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  3. Triptamin-Pr Tablet 10'S

Triptamin-Pr Tablet 10'S, Pack of 10
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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy
Triptamin-Pr Tablet is a tricyclic antidepressant used in the prevention of migraine attacks with co-morbid conditions like insomnia, neuralgic pain, hypertension, and anxiety. This combination medicine increases serotonin levels and decreases electrical activity in the brain, thereby helping to relieve your symptoms of pain or migraine. Common side effects include weight gain, dry mouth, blurred vision, increased intraocular pressure, constipation, sedation and drowsiness, hypotension, etc.
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Composition :

AMITRIPTYLINE-10MG + PROPRANOLOL-40MG

Manufacturer/Marketer :

El Dorado Biotech Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Triptamin-Pr Tablet

Triptamin-Pr Tablet belongs to a group of medicines called tricyclic anti-depressants used to prevent migraine attacks with co-morbid conditions like insomnia, neuralgia pain, hypertension, and anxiety. A migraine is usually a moderate or severe headache felt as a throbbing pain on one side of the head.

Triptamin-Pr Tablet is a combination of two medicines, namely, amitriptyline and propranolol. Amitriptyline inhibits the membrane pump mechanism responsible for the serotonin uptake in serotonergic neurons, increasing serotonin levels and decreasing electrical activity in the brain. Amitriptyline can also change how your nerves receive pain signals so the pain goes away. Propranolol is a beta-blocker. It also widens the blood vessels in the body for better blood flow. Thereby, it helps to relieve your symptoms of pain or migraine.

You are advised to take Triptamin-Pr Tablet for as long as your doctor has prescribed it for you, depending on your medical condition and response to the treatment. In some cases, you may experience common side effects such as weight gain, dry mouth, blurred vision, increased intraocular pressure, constipation, sedation and drowsiness, hypotension, syncope, tachycardia, palpitations, myocardial infarction, and arrhythmias. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

To treat your condition effectually, continue using Triptamin-Pr Tablet for as long as your doctor has prescribed it. Do not use Triptamin-Pr Tablet without a doctor's advice if you had a skin reaction or irritation to any medicine. Consult your doctor before using Triptamin-Pr Tablet if you are pregnant or breastfeeding. Do not use Triptamin-Pr Tablet in more than prescribed doses or longer duration as it may cause adverse effects. Keep your doctor informed about your health condition and all the medicines you take before taking Triptamin-Pr Tablet to rule out any side effects.

Uses of Triptamin-Pr Tablet

Prevention of migraine attacks with co-morbid conditions like insomnia, neuralgic pain, hypertension, and anxiety

Directions for Use

• Triptamin-Pr Tablet can be taken with or without food as advised by your doctor.• Follow your doctor's instructions on the dosage and timing of this medication.• Swallow Triptamin-Pr Tablet as a whole with a glass of water.• Do not crush, break, or chew it.

Medicinal Benefits

Triptamin-Pr Tablet prevents migraine attacks with co-morbid conditions like insomnia, neuralgic pain, hypertension, and anxiety. It contains amitriptyline and propranolol. Amitriptyline inhibits the membrane pump mechanism responsible for the serotonin uptake in serotonergic neurons, increasing serotonin levels and decreasing electrical activity in the brain. Amitriptyline can also change how your nerves receive pain signals so the pain goes away. Propranolol is a beta-blocker. It also widens the blood vessels in the body for better blood flow. Thereby, it helps to relieve your symptoms of pain or migraine.

How Triptamin-Pr Tablet Works

Triptamin-Pr Tablet is a combination of two medicines, namely, amitriptyline and propranolol. Amitriptyline inhibits the membrane pump mechanism responsible for the serotonin uptake in serotonergic neurons, increasing serotonin levels and decreasing electrical activity in the brain. Amitriptyline can also change how your nerves receive pain signals so the pain goes away. Propranolol is a beta-blocker. It also widens the blood vessels in the body for better blood flow. Thereby, it helps to relieve your symptoms of pain or migraine.

