apollo
0

Welcome User

Login/Sign Up

Home
Buy Medicines
Lab Tests
Doctor Consult
Circle Membership
insurance
Blogs
Contact Us
Privacy Policy
Return & Refunds
Need Help
Terms and Conditions
  1. Home
  2. Medicine

  3. Tolperitas-DSR Tablet 5's

Tolperitas-DSR Tablet 5's, Pack of 5 TabletS
Tolperitas-DSR Tablet 5's, Pack of 5 TabletS
Offers on medicine orders
All offers
axis icici
Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
TOLPERITAS-DSR TABLETS is used to reduce and relieve pain due to the muscle spasms (excessive tension in the muscles). It contains Diclofenac and Tolperisone, which work on the brain and spinal cord centres to relieve muscle stiffness or spasm and relieve pain and improve muscle's movement. Also, it reduces mild to moderate pain and inflammation. It may cause side effects such as nausea, diarrhoea, vomiting, heartburn, weakness, stomach pain/epigastric pain, sleepiness, dizziness, and appetite loss. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
Read more
rxMedicinePrescription drug

Whats That

tooltip

Also Explore

Momverse
Ask Apollo
insurance

Composition :

DICLOFENAC-100MG + TOLPERISONE-450MG

Manufacturer/Marketer :

Intas Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About TOLPERITAS-DSR TABLETS

TOLPERITAS-DSR TABLETS belongs to a class of medications called Non-steroidal anti-inflammatory drugs (NSAIDs) or pain killer. TOLPERITAS-DSR TABLETS is used to reduce and relieve pain due to the muscle spasms (excessive tension in the muscles). Muscle spasm is the sudden involuntary contractions of the muscle, which can be painful and uncomfortable. When the nerve impulses that control the muscle movements are damaged or interrupted, it could lead to muscle spasms.

TOLPERITAS-DSR TABLETS is a combination of two drugs, namely: Diclofenac and Tolperisone. Diclofenac is a pain killer (NSAIDs) while Tolperisone is a skeletal muscle relaxant. Diclofenac works by blocking the effect of a chemical messenger in your body, known as cyclo-oxygenase (COX) enzymes that make another chemical 'prostaglandins' (PG). These prostaglandins are produced at injury sites and cause pain and swelling. By blocking COX enzyme's effect, lesser PGs are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site. On the other hand, Tolperisone works on the brain and spinal cord centres to relieve muscle stiffness or spasm and relieve pain and improve muscle's movement.

Take TOLPERITAS-DSR TABLETS as prescribed by your doctor. You are advised to take TOLPERITAS-DSR TABLETS for as long as your doctor has prescribed it for you depending on your medical conditions. You may experience nausea, diarrhoea, vomiting, heartburn, weakness, stomach pain/epigastric pain, sleepiness, dizziness, and appetite loss. Most of these side effects of TOLPERITAS-DSR TABLETS do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

TOLPERITAS-DSR TABLETS can increase your risk of fatal heart attack or stroke. So, if you have had any recent heart surgery, do not use TOLPERITAS-DSR TABLETS. TOLPERITAS-DSR TABLETS increases the chances of stomach ulcers and bleeding.  Before taking this TOLPERITAS-DSR TABLETS, inform your doctor if you have any allergies, myasthenia gravis (weakness in muscles), asthma, and hay fever. To treat your condition effectually, continue taking TOLPERITAS-DSR TABLETS for as long as your doctor has prescribed. Do not take TOLPERITAS-DSR TABLETS if you are pregnant or breastfeeding unless prescribed. TOLPERITAS-DSR TABLETS causes drowsiness and dizziness, so drive with caution. TOLPERITAS-DSR TABLETS should not be given to children as safety and efficacy have not been established. Avoid consuming alcohol along with TOLPERITAS-DSR TABLETS as it could lead to increased drowsiness and dizziness, it might also increase the risk of stomach bleeding. Keep your doctor informed about your health condition and medicines to rule out any side-effects.

