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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Tonact D 10 Tablet helps lower bad cholesterol (low-density lipoprotein-LDL) and triglycerides (fats) levels. Hence, it reduces the risk of heart attack and stroke in the future. It contains Atorvastatin and Cholecalciferol (Vitamin D3), which work by blocking liver enzymes, causing the liver to make less cholesterol. So, it increases the uptake and breakdown by the liver of cholesterol already in the blood. Thus, it lowers the levels of lipids known as cholesterol and triglycerides in the blood when lifestyle changes (like a low-fat diet) on their own have failed. It reduces the bad cholesterol and increases the good cholesterol by blocking our body's production of bad cholesterol. It also improves your body's ability to remove it from your blood. In some cases, you may experience allergic reactions, headache, blurred vision, pain, constipation, nausea, diarrhoea, muscle spasms, joint swelling, and back pain.
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Synonym :

ATORVASTATIN+VITAMIN D3

Manufacturer/Marketer :

Lupin Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Tonact D 10 Tablet

Tonact D 10 Tablet is a cholesterol-lowering medicine containing atorvastatin (statins or lipid reducer) and cholecalciferol (Vitamin D3). It helps lower bad cholesterol (low-density lipoprotein-LDL) and triglycerides (fats) levels. Hence, it reduces the risk of heart attack and stroke in the future. Two types of cholesterol are found in our body: good cholesterol (high-density lipoprotein) and bad cholesterol (low-density lipoprotein). Good cholesterol is good for our heart and helps reduce the bad cholesterol in our body. On the other hand, excess bad cholesterol (LDL) leads to the risk of heart diseases like heart attack and stroke.

Tonact D 10 Tablet works by blocking liver enzymes, causing the liver to make less cholesterol. So, Tonact D 10 Tablet increases the uptake and breakdown by the liver of cholesterol already in the blood. Thus, Tonact D 10 Tablet lowers the levels of lipids known as cholesterol and triglycerides in the blood when lifestyle changes (like a low-fat diet) on their own have failed. Tonact D 10 Tablet reduces the ‘bad’ cholesterol and increases the ‘good’ cholesterol by blocking our body’s production of ‘bad’ cholesterol. It also improves your body’s ability to remove it from your blood. Cholecalciferol is added to relieve the muscle pain caused due to atorvastatin. Collectively, Tonact D 10 Tablet helps reduce cholesterol levels in the blood.

The prescribed dose of Tonact D 10 Tablet is daily once a day at the same time. Your doctor will advise you on how often you take your tablets based on your medical condition. You can take Tonact D 10 Tablet with food or without food. It should be swallowed whole with a glass of water. Do not chew, bite, or break it. In a few cases, you may experience allergic reactions, headache, blurred vision, pain, constipation, nausea, diarrhoea, muscle spasms, joint swelling, and back pain. Most of these side effects of Tonact D 10 Tablet do not require medical attention and gradually resolve over time.

Tonact D 10 Tablet may cause a breakdown of skeletal muscle tissue, leading to kidney failure. This condition usually occurs in the elderly, people with kidney disease, and poorly controlled hypothyroidism (underactive thyroid). Tonact D 10 Tablet should not be prescribed to children less than ten years of age. You should contact a doctor before if you have had an allergic reaction to Tonact D 10 Tablet , have liver or kidney problems, pregnant or planning to get pregnant, are breastfeeding, have severe lung disease, have a previous heart attack or stroke caused by bleeding in the brain, have hypothyroidism, drink more than two servings of alcohol per day and have a muscle disorder (fibromyalgia). The efficiency of Tonact D 10 Tablet can be increased by taking low-fat or cholesterol-containing food and drinks.

Uses of Tonact D 10 Tablet

Treatment of High cholesterol, Prevention of heart attack and stroke.

Directions for Use

• Take Tonact D 10 Tablet with or without food as advised by your doctor. • Follow your doctor's instructions on the dosage and timing of this medication to ensure safe and effective use.• Swallow Tonact D 10 Tablet as a whole with a glass of water. • Do not crush, chew or break it.

