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compositionComposition:TOPIROXOSTAT-60MG
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Prescription Medicine
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Toxur 60 Tablet treats and manages hyperuricemia (excess uric acid in the blood) and gout. It contains Topiroxostat, which works by inhibiting the enzyme xanthine oxidase (an enzyme essential for the degradation of purine nucleotides to create uric acid), thereby reducing the uric acid level in your body. Thus, it reduces the inflammation caused by uric acid in affected joints, thereby reducing pain, swelling and inflammation.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

TOPIROXOSTAT-60MG

Manufacturer/Marketer :

Blisson Mediplus Pvt Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Toxur 60 Tablet

Toxur 60 Tablet is a prescription medicine used to lower high levels of uric acid in the blood, a condition known as hyperuricemia. By controlling uric acid, it helps prevent painful gout attacks and joint damage over time.

To get the best results, you need to take Toxur 60 Tablet consistently every day, even when you do not have any gout symptoms. You can take this medicine with or without food. Combining this treatment with a low-purine diet and staying well-hydrated will significantly help manage your uric acid levels.

While taking Toxur 60 Tablet , some people may experience mild side effects like joint pain flares, skin rashes, or changes in liver function tests. If you notice severe skin peeling, yellowing of your eyes or skin, or extreme fatigue, you should contact your doctor immediately.

Talk to your doctor before starting this medicine if you have a history of liver disease, kidney problems, or heart conditions. Do not take this if you have had a severe allergic reaction to this medication or any of its ingredients in the past.

Toxur 60 Tablet can interact with certain medicines, especially those that weaken the immune system or treat cancer, potentially causing serious blood disorders. Limit or avoid alcohol while taking this medicine as it can trigger gout attacks, and consult your doctor if you are pregnant, breastfeeding, or planning a pregnancy.

Uses of Toxur 60 Tablet

Toxur 60 Tablet is used to lower high levels of uric acid in the blood and help prevent gout attacks. Your doctor may prescribe it for the following conditions:

  • Hyperuricemia: This medicine lowers high levels of uric acid in the blood to help maintain a healthy balance.
  • Gout management: By keeping uric acid levels low, it prevents the formation of painful crystals in the joints, reducing the frequency of sudden gout attacks.

Key Benefits

Using Toxur 60 Tablet as prescribed helps lower uric acid levels and prevent gout attacks. Here are the key benefits you can expect:

  • Helps prevent gout attacks: Reduces the formation of uric acid crystals, lowering the risk of painful gout flare-ups.
  • Protects joints and kidneys: Helps reduce the risk of long-term damage caused by uric acid crystal deposits.
  • Supports long-term joint health: Maintains healthy uric acid levels, improving mobility and helping you carry out daily activities more comfortably.

Directions for Use

  • Toxur 60 Tablet can be taken with or without food as advised by your doctor.
  • It is recommended to take Toxur 60 Tablet twice daily; however, follow your doctor’s advice regarding the dosage and duration.
  • Swallow the medicine as a whole with a glass of water.
  • Do not break, chew or crush Toxur 60 Tablet .

How Toxur 60 Tablet Works

Toxur 60 Tablet contains topiroxostat, a xanthine oxidase inhibitor that helps lower uric acid levels in the blood. It works by blocking the xanthine oxidase enzyme, which is responsible for producing uric acid in the body. By reducing uric acid production, Toxur 60 Tablet helps prevent the build-up of uric acid and the formation of crystals in the joints, reducing the risk of gout attacks and related complications.
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Alcohol

Consult your doctor

It is not known whether consumption of alcohol is safe while taking Toxur 60 Tablet . Please consult your doctor for more information.

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Pregnancy

Consult your doctor

The safety of Toxur 60 Tablet in pregnant women is unknown. Therefore, please consult your doctor; your doctor will weigh the benefits and potential risks before prescribing this medicine.

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Breast Feeding

Consult your doctor

It is unknown whether Toxur 60 Tablet is excreted in human milk. It should not be used while breastfeeding unless the possible benefits outweigh the risks to the infant. If you are breastfeeding, inform your doctor before using this medicine.

