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  3. Trofentyl OTFC Tablet 1's

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Trofentyl OTFC Tablet 1's, Pack of 1 Tablet
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Written By Lakshmithulasi Yarragunta ,
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Trofentyl OTFC Tablet is used to treat pain. It contains Fentanyl, which works by blocking a chemical messenger in the brain responsible for causing pain. Hence, it changes how the brain and nervous system respond to pain. Common side effects of Trofentyl OTFC Tablet are dizziness, sleepiness, increased or decreased blood pressure, and irregular heartbeat. This medicine is not recommended for children below 18 years of age.
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Synonym :

FENTANYL CITRATE

Composition :

FENTANYL-200MCG

Manufacturer/Marketer :

Troikaa Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Trofentyl OTFC Tablet

Trofentyl OTFC Tablet belongs to a class of medicines known as 'opioid analgesics,' primarily used to relieve pain. It is used to treat breakthrough pain (sudden episodes of pain occurring despite treatment with pain medication) in cancer patients. Pain can be temporary (acute) or long-lasting (chronic) in nature. Acute pain is caused by damage to the tissues of the muscle, bone, or other organs for a short time. Chronic pain lasts for a long duration and is caused due to pathologies like nerve damage and osteoarthritis.

Trofentyl OTFC Tablet contains Fentanyl. It works by blocking a chemical messenger in the brain responsible for causing pain. Hence, changing the way the brain and nervous system respond to pain.

Trofentyl OTFC Tablet should be used as recommended. Trofentyl OTFC Tablet may cause certain side effects such as dizziness, sleepiness, increased or decreased blood pressure, and irregular heartbeat in some cases. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently. 

Trofentyl OTFC Tablet should be avoided if you are allergic to opioids or any ingredients of Trofentyl OTFC Tablet.  Inform your doctor before taking Trofentyl OTFC Tablet if you have respiratory disorders, heart diseases, high blood pressure, and liver or kidney disease. Avoid consuming alcohol along with Trofentyl OTFC Tablet as it could lead to increased dizziness. Do not take Trofentyl OTFC Tablet for a prolonged time as it may lead to mental or physical dependence on Trofentyl OTFC Tablet. This medicine is not recommended for children below 18 years of age. Do not use this medicine if you have used an MAO inhibitor in the past 14 days, as it this combination may cause serious interaction. Blood pressure and cardiovascular (heart) status should be monitored closely during the treatment with Trofentyl OTFC Tablet, especially in people affected with high blood pressure and a history of heart failure.

Uses of Trofentyl OTFC Tablet

Trofentyl OTFC Tablet is used in the treatment of Pain. The detailed use of Trofentyl OTFC Tablet is as follows:<br/>• Manage breakthrough cancer pain: Trofentyl OTFC Tablet provides rapid relief for severe pain episodes in cancer patients who are already receiving and tolerant to around-the-clock opioid therapy, by delivering fentanyl through the oral mucosa for fast absorption.<br/>

Directions for Use

• Follow your doctor's instructions regarding the dosage and duration.• Place the medication in your mouth between the cheeks and gums and actively suck on the medication.• Move the medication along the cheeks in your mouth occasionally. Do not chew or swallow as a whole. Do not eat or drink anything while the lozenge is in your mouth.

Medicinal Benefits

Trofentyl OTFC Tablet belongs to a class of drugs known as 'opioid analgesics,' containing Fentanyl, primarily used to relieve pain. It is used to treat breakthrough pain (sudden episodes of pain occurring despite treatment with pain medication) in cancer patients. It is also used as an anaesthetic agent for short operations and relieves pain in conditions like rheumatoid arthritis and osteoarthritis and pain affecting the joints and muscles. It works by blocking a chemical messenger in the brain responsible for causing pain. Hence, changing the way the brain and nervous system respond to pain.

How Trofentyl OTFC Tablet Works

Trofentyl OTFC Tablet contains Fentanyl. It works by blocking a chemical messenger in the brain responsible for causing pain. Hence, changing the way the brain and nervous system respond to pain.

