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compositionComposition:ATORVASTATIN-10MG+NICOTINIC ACID-375MG
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Prescription Medicine
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Tonact Plus Tablet is used to treat high cholesterol. It contains atorvastatin and nicotinic acid which works by reducing the bad cholesterol, triglycerides and increasing the levels of good cholesterol. In some cases, this medicine may cause side effects such as constipation, nausea, stomach pain, weakness, muscle pain, headache, dizziness, and itching. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

ATORVASTATIN-10MG+NICOTINIC ACID-375MG

Manufacturer/Marketer :

Lupin Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Tonact Plus Tablet

Tonact Plus Tablet is a combination oral prescription medication used to manage abnormal cholesterol and lipid levels in the blood. It helps reduce high levels of 'bad' cholesterol (LDL) and fats (triglycerides) while raising 'good' cholesterol (HDL) to lower the risk of heart disease and stroke.

To get the best results, you must take Tonact Plus Tablet consistently every day, exactly as prescribed by your doctor. It is typically taken once daily, and taking it with a low-fat meal or snack at bedtime can help reduce some common side effects like flushing. Along with this medicine, following a heart-healthy diet and staying physically active are essential steps to achieve your target cholesterol levels.

While taking Tonact Plus Tablet , some people may experience mild side effects like warmth or redness on the skin (flushing), itching, or mild stomach upset. However, you should contact your doctor immediately if you experience severe muscle pain, tenderness, weakness, or yellowing of your eyes or skin, as these can be signs of more serious complications.

Talk to your doctor before starting Tonact Plus Tablet if you have a history of liver disease, kidney problems, active peptic ulcers, or severe gout. Do not take this if you are currently suffering from active liver damage, unexplained high liver enzymes, or active bleeding.

This medicine can interact with other prescription drugs, alcohol, and heavy smoking, which may increase the risk of liver damage or muscle issues. If you are pregnant, planning to become pregnant, breastfeeding, or an older adult, consult your doctor or pharmacist, as this medication is not recommended during pregnancy or breastfeeding.

Uses of Tonact Plus Tablet

Tonact Plus Tablet is used to manage abnormal cholesterol and lipid levels in the blood. The detailed uses of Tonact Plus Tablet are as follows:

  • High cholesterol (hypercholesterolaemia): Tonact Plus Tablet helps lower high levels of low-density lipoprotein (LDL) cholesterol, preventing plaque build-up in the blood vessels.
  • High triglycerides (hypertriglyceridemia): Tonact Plus Tablet reduces excessive levels of triglycerides, a type of fat in the blood that can contribute to heart disease.
  • Low high-density lipoprotein (HDL) levels: Tonact Plus Tablet helps increase 'good' cholesterol levels, which assists in clearing harmful cholesterol from the bloodstream.
  • Prevention of cardiovascular events: By managing lipid levels, Tonact Plus Tablet reduces the overall risk of heart attacks, strokes, and other blood vessel complications in high-risk patients.

Key Benefits

Tonact Plus Tablet helps improve your cholesterol profile by targeting multiple blood lipids in a single treatment. By lowering harmful cholesterol and supporting healthy blood vessel function, it helps reduce the risk of long-term cardiovascular complications.

  • Improves Overall Lipid Control: By acting on multiple lipid parameters, Tonact Plus Tablet helps lower harmful cholesterol and triglyceride levels while supporting a healthier cholesterol balance.
  • Supports Long-Term Heart Health: Regular use helps slow the build-up of fatty deposits in the arteries, promoting healthy blood flow and reducing the risk of cardiovascular diseases.
  • Simplifies Cholesterol Management: By combining multiple lipid-lowering medicines in a single formulation, Tonact Plus Tablet reduces the need for separate medications, making it easier to follow your prescribed treatment plan.

Directions for Use

  • Take Tonact Plus Tablet with or without food as advised by your doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Swallow it as a whole with a glass of water.
  • Do not crush, chew or break it.

How Tonact Plus Tablet Works

Tonact Plus Tablet contains two active ingredients that work in different, complementary ways to regulate your body's fat and cholesterol levels. The first active component, atorvastatin, blocks a specific enzyme in the liver that is responsible for producing cholesterol. By reducing this internal production, the liver is forced to pull existing 'bad' cholesterol out of your blood, significantly lowering your overall circulating cholesterol levels. The second active component, nicotinic acid, works by slowing down the liver's production of certain fats and proteins that transport cholesterol. This action effectively reduces triglycerides and very-low-density lipoproteins (VLDL) while simultaneously preventing the breakdown of 'good' (HDL) cholesterol, allowing it to stay in your blood longer to clear out excess fats.
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Alcohol

Unsafe

Do not drink too much while taking this medicine. Drinking a lot of alcohol, you may be more likely to get muscle and liver side effects.

