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Trigabantin 300 Tablet is a combination medicine used to manage neuropathic pain due to damaged nerves. It helps provide a protective effect on the nerve tissues and the brain. This medicine reduces burning, tingling, numbness, and shooting pain in the hands and feet.

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Written By Veda Maddala , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
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More about the Product

Composition :

ALPHA LIPOIC ACID-100MG+GABAPENTIN-300MG+MECOBALAMIN-0.5MG

Manufacturer/Marketer :

Sun Pharmaceutical Industries Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Trigabantin 300 Tablet

Trigabantin 300 Tablet is a prescription medication primarily used to manage nerve pain, also known as neuropathic pain. It is commonly prescribed to treat discomfort caused by nerve damage due to conditions like diabetes, spinal issues, or shingles. By targeting the root causes of nerve irritation, this medicine helps calm overactive nerve signals in your body.

For the best results, you should take Trigabantin 300 Tablet regularly and consistently at the same times every day as directed by your doctor. You can take this medicine with or without food, depending on what is most comfortable for your stomach. Making simple lifestyle adjustments, such as eating a balanced diet and engaging in light exercise, can also support your nerve health and overall recovery.

While taking Trigabantin 300 Tablet , you may experience some mild, temporary side effects like dizziness or sleepiness as your body adjusts. However, you must consult your doctor immediately if you experience severe symptoms such as difficulty breathing, swelling, or unusual changes in your mood.

Before starting Trigabantin 300 Tablet , tell your doctor if you have any pre-existing health conditions, especially kidney disease, or if you have a history of depression. Do not take this if you are allergic to any of the active components in this medicine.

This medicine can interact with alcohol, which may increase drowsiness, and with certain medications like antacids that reduce how well your body absorbs it. If you are pregnant, breastfeeding, or are an elderly individual, always consult your healthcare provider to ensure this medication is safe for you.

Uses of Trigabantin 300 Tablet

Trigabantin 300 Tablet is used to manage nerve pain. The detailed uses of Trigabantin 300 Tablet are as follows:

  • Diabetic Neuropathy: Helps relieve the burning, tingling, and stabbing nerve pain in the hands and feet caused by chronic high blood sugar levels.
  • Peripheral Neuropathy: Eases nerve discomfort and sensitivity in the extremities caused by general nerve damage or injury.
  • Postherpetic Neuralgia: Relieves the persistent, burning pain that can linger in the nerves after a shingles infection has cleared.

Key Benefits

Trigabantin 300 Tablet offers comprehensive relief by targeting both the symptoms and the underlying health of your nerves. Here are the key benefits you can expect:

  • Effective Pain Relief: It significantly reduces persistent, uncomfortable sensations like burning, freezing, or sharp shooting pains, allowing you to go about your day more comfortably.
  • Improved Daily Mobility: By easing constant discomfort in your feet and hands, this medicine helps restore your ability to walk, move, and perform daily tasks pain-free.
  • Better Sleep Quality: Nerve pain often worsens at night. By calming hyperactive nerves, this medicine helps you sleep more soundly without being interrupted by sudden pain.
Side effects of Trigabantin 300 Tablet
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
  • Get enough sleep. Maintain a regular sleep cycle.
  • Eat a healthy diet and exercise regularly.
  • Manage stress with yoga or meditation.
  • Limit alcohol and caffeine.
  • Avoid driving or operating machinery unless you are alert.

Directions for Use

  • Trigabantin 300 Tablet can be taken with or without food.
  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Swallow the Trigabantin 300 Tablet as a whole with a glass of water.
  • Do not chew, crush, or break it.

How Trigabantin 300 Tablet Works

Trigabantin 300 Tablet works through a combination of three active ingredients that target nerve pain from different angles. Gabapentin (Nerve-Calming Component) calms overactive nerve cells in the body. It works by reducing the release of specific chemical messengers that transmit pain signals through the nervous system to your brain. Mecobalamin (Nerve-Rebuilding Vitamin), an active form of vitamin B12, helps produce myelin, the protective cover that surrounds and shields your nerve fibres. This helps repair damaged nerves and restores proper nerve signalling. Alpha Lipoic Acid (Protective Antioxidant) is a powerful antioxidant that protects nerve cells from damage caused by harmful molecules called free radicals. It also improves blood flow to the nerves, ensuring they receive the vital oxygen and nutrients they need to heal.
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Alcohol

Caution

Avoid consumption of alcohol while taking Trigabantin 300 Tablet as it may increase dizziness and sleepiness.