Uses of TOLPERITAS-DSR TABLETS

TOLPERITAS-DSR TABLETS is used in the treatment of muscle pain, spasms, and inflammation. The detailed uses of TOLPERITAS-DSR TABLETS are as follows:<br/>• Pain Relief: TOLPERITAS-DSR TABLETS provides effective relief from various painful conditions, including back pain, neck pain, joint and bone disorders, and post-operative pain, enhancing daily functioning and quality of life.<br/>• Muscle Spasms relief: TOLPERITAS-DSR TABLETS helps to relax muscles, alleviate spasms and tension, and improve mobility, allowing for better movement and reduced discomfort.<br/>• Anti-inflammatory Effects: TOLPERITAS-DSR TABLETS reduces inflammation and swelling, helping to alleviate pain and discomfort in conditions like arthritis, sprains, and strains.<br/>

Directions for Use

• Take TOLPERITAS-DSR TABLETS with food to avoid stomach upset or as advised by a doctor.• Follow your doctor's instructions on the dosage and timing of this medication, to ensure the safety.• Swallow the medicine as a whole with glass of water.• Do not crush, break, or chew it.

Medicinal Benefits

TOLPERITAS-DSR TABLETS belongs to a class of medications called Non-steroidal anti-inflammatory drugs (NSAIDs) or pain killers. TOLPERITAS-DSR TABLETS is a combination of two drugs, namely: Diclofenac and Tolperisone. Diclofenac is a pain killer (NSAIDs) while Tolperisone is a skeletal muscle relaxant. Diclofenac works by blocking the effect of a chemical messenger in your body, known as cyclo-oxygenase (COX) enzymes that make another chemical 'prostaglandins' (PG). These prostaglandins are produced at injury sites and cause pain and swelling. By blocking COX enzyme's effects, lesser PGs are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site. On the other hand, Tolperisone works on the brain and spinal cord centres to relieve muscle stiffness or spasm and relieve pain and improve muscle's movement. Altogether TOLPERITAS-DSR TABLETS relieves pain and relaxes the muscles.

How TOLPERITAS-DSR TABLETS Works

TOLPERITAS-DSR TABLETS is a combination of two drugs, namely: Diclofenac and Tolperisone. Diclofenac is a pain killer (NSAIDs) while Tolperisone is a skeletal muscle relaxant. Diclofenac works by blocking the effect of a chemical messenger in your body, known as cyclo-oxygenase (COX) enzymes that make another chemical 'prostaglandins' (PG). These prostaglandins are produced at injury sites and cause pain and swelling. By blocking COX enzyme's effect, lesser PGs are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site. On the other hand, Tolperisone works on the brain and spinal cord centres to relieve muscle stiffness or spasm and relieve pain and improve muscle's movement.

Storage

Keep this medicine out of the sight and reach of children.
Side effects of Tolperitas-DSR Tablet
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
  • High levels of liver enzymes need immediate medical attention.
  • Watch your diet and consume low-fat foods, like green leafy vegetables, fish, whole grains, nuts, etc.
  • Regularly do strengthening exercises to control your cholesterol levels.
  • Avoid drinking alcohol as it can affect your liver.
  • Focus on losing weight as it can help control cholesterol and maintain liver enzymes.
  • Practice yoga and meditation to improve liver functioning and overall health.
  • Limit processed foods and eat more vegetables and fruits.
  • Exercise at least 30 minutes every day.
  • Maintain a healthy weight.
  • Quit smoking as it can worsen kidney damage.
  • Control your blood pressure and blood glucose.
  • Limit salt intake and alcohol consumption.
  • Increased creatinine levels must be corrected immediately with the help of a doctor.
  • Reduce strenuous activities that can lead to muscle breakdown and production of creatinine.
  • Sleep for 7-8 hours per night to assist your body in repairing and rebuilding tissue.
  • Manage your blood pressure by implementing changes in lifestyle like losing weight, reducing stress and exercising regularly.
  • Avoid smoking and drinking alcohol.
Here are the few steps for dealing with itching caused by drug use:
  • Report the itching to your doctor immediately; they may need to change your medication or dosage.
  • Use a cool, damp cloth on the itchy area to help soothe and calm the skin, reducing itching and inflammation.
  • Keep your skin hydrated and healthy with gentle, fragrance-free moisturizers.
  • Try not to scratch, as this can worsen the itching and irritate your skin.
  • If your doctor prescribes, you can take oral medications or apply topical creams or ointments to help relieve itching.
  • Track your itching symptoms and follow your doctor's guidance to adjust your treatment plan if needed. If the itching persists, consult your doctor for further advice.
  • Include iron-rich foods like dark leafy vegetables, lean red meat, legumes and fish in your diet.
  • Consume vitamin C-rich foods as they aid iron absorption.
  • Limit tea, cocoa, and coffee as these can slow iron absorption.
  • Exercise regularly; however, do not overdo it.
  • Boost Vitamin K with leafy greens (spinach, kale), broccoli, cauliflower, and cabbage.
  • Include iron-rich foods like lean red meat, legumes, fortified cereals, and dark leafy greens.
  • Stay hydrated by drinking plenty of water.
  • Add Vitamin C-rich foods (citrus fruits, bell peppers) to enhance iron absorption.
  • Limit excessive alcohol and blood-thinning foods like garlic and certain herbs.
  • Engage in gentle exercise like walking, swimming, or yoga.
  • Monitor injuries and apply pressure to wounds promptly.
  • Schedule regular medical checkups for routine blood tests.

