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  3. Trogyl Injection 100 ml

Trogyl Injection 100 ml, Pack of 1 INJECTION
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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy

Trogyl Injection is an antibacterial medication used in the treatment of bone, skin and skin structure, blood, joint, abdomen, central nervous system, respiratory, gynaecological infections, meningitis, and endocarditis. This medicine inhibits the bacterial growth by destroying the DNA of the infection causing bacteria. You may experience common side effcts like nausea, vomiting, diarrhoea, constipation, and injection site reaction.

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Composition :

METRONIDAZOLE-0.5%W/V

Manufacturer/Marketer :

Amanta Healthcare Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Trogyl Injection

Trogyl Injection belongs to a group of medicines known as antibacterial agents used to treat severe bacterial infections of the bone, skin and skin structure, blood, joint, abdomen, central nervous system, respiratory, and gynaecological systems, meningitis (infection of the membranes that surround the brain and spinal cord), and endocarditis (infection of the heart lining and valves). 

Trogyl Injection contains Metronidazole, which suppresses protein synthesis by interacting with DNA and causing helical DNA structure loss and strand breakage. As a result, it induces cell death in susceptible organisms. Thus, Trogyl Injection treats bacterial infections.

Trogyl Injection will be administered by a healthcare professional; do not self-administer. Some common side effects of Trogyl Injection are nausea, vomiting, diarrhoea, constipation, and injection site reaction. These side effects are temporary and may resolve after some time. However, if any of the side effects persist or worsen, contact the doctor.

Let your doctor know if you are allergic to metronidazole. Consult your doctor if you are pregnant, planning to get pregnant, or if you are breastfeeding. Do not operate heavy machinery or drive after taking Trogyl Injection as it may cause dizziness and drowsiness. Avoid consumption of alcohol while on treatment with Trogyl Injection as it may cause unpleasant side effects.

Uses of Trogyl Injection

Trogyl Injection used in the treatment of bacterial infections. The detailed uses of Trogyl Injection are as follows: <br/>• Treatment of Infections: Trogyl Injection effectively treats various infections, including intra-abdominal, skin, gynecologic, septicemia, bone and joint, CNS, respiratory tract, and endocarditis, by eliminating anaerobic bacteria and parasites, stopping their growth, and alleviating symptoms.<br/>• Surgical Prophylaxis: Trogyl Injection is used as a surgical prophylaxis to prevent postoperative infections, particularly for surgeries involving the gastrointestinal tract.<br/>• Management of Clostridium Difficile Infection: Trogyl Injection is used to manage severe Clostridium difficile infections, especially when oral medication is not possible.<br/>• Amoebic Dysentery Treatment: Trogyl Injection is used to treat amoebic dysentery, a severe intestinal infection caused by the Entamoeba histolytica parasite.<br/>• Combination Therapy: Trogyl Injection is often used in combination with other antibiotics to treat serious infections, offering a broad spectrum of action and enhancing treatment effectiveness.<br/>

Directions for Use

• Follow your doctor's instructions on the dosage and timing of this medication to ensure safe and effective use.• Trogyl Injection will be administered by the doctor or healthcare professional.• Do not self-administer.

Medicinal Benefits

Trogyl Injection belongs to a group of medicines known as anti-bacterial agents used to treat severe bacterial infections of the bone, skin and skin structure, blood, joint, abdomen, central nervous system, gynecologic, respiratory infections, meningitis (infection of the membranes that surround the brain and spinal cord), and endocarditis (infection of the heart lining and valves). Trogyl Injection contains Metronidazole, which suppresses protein synthesis by interacting with DNA and causes helical DNA structure loss and strand breakage. As a result, it induces cell death in susceptible organisms. Thereby, Trogyl Injection treats bacterial infections.

How Trogyl Injection Works

Trogyl Injection contains Metronidazole, which suppresses protein synthesis by interacting with DNA and causing helical DNA structure loss and strand breakage. As a result, it induces cell death in susceptible organisms. Thus, Trogyl Injection treats bacterial infections.

Storage

• Store in a cool and dry place away from sunlight.• Keep out of sight and reach of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of Trogyl Injection

A health care professional administers Trogyl Injection in a hospital setting. Hence, the chances of overdose are less. Symptoms of overdose may include nausea, vomiting, loss of muscle coordination, numbness, pain, burning, or tingling in your hands or feet, and seizures. Your doctor may take necessary measures if an overdose is suspected.