Medicinal Benefits

Tonact D 10 Tablet contains Atorvastatin (fat or lipid reducer) and Cholecalciferol (Vitamin D3). Atorvastatin works by blocking liver enzymes, causing the liver to make less cholesterol. So, Tonact D 10 Tablet increases the uptake and breakdown by the liver of cholesterol already in the blood. Thus, Tonact D 10 Tablet lowers the levels of lipids known as cholesterol and triglycerides in the blood when lifestyle changes (like a low-fat diet) on their own have failed. Tonact D 10 Tablet reduces the ‘bad’ cholesterol and increases the ‘good’ cholesterol by blocking our body’s production of ‘bad’ cholesterol. It also improves your body’s ability to remove it from your blood. Cholecalciferol or Vitamin D3 is added to get relief from the musculoskeletal pain caused due to atorvastatin. Collectively, Tonact D 10 Tablet helps reduce the raised cholesterol level in the bloodstream.

How Tonact D 10 Tablet Works

Tonact D 10 Tablet works by blocking liver enzymes, causing the liver to make less cholesterol. So, Tonact D 10 Tablet increases the uptake and breakdown by the liver of cholesterol already in the blood. Thus, Tonact D 10 Tablet lowers the levels of lipids known as cholesterol and triglycerides in the blood when lifestyle changes (like a low-fat diet) on their own have failed. Tonact D 10 Tablet reduces the ‘bad’ cholesterol and increases the ‘good’ cholesterol by blocking our body’s production of ‘bad’ cholesterol. It also improves your body’s ability to remove it from your blood. Cholecalciferol is added to relieve the muscle pain caused due to atorvastatin. Collectively, Tonact D 10 Tablet helps reduce cholesterol levels in the blood.

Storage

Keep Tonact D 10 Tablet out of the sight and reach of children.

What if I have taken an overdose of Tonact D 10 Tablet

Do not take more than the prescribed dose of Tonact D 10 Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

Tonact D 10 Tablet may cause serious muscle problems (myopathy and rhabdomyolysis) and can lead to kidney failure. This condition usually occurs in the elderly, people with kidney disease, and poorly controlled hypothyroidism (underactive thyroid). Tonact D 10 Tablet should not be prescribed to children less than ten years of age. You should contact a doctor before if you have had an allergic reaction to Tonact D 10 Tablet , have a liver problem (jaundice, liver cirrhosis), or kidney problems, are pregnant or planning to get pregnancy, are breastfeeding, have severe lung disease, have a previous heart attack or stroke caused by bleeding in the brain, have hypothyroidism, drink more than two servings of alcohol per day and have a muscle disorder (fibromyalgia) and damaged muscle tissue (rhabdomyolysis). Also, calcium levels can decrease in blood, so intake calcium supplements to avoid unpleasant side effects.

Drug-Drug Interactions

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AtorvastatinNelfinavir
Severe

Drug-Drug Interactions

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How does the drug interact with Tonact D 10 Tablet:
Taking Tonact D 10 Tablet with Posaconazole can increase the blood levels of Tonact D 10 Tablet. This can increase the risk of side effects.

How to manage the interaction:
Although there is an interaction between posaconazole with Tonact D 10 Tablet, they can be taken together if advised by your doctor. However, contact the doctor if you experience unexplained muscle pain, weakness, fever, chills, joint pain or swelling, unusual bleeding, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark coloured urine, or yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.
AtorvastatinNelfinavir
Severe
How does the drug interact with Tonact D 10 Tablet:
Taking Tonact D 10 Tablet with nelfinavir may considerably raise Tonact D 10 Tablet levels in the blood. This can raise the chance of side effects (liver injury and rhabdomyolysis - an uncommon but serious illness that causes the breakdown of skeletal muscle tissue. Rhabdomyolysis occasionally results in kidney injury).

How to manage the interaction:
Although taking Tonact D 10 Tablet and cyclosporine together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience muscle pain, tenderness, or weakness especially accompanied by fever or dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, light colored stools, and/or yellowing of the skin or eyes, you should consult the doctor. Do not stop using any medications without talking to a doctor.
How does the drug interact with Tonact D 10 Tablet:
When Tonact D 10 Tablet and Fluconazole are taken together, the blood levels of Tonact D 10 Tablet may be significantly elevated.

