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Tolmake Trio Tablet is used to treat muscle spasms. It consists of Aceclofenac (NSAID), Tolperisone (muscle relaxant) and Paracetamol (pain killer). Tolperisone is a centrally acting muscle relaxant. It works on the spinal cord and brain to relieve contraction or muscle stiffness. It also increases the supply of blood to the muscles. On the other hand, both Aceclofenac and Paracetamol inhibit cyclo-oxygenase (COX) enzymes that further prevent the formation of chemical messengers called 'prostaglandins' (PGs). These prostaglandins are produced at injury sites and cause pain and swelling. By blocking the COX enzyme's effect, fewer PGs are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

ACECLOFENAC-100MG+PARACETAMOL-325MG+TOLPERISONE-150MG

Manufacturer/Marketer :

Uniprixx Laboratories Pvt Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Tolmake Trio Tablet

Tolmake Trio Tablet is an oral prescription medication primarily used to treat painful muscle spasms associated with musculoskeletal conditions. It helps relieve localized muscle stiffness, reduce swelling, and alleviate moderate-to-severe body pain. By targeting both the muscle spasm and the underlying pain, it helps restore physical mobility.

For best results, you should take Tolmake Trio Tablet consistently at the exact intervals prescribed by your doctor. It is highly recommended to take this tablet with food or immediately after a meal to protect your stomach from irritation. Incorporating light, low-impact daily stretching and staying well-hydrated can significantly support your recovery.

While most people tolerate Tolmake Trio Tablet well, some may experience mild side effects like drowsiness, dry mouth, or nausea. If you notice any serious issues, such as severe stomach pain, black stools, or a sudden yellowing of your skin or eyes, stop taking Tolmake Trio Tablet immediately and consult your doctor.

Before starting Tolmake Trio Tablet , it is crucial to discuss your complete medical history with your doctor. Do not take Tolmake Trio Tablet if you have a history of active stomach ulcers, severe heart failure, or severe liver or kidney disease. It is also not recommended for anyone who has experienced asthma attacks or severe allergic reactions after taking pain relievers.

Tolmake Trio Tablet can interact with alcohol, which increases the risk of drowsiness and liver damage, so you should avoid drinking while on this treatment. You must also check with your doctor before taking this if you are pregnant, planning to become pregnant, breastfeeding, or are an elderly individual, as special dosage adjustments may be needed.

Uses of Tolmake Trio Tablet

Tolmake Trio Tablet is used for relieving pain and muscle spasms. The detailed uses of Tolmake Trio Tablet are as follows:

  • Painful muscle spasms: Tolmake Trio Tablet helps by relaxing stiff, locked muscles and relieving the acute pain that triggers or accompanies these spasms.
  • Lower back pain: It targets deep tissue pain and severe stiffness in the lumbar region, helping you bend and move more easily.
  • Post-injury or post-surgical recovery: It manages localized swelling, muscle tension, and surgical site pain during physical rehabilitation.
     

Key Benefits

Tolmake Trio Tablet helps relieve pain, reduce inflammation, and relax painful muscle spasms. By combining three medicines with complementary actions, it helps improve movement, comfort, and recovery from painful muscle and joint conditions.

Benefits may include:

  • Helps relieve pain, muscle spasms, and inflammation at the same time.
  • Restores comfortable movement, making daily activities and physical therapy easier.
  • Helps reduce muscle stiffness and supports faster recovery after injuries or musculoskeletal conditions.
  • Promotes better sleep by relieving painful muscle tension and body aches.
  • Improves flexibility and overall physical function during recovery.
  • Enhances comfort and quality of life when used as prescribed.

Directions for Use

  • Take Tolmake Trio Tablet with or without food or as advised by a doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication, to ensure the safety.
  • Swallow the medicine as a whole with a glass of water.
  • Do not crush, break, or chew it.

How Tolmake Trio Tablet Works

Tolmake Trio Tablet contains Aceclofenac, Tolperisone, and Paracetamol. Aceclofenac: It is a non-steroidal anti-inflammatory drug (NSAID) that helps relieve pain and reduce inflammation by blocking the production of prostaglandins, the chemical messengers responsible for pain, swelling, and stiffness. This helps improve comfort and movement in painful musculoskeletal conditions. Tolperisone: It is a centrally acting muscle relaxant that works on the brain and spinal cord to reduce the nerve signals responsible for muscle tightness and spasms. This helps relax stiff muscles, improves mobility, and relieves discomfort caused by muscle spasm. Paracetamol: It is a pain reliever and fever-reducing medicine that works mainly in the brain to reduce the perception of pain and lower fever. It helps increase the body's pain threshold and provides additional pain relief when used with the other ingredients.
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Alcohol

Caution

Avoid alcohol consumption while taking Tolmake Trio Tablet . Alcohol intake, along with Tolmake Trio Tablet , may cause increased dizziness and risk of liver damage.

