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  3. Topzee-M Cream 15 gm

Topzee-M Cream 15 gm, Pack of 1 CREAM
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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Topzee-M Cream is used to reduce swelling, itching, and redness caused due to certain fungal skin infections. It contains Clobetasol and Miconazole (antifungal), which kills fungi and inhibits the release of certain chemical messengers in the body that cause redness, itching, and swelling. Some people may experience dry skin, itching, irritation, redness, or burning sensation at the site of application. Before using this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Composition :

CLOBETASOL-0.05%W/W + MICONAZOLE-2%W/W

Manufacturer/Marketer :

Atopic laboratories Pvt Ltd

Consume Type :

TOPICAL

Return Policy :

Not Returnable

Expires on or after :

About Topzee-M Cream

Topzee-M Cream is a dermatological combination medication used to reduce swelling, itching, and redness caused due to certain fungal skin infections. Fungal infection is a skin disease in which a fungus attacks the skin tissue and causes infection. Fungal infections may be contagious (spread from one person to another).

Topzee-M Cream contains Clobetasol (corticosteroid) and Miconazole (antifungal). Clobetasol belongs to the class of corticosteroids that work by acting inside skin cells and inhibiting the release of certain chemical messengers in the body that cause redness, itching, and swelling. When the skin reacts to any allergens, such chemicals are released normally. The fungal cell membranes are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents. On the other hand, Miconazole belongs to the class of antifungals that works by causing holes in the fungal cell membranes and killing fungi.

Topzee-M Cream is only for external use. Use Topzee-M Cream as advised by the doctor. Avoid contact of Topzee-M Cream with nose, ears, mouth, or eyes. In case Topzee-M Cream comes in contact with these areas accidentally, rinse with water thoroughly. Some people may experience dry skin, itching, irritation, redness, or burning sensation at the site of application. Most of these side effects of Topzee-M Cream do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are known to be allergic to Topzee-M Cream or any other medicines, please tell your doctor. If you are pregnant or a nursing mother, it is advised to consult a doctor before using Topzee-M Cream. Do not use Topzee-M Cream in more than prescribed doses, or for a prolonged time as it may cause adverse effects. Do not wrap or cover the treated area with bandages unless advised by your doctor.  Avoid using Topzee-M Cream for more than 5 days in children and on the face. Do not apply Topzee-M Cream to broken skin or cuts. Do not swallow Topzee-M Cream. In case of accidental swallowing, contact a nearby poison control centre or consult a doctor immediately. Avoid smoking or going near naked flames as Topzee-M Cream catches fire and burns easily. If you have glaucoma, cataracts, diabetes, psoriasis, adrenal gland, or liver problems, inform your doctor before taking Topzee-M Cream.

Uses of Topzee-M Cream

Treatment of Skin infections

Directions for Use

• Apply Topzee-M Cream twice daily; however, follow your doctor’s advice regarding the dosage and duration.• Take a small amount of the medicine and gently apply it as a thin layer on the affected area of the skin as prescribed by your doctor.• Avoid contact of Topzee-M Cream with nose, mouth or eyes. In case Topzee-M Cream comes in contact with these areas accidentally, rinse with water thoroughly. Wash your hands before and after using Topzee-M Cream if your hands are not the affected area to prevent the spread of infection.

Medicinal Benefits

Topzee-M Cream is a combination of two drugs, namely Clobetasol and Miconazole. Topzee-M Cream is used to reduce swelling, itching, and redness caused due to fungal skin infections. Clobetasol is a corticosteroid that acts inside skin cells and inhibits the release of certain chemical messengers in the body that cause redness, itching, and swelling. When the skin reacts to any allergens, such chemicals are released normally. The fungal cell membranes are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents. Miconazole is an antifungal that causes holes in the fungal cell membranes and kills fungi. Thereby, clears fungal infections and provides relief from cracking, burning, scaling, and itching of the skin caused due to infections.

How Topzee-M Cream Works

Topzee-M Cream contains Clobetasol (corticosteroid) and Miconazole (antifungal). Clobetasol belongs to the class of corticosteroids that work by acting inside skin cells and inhibiting the release of certain chemical messengers in the body that cause redness, itching, and swelling. When the skin reacts to any allergens, such chemicals are released normally. The fungal cell membranes are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents. On the other hand, Miconazole belongs to the class of antifungals that works by causing holes in the fungal cell membranes and killing fungi.

