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  3. Tozuclon AS 20/150 Capsule 10's

Tozuclon AS 20/150 Capsule 10's, Pack of 10 CapsuleS
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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Tozuclon AS 20/150 Capsule is used to prevent myocardial infarction (heart attack), stroke or peripheral vascular disease. It is also used to lower abnormally elevated cholesterol or fat levels (hyperlipidaemia or dyslipidaemia) in the body. It contains Rosuvastatin and Aspirin, which lowers the bad cholesterol (low-density lipoprotein or LDL) levels and increases good cholesterol levels (high-density lipoprotein or HDL) in the blood. Also, it decreases the formation of blood clots by preventing the platelets from clubbing together. It may cause common side effects such as increased bleeding tendency, nausea, abdominal pain, headache, constipation, muscle pain, weakness, dizziness and indigestion. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Composition :

ASPIRIN-150MG + ROSUVASTATIN-20MG

Manufacturer/Marketer :

Carecroft Medic Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Tozuclon AS 20/150 Capsule

Tozuclon AS 20/150 Capsule is used for the prevention of heart attack and stroke. A heart attack generally refers to a blocked flow of blood to the heart due to the blockage of the arteries. The blockage is most often a buildup of fat, cholesterol and other substances, which form a plaque in the arteries that feed the heart (coronary arteries).

Tozuclon AS 20/150 Capsule is composed of rosuvastatin and aspirin. This medicine reduces the bad cholesterol (also known as low-density lipoproteins or LDL), and triglycerides (TG). It also collectively prevents the formation of clots in the blood vessels. Together, Tozuclon AS 20/150 Capsule helps to reduce the risk of heart attack, stroke, and heart-related chest pain (angina).

In some cases, you may experience headache, ankle swelling (oedema), dark urine, muscle weakness, slow heart rate, dizziness, and nausea. Most of these side effects of Tozuclon AS 20/150 Capsule do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Take Tozuclon AS 20/150 Capsule with or without food. Your doctor will advise you on how often you take your medicine based on your medical condition. Try not to stop taking this medicine on your own. Do not chew, break, or crush the medicine.

Avoid taking Tozuclon AS 20/150 Capsule if you are allergic to it. Stopping Tozuclon AS 20/150 Capsule abruptly may worsen your condition and increase your risk of future heart attack. Let your doctor know if you have any active liver disease, bleeding issues, muscle problems, are pregnant or planning to become pregnant or are breastfeeding. Patients should inform the doctor that they are taking Tozuclon AS 20/150 Capsule before any surgery is scheduled or any new medicine is taken.

Uses of Tozuclon AS 20/150 Capsule

Tozuclon AS 20/150 Capsule is used in the prevention of heart attack and stroke. The detailed uses of Tozuclon AS 20/150 Capsule are as follows:

  • Cardiovascular Protection: Tozuclon AS 20/150 Capsule is frequently prescribed to prevent blood clots in individuals at high risk of heart attacks or strokes.
  • Anti-inflammatory Effects: Tozuclon AS 20/150 Capsule is known for its ability to reduce inflammation associated with various medical conditions.
  • Management of Angina: Tozuclon AS 20/150 Capsule supports the management of angina symptoms by enhancing blood flow and reducing the heart's workload.
  • Post-surgical Care: Tozuclon AS 20/150 Capsule is administered after certain surgeries to lower the risk of thromboembolic events, promoting smoother recovery.

Directions for Use

  • Tozuclon AS 20/150 Capsule can be taken with or without food as advised by your doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
  • Swallow Tozuclon AS 20/150 Capsule as a whole with a glass of water.
  • Do not chew, crush or break it.

Medicinal Benefits

  • Tozuclon AS 20/150 Capsule is composed of Rosuvastatin and Aspirin.
  • Rosuvastatin is an antilipemic agent (cholesterol-lowering) which works by blocking liver enzymes, causing the liver to make less cholesterol.
  • It also lowers the bad cholesterol (low-density lipoprotein or LDL) levels and increases good cholesterol levels (high-density lipoprotein or HDL) in the blood.
  • Aspirin is an anti-platelet drug that decreases blood clot's formation by preventing the platelets from clubbing together.
  • Tozuclon AS 20/150 Capsule helps in the free flow of blood, thereby preventing a heart attack, stroke and other peripheral vascular diseases.
  • Tozuclon AS 20/150 Capsule reduces the risk of coronary events, such as heart attack, stroke and angina (chest pain). 