Storage

• Store in a cool and dry place away from sunlight.• Keep Triptamin-Pr Tablet out of sight and reach of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Triptamin-Pr Tablet
Managing Medication-Triggered Productive cough (wet cough): A Step-by-Step Guide:
  • If you experience a persistent cough after taking medication, consult your doctor to determine the best course of action.
  • Your doctor will assess and adjust your medication regimen if necessary to minimize the cough.
  • Your doctor may recommend cough medications, such as expectorants, to help loosen and clear mucus.
  • Stay hydrated by drinking plenty of fluids, and consider a soothing lifestyle, such as a warm, humid environment, avoiding irritants like smoke and dust, and getting plenty of rest.
  • If your cough persists or worsens, follow up with your doctor for further evaluation and treatment.
Managing Medication-Triggered Anxiety: A Comprehensive Approach:
  • Inform your doctor about your anxiety symptoms so that you doctor may explore potential drug interactions and alter your treatment plan.
  • Work with your doctor to adjust your medication regimen or dosage to minimize anxiety symptoms.
  • Reduce anxiety symptoms by practicing relaxation techniques like meditation, deep breathing, or yoga.
  • Regular self-care activities, such as exercise, healthy food, and adequate sleep, can assist control anxiety.
  • Surround yourself with a supportive network of friends, family, or a support group to help manage anxiety and stay motivated.
  • Regularly track anxiety symptoms and report any changes to your doctor to ensure your treatment plan is effective and adjusted as needed.
Here are the steps to Dry Mouth (xerostomia) caused by medication:
  • Inform your doctor about dry mouth symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Drink plenty of water throughout the day to help keep your mouth moist and alleviate dry mouth symptoms.
  • Chew sugar-free gum or candies to increase saliva production and keep your mouth moisturized.
  • Use saliva substitutes, such as mouthwashes or sprays, only if your doctor advises them to help moisturize your mouth and alleviate dry mouth symptoms.
  • Avoid consuming smoking, alcohol, spicy or acidic foods, and other irritants that may aggravate dry mouth symptoms.
  • Schedule regular dental check-ups to keep track of your oral health and handle any dry mouth issues as they arise.
  • Get enough sleep. Maintain a regular sleep cycle.
  • Eat a healthy diet and exercise regularly.
  • Manage stress with yoga or meditation.
  • Limit alcohol and caffeine.
  • Avoid driving or operating machinery unless you are alert.
  • Keep regular sleeping hours.
  • Don’t consume nicotine, caffeine, or alcohol in the hours leading up to bed.
  • Practice relaxation exercises before bedtime.
  • Regular physical activity can promote deeper and better sleep. However, avoid intense exercise within 2-3 hours of bedtime, as it can disrupt your sleep.
  • If nightmares continue, cognitive behavioral therapy (CBT) may be a helpful treatment option. Your doctor may recommend CBT to address underlying issues and provide coping strategies to manage nightmares.
Managing Low Blood Pressure Triggered by Medication: Expert Advice:
  • If you experience low blood pressure symptoms like dizziness, lightheadedness, or fainting while taking medication, seek immediate medical attention.
  • Make lifestyle modifications and adjust your medication regimen under medical guidance to manage low blood pressure.
  • As your doctor advises, regularly check your blood pressure at home. Record your readings to detect any changes and share them with your doctor.
  • Fluid intake plays a vital role in managing blood pressure by maintaining blood volume, regulating blood pressure, and supporting blood vessel function. Drinking enough fluids helps prevent dehydration, maintain electrolyte balance, and regulate fluid balance.
  • Take regular breaks to sit or lie down if you need to stand for long periods.
  • When lying down, elevate your head with extra pillows to help improve blood flow.
  • Avoid heavy exercise or strenuous activities that can worsen low blood pressure.
  • Wear compression socks as your doctor advises to enhance blood flow, reduce oedema, and control blood pressure.
  • If symptoms persist or worsen, or if you have concerns about your condition, seek medical attention for personalized guidance and care.