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Pregnancy

Unsafe

Tonact Plus Tablet is not recommended during pregnancy. Contact your doctor before taking Tonact Plus Tablet .

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Breast Feeding

Unsafe

Breastfeeding is not recommended. Contact your doctor before taking Tonact Plus Tablet .

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Driving

Unsafe

Tonact Plus Tablet has negligible influence on the ability to drive and use machines.

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Liver

Caution

Tonact Plus Tablet to be taken with caution, especially if you have a history of Liver diseases/conditions. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Tonact Plus Tablet to be taken with caution, especially if you have a history of Kidney diseases/conditions. The dose may have to be adjusted by your doctor.

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Children

Unsafe

Tonact Plus Tablet is not indicated in the treatment of patients below the age of 10 years.

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Heart

Caution

Please inform your doctor if you have a history of heart disease before using Tonact Plus Tablet . Your doctor will prescribe it only if the benefits outweigh the risks.

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Geriatrics

Caution

Tonact Plus Tablet should be given with caution in elderly patients due to an increased risk of side effects. Seek medical advice if you have any concerns.

What if I have taken an overdose of Tonact Plus Tablet

In case of an accidental overdose, seek immediate medical attention. Symptoms of an overdose may include severe flushing, dizziness, rapid heartbeat, or severe stomach discomfort.

Diet & Lifestyle Advise

  • Adopt a heart-healthy diet: Focus on soluble fibres (such as oats, beans, and lentils) and healthy unsaturated fats (like olive oil and nuts). Avoid trans fats and limit saturated fats from fatty meats and full-fat dairy.
  • Manage niacin-induced flushing: If you experience flushing, ask your doctor if taking a low-dose plain aspirin (if safe for you) 30 minutes before your dose can help prevent this reaction. Avoid hot drinks, alcohol, and spicy foods close to your dosing time.
  • Engage in regular exercise: Aim for at least 150 minutes of moderate-intensity aerobic exercise, like brisk walking or swimming, each week to help boost your 'good' cholesterol.
  • Limit alcohol consumption: Drinking alcohol can increase your risk of liver damage and worsen skin flushing while taking this medicine.
  • Avoid grapefruit products: Grapefruit and grapefruit juice can significantly increase the levels of this medicine in your blood, raising the risk of serious side effects.
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How Soon It Starts Working

The time required for Tonact Plus Tablet to start to work: The time required for Tonact Plus Tablet to show its action is unknown. The time for which the effects of Tonact Plus Tablet last: The duration of action for Tonact Plus Tablet is clinically unknown.

What if you forget to take Tonact Plus Tablet

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and return to your regular schedule. Do not take two doses at the same time to make up for a missed one.

Storage

•Store Tonact Plus Tablet tablets at controlled room temperature, between 20°C and 25°C (68°F to 77°F). •Keep the medication in its original container to protect it from moisture and direct light.

Drug Warnings

  • Always inform any healthcare provider you visit, including dentists and surgeons, that you are taking Tonact Plus Tablet , as it may need to be temporarily paused before certain procedures.
  • Have your liver function checked regularly through blood tests as recommended by your doctor to monitor for early signs of liver damage.
  • Report any unexplained muscle pain or weakness immediately, particularly if you also feel tired or have a fever.
  • Avoid taking over-the-counter niacin supplements while taking Tonact Plus Tablet , as this can lead to an accidental overdose of that active component.
  • If you are taking bile acid-binding resins (another type of cholesterol medicine), take Tonact Plus Tablet either 4 hours before or 4 hours after taking those medications to ensure proper absorption.