How Tozuclon AS 20/150 Capsule Works

Tozuclon AS 20/150 Capsule is composed of two medicines, namely: Rosuvastatin and Aspirin. Rosuvastatin belongs to the class of antilipemic (cholesterol-lowering) agents. It works by blocking liver enzymes, causing the liver to make less cholesterol. Rosuvastatin lowers the bad cholesterol (low-density lipoprotein or LDL) levels and increases good cholesterol levels (high-density lipoprotein or HDL) in the blood. Aspirin is a non-steroidal anti-inflammatory drug (NSAID) with anti-platelet action. It decreases the formation of blood clots by preventing the platelets from clubbing together. Aspirin acts as a blood-thinning or anti-platelet agent in a low dose (about 75 mg) to prevent heart attack and stroke. Tozuclon AS 20/150 Capsule helps in the free flow of blood, thereby preventing a heart attack, stroke and other peripheral vascular diseases.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of Tozuclon AS 20/150 Capsule

Do not take more than the prescribed dose of Tozuclon AS 20/150 Capsule as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

  • Avoid taking Tozuclon AS 20/150 Capsule if you are allergic to Tozuclon AS 20/150 Capsule or any other components present in it.
  • Before taking Tozuclon AS 20/150 Capsule , let your doctor know if you have a history of liver and kidney diseases or allergic reactions to aspirin and rosuvastatin.
  • If you are at risk of internal bleeding (bleeding inside any tissues, organs or joints of your body), a recent injury/surgery or a planned surgery (including dental) in the next few days, coagulation disorders, and active bleeding issues (peptic ulcer, brain haemorrhage), please inform your doctor before starting the medicine. 
  • The doctor might ask you to stop taking Tozuclon AS 20/150 Capsule a few days before surgery since it can cause an increased risk of bleeding during surgery.
  • If you are pregnant, planning to conceive or breastfeeding, it is essential to seek medical advice before starting Tozuclon AS 20/150 Capsule . 
  • Do not drive or operate machinery if you experience dizziness or drowsiness while using Tozuclon AS 20/150 Capsule . 
  • Please do not consume alcohol since it may worsen the side effects like dizziness and increased blood pressure. 
  • Tozuclon AS 20/150 Capsule is not recommended for use in children under 16 years. 

Drug-Drug Interactions

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AspirinKetorolac tromethamine
Critical
AspirinKetorolac
Critical

Drug-Drug Interactions

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AspirinKetorolac tromethamine
Critical
How does the drug interact with Tozuclon AS 20/150 Capsule:
Combining Ketorolac tromethamine with Tozuclon AS 20/150 Capsule can increase the risk of adverse effects.

How to manage the interaction:
Taking Tozuclon AS 20/150 Capsule with Ketorolac tromethamine is not recommended, as it results in an interaction, it can be taken if advised by a doctor. Do not stop using any medications without a doctor’s advice.
AspirinKetorolac
Critical
How does the drug interact with Tozuclon AS 20/150 Capsule:
Co-administration of Ketorolac and Tozuclon AS 20/150 Capsule may increase the risk of side effects.

How to manage the interaction:
Taking Ketorolac with Tozuclon AS 20/150 Capsule is not recommended but can be taken together if prescribed by a doctor. However, consult a doctor if you experience unusual bleeding or bruising, dizziness, tarry stools, coughing up or vomiting fresh or dried blood, severe headache and weakness. Do not stop using any medications without talking to a doctor.
RosuvastatinDarunavir
Severe
How does the drug interact with Tozuclon AS 20/150 Capsule:
Co-administration of Tozuclon AS 20/150 Capsule and Darunavir can increase the blood levels of Tozuclon AS 20/150 Capsule and can increase the risk of liver damage and rhabdomyolysis(breakdown of skeletal muscle tissue).

How to manage the interaction:
Co-administration of Tozuclon AS 20/150 Capsule and Darunavir can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like muscle pain, tenderness, weakness, dark-colored urine, fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, and yellowing of the skin or eyes, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
RosuvastatinLenalidomide
Severe
How does the drug interact with Tozuclon AS 20/150 Capsule:
Co-administration of Tozuclon AS 20/150 Capsule with lenalidomide may increase the risk of a rare condition called rhabdomyolysis (breakdown of skeletal muscle tissue).

How to manage the interaction:
Although there is an interaction between lenalidomide and Tozuclon AS 20/150 Capsule, it can be taken if prescribed by a doctor. However, if you experience muscle pain, tenderness, or weakness, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.
RosuvastatinCiclosporin
Severe
How does the drug interact with Tozuclon AS 20/150 Capsule:
Co-administration of ciclosporin with Tozuclon AS 20/150 Capsule can increase blood levels of Tozuclon AS 20/150 Capsule. This can increase the risk of developing side effects.

How to manage the interaction:
Co-administration of cyclosporine and Tozuclon AS 20/150 Capsule can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like muscle pain, tenderness, weakness, or dark-colored urine, light colour stools, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
RosuvastatinClopidogrel
Severe
How does the drug interact with Tozuclon AS 20/150 Capsule:
Taking Tozuclon AS 20/150 Capsule with clopidogrel can increase the blood levels of Tozuclon AS 20/150 Capsule. This can increase the risk of side effects.