What if I have taken an overdose of Triptamin-Pr Tablet

Take Triptamin-Pr Tablet only as prescribed by the doctor. Do not exceed the recommended dose, as it might cause an overdose. If you suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

To treat your condition effectually, continue taking Triptamin-Pr Tablet for as long as your doctor has prescribed. Do not take Triptamin-Pr Tablet if you are pregnant or breastfeeding unless prescribed by the doctor. Triptamin-Pr Tablet causes drowsiness, sleepiness and dizziness, do not drive unless you are alert. Avoid consuming alcohol along with Triptamin-Pr Tablet as it could lead to increased drowsiness and dizziness. Keep your doctor informed about your health condition and medicines to rule out any side effects. Triptamin-Pr Tablet can cause extra side effects if you stop taking it suddenly. Talk to your doctor if you want to stop taking it. Amitriptyline in Triptamin-Pr Tablet may cause decreased sex drive and problems with erections and orgasm. Also, Amitriptyline can change appetite.

Drug-Drug Interactions

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PropranololThioridazine
Critical
AmitriptylinePotassium chloride
Critical

Drug-Drug Interactions

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PropranololThioridazine
Critical
How does the drug interact with Triptamin-Pr Tablet:
Coadministration of thioridazine with Triptamin-Pr Tablet may increase the blood levels of thioridazine and cause an irregular heart rhythm that may be serious.

How to manage the interaction:
Although there is an interaction between Triptamin-Pr Tablet and thioridazine, they can be taken together if prescribed by a doctor. However, if you experience sudden dizziness, lightheadedness, fainting, and shortness of breath contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
AmitriptylinePotassium chloride
Critical
How does the drug interact with Triptamin-Pr Tablet:
The combination of Triptamin-Pr Tablet and Potassium chloride may cause stomach and upper intestinal discomfort. (Only applicable to an oral preparation)

How to manage the interaction:
Although co-administration of Triptamin-Pr Tablet and Potassium chloride is not recommended as it can possibly lead to an interaction, they can be taken if prescribed by a doctor. If you experience severe stomach pain, bloating, sudden dizziness or lightheadedness, nausea, vomiting (in particular with blood), decreased hunger, and black stools while taking these medications, consult a doctor immediately. Do not discontinue any medications without talking to a doctor.
AmitriptylineHalofantrine
Critical
How does the drug interact with Triptamin-Pr Tablet:
Combining Triptamin-Pr Tablet and Halofantrine may increase the risk of irregular heartbeat.

How to manage the interaction:
Although combining Triptamin-Pr Tablet with Halofantrine may result in an interaction, it can be used if a doctor recommends it. If you have any heart problems or electrolyte imbalances, you may be susceptible. If you have sudden dizziness, lightheadedness, fainting, or fast or rapid heartbeats during therapy, get emergency medical help. Do not discontinue any medication without consulting a doctor.
AmitriptylineLinezolid
Critical
How does the drug interact with Triptamin-Pr Tablet:
Taking Linezolid with Triptamin-Pr Tablet can increase the risk of serotonin syndrome (increased serotonin hormone).

How to manage the interaction:
Although using Linezolid and Triptamin-Pr Tablet together may cause an interaction, they can be taken if prescribed by a doctor. Consult a doctor if you have symptoms such as confusion, hallucination, fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Inform a doctor if you have recently taken Triptamin-Pr Tablet. Do not discontinue any medications without consulting a doctor.
AmitriptylineMesoridazine
Critical
How does the drug interact with Triptamin-Pr Tablet:
Coadministration of Triptamin-Pr Tablet and Mesoridazine may increase the risk of irregular heartbeat.