What if I have taken an overdose of TOLPERITAS-DSR TABLETS

Do not take more than the prescribed dose of TOLPERITAS-DSR TABLETS as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

TOLPERITAS-DSR TABLETS can increase your risk of fatal heart attack or stroke. So, if you have had any recent heart surgery, do not use TOLPERITAS-DSR TABLETS. Do not take TOLPERITAS-DSR TABLETS if you are allergic to TOLPERITAS-DSR TABLETS, have severe heart failure, have suffered bleeding problems such as bleeding from stomach or bowels while taking any pain killers or you have liver or kidney problems. Inform your doctor before taking TOLPERITAS-DSR TABLETS if you have or had high blood pressure, heart problems, high cholesterol, diabetes, asthma, liver and kidney problems. Do not take TOLPERITAS-DSR TABLETS if you are pregnant or breastfeeding unless prescribed. TOLPERITAS-DSR TABLETS causes drowsiness and dizziness, so drive only if you are alert. TOLPERITAS-DSR TABLETS should not be given to children as the safety have not been established. Avoid consuming alcohol and TOLPERITAS-DSR TABLETS as it could lead to increased drowsiness and increase the risk of stomach bleeding. Stop taking TOLPERITAS-DSR TABLETS and consult your doctor immediately if you have stomach pain or any signs of bleeding in intestine or stomach such as blood in stools. Do not take any other NSAID's for pain relief along with TOLPERITAS-DSR TABLETS unless prescribed. Keep your doctor informed about your health condition and medicines to rule out any side-effects.

Drug-Drug Interactions

verifiedApollotooltip
DiclofenacMeloxicam
Critical
DiclofenacMipomersen
Severe

Drug-Drug Interactions

Login/Sign Up

DiclofenacMeloxicam
Critical
How does the drug interact with Tolperitas-DSR Tablet:
Co-administration of Tolperitas-DSR Tablet with Meloxicam can increase the risk or severity of gastrointestinal side effects.

How to manage the interaction:
Taking Meloxicam with Tolperitas-DSR Tablet is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, consult your doctor immediately if you experience symptoms such as dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not stop any medication without doctor's advise.
DiclofenacMipomersen
Severe
How does the drug interact with Tolperitas-DSR Tablet:
Co-administration of Tolperitas-DSR Tablet with Mipomersen may cause liver problems.

How to manage the interaction:
Co-administration of Tolperitas-DSR Tablet and Mipomersen can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of hunger, fatigue, nausea, vomiting, abdominal pain, dark urine, pale stools, and/or yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.
DiclofenacAmiloride
Severe
How does the drug interact with Tolperitas-DSR Tablet:
Taking amiloride with Tolperitas-DSR Tablet can increase the risk of kidney problems, hyperkalemia(high potassium levels in blood), and high blood pressure.

