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  3. Tpsolin 50Mg Inj 2Ml

Tpsolin 50Mg Inj 2Ml, Pack of 1 Injection
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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy
Tpsolin 50Mg Inj 2Ml is an anti-epileptic medication used in the treatment of severe epileptic seizures/fits, to prevent seizures during or after severe head injury and/or neurosurgery. This medicine works by decreasing the abnormal electrical activity in the brain and thus reduces seizures. Common side effects include nausea, vomiting, headache, and constipation.
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Composition :

PHENYTOIN-50MG

Manufacturer/Marketer :

Tamman Titoe Pharma Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Tpsolin 50Mg Inj 2Ml

Tpsolin 50Mg Inj 2Ml belongs to the group of medicines called anti-epileptic agents used to treat severe epileptic seizures/fits (status epilepticus). Also, it is used to prevent seizures during or after severe head injury and/or neurosurgery. Tpsolin 50Mg Inj 2Ml may also be used to treat certain cardiac arrhythmias (irregular heartbeat) caused by certain medicines or in patients who do not respond to conventional anti-arrhythmic medication or cardioversion (a procedure in which low shock is used to restore regular heart rhythm).

Tpsolin 50Mg Inj 2Ml contains 'Phenytoin' that works by decreasing the abnormal electrical activity in the brain. Thereby, Tpsolin 50Mg Inj 2Ml helps prevent and treat epileptic seizures. Tpsolin 50Mg Inj 2Ml treats cardiac arrhythmia by inhibiting rapid inward sodium current and shortening cardiac action potential.

Tpsolin 50Mg Inj 2Ml will be administered by a healthcare professional; do not self-administer. In some cases, Tpsolin 50Mg Inj 2Ml may cause certain common side-effects such as nausea, vomiting, headache, and constipation. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Consult your doctor if you are pregnant or planning for pregnancy. Avoid breastfeeding while on treatment with Tpsolin 50Mg Inj 2Ml. Avoid driving or operating heavy machinery as Tpsolin 50Mg Inj 2Ml may cause drowsiness and dizziness. Avoid consumption of alcohol as it may cause increased dizziness/drowsiness and might affect the concentration of phenytoin in the blood. Inform your doctor about all the medicines you are taking and your health condition to rule out any unpleasant side effects.

Uses of Tpsolin 50Mg Inj 2Ml

Treatment of Epilepsy/Seizures and Cardiac arrhythmia

Directions for Use

• Follow your doctor's instructions on the dosage and timing of this medication to ensure safe and effective use.• Tpsolin 50Mg Inj 2Ml will be administered by the doctor or healthcare professional.• Do not self-administer.

Medicinal Benefits

Tpsolin 50Mg Inj 2Ml belongs to the group of medicines called anti-epileptic agents used to treat severe epileptic seizures/fits (status epilepticus). Also, it is used to prevent seizures during or after severe head injury and/or neurosurgery. Tpsolin 50Mg Inj 2Ml works by decreasing the abnormal electrical activity in the brain. Thereby, Tpsolin 50Mg Inj 2Ml helps prevent and treat epileptic seizures. Tpsolin 50Mg Inj 2Ml may also be used to treat certain cardiac arrhythmias (irregular heartbeat) caused by certain medicines or in patients who do not respond to conventional anti-arrhythmic medication or cardioversion (a procedure in which low shock is used to restore regular heart rhythm). Tpsolin 50Mg Inj 2Ml treats cardiac arrhythmia by inhibiting rapid inward sodium current and shortening cardiac action potential.

How Tpsolin 50Mg Inj 2Ml Works

Tpsolin 50Mg Inj 2Ml contains 'Phenytoin' that works by decreasing the abnormal electrical activity in the brain. Thereby, Tpsolin 50Mg Inj 2Ml helps prevent and treat epileptic seizures. Tpsolin 50Mg Inj 2Ml treats cardiac arrhythmia by inhibiting rapid inward sodium current and shortening cardiac action potential.