Storage

• Store in a cool and dry place away from sunlight.• Keep Trofentyl OTFC Tablet out of the sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Trofentyl OTFC Tablet
  • Stay hydrated by drinking plenty of water.
  • Avoid dairy product such as cheese, milk, yogurt and ice cream.
  • Maintain healthy weight and exercise daily.
  • Following a low-calcium diet can help reduce hypercalcemia symptoms.
  • Maintaining adequate hydration will help you control your magnesium levels and improve your general health.
  • Maintain a diet high in magnesium-rich foods such as spinach, almonds, chickpeas and brown rice.
  • Limit your alcohol intake because too much of it lowers your magnesium levels.
  • Plan blood testing on a regular basis to monitor magnesium levels.
  • Consume controlled amounts of salt to raise sodium levels.
  • Eat fresh fruits like apples, berries, oranges, mangoes, and bananas.
  • Include fresh vegetables like broccoli, sweet potatoes, beets, okra, spinach, peppers, carrots, and edamame.
  • Choose frozen vegetables without added butter or sauce.
  • Drink electrolyte beverages like sports drinks or electrolyte solutions to replenish sodium and other electrolytes.
  • Avoid excessive salt intake, but allow for controlled increases as needed.
  • Monitor and manage underlying health conditions that may contribute to hyponatremia.
  • Eat fatty fish rich in omega-3 fatty acids to reduce inflammation.
  • Add whole grains such as brown rice, quinoa, and whole wheat bread to your diet for a nutritional boost.
  • Add nuts and seeds like almonds, walnuts, chia seeds for anti-inflammatory benefits.
  • Eat dark leafy greens like spinach, kale, collard greens for antioxidants.
  • Include berries like blueberries, strawberries, raspberries for anti-inflammatory properties.
  • Rest and take a break from usual activities.
  • Apply ice for 15-20 minutes, 3 times a day to reduce pain and inflammation.
  • Use compression with a stretchable bandage or wrap to lessen swelling and provide support.
  • Avoid strenuous activities and rest the affected area.
  • Try light stretching with gentle exercises to maintain flexibility.
  • Consider OTC pain medications like ibuprofen or acetaminophen but consult a doctor before taking any medication.
  • Gently massage the affected area using your hands or a massager.
  • Light exercises such as walking or climbing stairs may help the muscles return to normal.
  • Apply heat/ice to the affected area.
  • Drink electrolyte-rich fluids.
  • Take pain reliever medicines such as ibuprofen or paracetamol.
  • Apply an ice pack for 15 minutes multiple times a day during the first 48 hours. Then, use a heating pad or take warm shower.
  • Gently stretch the neck and massage to relieve pain.
  • Good posture and gentle exercise may help to prevent it.
  • Maintain proper sleep hygiene.

What if I have taken an overdose of Trofentyl OTFC Tablet

Please do not exceed the recommended dose, as it might cause an overdose. Signs and symptoms of an overdose of Trofentyl OTFC Tablet may include excessive drowsiness or sleepiness, slow or shallow breathing, difficulty breathing, cold, clammy skin, narrowing or widening of the pupils (black circles in the middle of the eyes), unable to respond or wake up, slowed heartbeat, and unusual snoring. Seek immediate medical attention if you observe any symptoms or think you have taken too much. Do this even if there are no signs of discomfort or poisoning.

Drug Warnings

Do not take Trofentyl OTFC Tablet if you are allergic to opioids or any ingredients of Trofentyl OTFC Tablet. Inform your doctor if you have respiratory disorders, heart diseases, high blood pressure, and liver or kidney disease or hypothyroidism (underactive thyroid). Do not take Trofentyl OTFC Tablet for a prolonged time, Trofentyl OTFC Tablet contains fentanyl that may lead to mental or physical dependence on Trofentyl OTFC Tablet. Do not take Trofentyl OTFC Tablet if you are pregnant or breastfeeding, as it may cause adverse effects on the baby. Trofentyl OTFC Tablet is not recommended for children below 18 years of age. Do not use this medicine if you have used an MAO inhibitor in the past 14 days, as a dangerous drug interaction could occur. Trofentyl OTFC Tablet should be taken with extreme caution in patients who have a history of alcoholism or drug abuse. Avoid consuming alcohol while on this medication, as it can lead to excessive sleepiness. Blood pressure and cardiovascular (heart) status should be monitored closely during the treatment with Trofentyl OTFC Tablet, especially in people affected with high blood pressure and a history of heart failure.