Storage

Keep Topzee-M Cream out of the sight and reach of children.
Side effects of Topzee-M Cream 15 gm
  • Keep your skin clean by gently washing your face two times daily and after sweating. Choose a mild and non-abrasive cleanser.
  • Use gentle alcohol-free skin care products. Avoid products that might irritate your skin such as exfoliants, astringents and toners.
  • Acne may also occur due to oil in the hair. Thus, if you have oily hair, shampoo more frequently than you do now and keep your hair away from face.
  • Keep your hands off your face as touching face throughout the day might worsen acne. Also, do not pick, squeeze or pop acne as it will prolong the healing process and increase the risk of dark spots and scarring.
  • Avoid tanning by applying a broad spectrum sunscreen and wearing sun-protective clothing when outdoors.
  • Mild hair follicle inflammation often heals on its own without needing treatment.
  • You can apply a warm saltwater or vinegar solution to the affected area with a washcloth, or use over-the-counter antibiotics, oatmeal lotion, or hydrocortisone cream for relief.
  • Avoid making the affected area worse by not shaving, scratching, or wearing tight clothes.
  • Apply a warm compress to the area 3-4 times a day for 15-20 minutes to help speed up healing.
  • Do not scratch, squeeze, or pop any bumps, as this may lead to infection or other problems.
  • If self-care methods fail, consult a doctor for further treatment and advice.
  • Shield your skin from the sun by using sunscreen, seeking shade, and wearing protective clothing.
  • Please don't smoke, as it damages the skin and reduces blood flow.
  • Treat your skin gently by limiting bath time, using mild cleansers, and shaving carefully.
  • Eat a healthy diet of fruits, vegetables, whole grains, and lean proteins.
  • Stay hydrated by drinking plenty of water.
  • Manage stress through sleep, exercise, meditation, and enjoyable activities.
  • Additionally, use moisturizers to coat your skin with a protective barrier, and consider wearing sun-protective clothing.
  • Apply moisturizer immediately after showering or bathing.
  • Use a moisturizer containing lanolin, petroleum jelly, glycerine, hyaluronic acid or jojoba oil.
  • Do not use hot water for bathing. Instead use warm water and limit showers and bath to 5 to 10 minutes.
  • Apply a sunscreen with SPF-30 or higher.
  • Avoid harsh soaps, detergents and perfumes.
  • Do not scratch or rub the skin.
  • Drink adequate water to prevent dehydration.
  • Wear pants, full sleeves and a wide-brimmed hat while going out in the sun.

What if I have taken an overdose of Topzee-M Cream

Do not apply Topzee-M Cream in large amounts or use it for a long time than recommended, as it does not give quick or better results but increases the risk of side effects.

Drug Warnings

Avoid contact of Topzee-M Cream with nose, mouth, or eyes as it may irritate. In case Topzee-M Cream comes in contact with these areas accidentally, rinse with water thoroughly. If you are pregnant or a nursing mother, it is advised to consult a doctor before using Topzee-M Cream. If you are allergic to Topzee-M Cream or any other medicines, please tell your doctor. Do not apply Topzee-M Cream to broken skin or cuts. Do not swallow Topzee-M Cream. In case of accidental swallowing, contact a nearby poison control center or consult a doctor immediately. Avoid smoking or going near naked flames as Topzee-M Cream catches fire and burns easily. If you have glaucoma, cataracts, diabetes, psoriasis, adrenal gland, or liver problems, inform your doctor before taking Topzee-M Cream. Topzee-M Cream is not recommended for use in neonates and infants (up to 2 years) as absorption by immature skin may be enhanced, and kidneys may be immature, leading to toxicity.

Drug-Drug Interactions

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Drug-Food Interactions

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Diet & Lifestyle Advise

  • Regularly change your socks and wash your feet. Avoid shoes that make your feet sweaty and hot.
  • In wet places such as changing rooms and gym showers, don’t walk on barefoot to prevent fungal infections.
  • Do not scratch the affected area of skin as it can spread the infection to other body parts.
  • Avoid sharing towels, combs, bedsheets, shoes or socks with others.
  • Wash your bed sheets and towels regularly.

Habit Forming

No

Therapeutic Class

ANTIFUNGALS - TOPICAL

Topzee-M Cream Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Caution

Interaction of Topzee-M Cream with alcohol is unknown. Please consult a doctor before consuming alcohol while using Topzee-M Cream.

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Pregnancy

Caution

Topzee-M Cream is Category C pregnancy drug and is given to a pregnant woman only if the doctor thinks benefits outweigh risks.

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Breast Feeding

Caution

It is unknown whether Topzee-M Cream is excreted in human milk. Please consult a doctor before using Topzee-M Cream while breastfeeding.

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Driving

Safe if prescribed

Topzee-M Cream usually does not affect your ability to drive or operate machinery.

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Liver

Caution

If you have any concerns regarding the use of Topzee-M Cream in patients with Liver problems, please consult a doctor.

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Kidney

Caution

If you have any concerns regarding the use of Topzee-M Cream in patients with Kidney problems, please consult a doctor.