How to manage the interaction:
There could be a possible interaction between Tolperitas-DSR Tablet and amiloride, but they can be taken together if your doctor has prescribed them. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
DiclofenacCelecoxib
Severe
How does the drug interact with Tolperitas-DSR Tablet:
Co-administration of Tolperitas-DSR Tablet with Celecoxib may increase the risk of stomach bleeding and ulcers.

How to manage the interaction:
Although there is a interaction between Tolperitas-DSR Tablet and Celecoxib, but it can be taken if your doctor has advised it. Consult a doctor if you experience symptoms like blood in your urine or stool (or a black stool), severe bruising, prolonged nosebleeds, feeling dizzy or lightheaded, weakness or severe headache, vomiting blood or coughing up blood, heavy menstrual bleeding (in women), difficulty breathing, or chest pain. Do not discontinue any medication without consulting a doctor.
DiclofenacDeferasirox
Severe
How does the drug interact with Tolperitas-DSR Tablet:
Co-administration of Tolperitas-DSR Tablet and deferasirox may increase your risk of developing stomach bleeding.

How to manage the interaction:
There may be a possible interaction between Tolperitas-DSR Tablet and deferasirox but they can be taken together if your doctor has prescribed them. However, consult your doctor immediately if you experience symptoms such as severe abdominal pain, bloating, sudden dizziness or lightheadedness, nausea, vomiting (especially with blood), loss of appetite, and/or black, tarry stools, increased or decreased urination, fluid retention, swelling, shortness of breath, muscle cramps, weakness, confusion, and irregular heart rhythm. Do not stop using any medications without first talking to your doctor.
DiclofenacFurosemide
Severe
How does the drug interact with Tolperitas-DSR Tablet:
Concomitant administration of Tolperitas-DSR Tablet and furosemide may decrease the therapeutic efficacy of furosemide and adversely affect renal function.

How to manage the interaction:
There may be a possible interaction between Tolperitas-DSR Tablet and furosemide, but they can be taken together if your doctor has prescribed them. However, consult your doctor immediately if you experience symptoms like nausea, dizziness, irregular heartbeats, altered blood pressure, tingling. Do not stop using any medications without first talking to your doctor.
DiclofenacPrasugrel
Severe
How does the drug interact with Tolperitas-DSR Tablet:
Taking prasugrel together with Tolperitas-DSR Tablet may increase the risk of bleeding.

How to manage the interaction:
Co-administration of Tolperitas-DSR Tablet and Prasugrel can lead to an interaction; it can be taken if advised by a doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult your doctor immediately. Do not stop using any medications without a doctor's advice.
DiclofenacAcalabrutinib
Severe
How does the drug interact with Tolperitas-DSR Tablet:
Taking acalabrutinib together with Tolperitas-DSR Tablet may increase the risk of bleeding.

How to manage the interaction:
Co-administration of Tolperitas-DSR Tablet and Acalabrutinib can lead to an interaction; it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult your doctor immediately. Do not stop using any medications without a doctor's advice.
DiclofenacTolmetin
Severe
How does the drug interact with Tolperitas-DSR Tablet:
Taking Tolperitas-DSR Tablet with Tolmetin may increase the risk of side effects.

How to manage the interaction:
There may be a possible interaction between Tolperitas-DSR Tablet and Tolmetin but can be taken if prescribed by doctor. However, consult your doctor immediately if you experience any unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not stop any medications without consulting a doctor.
DiclofenacSirolimus
Severe
How does the drug interact with Tolperitas-DSR Tablet:
Co-administration of Tolperitas-DSR Tablet with Sirolimus may increase the risk or severity of kidney problems.

How to manage the interaction:
Co-administration of Tolperitas-DSR Tablet and Sirolimus can lead to an interaction, but it can be taken if advised by a doctor. However, consult a doctor if you experience any symptoms like nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

Login/Sign Up

Diet & Lifestyle Advise

  • Exercising regularly helps in muscle stretching so that they are less likely to spasm, tear and sprain. Mild exercises such as jogging and walking are helpful for muscle stretching.
  • Massages can also be helpful.
  • Avoid freezing and hot temperatures.
  • Avoid wearing tight-fitting clothes, instead, wear loose garments.
  • Rest well, get plenty of sleep.
  • To avoid developing pressure sores, change your position at least every two hours.
  • Hot or cold therapy can help treat muscle spasms. Apply an ice-pack or hot-pack on the muscle for 15-20minutes.
  • Stay hydrated, drink plenty of water.

