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Trivon Tablet is an antidepressant medicine used in the treatment of moderate to severe depression. This medicine contains tranylcypromine, which works by preventing the breakdown of the levels of serotonin and noradrenaline in the brain, thus helping treat depression. You may experience common side effects like dizziness, dry mouth, insomnia, headache, and constipation.

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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Manufacturer/Marketer :

Intas Pharmaceuticals Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Trivon Tablet

Trivon Tablet is a prescription oral medicine used to treat major depressive disorder, particularly in adults who have not responded well to other antidepressant treatments. It belongs to a class of medications called monoamine oxidase inhibitors (MAOIs), which help balance certain natural chemicals in the brain to improve mood and overall well-being.

To get the best results, you must take Trivon Tablet consistently every day exactly as prescribed by your doctor. You can take Trivon Tablet with or without food; however, you will need to follow a strict low-tyramine diet during your treatment. Avoiding aged cheeses, cured meats, and fermented foods is essential to prevent dangerous rises in blood pressure.

While taking Trivon Tablet , you may experience mild side effects like dry mouth, sleep problems, or mild dizziness when standing up. However, if you experience severe headaches, a fast heart rate, chest pain, or changes in vision, you must contact your doctor immediately as these can be signs of a serious reaction.

Before starting Trivon Tablet , tell your doctor if you have a history of heart disease, high blood pressure, liver damage, or kidney problems. Do not take Trivon Tablet if you have a tumor of the adrenal gland (pheochromocytoma, a rare tumor that can cause dangerously high blood pressure), severe cardiovascular disease, or if you are currently taking other antidepressants.

Trivon Tablet can interact dangerously with many common over-the-counter and prescription drugs, as well as alcohol and tobacco, leading to severe blood pressure spikes or a serious condition called serotonin syndrome. If you are pregnant, planning to breastfeed, or are an elderly patient, discuss the risks and benefits with your doctor before starting treatment.

Uses of Trivon Tablet

Trivon Tablet is used in the treatment of depression. The detailed uses of Trivon Tablet are as follows:

  • Treatment-Resistant Depression: Trivon Tablet helps treat severe depression in people who have not experienced adequate relief with other antidepressant medicines, helping improve mood and overall emotional well-being.
  • Major Depressive Disorder: It helps relieve persistent feelings of sadness, loss of interest in daily activities, and low energy associated with clinical depression.
  • Depressive Symptoms: It helps improve motivation, concentration, and day-to-day functioning in individuals affected by depression.

Key Benefits

Trivon Tablet helps improve mood and emotional well-being in people with depression, particularly when other treatments have not been effective. By helping restore the balance of certain brain chemicals, it supports better daily functioning and overall quality of life.
Benefits may include:

  • Helps improve mood and reduce symptoms of depression.
  • Supports greater emotional stability and overall mental well-being.
  • May increase energy levels and reduce feelings of physical and mental fatigue.
  • Helps improve sleep patterns and promote more restful sleep.
  • Supports renewed interest in daily activities, hobbies, and social interactions.
  • Helps improve overall quality of life when taken as prescribed under medical supervision.
     

Directions for Use

  • Trivon Tablet can be taken with or without food, as advised by the doctor. However, avoid taking it with foods and beverages rich in tyramine, such as aged cheese, cured meat, fermented food, red wine, and tap beer, as this may significantly increase blood pressure.
  • Typically, it is taken twice daily. However, your doctor will adjust the dose based on how well you respond to this medication and any side effects you experience.
  • Swallow Trivon Tablet as a whole with a glass of water.
  • Do not break, chew, or crush it.

How Trivon Tablet Works

Trivon Tablet works by blocking a natural enzyme in the body called monoamine oxidase. This enzyme is responsible for breaking down key chemicals in your brain, such as serotonin, norepinephrine, and dopamine. These chemicals play an important role in regulating your mood, energy, and emotions. It stops this enzyme from working, which allows these beneficial chemicals to remain in the brain for a longer period. By increasing the levels of these natural chemicals, Trivon Tablet helps brain cells send and receive signals more effectively, which gradually relieves the symptoms of depression and helps stabilize your mood.
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Alcohol

Unsafe

There can be a reaction of alcohol with Trivon Tablet . Use of Trivon Tablet with alcohol is hence not recommended. Please consult your doctor if you have any concerns.