How to manage the interaction:
Taking Tonact D 10 Tablet in conjunction with Fluconazole can result in an interaction, it can be taken if a doctor has advised it. However, if you experience muscle pain, tenderness, or weakness, accompanied by fever or dark-colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark-colored urine, light-colored stools, and/or yellowing of the skin or eyes, you should consult the doctor. Do not stop using any medications without talking to a doctor.
How does the drug interact with Tonact D 10 Tablet:
When Tonact D 10 Tablet and leflunomide are taken together it can increase the risk of liver problems.

How to manage the interaction:
Although taking Tonact D 10 Tablet and leflunomide together can result in an interaction, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, and/or yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Tonact D 10 Tablet:
Taking Tonact D 10 Tablet with indinavir may considerably raise Tonact D 10 Tablet levels in the blood.

How to manage the interaction:
Taking Tonact D 10 Tablet and indinavir together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience muscle pain, tenderness, or weakness especially accompanied by fever or dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, light colored stools, and/or yellowing of the skin or eyes, you should consult the doctor. Do not stop using any medications without talking to a doctor.
AtorvastatinConivaptan
Severe
How does the drug interact with Tonact D 10 Tablet:
Using conivaptan together with Tonact D 10 Tablet may significantly increase the blood levels of Tonact D 10 Tablet.

How to manage the interaction:
Taking Tonact D 10 Tablet with Conivaptan together can result in an interaction, but it can be taken if a doctor has advised it. You should also seek immediate medical attention if you develop fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, and/or yellowing of the skin or eyes. Do not stop using any medications without a doctor's advice.
AtorvastatinAmprenavir
Severe
How does the drug interact with Tonact D 10 Tablet:
Using Tonact D 10 Tablet together with amprenavir may significantly increase the blood levels of Tonact D 10 Tablet.

How to manage the interaction:
Although taking Tonact D 10 Tablet and Amprenavir together can cause an interaction, it can be taken if a doctor has suggested it. It's important to keep an eye on your health and talk to a doctor about any concerns. If you notice any of these signs - muscle pain, dark urine, fever, or fatigue - make sure to contact a doctor right away. They can help figure out what's going on and how to help you feel better. Do not stop using any medications without talking to a doctor.
How does the drug interact with Tonact D 10 Tablet:
Co-administration of Tonact D 10 Tablet with Ranolazine can possibly lead to elevated levels of Tonact D 10 Tablet in blood.

How to manage the interaction:
Co-administration of Tonact D 10 Tablet with Ranolazine can result in an interaction. It can be taken if a doctor has advised it. However, if you experience muscle pain, tenderness, or weakness especially accompanied by fever or dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, light-colored stools, and/or yellowing of the skin or eyes, you should consult the doctor. Do not discontinue the medications without consulting.
How does the drug interact with Tonact D 10 Tablet:
Combining Tonact D 10 Tablet with darunavir may profoundly enhance Tonact D 10 Tablet levels in the blood. This can raise the chance of side effects (liver injury and rhabdomyolysis, an uncommon but serious illness that causes the breakdown of skeletal muscle tissue. Rhabdomyolysis occasionally results in kidney injury).

How to manage the interaction:
Taking Tonact D 10 Tablet with darunavir can result in an interaction, it can be taken if a doctor has advised it. However, if you experience muscle pain, tenderness, or weakness, accompanied by fever or dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, light colored stools, and/or yellowing of the skin or eyes, you should consult the doctor. Do not stop using any medications without talking to a doctor.
AtorvastatinTipranavir
Severe
How does the drug interact with Tonact D 10 Tablet:
Using tipranavir together with Tonact D 10 Tablet may significantly increase the blood levels of Tonact D 10 Tablet.