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Driving

Consult your doctor

It is not known whether Toxur 60 Tablet alters the ability to drive. Please consult your doctor if you experience any symptoms that affect your alertness.

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Liver

Consult your doctor

Limited information is available about using Toxur 60 Tablet in patients with liver disease. Inform your doctor before receiving the Toxur 60 Tablet if you have a history of liver diseases. Your doctor will prescribe only if the benefits outweigh the risks.

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Kidney

Consult your doctor

Limited information is available about using Toxur 60 Tablet in patients with kidney disease. Inform your doctor before receiving the Toxur 60 Tablet if you have a history of kidney problems. Your doctor will prescribe only if the benefits outweigh the risks.

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Children

Consult your doctor

Limited information about using Toxur 60 Tablet in children is available, so do not use it without a doctor's advice.

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Heart

Consult your doctor

Please consult your doctor before receiving Toxur 60 Tablet if you have pre-existing heart problems. Your doctor will prescribe Toxur 60 Tablet if the benefits outweigh the risks.

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Geriatrics

Consult your doctor

Please consult a doctor before administering Toxur 60 Tablet to geriatric patients. Your doctor will prescribe Toxur 60 Tablet if the benefits outweigh the risks.

What if I have taken an overdose of Toxur 60 Tablet

If you think you have taken more than the prescribed dose of Toxur 60 Tablet , seek immediate medical attention straight away, even if you do not have any symptoms. Take the medicine pack with you so healthcare professionals know exactly what was taken.

Diet & Lifestyle Advise

  • Stay well hydrated: Drink at least 8–10 glasses of water daily to help your kidneys remove uric acid.
  • Limit high-purine foods: Reduce your intake of red meat, seafood, organ meats, and yeast extracts.
  • Avoid sugary drinks: Limit beverages sweetened with high-fructose corn syrup, as they may increase uric acid levels.
  • Limit alcohol: Avoid or reduce alcohol, especially beer and spirits, as they can trigger gout attacks.
  • Maintain a healthy weight: Aim for gradual weight loss if advised by your doctor, as rapid weight loss may temporarily increase uric acid levels.
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How Soon It Starts Working

The time required for Toxur 60 Tablet to start to work: Toxur 60 Tablet starts to show its action within 1-2 hours of administration. The time for which the effects of Toxur 60 Tablet last: Toxur 60 Tablet effect lasts for approximately 24 hours.

What if you forget to take Toxur 60 Tablet

Take the missed dose as soon as you remember. If it is almost time for your next scheduled dose, skip the missed dose and resume your regular schedule. Do not take a double dose to make up for a missed one.

Storage

• Store Toxur 60 Tablet at room temperature (15°C–30°C), away from direct sunlight, heat, and moisture.

Drug Warnings

  • Expect initial flares: You may experience more gout attacks when you first start taking Toxur 60 Tablet . Do not stop taking your medicine; your doctor may prescribe other treatments to prevent these flares during the first few weeks.
  • Monitor liver health: Your doctor will likely order regular blood tests to check your liver enzymes while you are taking this medicine. Ensure you do not miss these scheduled appointments.
  • Check tablet integrity: Inspect your tablets before taking them; do not use them if the packaging is broken or if the tablets appear discoloured or damaged.
  • Cardiovascular check: Notify your doctor immediately if you have a history of heart disease and experience chest pressure or shortness of breath.
  • Do not share: This medication has been prescribed specifically for your medical condition; never share it with others even if they have similar symptoms.

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  • Mercaptopurine or Azathioprine: Combining Toxur 60 Tablet with these medicines can significantly increase their concentration in your blood, raising the risk of severe blood and bone marrow disorders.

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  • Alcohol: Drinking alcohol while taking this medicine can increase uric acid production and reduce its excretion, making the medication less effective and increasing gout attacks.
     

