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  3. Tolplus MR Tablet 10's

Tolplus MR Tablet 10's, Pack of 10
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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Tolplus MR Tablet is used to treat muscle spasms. It improves the movement of muscles and provides relief from pain and discomfort caused by the muscle spasm. It contains Tolperisone and Paracetamol, which works on the spinal cord and brain to relieve contraction or muscle stiffness. It also increases the supply of blood to the muscles. It may cause common side effects such as nausea, vomiting, dry mouth, dizziness, weakness and sleepiness. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Composition :

PARACETAMOL-500MG + TOLPERISONE-150MG

Manufacturer/Marketer :

Propel Healthcare

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Tolplus MR Tablet

Tolplus MR Tablet is used to treat muscle spasms. It improves the movement of muscles and provides relief from pain and discomfort caused by the muscle spasm. A muscle spasm occurs due to involuntary contractions of a muscle. A spasm may be a twitch in the muscle or may feel tight or hard, like a knot.

Tolplus MR Tablet is a combination of two drugs: Tolperisone (muscle relaxant) and Paracetamol (pain killer). Tolperisone works on the spinal cord and brain to relieve contraction or muscle stiffness. It also increases the supply of blood to the muscles. Paracetamol is an analgesic (pain reliever) and an antipyretic (fever reducer). It inhibits cyclo-oxygenase (COX) enzymes that further prevent the formation of chemical messengers called 'prostaglandins' (PGs). These prostaglandins are produced at injury sites and cause pain and swelling. By blocking the COX enzyme's effect, lesser PGs are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site.

Your doctor will decide the dose and duration based on the severity of your pain. Common side effects of Tolplus MR Tablet include nausea, vomiting, dry mouth, dizziness, weakness and sleepiness. These side effects are not familiar to everyone and vary individually.

Let your doctor know if you use any prescription and non-prescription medications before starting Tolplus MR Tablet . Inform your doctor if you have any liver, heart or kidney diseases, myasthenia gravis (fatigue of muscles) and phenylketonuria (a genetic disorder that causes an amino acid build-up, phenylalanine) and alcohol dependency. Consult your doctor before taking Tolplus MR Tablet if you are pregnant or planning for pregnancy. Tolplus MR Tablet may cause dizziness, so drive only if you are alert and focused. Tolplus MR Tablet should not be given to children as safety has not been established. Avoid consuming alcohol and Tolplus MR Tablet as it could lead to increased dizziness and risk of liver damage.

Uses of Tolplus MR Tablet

Treatment of Muscle spasms.

Directions for Use

• Take Tolplus MR Tablet with food to avoid stomach upset or as advised by a doctor.• Follow your doctor's instructions on the dosage and timing of this medication, to ensure the safety.• Swallow the medicine as a whole with glass of water.• Do not crush, break, or chew it.

Medicinal Benefits

Tolplus MR Tablet treats muscle spasms and consists of Tolperisone (muscle relaxant) and Paracetamol (pain killer). Tolperisone is a centrally-acting muscle relaxant. It works on the spinal cord and brain to relieve contraction or muscle stiffness. It also increases the supply of blood to the muscles. Paracetamol is an analgesic (pain reliever) and an antipyretic (fever reducer). It inhibits cyclo-oxygenase (COX) enzymes that further prevent the formation of chemical messengers called 'prostaglandins' (PGs). These prostaglandins are produced at injury sites and cause pain and swelling. By blocking the COX enzyme's effect, fewer PGs are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site.

How Tolplus MR Tablet Works

Tolplus MR Tablet is a combination of two drugs: Tolperisone (muscle relaxant) and Paracetamol (pain killer). Tolperisone works on the spinal cord and brain to relieve contraction or muscle stiffness. It also increases the supply of blood to the muscles. Paracetamol is an analgesic (pain reliever) and an antipyretic (fever reducer). It inhibits cyclo-oxygenase (COX) enzymes that further prevent the formation of chemical messengers called 'prostaglandins' (PGs). These prostaglandins are produced at injury sites and cause pain and swelling. By blocking the COX enzyme's effect, lesser PGs are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site.

Storage

Keep out of sight and reach of children.

What if I have taken an overdose of Tolplus MR Tablet

Do not take more than the prescribed dose of Tolplus MR Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

Inform your doctor if you have any liver, heart or kidney diseases, myasthenia gravis (fatigue of muscles), phenylketonuria (a genetic disorder that causes a build-up of an amino acid, phenylalanine), and alcohol dependency before starting Tolplus MR Tablet . Consult your doctor before taking Tolplus MR Tablet if you are pregnant, planning for pregnancy or breastfeeding. Tolplus MR Tablet may cause dizziness, so drive only if you are alert and focused. Avoid consuming alcohol along with Tolplus MR Tablet as it could lead to increased dizziness and risk of liver damage. Tolplus MR Tablet is not recommended in children as safety and efficacy is not established.