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Pregnancy

Caution

Trivon Tablet is not recommended for use during pregnancy unless absolutely indicated. Please consult your doctor if you have any concerns.

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Breast Feeding

Caution

Trivon Tablet passes in breast milk and should be used with caution during breastfeeding. Please consult your doctor if you have any concerns.

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Driving

Unsafe

Trivon Tablet may cause drowsiness or dizziness. Exercise caution and do not drive or operate machinery unless you are alert.

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Liver

Caution

Exercise caution before using Trivon Tablet in case of liver conditions. Please consult your doctor to address any concerns.

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Kidney

Caution

Exercise caution before using Trivon Tablet in case of kidney problems. Please consult your doctor to address any concerns.

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Children

Unsafe

Trivon Tablet is not recommended for use in children below 18 years of age. Please consult your physician if you have any concerns.

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Heart

Caution

Trivon Tablet should be taken with caution in patients with heart problems. Please inform your doctor if you have any pre-existing heart problems before using Trivon Tablet .

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Geriatrics

Caution

Trivon Tablet should be given with caution in elderly patients due to an increased risk of side effects. Seek medical advice before using Trivon Tablet .

What if I have taken an overdose of Trivon Tablet

In case of an accidental overdose, seek emergency medical attention or contact a poison control center immediately. Symptoms of an overdose can be severe and may include extreme dizziness, severe headache, rapid heart rate, muscle spasms, confusion, or loss of consciousness.

Diet & Lifestyle Advise

  • Follow a strict low-tyramine diet: Avoid foods high in tyramine to prevent a dangerous rise in blood pressure. This includes aged cheeses, sour cream, cured meats (like salami or sausage), draft beers, red wine, soy sauce, tofu, and overripe fruits.
  • Limit caffeine intake: High amounts of caffeine from coffee, tea, energy drinks, or chocolate can interact with Trivon Tablet and cause your blood pressure to rise.
  • Stand up slowly: Trivon Tablet can cause your blood pressure to drop when you stand up, making you feel dizzy. Rise slowly from sitting or lying positions to prevent falls.
  • Keep a food and symptom diary: Track what you eat and how you feel. If you notice a headache or mild dizziness after eating certain foods, note it down and discuss it with your doctor.
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Have a query?

How Soon It Starts Working

The time required for Trivon Tablet to start to work: The time required for Trivon Tablet to show its action is unknown. The time for which the effects of Trivon Tablet last: The duration of action for Trivon Tablet is clinically unknown.

What if you forget to take Trivon Tablet

If you miss a dose of Trivon Tablet , take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and resume your regular schedule. Do not take a double dose to make up for a missed one. Talk to your doctor or pharmacist if you are unsure what to do.

Storage

• Store Trivon Tablet tablets at room temperature, ideally between 20°C and 25°C (68°F to 77°F). • Keep the bottle tightly closed and store it in a dry place away from direct light, heat, and moisture.

Drug Warnings

  • Carry a medical alert card: Always carry an identification card or wear a medical alert bracelet stating that you are taking Trivon Tablet , a monoamine oxidase inhibitor (MAOI), in case of medical emergencies.
  • Check over-the-counter medicines: Never take any new cough, cold, allergy, or pain medicines without checking with your pharmacist, as many contain ingredients that can cause life-threatening interactions.
  • Alert other healthcare providers: Inform any doctor, dentist, or surgeon that you are taking Trivon Tablet before having any medical procedures, dental work, or receiving anesthesia.
  • Monitor your blood pressure: Check your blood pressure regularly at home and keep a log for your doctor, especially when starting the medication or gradually increasing your dose.
  • Wait before switching medicines: Never switch to or from Trivon Tablet without medical supervision. Most antidepressants require a washout period (a waiting period that allows Trivon Tablet to leave your body safely) before starting or stopping Trivon Tablet . In many cases, at least 14 days is required, while medicines such as fluoxetine may require up to 5 weeks before Trivon Tablet can be started safely.