Storage

• Store in a cool and dry place away from sunlight.• Keep Tpsolin 50Mg Inj 2Ml out of reach and sight of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Tpsolin 50Mg Inj 2Ml
  • Skin rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.
Here are the few steps for dealing with itching caused by drug use:
  • Report the itching to your doctor immediately; they may need to change your medication or dosage.
  • Use a cool, damp cloth on the itchy area to help soothe and calm the skin, reducing itching and inflammation.
  • Keep your skin hydrated and healthy with gentle, fragrance-free moisturizers.
  • Try not to scratch, as this can worsen the itching and irritate your skin.
  • If your doctor prescribes, you can take oral medications or apply topical creams or ointments to help relieve itching.
  • Track your itching symptoms and follow your doctor's guidance to adjust your treatment plan if needed. If the itching persists, consult your doctor for further advice.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
  • Confusion is a major psychotic disorder that needs immediate medical attention.
  • Acknowledge your experience and put effort to control confusion.
  • Avoid smoking and alcohol intake as it can worsen the condition and increase your confusion.
  • Practice meditation and yoga to avoid anxiety, which can be one of the leading causes.
  • Talk to your dietician and consume food that can improve your mental health.
Here are the steps to manage medication-triggered Nervousness:
  • Tell your doctor immediately if you experience symptoms of Nervousness, such as anxiety, jitteriness, or an increased heart rate, after taking medication or adjusting your medication regimen.
  • Your doctor may adjust your medication regimen to alleviate symptoms of Nervousness. This can include switching to a different medication, reducing the dosage, or temporarily stopping the medication. Your doctor may also recommend alternative techniques like relaxation, mindfulness meditation, or journaling. These techniques can help reduce anxiety and Nervousness.
  • Practice stress-reducing techniques, such as deep breathing exercises, yoga, or journaling, to help manage Nervousness.
  • Engage in regular physical activity, such as walking or jogging, to help reduce anxiety and improve mood.
  • Your doctor may advise considering cognitive-behavioural therapy (CBT) or other forms of talk therapy to address underlying anxiety or Nervousness.
  • You should maintain regular follow-up appointments with your doctor to monitor nervousness symptoms, adjust treatment plans as needed, and discuss any concerns or questions.
Managing Low Blood Pressure Triggered by Medication: Expert Advice:
  • If you experience low blood pressure symptoms like dizziness, lightheadedness, or fainting while taking medication, seek immediate medical attention.
  • Make lifestyle modifications and adjust your medication regimen under medical guidance to manage low blood pressure.
  • As your doctor advises, regularly check your blood pressure at home. Record your readings to detect any changes and share them with your doctor.
  • Fluid intake plays a vital role in managing blood pressure by maintaining blood volume, regulating blood pressure, and supporting blood vessel function. Drinking enough fluids helps prevent dehydration, maintain electrolyte balance, and regulate fluid balance.
  • Take regular breaks to sit or lie down if you need to stand for long periods.
  • When lying down, elevate your head with extra pillows to help improve blood flow.
  • Avoid heavy exercise or strenuous activities that can worsen low blood pressure.
  • Wear compression socks as your doctor advises to enhance blood flow, reduce oedema, and control blood pressure.
  • If symptoms persist or worsen, or if you have concerns about your condition, seek medical attention for personalized guidance and care.
  • Take cold water baths avoiding soap.
  • Avoid scratching and scrubbing to prevent infections while itching.
  • Use nets to prevent insects and mosquitoes.
  • Stop using lotions and creams that cause irritation.
  • Avoid alcohol and caffeine intake.

What if I have taken an overdose of Tpsolin 50Mg Inj 2Ml

Tpsolin 50Mg Inj 2Ml is administered by a health care professional in a hospital setting. Hence, the chances of overdose are less. The neurotoxic effects vary in severity depending on the concentration and can include lethargy, vomiting, ataxia, slurred speech, mild nystagmus, coma, and death. Ironically, phenytoin can cause seizures at very high concentrations. Your doctor may take necessary measures if an overdose is suspected.

Drug Warnings

Do not take Tpsolin 50Mg Inj 2Ml if you are allergic to any of its contents. Inform your doctor if you have decreased heart rate, heart block, low blood pressure, heart failure, diabetes, porphyria (blood disorder), heart rhythm problems, alcohol dependence, kidney or liver problems. Consult your doctor if you are pregnant or planning for pregnancy. Avoid breastfeeding while on treatment with Tpsolin 50Mg Inj 2Ml. Do not drive or operate heavy machinery as Tpsolin 50Mg Inj 2Ml may cause drowsiness and dizziness. Avoid consumption of alcohol as it may cause increased dizziness/drowsiness and might affect the concentration of phenytoin in the blood.

Drug-Drug Interactions

verifiedApollotooltip
PhenytoinVenetoclax
Critical
PhenytoinCimetidine
Critical

Drug-Drug Interactions

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PhenytoinVenetoclax
Critical
How does the drug interact with Tpsolin 50Mg Inj 2Ml:
Using venetoclax together with Tpsolin 50Mg Inj 2Ml may significantly reduce the blood levels of venetoclax leading to decreased effectiveness of venetoclax in treating in your condition.