How to manage the interaction:
Although taking clopidogrel together with Tozuclon AS 20/150 Capsule may result in an interaction, it can be taken if prescribed by your doctor. However, consult your doctor immediately if you experience chills, joint pain or swelling, skin rash, itching, nausea, vomiting, dark-colored urine, and/or yellowing of the skin or eyes. Do not discontinue any medication without consulting your doctor.
RosuvastatinAtazanavir
Severe
How does the drug interact with Tozuclon AS 20/150 Capsule:
Co-administration of Tozuclon AS 20/150 Capsule and Atazanavir can increase the blood levels of Tozuclon AS 20/150 Capsule and can increase the risk of liver damage and rhabdomyolysis( breakdown of skeletal muscle tissue).

How to manage the interaction:
Co-administration of Tozuclon AS 20/150 Capsule and Atazanavir can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like muscle pain, tenderness, weakness, dark-colored urine, fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, and yellowing of the skin or eyes, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
RosuvastatinSimeprevir
Severe
How does the drug interact with Tozuclon AS 20/150 Capsule:
Co-administration of Simeprevir and Tozuclon AS 20/150 Capsule can increase the blood levels of Tozuclon AS 20/150 Capsule and can increase the risk of side effects like liver damage and rhabdomyolysis( breakdown of skeletal muscle tissue).

How to manage the interaction:
Co-administration of Simeprevir and Tozuclon AS 20/150 Capsule can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like muscle pain, tenderness, weakness, dark-colored urine, fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, and yellowing of the skin or eyes, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
RosuvastatinFenofibrate
Severe
How does the drug interact with Tozuclon AS 20/150 Capsule:
Co-administration of Tozuclon AS 20/150 Capsule and Fenofibrate can increase the blood levels of Tozuclon AS 20/150 Capsule and can increase the risk of liver damage and rhabdomyolysis(breakdown of skeletal muscle tissue).

How to manage the interaction:
Co-administration of Tozuclon AS 20/150 Capsule and Fenofibrate can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like muscle pain, tenderness, weakness, dark-colored urine, fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, and yellowing of the skin or eyes, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
RosuvastatinLeflunomide
Severe
How does the drug interact with Tozuclon AS 20/150 Capsule:
Co-administration of leflunomide and Tozuclon AS 20/150 Capsule can increase the risk of developing liver problems.

How to manage the interaction:
Co-administration of Leflunomide and Tozuclon AS 20/150 Capsule can lead to an interaction, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Take the medication as directed by the doctor and at regular intervals. Do not use other over-the-counter medications, herbal or vitamin supplements without informing your pharmacist or doctor when you take Tozuclon AS 20/150 Capsule .
  • A low-cholesterol diet and regular exercise regimen are found to complement treatment with Tozuclon AS 20/150 Capsule effectively.
  • Keep your cholesterol and triglyceride levels under control.
  • Eat at regular intervals and maintain a healthy diet that includes fresh fruits, vegetables.
  • The high-fat meal should be avoided, as it may further increase the risk of a heart attack instead of eating heart-healthy foods.
  • Limit alcohol intake since it raises blood pressure and increases the risk of heart disease.
  • Keep a check on your weight and exercise regularly to keep your heart healthy.
  • Your doctor also guides you on noticing and managing the early symptoms of heart disease. 

Habit Forming

No

Therapeutic Class

CARDIOVASCULAR AGENTS

Tozuclon AS 20/150 Capsule Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Unsafe

It is unsafe to consume alcohol since it may worsen the side effects like dizziness and increase blood pressure.

bannner image

Pregnancy

Unsafe

Tozuclon AS 20/150 Capsule is unsafe to use during pregnancy since it has harmful effects on the foetus. If the patient becomes pregnant while using Tozuclon AS 20/150 Capsule , please discontinue immediately. Please consult your doctor if you are planning to conceive or are already pregnant before starting Tozuclon AS 20/150 Capsule .

bannner image

Breast Feeding

Unsafe

Tozuclon AS 20/150 Capsule is not recommended for use if you are a lactating mother since it may affect the breastfed infant. Please consult your doctor before starting Tozuclon AS 20/150 Capsule .

bannner image

Driving

Unsafe

Do not drive or operate machinery if you experience dizziness or drowsiness while using Tozuclon AS 20/150 Capsule . Tozuclon AS 20/150 Capsule can also sometimes cause blurry vision, hence avoid driving in such situations. Seek medical attention if the symptoms persist longer.

bannner image

Liver

Caution

Let your doctor know if you have any history of liver disease. Your doctor will weigh the benefits and potential risks before prescribing Tozuclon AS 20/150 Capsule .

bannner image

Kidney

Caution

Let your doctor know if you have any history of kidney disease. Your doctor will weigh the benefits and potential risks before prescribing Tozuclon AS 20/150 Capsule .

bannner image

Children

Unsafe

Tozuclon AS 20/150 Capsule is not recommended for children below the age of 16 years. The safety and efficacy of Tozuclon AS 20/150 Capsule have not been established in children.