Diet & Lifestyle Advise

  • Exercising regularly helps in muscle stretching that is less likely to spasm, tear and sprain. Mild exercises such as jogging and walking are helpful for muscle stretching.
  • Massages can also be helpful.
  • Avoid freezing and hot temperatures.
  • Avoid wearing tight-fitting clothes, instead, wear loose garments.
  • Rest well and get plenty of sleep.
  • To avoid developing pressure sores, change your position at least every two hours.
  • Hot or cold therapy can haelp treat muscle spasms. Apply an ice-pack or hot-pack on the muscle for 15-20minutes.
  • Stay hydrated, drink plenty of water.

Habit Forming

No

Therapeutic Class

ANALGESICS
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Alcohol

Unsafe

You are recommended to avoid alcohol consumption while taking Tolplus MR Tablet . Alcohol intake, along with Tolplus MR Tablet , may cause increased dizziness and risk of liver damage.

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Pregnancy

Caution

Tolplus MR Tablet should be used with caution during pregnancy. Please consult your doctor before taking Tolplus MR Tablet .

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Breast Feeding

Caution

Tolplus MR Tablet should be used with caution during breastfeeding. Please consult your doctor before taking Tolplus MR Tablet .

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Driving

Caution

Tolplus MR Tablet may make you feel dizzy. Do not drive or operate machinery if you experience dizziness.

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Liver

Caution

Please consult your doctor since Tolplus MR Tablet should be used with caution in patients with liver impairment/liver disease.

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Kidney

Caution

Please consult your doctor since Tolplus MR Tablet should be used with caution in patients with kidney impairment/kidney disease.

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Children

Unsafe

Tolplus MR Tablet is not recommended in children as safety and efficacy is not established.

Have a query?

FAQs

Tolplus MR Tablet is used to treat muscle spasms. It improves the movement of muscles and provides relief from pain and discomfort caused by the muscle spasm.

Tolplus MR Tablet is a combination of two drugs: Tolperisone and Paracetamol. Tolperisone works on the spinal cord and brain to relieve contraction or muscle stiffness. Paracetamol works by blocking the action of certain chemical messengers that cause pain.

Tolplus MR Tablet is usually used for a short period and can be discontinued if there is no pain. However, it should be continued if advised by the doctor.

Tolplus MR Tablet is to be carefully administered in patients with alcohol dependency, kidney or liver damage, myasthenia gravis (fatigue of muscles) and phenylketonuria (a genetic disorder that causes the build-up of an amino acid, phenylalanine). Please consult your doctor before starting Tolplus MR Tablet if you have a medical history.

Tolplus MR Tablet may cause stomach upset; hence taking it with food will prevent you from getting an upset stomach.

Tolplus MR Tablet should be used cautiously in patients with kidney impairment/kidney disease. Therefore, please inform your doctor if you have any kidney disease before taking Tolplus MR Tablet . Thereby, your doctor will adjust the dose or prescribe a different medication.

The common side effects of Tolplus MR Tablet are nausea, vomiting, dry mouth, dizziness, weakness and sleepiness. Please consult your doctor if any of these side effects persist or worsen.

Take some rest, apply ice packs to reduce inflammation and heat packs to relax muscles and improve blood flow. Drink plenty of water to keep your muscles hydrated and prevent cramps. If your muscle pain is due to some other disease, follow your doctor's advice.

No, Tolplus MR Tablet does not cause any addiction. However, use it as prescribed by your doctor. Overuse or misuse of any medication can lead to unwanted side effects or dependency. Please consult your doctor if you have any concerns.

Tolplus MR Tablet should be used with caution in patients with liver impairment/liver disease, as Tolplus MR Tablet contains paracetamol known to cause harm to the liver, especially in doses above the recommended level. Also, avoid drinking alcohol while taking this medicine, as it may further increase your risk of liver damage. Consult your doctor immediately if you notice any early signs and symptoms of liver damage, such as fever, rash, loss of appetite, nausea, vomiting, fatigue, stomach pain, dark urine, yellow skin or eyes and abnormal liver enzymes.

Tolplus MR Tablet may take about an hour to see the initial benefit of pain relief after taking Tolplus MR Tablet . However, the exact time can vary depending on individual factors such as your metabolism and the severity of your condition. Please consult your doctor if you have any concerns or notice that the medication is not working as expected.

No, taking a higher-than-recommended dose may not be more effective; instead, it may increase the chances of having some serious side effects and toxicity. If you feel your current dose is insufficient relief, please consult your doctor for re-evaluation.

Store Tolplus MR Tablet in a cool and dry place at a temperature not exceeding 25°C. Keep away from sunlight and moisture. Keep out of the reach of children.

Country of origin

India

Manufacturer/Marketer address

No.86, 3Rd Cross Street, Varalakshmi Nagar, Madhuravoyal, Chennai-600095
Other Info - TOL0187

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Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Bayyarapu Mahesh KumarDoctor badge

Reviewed By

Bayyarapu Mahesh Kumar

M Pharmacy

Last Updated

Jul 18, 2025 | 6:43 AM IST

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Reference

  1. https://www.drugs.com/paracetamol.html
  2. https://www.japi.org/s2c46464/tolperisone
  3. https://www.medicines.org.uk/emc/files/pil.5916.pdf

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