Drug-Drug Interactions

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FentanylSafinamide
Critical
FentanylLinezolid
Critical

Drug-Drug Interactions

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FentanylSafinamide
Critical
How does the drug interact with Trofentyl OTFC Tablet:
Taking Safinamide with Trofentyl OTFC Tablet can increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Safinamide with Trofentyl OTFC Tablet is not recommended as it can result in an interaction, but it can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination(seeing and hearing things that do not exist), increased heart rate, fever, excessive sweating, muscle pain, stomach cramps, vomiting, and loose stools. Do not discontinue any medications without consulting your doctor.
FentanylLinezolid
Critical
How does the drug interact with Trofentyl OTFC Tablet:
Taking Linezolid with Trofentyl OTFC Tablet may increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Although there is an interaction between Linezolid and Trofentyl OTFC Tablet, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, fever, excessive sweating, muscle pain, stomach cramps, vomiting, and diarrhoea. Do not discontinue any medications without consulting your doctor.
FentanylMifepristone
Critical
How does the drug interact with Trofentyl OTFC Tablet:
Taking Trofentyl OTFC Tablet and mifepristone may significantly increase the blood levels of Trofentyl OTFC Tablet, which may increase the risk of side effects.

How to manage the interaction:
Although there is an interaction between mifepristone and Trofentyl OTFC Tablet, they can be taken together if advised by a doctor. Do not stop using any medications without talking to your doctor.
FentanylChlorpromazine
Severe
How does the drug interact with Trofentyl OTFC Tablet:
Coadministration of Trofentyl OTFC Tablet and chlorpromazine can cause side effects.

How to manage the interaction:
Taking Trofentyl OTFC Tablet and Chlorpromazine together can result in an interaction, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience drowsiness, difficulty concentrating, and impaired judgment. Do not discontinue any medications without consulting a doctor.
FentanylEslicarbazepine
Severe
How does the drug interact with Trofentyl OTFC Tablet:
Eslicarbazepine can lower the levels of Trofentyl OTFC Tablet in the blood, decreasing the effectiveness of Trofentyl OTFC Tablet in treating pain.

How to manage the interaction:
Although taking Eslicarbazepine and Trofentyl OTFC Tablet can possibly result in an interaction, they can be taken together if prescribed by your doctor. However, if you experience body aches, abdominal cramping, diarrhoea, sneezing, fever, chills, or flushing, consult your doctor immediately. Do not stop taking any medications without consulting your doctor.
FentanylBuspirone
Severe
How does the drug interact with Trofentyl OTFC Tablet:
Taking buspirone along with Trofentyl OTFC Tablet can result in significant adverse effects such as respiratory difficulty, unconsciousness.

How to manage the interaction:
Concomitant administration of buspirone alongside Trofentyl OTFC Tablet can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience drowsiness, difficulty concentrating, or impaired judgment, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
FentanylFluvoxamine
Severe
How does the drug interact with Trofentyl OTFC Tablet:
Taking Trofentyl OTFC Tablet with fluvoxamine may increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Although taking Trofentyl OTFC Tablet with Fluvoxamine can result in an interaction, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, fever, excessive sweating, shivering, muscle pain, stomach cramps and diarrhoea. Do not discontinue any medications without consulting your doctor.
FentanylClotrimazole
Severe
How does the drug interact with Trofentyl OTFC Tablet:
Coadministration of Trofentyl OTFC Tablet with clotrimazole may increases the blood levels of Trofentyl OTFC Tablet.

How to manage the interaction:
Taking Clotrimazole with Trofentyl OTFC Tablet may possibly result in an interaction, but they can be taken together if prescribed by your doctor. However, if you experience dizziness, fainting, confusion, excessive drowsiness, a slow heart rate, shallow or difficult breathing, and/or shortness of breath, consult your doctor immediately. Do not discontinue any medication without consulting your doctor.
FentanylVerapamil
Severe
How does the drug interact with Trofentyl OTFC Tablet:
Coadministration of Trofentyl OTFC Tablet with verapamil may significantly increase the blood levels and effects of Trofentyl OTFC Tablet.

How to manage the interaction:
Although taking Trofentyl OTFC Tablet together with Verapamil can result in an interaction, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience dizziness, confusion, excessive sleepiness, or difficulty breathing. Do not stop taking any medication without consulting a doctor.
FentanylBupropion
Severe
How does the drug interact with Trofentyl OTFC Tablet:
Taking Trofentyl OTFC Tablet with bupropion may increase the risk of seizures (fits).