How to manage the interaction:
Although taking Tipranavir and Tonact D 10 Tablet together can cause an interaction, it can be taken if a doctor has suggested it. You should seek immediate medical attention if you develop fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, and/or yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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ATORVASTATIN-10MG+CHOLECALCIFEROL-1000IUFruit juices
Moderate

Drug-Food Interactions

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ATORVASTATIN-10MG+CHOLECALCIFEROL-1000IUFruit juices
Moderate
Common Foods to Avoid:
Grapefruit Juice

How to manage the interaction:
Blood levels of Tonact D 10 Tablet can rise after consuming grapefruit juice. Before quitting the drug, speak to a doctor even though there may be an interaction. Additionally, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, exhaustion, nausea, vomiting, dark urine, or yellowing of the skin or eyes, you should consult a doctor. Without first consulting your doctor, never stop taking the medication.

Diet & Lifestyle Advise

  • Try aromatherapy, yoga, and meditation to help relax your body and mind.
  • Try to do breathing exercises to get more oxygen.
  • Eat a healthy diet rich in soluble fibre like beans, legumes, whole grain, flax, apples, and citrus fruits.
  • Try to replace most of your saturated fats with unsaturated fats that can reduce total cholesterol and LDL cholesterol quickly. Foods like avocados, olive oil, fatty fish, and nuts contain many heart-healthy unsaturated fats, so eating them regularly is beneficial.
  • Try to adopt a Mediterranean-style diet rich in olive oil, fruits, vegetables, nuts, whole grains, and fish, low in red meat and most dairy.
  • Try to give priority to more fruits and veggies in your daily meal as these contain antioxidants which help to lower LDL
  • Minimize the intake of added sugar. The American Heart Association (ADA) recommends that one should not eat more than 100 calories (25 grams) of added sugar for women and children and no more than 150 calories (37.5 grams) for men every day.
  • American Heart Association recommends that sodium chloride (table salt) intake should not exceed more than 2,300 mg per day as part of a healthy eating pattern.
  • As a precautionary measure, do not consume alcohol and quit smoking.

Habit Forming

No

Therapeutic Class

ANTIANGINALS
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Alcohol

Unsafe

Do not drink too much while taking this medicine. Drinking a lot of alcohol will make you more likely to get muscle problems (like myopathy and rhabdomyolysis) and liver problems (with side effects like yellowing of eye/skin and urine).

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Pregnancy

Unsafe

Tonact D 10 Tablet is pregnancy category X medicine. So it can cause damage to the fetus or unborn baby. Hence, Tonact D 10 Tablet is not recommended during pregnancy. Contact your doctor before taking Tonact D 10 Tablet .

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Breast Feeding

Caution

Tonact D 10 Tablet can pass into your breast milk and may harm your baby. So, before using Tonact D 10 Tablet , consult a doctor.

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Driving

Safe if prescribed

Tonact D 10 Tablet has no or negligible influence on the ability to drive and use machines.

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Liver

Caution

Tonact D 10 Tablet to be taken with caution, especially if you have a history of Liver diseases/conditions. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Tonact D 10 Tablet to be taken with caution, especially if you have a history of Kidney diseases/conditions. The dose may have to be adjusted by your doctor.

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Children

Unsafe

Tonact D 10 Tablet is not indicated in the treatment of patients below the age of 10 years.

Have a query?

FAQs

Tonact D 10 Tablet is used to treat high cholesterol. It lowers bad cholesterol (low-density lipoprotein-LDL) and triglycerides (fats) levels. Hence, it reduces the risk of heart attack and stroke in the future.

There's no strong evidence to suggest that taking Tonact D 10 Tablet will reduce fertility in either men or women. However, it is advisable to consult a doctor before taking it if you're likely to get pregnant or pregnant.

Increase your daily diet with fiber, fruits, vegetables, whole grains, and fish, and cut saturated fat as well. Stop smoking and drinking and try to work out every day as well.

No, you should not stop taking Tonact D 10 Tablet without consulting your doctor. Please take advice from the doctor before quitting.

People affected with hypothyroidism (underactive thyroid), muscle weakness, joint pain, kidney disease, diabetes, liver disease, uncontrolled epilepsy, high or low potassium level, or severely low blood pressure.