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Children

Caution

Topzee-M Cream should be used with caution in children below 12 years if prescribed by a doctor. Topzee-M Cream is not recommended for use in children below 2 years as in neonates and infants, absorption of Topzee-M Cream by immature skin may be enhanced and kidney may be immature.

Have a query?

FAQs

Topzee-M Cream is used to reduce swelling, itching, and redness caused by certain fungal skin infections.

No, Topzee-M Cream is not recommended to treat acne as it may worsen the condition. Topzee-M Cream is only used to reduce itching, swelling and redness caused due to certain skin infections. However, please consult a doctor before using Topzee-M Cream.

You are recommended to use Topzee-M Cream on the face only if advised by your doctor and do not use for more than 5 days on the face as the skin on face thins easily. Avoid the use of dressing or bandages on the face.

Topzee-M Cream should be used with caution in children if prescribed by a doctor as Topzee-M Cream contains a steroid and may increase the risk of Cushing’s syndrome, HPA axis suppression (suppression of inflammatory and immune responses), adrenal insufficiency, delayed growth and weight gain. However, please consult a doctor before using Topzee-M Cream in children.

You are recommended to use Topzee-M Cream for as long as your doctor has prescribed it. However, if the condition does not improve after 2 to 4 weeks of treatment with Topzee-M Cream, please consult a doctor.

Yes, Topzee-M Cream may increase blood sugar levels. Therefore, inform your doctor if you have diabetes before taking Topzee-M Cream and regularly monitor blood sugar levels while using Topzee-M Cream.

Yes, fungal infection is a contagious skin condition which spreads from one person to another through direct skin to skin contact or by contact with contaminated soil or surfaces and infected animals. Therefore, it is recommended to avoid close direct contact until the infection is clear and avoid sharing things with the infected person as it can also spread the infection.

No, you are not recommended to stop using Topzee-M Cream without consulting your doctor as it may worsen the condition or cause recurring infection. Therefore, take Topzee-M Cream for as long as your doctor has prescribed it and if you experience any difficulty while taking Topzee-M Cream, please consult your doctor.

Topzee-M Cream contains Clobetasol (a corticosteroid) and Miconazole (an antifungal). Clobetasol works by inhibiting the release of certain chemical messengers in the body that cause redness, itching, and swelling. These chemicals are normally released when the skin reacts to allergens. On the other hand, Miconazole works by damaging fungal cell membranes, effectively killing the fungi.

The common side effects of Topzee-M Cream include dry skin, itching, irritation, redness, and a burning sensation at the site of application. Most of these side effects do not require medical attention and will gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Do not use Topzee-M Cream in more than the prescribed doses or for a prolonged period, as this may cause adverse effects. Avoid wrapping or covering the treated area with bandages unless advised by your doctor. Do not apply Topzee-M Cream to broken skin or cuts. Do not swallow Topzee-M Cream; in case of accidental swallowing, contact a nearby poison control centre or consult your doctor immediately. Avoid smoking or going near open flames, as Topzee-M Cream is flammable and burns easily. Avoid contact with eyes or mucous membranes; in case of accidental contact, rinse with water immediately.

No, do not stop using Topzee-M Cream without consulting your doctor. To treat your condition effectively and prevent a recurrence of infection, continue using Topzee-M Cream for the prescribed duration.

Using Topzee-M Cream for a long time or at a higher than the recommended dose can make your skin thinner or cause stretch marks. The medicine may get absorbed into the bloodstream and can lead to serious side effects, such as adrenal gland problems, hyperglycemia (high blood sugar), or problems with your eyesight. If you experience an increase in the severity of your symptoms, please consult your doctor.

Store Topzee-M Cream in a cool, dry place away from sunlight. Keep it out of reach of children.

Topzee-M Cream is contraindicated in patients with a known allergy to any of its components. If you are pregnant or a nursing mother, please consult a doctor before using Topzee-M Cream. It is not recommended for use in neonates and infants (up to 2 years) because absorption by immature skin may be enhanced, and their kidneys may be immature, leading to potential toxicity.

Country of origin

India

Manufacturer/Marketer address

Building Zone-B No-6, Aagaman, Vallabhavadi,Near Westend Hotel, Gujarat Collage, Ellisbridge, Ahmedabad – 380006. Gujarat,INDIA
Other Info - TOP0467

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Author Details

Veda MaddalaDoctor badge

Written By

Veda Maddala

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 18, 2025 | 6:35 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.drugs.com/clobetasol-topical.html
  2. https://www.drugs.com/mtm/miconazole-topical.html
  3. https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/021535Orig1s003,%20021644Orig1s003lbl.pdf
  4. https://www.nhs.uk/medicines/clobetasol/

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