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  3. Trigil-25 mg Tablet 10's

Trigil-25 mg Tablet 10's, Pack of 10
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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Trigil-25 mg Tablet 10's is used to treat epilepsy/seizures/fits. Additionally, it also treats bipolar disorder. It contains Lamotrigine, which reduces the electrical impulses and firing of the nerve impulses that cause fits. In some cases, this medicine may cause side effects such as headache, nausea, vomiting, dry mouth, dizziness, fatigue, abdominal pain, and infection. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Composition :

LAMOTRIGINE-25MG

Manufacturer/Marketer :

Xender Biopharma & Research Llp

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Trigil-25 mg Tablet 10's

Trigil-25 mg Tablet 10's belongs to a group of anticonvulsants or anti-epileptics used to treat epilepsy/seizures/fits. Additionally, Trigil-25 mg Tablet 10's also treats bipolar disorder. Epilepsy is a sudden rush of electricity in the brain. In epilepsy, the brain's electrical rhythms become imbalanced, resulting in recurrent seizures, sometimes leading to an unconscious state. Bipolar disorder is a severe brain disorder in which a person experiences extreme mood swings (variance in thinking) and frequent mood and behavioural changes.

Trigil-25 mg Tablet 10's contains Lamotrigine, which works by blocking sodium channels and reducing the release of glutamate, a brain chemical that can trigger seizures or mood changes. This calms excessive nerve activity, helping control seizures in epilepsy and reducing the risk of mood episodes in bipolar disorder.

You are advised to take Trigil-25 mg Tablet 10's for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side effects such as skin rash, headache, nausea, vomiting, dryness in the mouth, insomnia (difficulty in sleeping), sleepiness, dizziness, back pain, fatigue, abdominal pain, blurred vision, double vision, impaired coordination, nasal congestion (stuffy nose), and infection. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

To treat your condition effectually, do not stop taking Trigil-25 mg Tablet 10's without consulting your doctor to avoid worsening of seizures. Do not take Trigil-25 mg Tablet 10's if you are pregnant or planning for pregnancy unless prescribed by the doctor, as it could lead to serious congenital disabilities. If you are of childbearing age, use effective contraception while taking Trigil-25 mg Tablet 10's. Consult your doctor before taking Trigil-25 mg Tablet 10's if you are breastfeeding. Contact your doctor if your child gets her first period whilst on treatment with Trigil-25 mg Tablet 10's. Do not drive or operate machinery as Trigil-25 mg Tablet 10's causes drowsiness and dizziness. Avoid consuming alcohol along with Trigil-25 mg Tablet 10's as it could lead to increased dizziness and sleepiness. Consult your doctor immediately if you experience suicidal tendencies.

Uses of Trigil-25 mg Tablet 10's

Trigil-25 mg Tablet 10's is used in the treatment of epilepsy (fits) and bipolar disorder. The detailed uses of Trigil-25 mg Tablet 10's are as follows:

  • Epilepsy/seizures: Trigil-25 mg Tablet 10's controls seizures by stabilizing abnormal electrical activity in the brain, reducing their frequency and severity.
  • Bipolar Disorder: Trigil-25 mg Tablet 10's helps prevent mood swings or depressive episodes, maintaining emotional balance in individuals with bipolar disorder.

Directions for Use

  • Trigil-25 mg Tablet 10's can be taken with or without food, as food does not impact its effectiveness or absorption.
  • It is usually taken once or twice a day or as directed by your doctor.
  • Dissolve the prescribed amount of Trigil-25 mg Tablet 10's in a glass of water and consume it immediately.
  • Do not crush, chew, or swallow the tablet as a whole.
  • Do not touch Trigil-25 mg Tablet 10's with wet hands.