There is no firm clinical evidence stating that an intake of Tonact D 10 Tablet causes harm to the baby. However, Tonact D 10 Tablet passes into the breast milk and may harm the baby. It is advisable to consult a doctor if you are a nursing mother and taking Tonact D 10 Tablet .

Yogurt is a probiotic which can help in lowering the raised cholesterol level if taken with Tonact D 10 Tablet . Yogurt eaters have a better metabolic profile than those who didn't eat yogurt.

Egg yolks (yellow part of the egg) are high in cholesterol and rich in saturated fatty acids with a greater effect on our blood cholesterol levels. However, you can take a minimum of 3 whole eggs per day as eggs are considered a good source of HDL (good cholesterol). If you have high cholesterol, please consult a doctor regarding intake of the yolk part of the egg.

Taking Tonact D 10 Tablet has several benefits, including lowering cholesterol levels, reducing the risk of heart disease, heart attack, and stroke, and helping prevent cardiovascular events. It specifically lowers LDL cholesterol and triglycerides while increasing HDL cholesterol, ultimately reducing the risk of major cardiovascular events, heart attack, stroke, and death.

The use of Tonact D 10 Tablet may slightly increase the risk of developing type 2 diabetes. However, the benefits of taking this medication to reduce cardiovascular risk generally outweigh the potential risk of developing diabetes. Regular monitoring by your doctor is necessary to adjust treatment accordingly.

The best time to take Tonact D 10 Tablet is at night, before bedtime, as directed by your doctor. This is because the liver produces cholesterol at night, and taking the medication before bed can help reduce cholesterol production. However, always follow your doctor's specific instructions for taking the medication.

The commonly reported side effects of Tonact D 10 Tablet that may occur in some individuals include experiencing allergic reactions, headache, blurred vision, pain, constipation, nausea, diarrhoea, muscle spasms, joint swelling, and back pain. Most of these side effects do not require medical attention and gradually resolve over time. However, consult your doctor if any of these effects worsen or persist.

It is recommended to avoid or limit alcohol consumption while taking Tonact D 10 Tablet , as excessive drinking may increase the risk of muscle problems and liver issues. Consult your doctor for personalized advice.

You may feel tired when taking Tonact D 10 Tablet , as muscle weakness is a commonly reported side effect. However, the tiredness you are experiencing may be due to various reasons. To manage it, get plenty of rest and incorporate some energy-boosting measures. If you experience persistent and worsening tiredness, consult your doctor to determine the cause and find relief.

While taking Tonact D 10 Tablet , follow a healthy and balanced diet low in saturated fats and cholesterol, and limit or avoid grapefruit, fatty foods, alcohol, deep-fried foods, and sugary foods and drinks. Consult your doctor or a registered dietitian for personalized dietary advice.

If you forget a dose of Tonact D 10 Tablet , take it immediately when you remember. However, if your next dose is near, skip the missed dose and continue with your regular schedule. Never double dose to make up for a missed dose, as this may increase side effects.

If you're doing well and your cholesterol levels are controlled, your doctor may consider adjusting or tapering off the Tonact D 10 Tablet , but only after careful evaluation. Do not stop or adjust the medication on your own; this decision should only be made by your doctor.

Tonact D 10 Tablet contains Atorvastatin and Cholecalciferol. Atorvastatin lowers bad cholesterol (LDL) and triglycerides by blocking cholesterol production in the body. It also helps the liver remove fat from the blood. Cholecalciferol helps in supplementing Vitamin D3, managing deficiency and related bone problems, and enhancing atorvastatin's cholesterol-lowering effects while reducing muscle pain/damage.

If you are diabetic, consult your doctor before taking Tonact D 10 Tablet . Your doctor may need to monitor your blood sugar levels and adjust your diabetes treatment plan, as Tonact D 10 Tablet may affect blood sugar control.

Country of origin

India

Manufacturer/Marketer address

Lupin Ltd, 3rd floor Kalpataru Inspire, Off. W E Highway, Santacruz (East), Mumbai 400 055. India Country of Origin: India
Other Info - TON0057

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