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Pregnancy

Consult your doctor

Please consult your doctor if you are pregnant before taking Trigabantin 300 Tablet ; your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Consult your doctor

Consult your doctor before taking Trigabantin 300 Tablet if you are breastfeeding; your doctor will decide whether Trigabantin 300 Tablet can be taken by breastfeeding mothers or not.

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Driving

Caution

Trigabantin 300 Tablet causes drowsiness, sleepiness and tiredness. Do not drive or operate machinery unless you are alert after taking Trigabantin 300 Tablet .

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Liver

Consult your doctor

Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Consult your doctor

Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Consult your doctor

Limited information is available regarding the usage of Trigabantin 300 Tablet in children. Please consult a doctor if you have any concerns.

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Heart

Caution

Trigabantin 300 Tablet should be taken with caution in patients with heart problems. Therefore, please inform your doctor before using Trigabantin 300 Tablet .

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Geriatrics

Caution

Trigabantin 300 Tablet should be given with caution to elderly patients due to an increased risk of side effects. Please inform your doctor before use. The doctor may adjust the dose if required.

What if I have taken an overdose of Trigabantin 300 Tablet

If you or someone else takes too much of this medicine, seek immediate medical attention or contact your local emergency services right away. Symptoms of an overdose can include severe dizziness, slurred speech, or deep drowsiness.

Diet & Lifestyle Advise

  • Monitor Blood Sugar: If you have diabetes, keep your blood glucose levels within your target range to prevent further nerve damage.
  • Eat Nerve-Supporting Foods: Include foods high in B vitamins (like green leafy vegetables, eggs, fish, and whole grains) and antioxidants (like berries and spinach) in your daily meals.
  • Stay Active: Engage in regular, low-impact exercise like walking, swimming, or stationary cycling to boost blood flow to your extremities and ease nerve discomfort.
  • Practice Daily Foot Care: Check your feet every day for any cuts, scrapes, red spots, or blisters, as reduced sensation from nerve damage can make it hard to feel small injuries.
  • Avoid Smoking: Quit smoking, as it constricts blood vessels and decreases blood flow to your nerves, which can worsen neuropathic pain.
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Have a query?

How Soon It Starts Working

  • The time required for Trigabantin 300 Tablet to start to work: The time required for Trigabantin 300 Tablet to show its action is unknown.
  • The time for which the effects of Trigabantin 300 Tablet last: The duration of action for Trigabantin 300 Tablet is unknown.

What if you forget to take Trigabantin 300 Tablet

If you miss a dose of Trigabantin 300 Tablet , take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular schedule. Do not take two doses at the same time to make up for a missed one.

Storage

•Keep the medicine in its original packaging to protect it from direct sunlight, moisture, and extreme heat.

Drug Warnings

  • Watch out for sleepiness: Do not drive, ride a bicycle, or operate machinery when you first start taking Trigabantin 300 Tablet , as it can make you feel very dizzy or sleepy.
  • Time your antacids: Avoid taking antacids within 2 hours of taking Trigabantin 300 Tablet , because antacids can make it harder for your body to absorb this medication.
  • Do not stop suddenly: Never stop taking this medicine abruptly. Doing so can cause your nerve pain to return or lead to withdrawal symptoms like anxiety, insomnia, or nausea. Your doctor will help you by gradually decreasing the dose.
  • Monitor your mood: Pay close attention to any sudden or unusual changes in your mood, thoughts, or behaviour, and contact your doctor immediately if you experience feelings of depression.
  • Limit alcohol: Avoid drinking alcohol while taking this medicine, as it can significantly worsen side effects like dizziness and coordination issues.

