactions like rash, difficulty in breathing, and swelling of the face, throat, and mouth. Therefore, Trypace Tablet should not be taken for longer durations unless prescribed by the doctor.

Avoid taking Trypace Tablet if you have ulcers in the stomach or intestines, bleeding problems, or heart problems. Talk to your doctor if you have any concerns.

Please consult your doctor if are pregnant or planning pregnancy before taking Trypace Tablet . Your doctor will prescribe Trypace Tablet only if the benefits outweigh the risks.

Trypace Tablet should be taken as advised by the doctor. It is preferably taken with food to avoid stomach upset.

Yes, Trypace Tablet is a painkiller as well as anti-inflammatory drug. It contains aceclofenac and paracetamol which possess pain relieving action.

Trypace Tablet should be avoided by patients with severe kidney or liver problems. Also, inform your doctor if you have heart-related diseases, hypertension (high blood pressure) or bleeding disorder, etc.

Trypace Tablet may cause side effects such as nausea, vomiting, stomach pain, diarrhoea, loss of appetite, indigestion and heartburn. If these side effects persist or worsen, please consult your doctor.

Trypace Tablet may be used or recommended to provide relief from tooth pain and swelling after a tooth extraction. However, do not self-medicate as it may cause unwanted side effects.

No, there are no reports of Trypace Tablet addiction in patients.

Trypace Tablet should be continued for as long as it is advised by your doctor. It can be discontinued if you are using it for short-term when your pain is relieved.

Yes, the use of Trypace Tablet can cause dizziness (feeling faint, lightheaded, weak, or unsteady) in some patients. If you experience dizziness or lightheadedness, it is best to take rest for some time and resume once you feel better.

Yes, the long-term use of Trypace Tablet can cause damage to the kidneys. Normal kidneys produce prostaglandins, a chemical that protects them from damage. Long term use of painkillers lowers the prostaglandins levels in the body leading to kidney damage. Therefore, painkillers are not recommended to patients with underlying kidney disease.

Trypace Tablet contains Paracetamol, which is known to harm the liver especially when taken in more than recommended doses. Also, avoid alcohol consumption while taking Trypace Tablet , as it may further increase the risk of liver damage. Also, Trypace Tablet is preferably avoided in patients with underlying liver disease. If you notice any early signs and symptoms of liver damage such as yellow skin or eyes, dark urine, fever, stomach pain, nausea, vomiting, loss of appetite, rash, fatigue (overtiredness) and abnormal liver enzymes, contact your doctor immediately.

It may take about an hour to experience the first benefit of pain relief after taking Trypace Tablet .

If you forget to take a dose of Trypace Tablet , take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take the next scheduled dose in the prescribed time. Do not double the dose to make up for the missed one as this may increase the risk of side effects.

No, taking a higher than the recommended dose may not be more effective, rather it may increase the risk of toxicity and serious side effects. If your symptoms are not relieved or there is an increased severity of your symptoms after using the recommended doses, please consult your doctor.

Trypace Tablet is contraindicated in patients with known allergy to any of its ingredients. Patients with a history of stomach ulcers or active, recurrent stomach ulcer/bleeding should ideally avoid taking Trypace Tablet . Additionally, patients with a history of high blood pressure, heart failure, and kidney or liver disease, should also avoid taking Trypace Tablet .

Country of origin

India

Manufacturer/Marketer address

G-2,SOMASHIVAM-7, MANSAROUR, BHIWANDI MUMBAI-421305
Other Info - TRY0146

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