Medicinal Benefits

  • Trigil-25 mg Tablet 10's contains Lamotrigine, which helps control seizures by stabilizing abnormal electrical activity in the brain.
  • It reduces the release of glutamate, a chemical messenger that can trigger seizures, preventing excessive nerve overactivity.
  • It decreases the frequency and severity of seizures in conditions such as partial-onset seizures, primary generalized tonic-clonic seizures, and Lennox–Gastaut syndrome.
  • It helps delay the occurrence of mood episodes (depressive, manic, or mixed) in individuals with Bipolar I Disorder, maintaining long-term emotional balance.
  • It has a well-established safety profile in pediatric epilepsy and is not associated with physical or psychological dependence or abuse potential.

How Trigil-25 mg Tablet 10's Works

Trigil-25 mg Tablet 10's contains Lamotrigine, which works by blocking sodium channels and reducing the release of glutamate, a brain chemical that can trigger seizures or mood changes. This calms excessive nerve activity, helping control seizures in epilepsy and reducing the risk of mood episodes in bipolar disorder.

Storage

• Store in a cool and dry place away from sunlight.• Keep Trigil-25 mg Tablet 10's out of the sight and reach of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Trigil-25 mg Tablet
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Wear an eye patch or opaque contact lens or lens applied to glasses to block the vision of one eye to minimize double vision.
  • Use prisms (lenses applied to glasses) to correct double vision due to small misalignments.
  • Try doing some eye exercises such as moving the target towards nose slowly or focussing on a detailed target like thin stick or small text in a magazine.
  • If you feel eye pain, develop bulging eyes, have weakness, headache or double vision, consult a doctor immediately.
  • Uncoordinated muscle movements need immediate medical attention.
  • Observe your movements and try to understand and control the particular movement.
  • Regularly do strengthening exercises to improve blood flow throughout the body and avoid involuntary movements.
  • Implement massage techniques to enhance blood flow to organs.
  • Take a balanced diet and quit smoking.
  • Practice yoga and meditation to improve thought processes and reduce uncontrolled and involuntary movements.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
  • Avoid driving or operating machinery or activities that require high focus until you know how the medication affects you.
  • Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is comfortable to maximize your sleep quality.
  • Limit alcohol and caffeine as these may worsen drowsiness and disturb sleep patterns.
  • Drink plenty of water as it helps with alertness and keeps you hydrated and for overall well-being.
  • Moderate physical activity can improve energy levels, but avoid intense workouts right before bedtime.
Managing Medication-Triggered Rhinitis (Stuffy Nose): A Step-by-Step Guide
  • Consult your doctor if you experience nasal congestion, runny nose, or sinus pressure after taking medication.
  • Your doctor may adjust your treatment plan by changing your medication, adding new medications, or providing guidance on managing your rhinitis symptoms.
  • If advised by your doctor, use nasal decongestants or saline nasal sprays to help relieve nasal congestion.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Stay hydrated by drinking plenty of water and other fluids to help thin out mucus and soothe your nasal passages.

What if I have taken an overdose of Trigil-25 mg Tablet 10's

Take Trigil-25 mg Tablet 10's only as prescribed by the physician. Avoid exceeding the recommended dose as it could lead to an overdose. Symptoms of overdose may include impaired coordination, involuntary eye movement, seizures, decreased level of consciousness, coma, and intraventricular conduction delay (abnormal heart conduction). If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

  • Do not take Trigil-25 mg Tablet 10's if you are allergic to Lamotrigine or its ingredients. Seek immediate medical help if you develop sudden swelling of the face, lips, tongue, or throat, difficulty breathing, or severe skin reactions such as rash, blistering, peeling, or sores in the mouth or around the eyes. These reactions may be life-threatening, especially in children, at high starting doses, or when combined with valproic acid.
  • Inform your doctor about all your existing medical conditions, particularly liver, kidney, or pancreas problems, urea cycle disorders, inflammation of the brain and spinal cord lining, porphyria (a blood pigment disorder), or low platelet levels.
  • Tell your doctor about all medicines, supplements, or herbal products you are taking, as certain drugs may interact with Trigil-25 mg Tablet 10's and increase the risk of side effects.
  • Do not stop taking Trigil-25 mg Tablet 10's suddenly without your doctor’s advice, as abrupt withdrawal can cause serious, life-threatening seizures.
  • Consult your doctor before using Trigil-25 mg Tablet 10's if you are pregnant, planning to become pregnant, or breastfeeding. This medicine may harm the unborn baby and could affect the child’s cognitive abilities (reasoning, intelligence, problem-solving) later in life.
  • Use Trigil-25 mg Tablet 10's with caution in children, as they may have a higher risk of severe skin reactions and other side effects.
  • Avoid alcohol consumption while taking Trigil-25 mg Tablet 10's, as it can increase dizziness, drowsiness, and the risk of side effects.
  • Do not drive or operate heavy machinery until you know how Trigil-25 mg Tablet 10's affects you, as it may cause dizziness, drowsiness, or reduced alertness.