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Pregnancy

Caution

Please consult the doctor. There are no adequate and well-controlled studies on pregnant women. Your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

There is no substantial research yet on the use of Tolmake Trio Tablet in breastfeeding/nursing mothers. Let your doctor know if you are a nursing mother before taking Tolmake Trio Tablet ; your doctor will decide whether breastfeeding mothers can take Tolmake Trio Tablet or not.

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Driving

Caution

Tolmake Trio Tablet may make you feel dizzy. Do not drive or operate machinery if you experience dizziness.

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Liver

Caution

If you have liver problems, consult your doctor before taking Tolmake Trio Tablet as it may worsen your condition.

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Kidney

Caution

If you have kidney problems, consult your doctor before taking Tolmake Trio Tablet as it may worsen your condition.

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Children

Caution

Tolmake Trio Tablet is not recommended in children as safety and efficacy are not established.

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Heart

Caution

Tolmake Trio Tablet is contraindicated in patients with heart problems. Therefore, please consult your doctor before taking Tolmake Trio Tablet .

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Geriatrics

Consult your doctor

Tolmake Trio Tablet may require careful monitoring due to an increased risk of side effects in geriatric patients. Therefore, it is important to consult a doctor before administering Tolmake Trio Tablet to elderly individuals.

What if I have taken an overdose of Tolmake Trio Tablet

If you accidentally take more than the prescribed dose of Tolmake Trio Tablet , seek emergency medical care immediately or contact your local poison control center. Symptoms of an overdose can include severe nausea, vomiting, extreme drowsiness, dizziness, or difficulty breathing.

Diet & Lifestyle Advise

  • Stay hydrated: Drink plenty of water throughout the day. Dehydration can worsen muscle cramps and spasms.
  • Apply temperature therapy: Use a warm compress or heating pad to relax tight muscles, or an ice pack to reduce acute swelling and inflammation.
  • Engage in gentle movement: Avoid bed rest for long periods. Practice light stretching or short walks as tolerated to keep joints mobile and prevent further stiffness.
  • Maintain good posture: Pay attention to your sitting and standing posture, especially if you work at a desk, to reduce strain on your neck and back muscles.
  • Avoid heavy lifting: Refrain from lifting heavy objects or performing sudden, twisting movements while your muscles are healing.
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Have a query?

How Soon It Starts Working

The time required for Tolmake Trio Tablet to start to work: The time required for Tolmake Trio Tablet to show its action is not clinically established. The time for which the effects of Tolmake Trio Tablet last: The duration of action for Tolmake Trio Tablet is not clinically established.

What if you forget to take Tolmake Trio Tablet

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and resume your regular schedule. Do not take a double dose to make up for a missed one.

Storage

•Store Tolmake Trio Tablet tablets at room temperature, ideally between 15°C and 30°C (59°F and 86°F).

Drug Warnings

  • Avoid driving: Since Tolmake Trio Tablet can cause drowsiness and dizziness, do not drive, operate machinery, or perform hazardous tasks until you know how it affects you.
  • Do not double up on pain relievers: Avoid taking other medications containing acetaminophen or non-steroidal anti-inflammatory drugs (NSAIDs) while using Tolmake Trio Tablet , as this greatly increases the risk of liver damage and stomach ulcers.
  • Limit alcohol consumption: Drinking alcohol while taking Tolmake Trio Tablet can cause severe drowsiness and significantly increases your risk of liver damage.
  • Watch for signs of bleeding: If you experience frequent nosebleeds, easy bruising, or find blood in your stool, stop taking Tolmake Trio Tablet and speak to your doctor immediately.
  • Stay alert to skin changes: Stop using Tolmake Trio Tablet and contact a doctor immediately if you notice any unexplained skin rash, itching, or redness.

verifiedApollotooltip

  • Blood thinners (e.g., warfarin): Taking these medicines alongside Tolmake Trio Tablet may increase the risk of internal bleeding.
  • NSAIDs or pain relievers (e.g., ibuprofen, naproxen): Using these medicines with Tolmake Trio Tablet may increase the risk of stomach irritation, ulcers, and gastrointestinal bleeding.
  • Blood pressure medicines (e.g., enalapril, losartan): Tolmake Trio Tablet may reduce the effectiveness of these medicines and increase the risk of kidney problems.
  • Muscle relaxants (e.g., tizanidine, baclofen): Taking these medicines together may increase drowsiness, dizziness, and muscle weakness.
  • Sedatives (e.g., diazepam, zolpidem): Combining these medicines with Tolmake Trio Tablet may cause excessive drowsiness, slowed breathing, and impaired alertness.

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verifiedApollotooltip
  • Alcohol: Avoid drinking alcohol while taking Tolmake Trio Tablet , as it may increase drowsiness, stomach bleeding, and the risk of liver damage.