Have a query?

FAQs

Tozuclon AS 20/150 Capsule is primarily used to prevent myocardial infarction (heart attack), stroke or peripheral vascular disease. It is also used to lower abnormally elevated cholesterol or fat levels (hyperlipidaemia or dyslipidaemia) in the body.

Tozuclon AS 20/150 Capsule consists of Rosuvastatin and Aspirin. Rosuvastatin works by blocking liver enzymes, causing the liver to make less cholesterol. It lowers the bad cholesterol levels and increases good cholesterol levels in the blood, thus preventing heart attack and stroke. Aspirin is a non-steroidal anti-inflammatory (NSAID) and anti-platelet drug that decreases blood clots formation by preventing the platelets from clubbing together, which is the primary cause for heart attack and stroke.

Tozuclon AS 20/150 Capsule consists of Aspirin. It is a blood-thinning agent and can increase the risk of bleeding. It is advised to be cautious during your daily activities like shaving, cutting fingernails or using sharp objects. Also, please consult your doctor beforehand if you undergo any surgery.

Please consult your doctor if Tozuclon AS 20/150 Capsule needs to be discontinued before undergoing a dental procedure or any surgery. The doctor might ask you to stop taking Tozuclon AS 20/150 Capsule a few days before surgery since it can cause an increased risk of bleeding during surgery.

Brief your medical history to your doctor if you have any kidney/liver diseases, asthma, active bleeding issues (like peptic ulcer, brain haemorrhage), gastrointestinal disorders, diabetes, musculoskeletal disorder and mental illness before taking Tozuclon AS 20/150 Capsule .

Tozuclon AS 20/150 Capsule can cause dizziness as one of its side effects. Please consult your doctor if you feel dizzy for a longer time. Avoid driving or operating machinery during episodes of dizziness.

Tozuclon AS 20/150 Capsule is generally safe to take for a long time. It works best if you take it for many months or even years. If you're at risk of getting stomach pain, heartburn or constipation, your doctor may prescribe a medicine to treat such side effects, while you're taking Tozuclon AS 20/150 Capsule .

Take the missed dose as soon as possible. However, if it is time for the next dose, skip the missed dose and go back to your regular dosing schedule.

Swallow the medicine as a whole with water; do not crush, break or chew it. Your doctor will advise you how often you take your tablets based on your medical condition.

Before taking the Tozuclon AS 20/150 Capsule , let your doctor know about all your medical conditions, sensitivities, and all medications you are using. And also inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding.

Low cholesterol diet and regular exercise regime are found to complement treatment with Tozuclon AS 20/150 Capsule effectively.

Yes, in cases, using Tozuclon AS 20/150 Capsule may lead to unexplained muscle pain, tenderness, weakness or cramps. his can happen a few weeks or months after you first start taking this medicine. Contact your doctor if your symptoms continue for more than a few days or get worse.

Adopt a heart-healthy diet, exercise regularly, and avoid smoking and excessive alcohol use to improve drug efficacy and lower cardiovascular risk.

Avoid the use of other painkillers while taking Tozuclon AS 20/150 Capsule . If required, your doctor may suggest paracetamol for relieving pain.

It could be beneficial to take your Tozuclon AS 20/150 Capsule after a meal or snack Keep your meals simple and avoid rich or spicy foods. If your symptoms persist or worsen, see your doctor. Make sure you get enough of rest and drinks.

Tozuclon AS 20/150 Capsule may interact with various medications. Tell your doctor about the medicines you need to take. Your doctor will check the interactions and guide you on how to take them.

Store in a cool and dry place away from sunlight. Keep Tozuclon AS 20/150 Capsule out of sight and reach of children. A medicine take-back program is the best approach to properly dispose of your medicines. To learn about community, take-back initiatives, speak with your pharmacist or contact your local garbage/recycling department.

Tozuclon AS 20/150 Capsule is composed of two medicines, namely: Rosuvastatin (cholesterol-lowering agents) and Aspirin (a non-steroidal anti-inflammatory drug (NSAID) with anti-platelet action).

Country of origin

India

Manufacturer/Marketer address

Common Aristo,Navrachna University Road Bhayli Tp 2, NEAR PRIYA TALKIES, Vadodara-391410, Gujarat, India
Other Info - TOZ0027

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Aug 8, 2025 | 2:05 PM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.centaurpharma.com/downloads/R5A%20and%20R10A.pdf
  2. https://www.ciplamed.com/content/rosulip-asp-capsules
  3. https://www.drugs.com/aspirin.html
  4. https://www.drugs.com/mtm/rosuvastatin.html

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