Drug-Drug Interactions

verifiedApollotooltip
LamotrigineDofetilide
Critical
LamotrigineEsketamine
Severe

Drug-Drug Interactions

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LamotrigineDofetilide
Critical
How does the drug interact with Trigil-25 mg Tablet:
Taking Dofetilide with Trigil-25 mg Tablet may significantly increase the blood levels of dofetilide. High blood levels of dofetilide can increase the risk of an irregular heart rhythm that may be serious

How to manage the interaction:
Taking Trigil-25 mg Tablet with Dofetilide is not recommended, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience sudden dizziness, lightheadedness, fainting and shortness of breath. Do not discontinue any medications without consulting a doctor.
LamotrigineEsketamine
Severe
How does the drug interact with Trigil-25 mg Tablet:
Coadministration of Trigil-25 mg Tablet with Esketamine can increase the risk of serious side effects.

How to manage the interaction:
There may be a possibility of interaction between Trigil-25 mg Tablet and Esketamine, but it can be taken if prescribed by a doctor. Consult your doctor immediately if you feel drowsiness, trouble breathing, dizziness, loss of balance, or confusion, it is advised not to drive or use any hazardous machinery. Do not stop taking any medication without consulting your doctor.
LamotrigineSodium oxybate
Severe
How does the drug interact with Trigil-25 mg Tablet:
Taking Trigil-25 mg Tablet with sodium oxybate can increase the risk and severity of side effects.

How to manage the interaction:
Taking Trigil-25 mg Tablet with Sodium oxybate together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience drowsiness, dizziness, lightheadedness, confusion, depression, low blood pressure, slow or shallow breathing, and impairment in thinking, judgment contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
LamotrigineDivalproex
Severe
How does the drug interact with Trigil-25 mg Tablet:
Coadministration of Divalproex and Trigil-25 mg Tablet can increase the risk and severity of side effects.

How to manage the interaction:
Although there is a possible interaction between Divalproex and Trigil-25 mg Tablet, you can take these medicines together if prescribed by your doctor. However, contact your doctor if you experience restlessness, rash, or muscle weakness. Do not stop using any medications without a doctor's advice.
LamotrigineKetamine
Severe
How does the drug interact with Trigil-25 mg Tablet:
Using Ketamine and Trigil-25 mg Tablet together can increase the risk of side effects.

How to manage the interaction:
Although there is a possible interaction between Ketamine and Trigil-25 mg Tablet, you can take these medicines together if prescribed by your doctor. If you feel dizzy, sleepy, confused, have trouble focusing, or have trouble breathing, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
LamotrigineBuprenorphine
Severe
How does the drug interact with Trigil-25 mg Tablet:
When buprenorphine is used with Trigil-25 mg Tablet, it may possibly lead to significant adverse effects such as respiratory difficulties, unconsciousness.