Drug-Drug Interactions

verifiedApollotooltip
  • Antacids: Taking antacids can lower the absorption of this medicine. Take them at least 2 hours apart.
  • Pain or Sleep Medicines: Combining this medicine with strong pain relievers (like opioids), sleeping pills, or muscle relaxants can cause extreme sleepiness or breathing difficulties.
Gabapentin + Mecobalamin + Thioctic acidHydrocodone
Severe
Gabapentin + Mecobalamin + Thioctic acidBuprenorphine
Severe

Drug-Drug Interactions

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Gabapentin + Mecobalamin + Thioctic acidHydrocodone
Severe
How does the drug interact with Trigabantin 300 Tablet:
When Hydrocodone is taken with Trigabantin 300 Tablet, the amount of Hydrocodone may cause central nervous system depression(a physiological state that can result in a decreased rate of breathing, decreased heart rate).

How to manage the interaction:
Although there is a possible interaction between Trigabantin 300 Tablet and Hydrocodone, you can take these medicines together if prescribed by a doctor. If you notice any symptoms like trouble breathing, dizziness, or trouble focusing, make sure to contact a doctor right away. Do not exceed the doses or frequency and duration of use advised by the doctor. Do not stop using any medications without a doctor's advice.
Gabapentin + Mecobalamin + Thioctic acidBuprenorphine
Severe
How does the drug interact with Trigabantin 300 Tablet:
Co-administration of Buprenorphine and Trigabantin 300 Tablet may cause central nervous system depression(a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although there is a possible interaction between Trigabantin 300 Tablet and Buprenorphine, you can take these medicines together if prescribed by a doctor. However, if you experience any unusual symptoms, consult the doctor immediately. Avoid driving or operating dangerous machinery. Do not exceed the doses or frequency, duration of use advised by the doctor. Do not discontinue any medications without a doctor's advice.
Gabapentin + Mecobalamin + Thioctic acidPethidine
Severe
How does the drug interact with Trigabantin 300 Tablet:
Taking Pethidine with Trigabantin 300 Tablet may cause central nervous system depression(a physiological state that can result in a decreased rate of breathing, decreased heart rate, loss of consciousness).

How to manage the interaction:
Co-administration of Pethidine with Trigabantin 300 Tablet can possibly result in an interaction, but it can be taken if a doctor has advised it. However, if you experience excessive sleepiness, dizziness, difficulty focusing, impaired-judgment, reaction speed and motor coordination, please consult a doctor immediately. Do not exceed the doses or frequency and duration of use advised by the doctor. Do not discontinue any medications without a doctor's advice.
Gabapentin + Mecobalamin + Thioctic acidDezocine
Severe
How does the drug interact with Trigabantin 300 Tablet:
Taking Trigabantin 300 Tablet with Dezocine may cause central nervous system depression(a physiological state that can result in a decreased rate of breathing, decreased heart rate, loss of consciousness).

How to manage the interaction:
Co-administration of Trigabantin 300 Tablet with Dezocine may lead to an interaction, it can be taken if prescribed by the doctor. However, if you experience excessive sleepiness, dizziness, difficulty focusing, impaired-judgment, reaction speed and motor coordination, please consult a doctor immediately. Do not exceed the doses or frequency and duration of use advised by the doctor. Do not discontinue any medications without a doctor's advice.
Gabapentin + Mecobalamin + Thioctic acidTramadol
Severe
How does the drug interact with Trigabantin 300 Tablet:
Co-administration of Tramadol with Trigabantin 300 Tablet may cause central nervous system depression(a physiological state that can result in a decreased rate of breathing, decreased heart rate, loss of consciousness).

How to manage the interaction:
Although there is a possible interaction between Trigabantin 300 Tablet and Tramadol, you can take these medicines together if prescribed by your doctor. However, if you experience excessive sleepiness, dizziness, difficulty focusing, impaired-judgment, reaction speed and motor coordination, please consult a doctor immediately. Do not exceed the doses or frequency and duration of use advised by the doctor. Do not discontinue any medications without a doctor's advice.
Gabapentin + Mecobalamin + Thioctic acidSufentanil
Severe
How does the drug interact with Trigabantin 300 Tablet:
Taking Sufentanil with Trigabantin 300 Tablet may cause central nervous system depression(a physiological state that can result in a decreased rate of breathing, decreased heart rate, loss of consciousness).