Drug-Drug Interactions

verifiedApollotooltip
  • Other antidepressants (e.g., sertraline, duloxetine, amitriptyline): Taking these medicines alongside Trivon Tablet may increase the risk of serotonin syndrome, a serious condition caused by excessive serotonin levels.
  • Decongestants and stimulants (e.g., pseudoephedrine, phenylephrine, certain ADHD medicines): These medicines may cause a sudden and dangerous increase in blood pressure when used with Trivon Tablet .
  • Pain medicines (e.g., tramadol, meperidine): Combining these with Trivon Tablet may increase the risk of serious nervous system side effects.
  • Migraine medicines (e.g., sumatriptan): Taking these medicines alongside Trivon Tablet may increase the risk of serotonin syndrome.
  • Other opioid medicines (e.g., methadone, fentanyl, tapentadol): These medicines may interact with Trivon Tablet and increase the risk of serious side effects.

Drug-Drug Interactions

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How does the drug interact with Trivon Tablet:
Taking doxylamine with Trivon Tablet can increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
There may be a possibility of interaction between Doxylamine and Trivon Tablet, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination(seeing and hearing things that do not exist), fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Trivon Tablet:
Combining Trivon Tablet with Oxcarbazepine can increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Oxcarbazepine with Trivon Tablet is not recommended, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination(seeing and hearing things that do not exist), fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Trivon Tablet:
Taking Procarbazine with Trivon Tablet can increase the risk of high blood pressure.

How to manage the interaction:
Taking Trivon Tablet with Procarbazine is not recommended, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience severe headache, blurred vision, confusion, seizures, chest pain, nausea or vomiting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, sweating, lightheadedness and fainting. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Trivon Tablet:
Taking Trivon Tablet with Levomilnacipran can increases the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Although there is a of interaction between Levomilnacipran and Trivon Tablet, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination(seeing and hearing things that do not exist), fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Trivon Tablet:
Taking Selegiline with Trivon Tablet can increases the risk of high blood pressure.

How to manage the interaction:
Taking Trivon Tablet with Selegiline can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination (seeing and hearing things that do not exist), fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Trivon Tablet:
Taking Trivon Tablet with Propofol may significantly affect your blood pressure.

How to manage the interaction:
Taking Propofol with Trivon Tablet is not recommended, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience any unusual symptoms. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Trivon Tablet:
Taking Trivon Tablet with bupropion can increase the risk of severe high blood pressure.

How to manage the interaction:
Taking Trivon Tablet with Bupropion can cause an interaction, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience headache, sleep disturbances, tremor (shaking of hands & legs), restlessness, nervousness, anxiety, palpitation, and rapid heartbeat. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Trivon Tablet:
Coadministration of Trivon Tablet with Dopamine can cause severe high blood pressure.

How to manage the interaction:
Taking Dopamine with Trivon Tablet is not recommended, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience severe headache, blurred vision, confusion, seizures, chest pain, nausea or vomiting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, sweating, lightheadedness, and/or fainting. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Trivon Tablet:
Combining Trivon Tablet with Tramadol can increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Trivon Tablet with Tramadol is not recommended, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination(seeing and hearing things that do not exist), fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Trivon Tablet:
Taking Trivon Tablet with atomoxetine can cause severe high blood pressure.

How to manage the interaction:
Taking Atomoxetine with Trivon Tablet is not recommended, but it can be taken if a doctor has advised it. However, if you experience severe headache, blurred vision, confusion, seizures, chest pain, nausea or vomiting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, sweating, lightheadedness, and fainting contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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  • Tyramine-rich foods: Avoid aged, fermented, cured, or spoiled foods while taking Trivon Tablet , as they may cause a sudden and dangerous rise in blood pressure.
  • Alcohol: Avoid alcoholic beverages, especially tap beer, red wine, and liqueurs, as they may increase the risk of high blood pressure, dizziness, and drowsiness.
TRANYLCYPROMINE-10MGTyramine-containing food
Severe

Drug-Food Interactions

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TRANYLCYPROMINE-10MGTyramine-containing food
Severe
Common Foods to Avoid:
Pepperoni, Miso Soup, Natto, Ricotta, Salami, Shoyu, Shrimp, Stilton Cheese, Swiss Cheese, Tamari, Tempeh, Fish, Farm Cheese, Fava Beans, Fermented Seafood, Fermented Tofu, Gorgonzola Cheese, Chicken Liver, Chocolates, Cottage Cheese, Cream Cheese, Dried Sausage, Dry-Type Summer Sausages, Cheddar Cheese, Cashews, Camembert, Beef Liver, American Cheese, Almonds, Avocado

How to manage the interaction:
Consuming high-tyramine-containing foods with Trivon Tablet can raise your blood pressure to dangerous levels. Avoid high-tyramine-containing foods while being treated with Trivon Tablet. However, if you experience severe headaches, confusion, blurred vision, problems with speech or balance, nausea, vomiting, chest pain, and sudden numbness or weakness (especially on one side of the body), such as an abnormal heartbeat, chest tightness, blurred vision, or nausea, consult a doctor.