How to manage the interaction:
Co-administration of bupropion along with Trofentyl OTFC Tablet can lead to an interaction, but it can be taken if recommended by a doctor. Do not stop using any medications without talking to your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Do not go for heavy exercise as it may increase your joint pain in arthritis. Instead, you can do stretching and low-impact aerobic exercises like walking on a treadmill, bike riding, and swimming. You can also strengthen your muscles by lifting light weights.
  • In the chronic condition of arthritis or joint pain, including fish like salmon, trout, tuna, and sardines. These fishes are enriched with omega-3 fatty acids that have a minimum level of chemicals called cytokines, which ramp up inflammation.
  • Your sitting posture is important, especially when you have pain and inflammation. Try to sit as little as possible, and only for a short duration of time. Long-term immobility is harmful in conditions like arthritis.  Use back support like a rolled-up towel to minimise pain at the back of your spine curve. Keep your knees and hips at a right angle. Besides this, you can also use a footrest if required.
  • Include a diet rich in whole grains, vegetables, and fruits. This is a healthier option than eating many simple carbohydrates in processed foods.

Habit Forming

No

Therapeutic Class

NARCOTIC (OPIOID) ANALGESIC
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Alcohol

Unsafe

Consumption of alcohol while using Trofentyl OTFC Tablet may worsen dizziness or drowsiness. Besides this, it can also damage your liver if taken for a longer duration. So, avoid or limit intake of alcoholic beverages while on treatment with Trofentyl OTFC Tablet.

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Pregnancy

Unsafe

Trofentyl OTFC Tablet is a pregnancy category C drug. It is not recommended for use in pregnancy as it may harm your foetus. Hence, if you are pregnant or planning pregnancy, inform your doctor before taking Trofentyl OTFC Tablet. Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Breast Feeding

Unsafe

It may be unsafe to use during breastfeeding as it may cause sleepiness and decreased heart rate in the breastfeeding child. Hence, if you are a breastfeeding mother, inform your doctor before taking Trofentyl OTFC Tablet. Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Driving

Unsafe

Trofentyl OTFC Tablet is known to cause dizziness, sleepiness, and drowsiness. So, do not drive or operate any machinery.

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Liver

Caution

Trofentyl OTFC Tablet to be taken with caution, especially if you have a history of liver disease. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

bannner image

Kidney

Caution

Trofentyl OTFC Tablet to be taken with caution, especially if you have a history of kidney disease Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

bannner image

Children

Unsafe

Trofentyl OTFC Tablet is not recommended for children below the age of 18 years.

Have a query?

FAQs

Trofentyl OTFC Tablet is used to treat pain.

Trofentyl OTFC Tablet contains Fentanyl which works by blocking a chemical messenger in the brain responsible for causing pain. Hence, changing the way the brain and nervous system respond to pain.

Yes, Trofentyl OTFC Tablet sometimes may make you breathe more slowly than usual or can cause shortness of breath. If you feel so, please inform your doctor immediately. Also, people with any breathing problems should inform their doctor before starting Trofentyl OTFC Tablet.

Elderly patients (aged more than 65 years) are more likely to have confusion and sleepiness or age-related health issues, which may require caution and an adjustment in the dose for patients taking Trofentyl OTFC Tablet. So, it is better to consult a doctor before taking this medicine.

Trofentyl OTFC Tablet is a habit-forming drug. It is not likely to be addictive if you take it for 2-4 weeks. However, if the doctor has prescribed you for more than 2-4 weeks, your doctor may reduce your dose before completely stopping it.

Do not stop taking Trofentyl OTFC Tablet until instructed by your doctor. You may get side effects like confusion, depression, nervousness, sweating, and diarrhoea. Your doctor may lower the dose of Trofentyl OTFC Tablet if using it for more than 2-4 weeks of treatment to reduce side effects.

Country of origin

India

Manufacturer/Marketer address

Troikaa Pharmaceuticals Ltd., Registered Office: , 'Commerce House - 1', Satya Marg, Bodakdev, Ahmedabad-380 054. Gujarat, India.
Other Info - TRO0329

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Author Details

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 18, 2025 | 6:21 PM IST

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Reference

  1. https://medlineplus.gov/druginfo/meds/a605043.html
  2. https://pubchem.ncbi.nlm.nih.gov/compound/Fentanyl
  3. https://www.drugs.com/fentanyl.html
  4. https://www.fda.gov/drugs/postmarket-drug-safety-information-patients-and-providers/fentanyl-buccal-tablets-marketed-fentora-information

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