How to manage the interaction:
Although combining Triptamin-Pr Tablet with Mesoridazine may result in an interaction, it can be used if a doctor recommends it. If you have any heart problems or electrolyte imbalances, you may be susceptible. If you have sudden dizziness, lightheadedness, fainting, or fast or rapid heartbeats during therapy, get emergency medical help. Do not discontinue any medication without consulting a doctor.
AmitriptylineDronedarone
Critical
How does the drug interact with Triptamin-Pr Tablet:
Combining Triptamin-Pr Tablet and Dronedarone may increase the risk of irregular heartbeat.

How to manage the interaction:
Although combining Triptamin-Pr Tablet with Dronedarone may result in an interaction, it can be used if a doctor recommends it. If you have any heart problems or electrolyte imbalances, you may be susceptible. If you have sudden dizziness, lightheadedness, fainting, or fast or rapid heartbeats during therapy, get emergency medical help. Do not discontinue any medication without consulting a doctor.
AmitriptylineCisapride
Critical
How does the drug interact with Triptamin-Pr Tablet:
Coadministration of Triptamin-Pr Tablet and Cisapride may increase the risk of irregular heartbeat.

How to manage the interaction:
Although combining Triptamin-Pr Tablet with Cisapride may result in an interaction, it can be used if a doctor recommends it. If you have any heart problems or electrolyte imbalances, you may be susceptible. If you have sudden dizziness, lightheadedness, fainting, or fast or rapid heartbeats during therapy, get emergency medical help. Do not discontinue any medication without consulting a doctor.
AmitriptylineSelegiline
Critical
How does the drug interact with Triptamin-Pr Tablet:
Co-administration of Triptamin-Pr Tablet together with Selegiline can increase the risk of serotonin syndrome (A condition resulting from the accumulation of high levels of serotonin in the body. Serotonin is a mood stabilizer).

How to manage the interaction:
Although using Selegiline and Triptamin-Pr Tablet together may cause an interaction, they can be taken if prescribed by a doctor. Consult a doctor if you have symptoms such as confusion, hallucination, fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Inform a doctor if you have recently taken Triptamin-Pr Tablet. Do not discontinue any medications without consulting a doctor.
AmitriptylinePhenelzine
Critical
How does the drug interact with Triptamin-Pr Tablet:
Using Triptamin-Pr Tablet together with Phenelzine can increase the risk of serotonin syndrome (A condition resulting from the accumulation of high levels of serotonin in the body. Serotonin is especially a mood stabilizer).

How to manage the interaction:
Although using Phenelzine and Triptamin-Pr Tablet together may cause an interaction, they can be taken if prescribed by a doctor. Consult a doctor if you have symptoms such as confusion, hallucination, fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Inform a doctor if you have recently taken Triptamin-Pr Tablet. Do not discontinue any medications without consulting a doctor.
AmitriptylineSafinamide
Critical
How does the drug interact with Triptamin-Pr Tablet:
Using Triptamin-Pr Tablet together with Safinamide can increase the risk of serotonin syndrome (A condition resulting from the accumulation of high levels of serotonin in the body. Serotonin is especially a mood stabilizer).

How to manage the interaction:
Although using Safinamide and Triptamin-Pr Tablet together may cause an interaction, they can be taken if prescribed by a doctor. Consult a doctor if you have symptoms such as confusion, hallucination, fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Inform a doctor if you have recently taken Triptamin-Pr Tablet. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Maintaining a healthy diet and exercising regularly helps improve overall health and boosts self-esteem.
  • Regularly attend therapy sessions.
  • Perform meditation and yoga. This helps in relieving stress and provides relaxation.
  • Follow a regular sleep pattern to improve the amount and quality of sleep you get.
  • Include foods rich in omega fatty acids such as fish, nuts, fresh fruits, vegetables and olive oils.
  • Neurotransmitters are made up of amino acids. Amino acid-rich foods such as meat, dairy products, and certain fruits and vegetables help maintain neurotransmitters.
  • Complex carbohydrates help in stimulating serotonin (a feel-good neurotransmitter). These include whole grains, legumes, spinach, broccoli, oranges and pears.
  • Exercising helps in the production of the body’s natural antidepressants. It also helps relieve stress, improve mood, boost self-esteem, and provide restful sleep.
  • Avoid smoking and alcohol consumption.
  • Learn about your condition, understand the risk factors and follow the doctor’s treatment plan.