Drug Warnings

Do not take Trogyl Injection if you are allergic to any of the components. Consult your doctor if you are pregnant, plan to get pregnant or if you are breastfeeding. Do not operate heavy machinery or drive after taking Trogyl Injection as it may cause dizziness and drowsiness. Inform your doctor if you have bone marrow depression/low blood count, kidney impairment, CNS disorder, liver or heart problems, peripheral neuropathy, epilepsy, Crohn's disease (a condition in which the body attacks the lining of the digestive tract), yeast infection, oedema (swelling), or blood disorders.

Diet & Lifestyle Advise

  • It would be best to take probiotics after taking the full course of Trogyl Injection to restore healthy bacteria in the intestine that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like yoghurt, cheese, sauerkraut and kimchi can help restore the intestine's good bacteria.
  • Include more fibre-enriched food in your diet. This food can be easily digested by gut bacteria, which helps stimulate their growth. Whole grains like whole-grain bread and brown rice should also be included in the diet.
  • Avoid intake of alcoholic beverages with Trogyl Injection as it can make you dehydrated and affect your sleep. This can make it harder for your body to aid Trogyl Injection in fighting off infections.

Habit Forming

No

Therapeutic Class

ANTIBIOTICS

Trogyl Injection Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Unsafe

You are recommended not to consume alcohol along with Trogyl Injection to avoid unpleasant side effects such as stomach pain, nausea, vomiting, flushing, and headache.

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Pregnancy

Caution

Please consult your doctor. Trogyl Injection should be used in pregnant women only if clinically needed, and the benefits outweigh the risks.

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Breast Feeding

Caution

Consult your doctor if you are a nursing mother. Your doctor will weigh the benefits and potential risks before prescribing Trogyl Injection .

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Driving

Caution

Trogyl Injection may cause dizziness and drowsiness; thus, avoid operating machinery or driving vehicles unless you are alert.

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Liver

Caution

Trogyl Injection to be taken with caution, especially if you have a history of liver diseases/conditions. Your doctor may adjust your dose depending on your liver condition.

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Kidney

Caution

Trogyl Injection to be taken with extreme caution, especially if you have a history of kidney diseases/conditions. Your doctor may adjust your dose depending on your kidney condition.

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Children

Consult your doctor

Limited information about the use of Trogyl Injection in paediatric patients. Please seek medical advice. Your doctor will weigh the benefits and risks before prescribing this medicine to your child.

Have a query?

FAQs

Trogyl Injection belongs to a group of medicines known as antibacterial agents used to treat severe bacterial infections of the bone, skin and skin structure, blood, joint, abdomen, central nervous system, respiratory, and gynaecological systems, meningitis (infection of the membranes that surround the brain and spinal cord), and endocarditis (infection of the heart lining and valves).

Trogyl Injection suppresses protein synthesis by interacting with DNA, causing helical DNA structure loss and strand breakage. As a result, it induces cell death in susceptible organisms, treating bacterial infections.

Caution should be exercised. Trogyl Injection may enhance the anticoagulant activity of warfarin and other oral anticoagulants by extending prothrombin time. Inform your doctor if you are taking such medications.

No. Trogyl Injection is an antibacterial medicine that acts only against bacterial infections, not viral infections like the common cold and flu.

Trogyl Injection should only be used to treat or prevent infections that have been proven or are strongly suspected to be caused by susceptible anaerobic bacteria.

Extreme caution should be exercised while using Trogyl Injection in patients with severe liver damage, blood formation disorder, brain, spinal cord or nervous disease. So, let your doctor know if you have any of these conditions.

Country of origin

India

Manufacturer/Marketer address

8th Floor, Shaligram Corporates, C. J. Marg, Ambli, Ahmedabad 380058 Gujarat, India
Other Info - TRO0175

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Santoshini Reddy GDoctor badge

Reviewed By

Santoshini Reddy G

M Pharmacy

Last Updated

Jul 18, 2025 | 7:01 AM IST

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Reference

  1. https://dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?setid=d46870f5-e2b1-46bd-8413-4a0a8bcf3175&amp;type=display
  2. https://www.medicines.org.uk/emc/files/pil.13293.pdf
  3. https://www.medicines.org.uk/emc/product/1842/smpc#gref
  4. https://www.nhs.uk/medicines/metronidazole/about-metronidazole/
  5. https://www.drugs.com/drug-interactions/metronidazole-index.html?filter=3

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