How to manage the interaction:
There may be a possibility of interaction between Trigabantin 300 Tablet and Sufentanil, but it can be taken if prescribed by a doctor. However, if you experience excessive sleepiness, dizziness, difficulty focusing, impaired-judgment, reaction speed and motor coordination, please consult a doctor immediately. Do not exceed the doses or frequency and duration of use advised by the doctor. Do not discontinue any medications without a doctor's advice.
Gabapentin + Mecobalamin + Thioctic acidOxycodone
Severe
How does the drug interact with Trigabantin 300 Tablet:
Taking Oxycodone with Trigabantin 300 Tablet may cause central nervous system depression(a physiological state that can result in a decreased rate of breathing, decreased heart rate, loss of consciousness).

How to manage the interaction:
Taking Trigabantin 300 Tablet with Oxycodone together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, if you experience excessive sleepiness, dizziness, difficulty focusing, impaired-judgment, reaction speed and motor coordination, please consult a doctor immediately. Do not exceed the doses or frequency and duration of use advised by the doctor. Do not discontinue any medications without a doctor's advice.
Gabapentin + Mecobalamin + Thioctic acidEsketamine
Severe
How does the drug interact with Trigabantin 300 Tablet:
Taking Trigabantin 300 Tablet with Esketamine can increase the risk of side effects.

How to manage the interaction:
Although taking Trigabantin 300 Tablet and Esketamine together can cause an interaction, it can be taken if a doctor has suggested it. Consult a doctor if you experience any symptoms such as sleepiness, confusion, difficulty concentrating, and impaired-thinking, judgment, reaction speed, and motor coordination. Do not stop using any medications without a doctor's advice.
Gabapentin + Mecobalamin + Thioctic acidCodeine
Severe
How does the drug interact with Trigabantin 300 Tablet:
Using Codeine with Trigabantin 300 Tablet can increase the risk of Central nervous system depression(a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Taking Trigabantin 300 Tablet with Codeine together can possibly result in an interaction, but it can be taken if a doctor has advised it. If you experience dizziness, sleepiness, difficulty concentrating, and impaired-judgment, reaction speed and motor coordination, consult a doctor. Do not exceed the doses or frequency and duration of use prescribed by your doctor. Avoid driving, operating dangerous machinery. Do not stop using any medications without a doctor's advice.
Gabapentin + Mecobalamin + Thioctic acidAlfentanil
Severe
How does the drug interact with Trigabantin 300 Tablet:
Taking Trigabantin 300 Tablet with Alfentanil may cause central nervous system depression(a physiological state that can result in a decreased rate of breathing, decreased heart rate, loss of consciousness).

How to manage the interaction:
Co-administration of Trigabantin 300 Tablet with Alfentanil may lead to an interaction, it can be taken if prescribed by the doctor. However, if you experience excessive sleepiness, dizziness, difficulty focusing, impaired-judgment, reaction speed and motor coordination, please consult a doctor immediately. Do not exceed the doses or frequency and duration of use advised by the doctor. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

verifiedApollotooltip
  • Alcohol: Drinking alcohol while taking this medicine may increase the risk of severe drowsiness, dizziness, and loss of balance.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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FAQs