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[GOUT THERAPY]

FAQs

Toxur 60 Tablet is used to treat and control hyperuricemia (excess uric acid in the blood) and gout. Gout is a chronic condition due to the deposition of uric acid in the joints. It is characterized by intense pain and swelling at the affected joints.
Toxur 60 Tablet contains Topiroxostat, a selective xanthine oxidase inhibitor medicine used to treat and manage hyperuricemia (excess of uric acid in the blood) and gout. It works by inhibiting the enzyme xanthine oxidase (an enzyme essential for the degradation of purine nucleotides to create uric acid), thereby reducing the level of uric acid in your body. Thus, it reduces the inflammation caused by uric acid crystals in affected joints, thereby reducing pain, swelling and inflammation.
This medication is only available with a doctor's prescription. You must use it only if your doctor prescribes it.
It may take several weeks for your uric acid levels to drop or notice a major reduction.
Toxur 60 Tablet helps lower uric acid levels and is used for the long-term management of gout, but it does not permanently cure the condition. Taking the medicine as prescribed, maintaining a healthy weight, limiting alcohol intake, staying well hydrated, and avoiding foods high in purines (such as organ meats and some seafood) can help reduce uric acid levels and lower the risk of future gout attacks. Continue treatment even if your symptoms improve, unless your doctor advises otherwise.
Take Toxur 60 Tablet exactly as prescribed by your doctor. The dose depends on factors such as your medical condition, age, kidney function, and response to treatment. Follow your doctor's instructions regarding the dose and timing, and do not take more than the prescribed amount.
Patients with kidney disease should take Toxur 60 Tablet with caution. Therefore, your doctor may recommend regular monitoring of your kidney function and adjusting the dosage to ensure safety.
When taking Toxur 60 Tablet , it's essential to take it as prescribed by your doctor, drink plenty of fluids to prevent kidney stones and avoid consuming alcohol. Additionally, caution is advised for patients with liver or kidney disease, as well as pregnant or breastfeeding women, and regular monitoring of liver and kidney function is recommended.
The common side effects of Toxur 60 Tablet are liver enzyme elevations, upset stomach, diarrhoea, nausea, drowsiness, headache, and vomiting. Please consult your doctor if any of these side effects persist or worsen.
No, you should not stop taking Toxur 60 Tablet even if you feel better. Stopping the medicine can cause your uric acid levels to rise again, leading to new gout attacks. Talk to your doctor before making any changes.
Yes, if you are already taking Toxur 60 Tablet daily, you should continue taking it during an acute gout attack. However, you should not start taking Toxur 60 Tablet for the very first time during an active, sudden attack unless advised by your doctor. Talk to your doctor about how to manage sudden pain.
It is highly recommended to limit or avoid alcohol, especially beer, while taking Toxur 60 Tablet . Alcohol increases uric acid levels in the body and can trigger gout attacks, which makes the treatment less effective. Talk to your doctor for personalised advice.
In some cases, Toxur 60 Tablet can affect liver enzyme levels, which is why your doctor will monitor your liver function through routine blood tests. If you notice signs like yellowing of your skin or eyes, dark urine, or severe stomach pain, seek medical help immediately. Talk to your doctor for more details.
If you notice a skin rash, itching, or hives while taking Toxur 60 Tablet , stop taking the medicine and contact your doctor immediately. Some skin rashes can be a sign of a serious allergic reaction. Talk to your doctor to determine the cause.
The safety of Toxur 60 Tablet during pregnancy and breastfeeding is not fully established. If you are pregnant, planning a pregnancy, or breastfeeding, you should discuss the risks and benefits with your healthcare provider. Talk to your doctor before starting this medicine.
Generally, yes, Toxur 60 Tablet can be taken alongside pain relievers or anti-inflammatory drugs often prescribed to manage acute gout flares. However, you should always verify that these combinations are safe for your specific health profile. Talk to your doctor or pharmacist before combining medications.
No. Toxur 60 Tablet does not permanently cure gout. It helps lower uric acid levels and prevents future gout attacks when taken regularly as prescribed. Long-term treatment, along with dietary and lifestyle changes, helps control the condition.

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Country of origin

India

Manufacturer/Marketer address

E-311 Eastern Business Dis, Mumbai Suburban Mumbai City Mh 400078 India
Other Info - TOX0050
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