Habit Forming

No

Therapeutic Class

ANTIDEPRESSANT

Triptamin-Pr Tablet Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Caution

Avoid consuming alcohol when taking the Triptamin-Pr Tablet as it may cause excessive drowsiness.

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Pregnancy

Caution

There is limited data on how Triptamin-Pr Tablet affects pregnancy. Please consult your doctor if you are planning to become pregnant or are already pregnant before starting Triptamin-Pr Tablet .

bannner image

Breast Feeding

Caution

Consult your doctor; there is no substantial research yet on using Triptamin-Pr Tablet in breastfeeding/nursing mothers.

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Driving

Caution

Triptamin-Pr Tablet causes blurred vision and hypotension. Do not drive or operate machinery unless you are alert.

bannner image

Liver

Caution

Triptamin-Pr Tablet to be taken with caution, especially if you have a history of Liver diseases/conditions. Please consult the doctor; your doctor will weigh the benefits and potential risks before prescribing Triptamin-Pr Tablet .

bannner image

Kidney

Caution

Triptamin-Pr Tablet to be taken with caution, especially if you have a history of Kidney diseases/conditions. Please consult the doctor; your doctor will weigh the benefits and potential risks before prescribing Triptamin-Pr Tablet .

bannner image

Children

Unsafe

The safety and efficacy of Triptamin-Pr Tablet in children have not been established.

Have a query?

FAQs

Triptamin-Pr Tablet belongs to a group of medicines called tricyclic anti-depressants used to prevent migraine attacks with co-morbid conditions like insomnia, neuralgia pain, hypertension, and anxiety.

Triptamin-Pr Tablet contains amitriptyline and propranolol. Amitriptyline inhibits the membrane pump mechanism responsible for the serotonin uptake in serotonergic neurons, increasing serotonin levels and decreasing electrical activity in the brain. Amitriptyline can also change the way that your nerves receive pain signals so the pain goes away. Propranolol is a beta-blocker. It also widens the blood vessels in the body for better blood flow. Thereby, it helps to relieve your symptoms of pain or migraine.

No, it is a prescribed drug given by a physician to prevent specific medical conditions. Taking it on your own can cause unwanted side effects.

Amitriptyline in Triptamin-Pr Tablet may cause decreased sex drive and problems with erection and orgasm. Consult your doctor if you have any concerns regarding this.

Triptamin-Pr Tablet may cause dry mouth as an adverse effect. Limiting caffeine intake, avoiding smoking and alcohol-containing mouthwashes, drinking plenty of water, and eating sugar-free gum/candy may help promote saliva and prevent mouth drying.

There is no indication that Triptamin-Pr Tablet impacts male or female fertility. Consult your doctor if you are trying to conceive or have difficulty conceiving while taking Triptamin-Pr Tablet .

Country of origin

INDIA

Manufacturer/Marketer address

74/01, Sector G.C, CIDCO, Waluj, Aurangabad (MS)
Other Info - TRI1565

Disclaimer

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Veda MaddalaDoctor badge

Reviewed By

Veda Maddala

M Pharmacy

Last Updated

Jul 18, 2025 | 6:58 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.centaurpharma.com/downloads/2021/neurology/Triptolol.pdf
  2. https://www.nhs.uk/medicines/amitriptyline-for-pain/
  3. https://www.drugs.com/drug-interactions/amitriptyline.html
  4. https://www.drugs.com/disease-interactions/propranolol.html#PVD

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