Trigabantin 300 Tablet is used to treat neuropathic pain.
Trigabantin 300 Tablet contains Gabapentin, Mecobalamin, and Alpha-lipoic acid. Gabapentin modulates the calcium channel activity of the brain cells, thereby decreasing pain. Mecobalamin helps rejuvenate and protect damaged nerve cells by producing a substance called myelin. Alpha-lipoic acid protects the nerve tissues and brain. Together, Trigabantin 300 Tablet helps treat neuropathic pain.
Do not discontinue Trigabantin 300 Tablet without consulting your doctor, as it could lead to withdrawal symptoms. To treat your condition effectively, continue taking Trigabantin 300 Tablet for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Trigabantin 300 Tablet ; your doctor will reduce the dose gradually.
People taking Trigabantin 300 Tablet should be closely monitored for suicidal thoughts or behaviour. Do not be reluctant to speak with your doctor immediately if you experience suicidal tendencies.
Trigabantin 300 Tablet contains gabapentin, which may interfere with laboratory test results. Inform the person doing the tests that you are taking Trigabantin 300 Tablet .
If Trigabantin 300 Tablet is taken along with antacid medicines containing aluminium and magnesium, it may lower the absorption of Trigabantin 300 Tablet from the stomach. To avoid this, maintain a gap of two hours between Trigabantin 300 Tablet and antacid medicines.
Trigabantin 300 Tablet may cause weight gain due to an increase in appetite. Maintain a healthy weight by regular exercise and following a balanced diet.
Both gabapentin and Trigabantin 300 Tablet are used to treat neuropathic pain. However, Trigabantin 300 Tablet contains methylcobalamin and alpha lipoic acid along with gabapentin, which help in nerve regeneration.
It is recommended to take Trigabantin 300 Tablet before food. Try to take it at the same time each day to maintain the consistent levels of Trigabantin 300 Tablet in the body.
The common side effects of Trigabantin 300 Tablet are dizziness, sleepiness, tiredness, nausea and vomiting. If any of these side effects persist or worsen, please consult your doctor.
To manage weight gain, focus on a healthy diet rich in fruits, vegetables, lean proteins, and whole grains. Avoid high-calorie, sugary, and fatty foods. Physical activities like walking, jogging, swimming, or cycling can also help. Be mindful of portion sizes, eat smaller meals, and drink plenty of water. If you notice significant weight gain, consult your doctor for guidance on adjusting your treatment.
Yes, sleepiness or drowsiness may occur in some individuals taking Trigabantin 300 Tablet . If you experience this, be sure to take precautions such as avoiding driving, operating heavy machinery, or engaging in other activities that require mental alertness.
Serious side effects of Trigabantin 300 Tablet include an allergic reaction, suicidal thoughts, anxiety or swelling of limbs (hands, legs or feet). Stop taking Trigabantin 300 Tablet if you experience any signs of these severe side effects. Signs of an allergic reaction include swelling of your face, mouth, lips, gums, tongue and neck. You may even have trouble breathing, skin rash, hives (raised bumps) or blisters. Pay attention to any changes, especially sudden changes, in mood, behaviours, thoughts, or feelings which may be a symptom of suicidal thoughts.
The exact time it takes for Trigabantin 300 Tablet to start working can vary from person to person. Generally, it may take a few days to a few weeks to see the full benefits of Trigabantin 300 Tablet . Therefore, complete the entire course of treatment as prescribed by your doctor. Do not stop taking Trigabantin 300 Tablet early, as symptoms may return or worsen.
No, taking a higher-than-recommended dose may not be more effective; instead, it may increase the risk of serious side effects and toxicity. Therefore, follow your doctor’s instructions and please consult your doctor. If you experience increased severity of your symptoms that are not relieved by the recommended doses, please consult your doctor for re-evaluation.
The frequency of doctor visits can vary depending on your medical condition and treatment plan. Generally, for a medication like Trigabantin 300 Tablet , your doctor may want to see you regularly to monitor your response to the medication and check for any side effects. However, if the recommended doses do not relieve your symptoms or you experience some unwanted side effect that affects your routine activities, consult your doctor.
Store Trigabantin 300 Tablet in a cool and dry place at a temperature not exceeding 25°C, away from sunlight and moisture. Keep out of reach of children.
No, Trigabantin 300 Tablet is not a standard over-the-counter pain reliever like ibuprofen or paracetamol. It is a specialised prescription medication designed specifically to target and calm damaged, overactive nerves. Talk to your doctor if you have questions about how this medicine works for your pain.
It is strongly advised to avoid alcohol while taking Trigabantin 300 Tablet . Alcohol can worsen side effects such as drowsiness, dizziness, and difficulty concentrating. Talk to your doctor or pharmacist if you need advice on managing this.
Take the missed dose as soon as you remember. If your next scheduled dose is only a few hours away, skip the missed dose entirely and resume your regular schedule. Never take a double dose to make up for a missed one. Talk to your doctor or pharmacist if you frequently miss doses.
Yes, antacids can interfere with how your body absorbs Trigabantin 300 Tablet , making it less effective. Ensure you take your antacid at least 2 hours before or 2 hours after taking your medicine. Talk to your pharmacist for help with timing your medications.
Yes, but older adults may be more sensitive to side effects like dizziness, sleepiness, and unsteadiness, which can increase the risk of falls. Doctors often prescribe a lower starting dose for elderly patients. Talk to your doctor about safety measures.

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Country of origin

India

Manufacturer/Marketer address

Sun Pharmaceutical Industries Ltd., SUN HOUSE, CTS No. 201 B/1, Western Express Highway, Goregaon (E), Mumbai 400063
Other Info - TRI0013

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