How to manage the interaction:
Taking Tpsolin 50Mg Inj 2Ml with Venetoclax is not recommended as it can cause an interaction, it can be taken if prescribed by the doctor. Do not stop using any medications without talking to a doctor.
PhenytoinCimetidine
Critical
How does the drug interact with Tpsolin 50Mg Inj 2Ml:
Using Tpsolin 50Mg Inj 2Ml together with cimetidine may increase the effects of Tpsolin 50Mg Inj 2Ml.

How to manage the interaction:
Taking Tpsolin 50Mg Inj 2Ml with Cimetidine is not recommended, it can be taken if prescribed by the doctor. Contact a doctor, if you experience twitching eye movements, slurred speech, loss of balance, tremors, muscle stiffness or weakness, nausea, vomiting, feeling light-headed, fainting, and slow or shallow breathing. Do not stop using any medications without talking to a doctor.
PhenytoinRilpivirine
Critical
How does the drug interact with Tpsolin 50Mg Inj 2Ml:
Using rilpivirine together with Tpsolin 50Mg Inj 2Ml may significantly reduce the blood levels of rilpivirine.

How to manage the interaction:
Taking Rilpivirine with Tpsolin 50Mg Inj 2Ml is not recommended, it can be taken if prescribed by the doctor. Do not stop using any medications without talking to a doctor.
PhenytoinCeritinib
Critical
How does the drug interact with Tpsolin 50Mg Inj 2Ml:
Taking ceritinib with Tpsolin 50Mg Inj 2Ml may significantly reduce the blood levels and effectiveness of Ceritinib.

How to manage the interaction:
Taking Tpsolin 50Mg Inj 2Ml with Ceritinib is not recommended as it can cause an interaction, it can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not stop using any medications without talking to a doctor.
PhenytoinLurasidone
Critical
How does the drug interact with Tpsolin 50Mg Inj 2Ml:
Using lurasidone together with Tpsolin 50Mg Inj 2Ml may significantly decrease the blood levels of lurasidone.

How to manage the interaction:
Using lurasidone with Tpsolin 50Mg Inj 2Ml is not recommended, it can be taken if a doctor has prescribed it. Consult a doctor, if you experience any unusual symptoms. Do not discontinue any medications without consulting a doctor.
PhenytoinRanolazine
Critical
How does the drug interact with Tpsolin 50Mg Inj 2Ml:
Using ranolazine together with Tpsolin 50Mg Inj 2Ml may significantly reduce the blood levels of ranolazine leading to dreceased effectiveness of ranolazine in treating your condition.

How to manage the interaction:
Taking Tpsolin 50Mg Inj 2Ml with Ranolazine is not recommended. They can be taken together if advised by a doctor. However, contact a doctor if you experience any symptoms. Do not stop taking any medications without consulting a doctor.
PhenytoinIsavuconazole
Critical
How does the drug interact with Tpsolin 50Mg Inj 2Ml:
Co-administration of Tpsolin 50Mg Inj 2Ml and Isavuconazole may significantly reduce the blood levels of Isavuconazole, which may make Isavuconazole less effective in treating your condition.

How to manage the interaction:
Taking Isavuconazole with Tpsolin 50Mg Inj 2Ml is not recommended as it can cause an interaction, consult a doctor before taking it. Do not discontinue any medication without consulting a doctor.
PhenytoinPraziquantel
Critical
How does the drug interact with Tpsolin 50Mg Inj 2Ml:
Using praziquantel together with Tpsolin 50Mg Inj 2Ml may significantly reduce the blood levels of praziquantel leading decreased effectiveness.

How to manage the interaction:
Taking Tpsolin 50Mg Inj 2Ml with Praziquantelcan is not recommended as it cause an interaction, it can be taken if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
PhenytoinIbrutinib
Severe
How does the drug interact with Tpsolin 50Mg Inj 2Ml:
Co-administration of Tpsolin 50Mg Inj 2Ml and Ibrutinib may decrease the blood levels of Ibrutinib, which may make ibrutinib less effective.

How to manage the interaction:
Although taking Tpsolin 50Mg Inj 2Ml and Ibrutinib together can result in an interaction, it can be taken if a doctor has prescribed it. Do not discontinue any medications without a doctor's advice.
PhenytoinZinc chloride
Severe
How does the drug interact with Tpsolin 50Mg Inj 2Ml:
Coadministration of Tpsolin 50Mg Inj 2Ml and Zinc chloride can decrease the absorption of Tpsolin 50Mg Inj 2Ml, which can lower its effectiveness.