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANALGESICS, MUSCLE RELAXANTS]

FAQs

Tolmake Trio Tablet is used to treat Muscle spasms.
Tolmake Trio Tablet is a combination of three drugs: Aceclofenac, Tolperisone and Paracetamol. Tolperisone works on the spinal cord and brain to relieve contraction or muscle stiffness. Both Aceclofenac and Paracetamol work by blocking the action of certain chemical messengers that cause pain.
Yes, Tolmake Trio Tablet may cause nausea or vomiting in some people. To avoid the same, you should take Tolmake Trio Tablet with milk or food. In case you are still experiencing excessive nausea while consuming Tolmake Trio Tablet , speak with your doctor right away.
No, there aren't any cases of addictions to Tolmake Trio Tablet .
Before taking Tolmake Trio Tablet , inform your doctor about any allergies, medical conditions like liver, heart, or kidney disease, and other health issues like myasthenia gravis or phenylketonuria. Also, tell your doctor if you're pregnant, planning to get pregnant, or breastfeeding. Additionally, be cautious when driving and avoid alcohol consumption while taking Tolmake Trio Tablet , as it may cause dizziness and increase the risk of liver damage.
Tolmake Trio Tablet contains aceclofenac (NSAID), tolperisone (muscle relaxant), and paracetamol (pain killer). It is used in the treatment of muscle spasms.
Yes, you can take Tolmake Trio Tablet with vitamin B-complex if advised by the doctor. Tolmake Trio Tablet helps relieve pain, while vitamin B-complex addresses any underlying vitamin deficiencies that may be contributing to your symptoms. However, it is best to consult your doctor before taking with Tolmake Trio Tablet .
Long-term use of Tolmake Trio Tablet may harm your kidneys. Normally, kidneys produce prostaglandins, which help protect them from damage. However, painkillers like Tolmake Trio Tablet reduce prostaglandin levels, increasing the risk of kidney damage with prolonged use.
Taking Tolmake Trio Tablet in higher doses will not necessarily make it more effective. Taking higher than recommended doses may cause excessive drowsiness and increase the risk of liver damage and potential harm. Always follow the prescribed dosage and consult your doctor if you feel the medication is not providing adequate relief.
Be cautious when taking Tolmake Trio Tablet , as they can cause liver damage, especially if taken more than the recommended dose. Additionally, avoid consuming alcohol while on this medication, as it can increase your risk of liver damage. To ensure safe usage, always follow the prescribed dosage.
Tolmake Trio Tablet should be stored in a cool and dry place away from sunlight. Do not flush Tolmake Trio Tablet down the toilet or pour it down the drain. Dispose of any expired or unused tablets responsibly, by returning them to your pharmacist or a designated drug disposal facility.
The common side effects of Tolmake Trio Tablet may include nausea (feeling sick), constipation, flatulence, diarrhoea, dizziness, sleepiness, sweating, abdominal pain, and weakness. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
It is highly recommended to take Tolmake Trio Tablet with food or shortly after a meal. This helps shield your stomach lining and reduces the likelihood of experiencing nausea or stomach pain. Talk to your doctor if you still experience stomach discomfort.
Yes, drowsiness and dizziness are common side effects of Tolmake Trio Tablet due to its muscle-relaxing component. Avoid driving, operating heavy machinery, or doing any activity that requires mental alertness until you know how Tolmake Trio Tablet affects you. Talk to your doctor if drowsiness persists.
No, you should strictly avoid alcohol while taking Tolmake Trio Tablet . Alcohol can worsen drowsiness, increase dizziness, and significantly raise the risk of severe liver damage and stomach bleeding. Talk to your doctor for more safety advice.
Tolmake Trio Tablet is generally not recommended during pregnancy, particularly in the third trimester, as it may harm the unborn baby or cause complications during delivery. If you are pregnant or planning to conceive, talk to your doctor to discuss safer alternatives.
You should avoid taking other over-the-counter pain relievers, especially those containing acetaminophen or anti-inflammatory drugs, while on Tolmake Trio Tablet . Doing so can lead to dangerous accidental overdoses, liver damage, or stomach ulcers. Talk to your doctor before combining any medications.
Your doctor will prescribe Tolmake Trio Tablet for the shortest duration necessary to treat your acute muscle spasm and pain. Long-term use is generally avoided to prevent risks to your stomach, kidneys, and liver. Talk to your doctor if your pain does not improve.
You should stop taking Tolmake Trio Tablet immediately and seek urgent medical care if you develop a skin rash, itching, or peeling skin. These can be early signs of a serious allergic reaction or a severe skin condition. Talk to your doctor right away.
Tolmake Trio Tablet is specifically prescribed when joint or back pain is accompanied by painful, rigid muscle spasms. It is not standard therapy for chronic arthritis unless muscle spasms are a primary issue. Talk to your doctor to find the most appropriate treatment for arthritis.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

Plot No-556/2915, Badajena Sahi Sishupalgarh, Ps-Dhauli Bhubaneswar Khordha Or 751002 In
Other Info - TOL0263

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