Drug-Drug Interactions

verifiedApollotooltip
  • Certain antibiotics and antifungals: May significantly increase the level of this medicine in your body, raising the risk of severe muscle breakdown.
  • Other lipid-lowering drugs (like gemfibrozil or fenofibrate): Can increase the risk of muscle toxicity and kidney problems.
  • Blood thinners: Taking Tonact Plus Tablet may slightly alter how your blood clots, requiring closer monitoring of your bleeding times.
  • Blood pressure medications: Combining these may cause an increased risk of low blood pressure, especially when standing up.
No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

verifiedApollotooltip
  • Grapefruit and grapefruit juice: Can interfere with how your body breaks down this medicine, leading to dangerously high levels in your blood.
  • Alcohol: Increases the risk of liver damage and can worsen the intensity of skin flushing.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[ANTILIPEMICS]

FAQs

Tonact Plus Tablet is used to treat raised cholesterol levels in our body. Tonact Plus Tablet is a combination of two medicines, namely atorvastatin and nicotinic acid (vitamin B3). Atorvastatin is a lipid-lowering medication that blocks the enzyme required to make cholesterol in the body. It reduces the bad cholesterol (also known as low-density lipoproteins or LDL), triglycerides (TG) and increases the levels of good cholesterol (also known as high-density lipoproteins or HDL). On the other hand, Tonact Plus Tablet contains nicotinic acid, which is a form of vitamin B that further increases good cholesterol levels (HDL).
Yes. Muscle weakness can be the long-term side effects of Tonact Plus Tablet . You may have muscle fatigue or muscle pain which affects your daily activity. Try to contact a doctor if you have muscle weakness or fatigue.
Tonact Plus Tablet can raise your blood sugar a little. If you already have type 2 diabetes, please consult your doctor. Your doctor may adjust the dosage of Tonact Plus Tablet .
Yogurt has the ability to lower cholesterol to its probiotic content. Yogurt eaters have a better metabolic profile than those who did not eat yogurt.
Most of the time, high cholesterol levels are associated with an unhealthy lifestyle. The most common causes include obesity, smoking, genetic factors, sedentary lifestyle, unhealthy eating habits, and family history.
You are recommended not to stop taking Tonact Plus Tablet suddenly, as it may raise your cholesterol levels and increase the risk of stroke or heart attack. Always consult your doctor before stopping Tonact Plus Tablet .
Tonact Plus Tablet can cause an increase in blood sugar levels in people with diabetes. There is no need to stop Tonact Plus Tablet , but you should consult your diabetologist for advice on managing your diabetes. If necessary, the doctor may adjust your treatment or change the medication to avoid potential interactions.
Cholesterol is a precursor to lipids or fats in the body and is an essential component of cell membranes. However, an elevated level of LDL cholesterol (responsible for transporting cholesterol to tissues) can result in plaque formation, atherosclerosis, and narrowing of blood vessels. This restricts blood flow and increases the risk of coronary heart disease. Tonact Plus Tablet , containing Atorvastatin, helps reduce cholesterol build-up in the body. By lowering cholesterol levels, it lowers atherosclerosis, reducing the likelihood of heart attacks and delaying complications related to the heart and blood vessels.
Tonact Plus Tablet causes side effects such as constipation, nausea, vomiting, weakness, muscle pain, headache, dizziness, diarrhea, itching, peripheral edema, and increased glucose in the blood. However, consult a doctor if these persist longer.
No, Tonact Plus Tablet is not recommended for use during pregnancy or breastfeeding, as it can potentially harm the developing baby. If you become pregnant while taking this medicine, stop taking it and contact your doctor immediately. Talk to your doctor for safer alternatives.
The warming and flushing sensation is a common reaction to one of the active ingredients, which causes blood vessels near the skin to widen. Taking Tonact Plus Tablet with a low-fat bedtime snack and avoiding hot drinks, alcohol, or spicy foods around your dosing time can help. Talk to your doctor about whether taking a low-dose plain aspirin 30 minutes before your dose is safe and appropriate for you.
It is highly recommended to limit or avoid alcohol while taking Tonact Plus Tablet . Alcohol can increase the risk of liver damage and can significantly worsen skin flushing, a common side effect of this medicine. Talk to your doctor or pharmacist about safe alcohol consumption limits.
Yes, you should avoid eating grapefruit or drinking grapefruit juice, as it can increase the concentration of this medicine in your bloodstream and increase the risk of side effects. You should also limit foods high in saturated fats to help the medicine work effectively. Talk to your doctor or a dietitian for personalised dietary advice.
No, you should not stop taking Tonact Plus Tablet without consulting your healthcare provider. Cholesterol levels often rise again once the medication is stopped because it manages the condition rather than curing it. Talk to your doctor before making any changes to your treatment plan.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

Lupin Ltd, 3rd floor Kalpataru Inspire, Off. W E Highway, Santacruz (East), Mumbai 400 055. India Country of Origin: India
Other Info - TON0014
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