Habit Forming

No

Therapeutic Class

ANALGESICS

TOLPERITAS-DSR TABLETS Substitute

Substitutes safety advice

Product Substitutes

bannner image

Alcohol

Unsafe

Avoid consumption of alcohol while taking TOLPERITAS-DSR TABLETS as it may increase dizziness. It can also increase the risk of stomach bleeding.

bannner image

Pregnancy

Caution

Avoid taking TOLPERITAS-DSR TABLETS if you are pregnant unless prescribed by a doctor. Please consult your doctor if you have any concerns regarding this, your doctor will prescribe only if the benefits outweigh the risks.

bannner image

Breast Feeding

Unsafe

TOLPERITAS-DSR TABLETS must not be used during breastfeeding.

bannner image

Driving

Caution

TOLPERITAS-DSR TABLETS may cause sleepiness or dizziness. Do not drive or do anything needing concentration until you know how it affects you.

bannner image

Liver

Unsafe

Those who have severe liver problems should not take this TOLPERITAS-DSR TABLETS because TOLPERITAS-DSR TABLETS contains Tolperisone, which causes the most dangerous adverse in patients with liver disease.

bannner image

Kidney

Unsafe

Those who have severe kidney problems should not take this TOLPERITAS-DSR TABLETS because TOLPERITAS-DSR TABLETS contains Tolperisone, which causes the most dangerous adverse in patients with kidney disease.

bannner image

Children

Unsafe

TOLPERITAS-DSR TABLETS should not be given to children as the safety and effectiveness were not established.

Have a query?

FAQs

TOLPERITAS-DSR TABLETS is used to reduce and relieve pain due to the muscle spasms (excessive tension in the muscles).

TOLPERITAS-DSR TABLETS is a combination of two drugs: Diclofenac (Nonsteroidal Anti-Inflammatory Drug) and metaxalone (skeletal muscle relaxant). Diclofenac works by blocking the action of certain chemical messengers that cause pain. Tolperisone works on the spinal cord and centres in the brain to relieve contraction or muscle stiffness without decreasing strength.

TOLPERITAS-DSR TABLETS may impair mental and/or physical abilities required for the performance of heavy tasks like operating machinery or driving a motor vehicle, especially when used with alcohol.

Do not take TOLPERITAS-DSR TABLETS for longer durations as it might increase the risk of heart problems, liver problems and stomach bleeding/ulcer. Please consult a doctor before its use.

There are no recognized reports of any patient getting addicted to TOLPERITAS-DSR TABLETS.

If you are suffering from muscle pain due to overuse or muscle injury, you should take rest. Taking rest will help you to prevent any further injury and help you improve effectively. Make sure that you take enough sleep and try to decrease stress. Applying an ice pack to the altered area may help in reducing inflammation and pain. If your muscle pain is due to some other illness, follow the guidance of your doctor.

Take a missed dose as soon as you remember it. If it is close to the time for your next dose, skip the missed dose and go back to your regular time. Do not take 2 doses at the same time or extra doses.

Country of origin

India

Manufacturer/Marketer address

Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.
Other Info - TOL0181

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Bayyarapu Mahesh KumarDoctor badge

Reviewed By

Bayyarapu Mahesh Kumar

M Pharmacy

Last Updated

Jul 18, 2025 | 6:43 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.ogyei.gov.hu/kiseroirat/ph/ph_0000048451.pdf
  2. https://www.drugs.com/diclofenac.html
  3. https://www.japi.org/s2c46464/tolperisone
  4. https://www.medicines.org.uk/emc/product/2660/pil#gref

Buy best C.n.s Drugs products by

whatsapp Floating Button
Buy Now
Add to Cart