How to manage the interaction:
Concomitant administration of buprenorphine alongside Trigil-25 mg Tablet can result in an interaction, it can be taken if a doctor has advised it. Do not exceed the doses, frequency, or duration of usage advised by a doctor. You should avoid driving or operating hazardous machinery until you're aware of how these medications effect you. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • A ketogenic diet (low in carbohydrates and high in fats) is recommended for children with epilepsy. This diet helps the body utilize fat instead of glucose for energy generation.
  • The Atkins diet (high fat and controlled carbohydrates) is recommended for adolescents and adults.
  • Rest well, and get plenty of sleep.
  • Avoid smoking and alcohol consumption.
  • Exercise, meditation, and yoga can help lower stress, decrease pain sensitivity, and improve coping skills.
  • Prepare your living area; small changes may reduce the risk of physical injury during a seizure.
  • Install an alarm or emergency device to get assistance during a seizure attack.

Habit Forming

No

Therapeutic Class

ANTICONVULSANT

Trigil-25 mg Tablet 10's Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Unsafe

It is advised to avoid alcohol consumption while taking Trigil-25 mg Tablet 10's. Alcohol intake, along with Trigil-25 mg Tablet 10's, may cause increased dizziness and drowsiness. Please consult your doctor for more information.

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Pregnancy

Caution

Trigil-25 mg Tablet 10's is a pregnancy category C drug. Animal studies showed that Trigil-25 mg Tablet 10's affects the fetus in pregnancy, but there is limited data in humans. Using antipsychotic drugs during the third trimester of pregnancy can cause muscle problems in newborns. Please consult your doctor before taking Trigil-25 mg Tablet 10's if you are pregnant or planning to conceive.

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Breast Feeding

Caution

It is not known if Trigil-25 mg Tablet 10's is excreted into the breast milk. Please consult your doctor before taking Trigil-25 mg Tablet 10's if you are a breastfeeding mother.

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Driving

Unsafe

Trigil-25 mg Tablet 10's may make you feel dizzy or drowsy. Do not drive if you are not mentally alert or experience any symptoms that affect your ability to drive or operate machinery.

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Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

bannner image

Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

bannner image

Children

Caution

Trigil-25 mg Tablet 10's can be given to children if prescribed by the doctor. The doctor will adjust the dose.

Have a query?

FAQs

Trigil-25 mg Tablet 10's is used in the treatment of Epilepsy (fits) and Bipolar disorder. It contains Lamotrigine, which reduces the electrical impulses and subsequent firing of the nerve impulses that cause fits. Trigil-25 mg Tablet 10's decreases the brain's excessive and abnormal nerve activity, thereby helping control seizures.

Do not discontinue Trigil-25 mg Tablet 10's without consulting your doctor. To treat your condition effectively, continue taking Trigil-25 mg Tablet 10's for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Trigil-25 mg Tablet 10's. Your doctor will reduce the dose gradually to avoid worsening seizures.

Trigil-25 mg Tablet 10's may cause weight gain due to an increase in appetite. Maintain a healthy weight by following a healthy diet and exercising regularly.

Dry mouth could be a side-effect of Trigil-25 mg Tablet 10's. Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might stimulate saliva and prevent mouth drying.

Trigil-25 mg Tablet 10's helps to treat manic episodes associated with bipolar disorder by increasing the amount of a chemical substance called GABA; this helps in blocking the nerve transmission across the brain and provides a calming effect.

Trigil-25 mg Tablet 10's contains Lamotrigine, which works by blocking sodium channels and reducing the release of glutamate, a brain chemical that can trigger seizures or mood changes. This calms excessive nerve activity, helping control seizures in epilepsy and reducing the risk of mood episodes in bipolar disorder.

Country of origin

India

Manufacturer/Marketer address

2ND FLOOR, SHOP-S/8, SY NO-153/6, SILVER POINT, OPP. VIDHYA BHARTI SCHOOL, BHATAR ROAD, SURAT, Gujarat, India - 395007
Other Info - TRI2243

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Aug 6, 2025 | 11:12 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.drugs.com/mtm/lamotrigine.html#:~:text=Lamotrigine%20is%20an%20anti%2Depileptic,bipolar%20disorder%20(manic%20depression).
  2. https://www.medicines.org.uk/emc/files/pil.6092.pdf

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