Habit Forming

Yes

Therapeutic Class

[ANTIDEPRESSANT]

FAQs

Trivon Tablet is used to treat moderate to severe depression. It may also help in treating phobia occurring due to depression.
Trivon Tablet works by inhibiting the breakdown of serotonin and noradrenalin and subsequently enhancing their concentrations in the brain.
Do not stop taking Trivon Tablet on your own. Stopping Trivon Tablet suddenly may cause nausea, vomiting, difficulty sleeping, and sweating. Consult your doctor if you experience any difficulty while taking Trivon Tablet , your doctor may reduce the dose gradually.
If you are suffering from bipolar disorder, you might be on medication for the same. Trivon Tablet should be used with caution along with other psychoactive drugs. Consult your doctor before use.
Trivon Tablet belongs to the group of medications called antidepressants called monoamine oxidase inhibitors used to treat moderate to severe depression. It may also help in treating phobia occurring due to depression. Trivon Tablet contains Tranylcypromine, which works by preventing the breakdown of serotonin and noradrenaline, two neurotransmitters that help regulate mood. It helps restore the normal level of serotonin and noradrenaline, thereby helping treat depression.
The common side effects of Trivon Tablet include drowsiness, dry mouth, stomach pain, chills, blurred vision, hair loss, difficulty urinating, weakness, diarrhoea, numbness, burning, or tingling in the arms or legs, and decreased sexual ability. Most of these side effects gradually resolve over time. However, consult the doctor if any of these side effects persist or worsen.
Trivon Tablet should be used in caution with heart patients. Therefore, please consult the doctor if you have any history of heart disease to prevent adverse events.
You must avoid foods high in tyramine, which include aged cheeses, cured or air-dried meats, yeast extracts, soy sauce, tofu, draft beer, and red wine. Eating these foods can cause a dangerous spike in your blood pressure. Talk to your doctor or a dietitian for a complete list of restricted foods.
No, you should not take over-the-counter cold, cough, or allergy medicines without checking with a professional. Many of these products contain decongestants like pseudoephedrine or phenylephrine, which can interact with Trivon Tablet to cause a life-threatening spike in blood pressure. Talk to your doctor or pharmacist before taking any new medication.
This medication can cause a sudden drop in blood pressure when you change positions, especially when moving from lying down to standing. This is called orthostatic hypotension and can make you feel dizzy or faint. Rising slowly helps your body adjust safely. Talk to your doctor if the dizziness persists.
You should avoid alcohol while taking Trivon Tablet . Many alcoholic beverages, especially draft beers and red wines, contain high levels of tyramine, which can cause severe blood pressure spikes. Additionally, alcohol can increase drowsiness caused by the medication. Talk to your doctor about safe dietary habits.
You must inform your surgeon, anesthesiologist, or dentist that you are taking Trivon Tablet well in advance of any scheduled procedure. Trivon Tablet can interact dangerously with certain anesthetics and pain relievers used during surgery. Your doctor may advise you to temporarily stop taking it before the procedure. Talk to your doctor to plan safely.
No, you cannot switch immediately. You must wait at least 14 days after stopping Trivon Tablet before starting a different antidepressant. This "washout period" is critical to allow Trivon Tablet to leave your system completely and prevent a life-threatening interaction known as serotonin syndrome. Talk to your doctor for a safe switching plan.
The safety of this medication during pregnancy is not fully established, and it is generally not recommended unless the benefits outweigh the potential risks to the developing baby. If you are pregnant, planning to become pregnant, or breastfeeding, you should discuss alternative treatment options with your healthcare provider. Talk to your doctor before making any ch

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Country of origin

India

Manufacturer/Marketer address

Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.
Other Info - TRI1474
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