How to manage the interaction:
Although taking Zinc chloride and Tpsolin 50Mg Inj 2Ml together can cause an interaction, it can be taken if a doctor has suggested it. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • A ketogenic diet (low in carbohydrates and high in fats) is recommended for people with epilepsy. This diet helps in utilizing fat instead of glucose for the generation of energy.
  • Atkins diet (high fat and controlled carbohydrates) is recommended for adolescents and adults.
  • Rest well, and get plenty of sleep.
  • Avoid smoking and alcohol consumption.
  • Exercise, meditation and yoga can help lower stress, decrease pain sensitivity and improve coping skills.
  • Prepare your living area; small changes may reduce the risk of physical injury during a seizure.
  • Install an alarm or emergency device to get assistance during a seizure attack.
  • Have a seizure response plan, this helps those around you know what to do.
  • Understand what triggers seizures and try reducing or avoiding them.
  • Please pay attention to overall health as it can help in reducing seizure activity.

Habit Forming

No

Therapeutic Class

ANTICONVULSANT

Tpsolin 50Mg Inj 2Ml Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Unsafe

You are recommended to avoid alcohol consumption while taking Tpsolin 50Mg Inj 2Ml to prevent unpleasant side-effects. It might also affect the concentration of phenytoin in the blood.

bannner image

Pregnancy

Caution

Consult your doctor if you are pregnant or planning for pregnancy. Your doctor will prescribe Tpsolin 50Mg Inj 2Ml only if the benefits outweigh the risks.

bannner image

Breast Feeding

Unsafe

Avoid breastfeeding while on treatment with Tpsolin 50Mg Inj 2Ml. Please consult your doctor if you have any concerns.

bannner image

Driving

Unsafe

Tpsolin 50Mg Inj 2Ml may cause dizziness and drowsiness. Avoid driving or operating machinery if you experience these symptoms.

bannner image

Liver

Caution

Dose adjustment may be needed. Tpsolin 50Mg Inj 2Ml should be used with caution in patients with liver impairment/liver disease. Please consult your doctor if you have a liver impairment or any concerns regarding this.

bannner image

Kidney

Caution

Dose adjustment may be needed. Tpsolin 50Mg Inj 2Ml should be used with caution in patients with kidney impairment/kidney disease. Please consult your doctor if you have kidney impairment or any concerns regarding this.

bannner image

Children

Safe if prescribed

Tpsolin 50Mg Inj 2Ml can be given to children if prescribed by the doctor.

Have a query?

FAQs

Tpsolin 50Mg Inj 2Ml belongs to the group of medicines called anti-epileptic agents used to treat severe epileptic seizures/fits (status epilepticus), and prevent seizures during or after severe head injury and/or neurosurgery. Tpsolin 50Mg Inj 2Ml may also be used to treat certain cardiac arrhythmias (irregular heartbeat) caused by certain medicines or in patients who do not respond to conventional anti-arrhythmic medication or cardioversion.

Tpsolin 50Mg Inj 2Ml works by controlling overactivity of the brain that causes seizures (fits). Thereby, Tpsolin 50Mg Inj 2Ml helps in controlling epileptic fits.

Tpsolin 50Mg Inj 2Ml can make hormonal contraceptives less effective. Talk to your doctor about using non-hormonal contraceptives like condoms and diaphragm with spermicide to prevent pregnancy.

Tpsolin 50Mg Inj 2Ml may cause hyperglycemia (high blood glucose levels). So, inform your doctor if you have diabetes.

Tpsolin 50Mg Inj 2Ml may affect the metabolism of vitamin D, which could cause osteomalacia. Inform your doctor if you have bone problems.

Tpsolin 50Mg Inj 2Ml might increase blood sugar levels and decrease blood calcium levels, folic acid, phosphate, and vitamin D levels. Inform the person doing the tests that you are taking Tpsolin 50Mg Inj 2Ml.

Country of origin

India

Manufacturer/Marketer address

No-52, Singanna Chetty St, Mount Road, Anna Salai, Chintadripet, Chennai, Tamil Nadu 600002
Other Info - TPS0001

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Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Veda MaddalaDoctor badge

Reviewed By

Veda Maddala

M Pharmacy

Last Updated

Jul 18, 2025 | 7:01 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.medsafe.govt.nz/profs/Datasheet/d/dblphenytoininj.pdf
  2. https://www.hpra.ie/img/uploaded/swedocuments/5e9267db-c89d-4c28-85b9-a71545d596bf.pdf
  3. https://labeling.pfizer.com/ShowLabeling.aspx?id=14822
  4. https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/010151s036lbl.pdf
  5. https://www.drugs.com/mtm/phenytoin-injection.html

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