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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

TOLAZ 2.5MG TABLET is used in the treatment of oedema (fluid retention) caused by kidney disease or heart failure. Additionally, it is also used alone or in combination with other medicines to treat high blood pressure. It contains Metolazone, which works by causing the kidneys to reduce the amount of water and salt in the body by increasing the amount of urine. Thereby, it helps reduce fluid retention and lowers blood pressure. In some cases, it may cause side effects such as nausea, vomiting, diarrhoea, and constipation. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Whats That

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Composition :

METOLAZONE-2.5MG

Manufacturer/Marketer :

Torrent Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About TOLAZ 2.5MG TABLET

TOLAZ 2.5MG TABLET belongs to the group of medicines called diuretics indicated in the treatment of oedema (fluid retention) caused by kidney disease or heart failure. Additionally, it is also used alone or in combination with other medicines to treat high blood pressure. 

TOLAZ 2.5MG TABLET contains Metolazone, which works by causing the kidneys to reduce the amount of water and salt in the body by increasing the amount of urine. Thereby, it helps reduce fluid retention and lowers blood pressure.

In some cases, TOLAZ 2.5MG TABLET may cause side effects such as nausea, vomiting, diarrhoea, and constipation. Most of these side effects may not require medical attention and resolve gradually over time. However, you are advised to talk to the doctor if the side effects persist or worsen.

Do not take TOLAZ 2.5MG TABLET if you are allergic to any of its components or if you are pregnant or breastfeeding. TOLAZ 2.5MG TABLET is not recommended for children below 18 years. Keep the doctor informed about your health condition and medications to rule out any unpleasant side effects/interactions.

Uses of TOLAZ 2.5MG TABLET

TOLAZ 2.5MG TABLET is used in the treatment of edema (fluid retention) and hypertension (high blood pressure). The detailed uses of TOLAZ 2.5MG TABLET are as follows:<br/>• Treatment of Edema: TOLAZ 2.5MG TABLET is a diuretic medication used to treat fluid retention (edema) in patients with congestive heart failure, liver disease, or kidney disorders.<br/>• Management of Hypertension: TOLAZ 2.5MG TABLET is also used to lower high blood pressure by removing excess fluid from the body, reducing blood volume, and relaxing blood vessels.<br/>

Directions for Use

• Take TOLAZ 2.5MG TABLET with or without food as advised by your doctor.• It is advised to take TOLAZ 2.5MG TABLET once daily; however, follow your doctor’s recommendation regarding the dosage and duration.• Swallow TOLAZ 2.5MG TABLET as a whole with a glass of water.• Do not crush, break, or chew it.

Medicinal Benefits

TOLAZ 2.5MG TABLET contains Metolazone, which is indicated in the treatment of oedema (fluid retention) accompanying congestive heart failure or renal diseases. Besides this, it is also used alone or in combination with other medicines to treat high blood pressure. TOLAZ 2.5MG TABLET causes the kidneys to reduce the amount of water and salt in the body by increasing the amount of urine. Thereby, it helps reduce fluid retention and lowers blood pressure.

How TOLAZ 2.5MG TABLET Works

TOLAZ 2.5MG TABLET contains Metolazone, which works by causing the kidneys to reduce the amount of water and salt in the body by increasing the amount of urine. Thereby, it helps reduce fluid retention and lowers blood pressure.

Storage

Keep this medicine out of sight and reach of children.
Side effects of Tolaz 2.5mg Tablet
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Eat fatty fish rich in omega-3 fatty acids to reduce inflammation.
  • Add whole grains such as brown rice, quinoa, and whole wheat bread to your diet for a nutritional boost.
  • Add nuts and seeds like almonds, walnuts, chia seeds for anti-inflammatory benefits.
  • Eat dark leafy greens like spinach, kale, collard greens for antioxidants.
  • Include berries like blueberries, strawberries, raspberries for anti-inflammatory properties.
  • Rest and take a break from usual activities.
  • Apply ice for 15-20 minutes, 3 times a day to reduce pain and inflammation.
  • Use compression with a stretchable bandage or wrap to lessen swelling and provide support.
  • Avoid strenuous activities and rest the affected area.
  • Try light stretching with gentle exercises to maintain flexibility.
  • Consider OTC pain medications like ibuprofen or acetaminophen but consult a doctor before taking any medication.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.

What if I have taken an overdose of TOLAZ 2.5MG TABLET

Do not take more than the prescribed dose of TOLAZ 2.5MG TABLET as it may cause overdose. The symptoms of overdose include stomach upset, drowsiness, fainting, dizziness, coma and slow or difficult breathing. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Do not take TOLAZ 2.5MG TABLET if you are allergic to any of its components, if you have anuria (unable to urinate), hepatic precoma or coma, or if you are pregnant or breastfeeding. Inform the doctor if you have liver or kidney problems, fluid or electrolyte imbalance, Addison’s disease (syndrome due to low level of corticosteroid hormones secretion), diabetes, gout (high levels of uric acid in the blood), systemic lupus erythematosus (an inflammatory disease of connective tissue), porphyria, eye pain or vision problems, or high cholesterol. Let the doctor know if you are taking any other medicines, including supplements or herbal products.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Tolaz 2.5mg Tablet:
When Ropinirole is taken with Tolaz 2.5mg Tablet, it may reduce the effectiveness of ropinirole.

How to manage the interaction:
Taking Ropinirole with Tolaz 2.5mg Tablet is not recommended as it can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as drowsiness, low blood pressure, dizziness, and lightheadedness. Do not stop using any medications without consulting doctor.
How does the drug interact with Tolaz 2.5mg Tablet:
Taking Tolaz 2.5mg Tablet with Potassium chloride can increase the risk of stomach ulcers, bleeding, and gastrointestinal injury.

How to manage the interaction:
Co-administration of Tolaz 2.5mg Tablet and Potassium chloride is not recommended as it leads to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like severe abdominal pain, bloating, sudden dizziness or lightheadedness, nausea, vomiting (especially with blood), loss of appetite, and/or black, tarry stools, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Tolaz 2.5mg Tablet:
Taking Tolaz 2.5mg Tablet with Pramipexole can increase the risk and severity of side effects and reduce the effectiveness of Pramipexole.

How to manage the interaction:
Co-administration of Tolaz 2.5mg Tablet and Pramipexole is not recommended as it leads to an interaction, it can be taken if advised by a doctor. If you experience any symptoms such as drowsiness, dizziness, and lightheadedness, contact a doctor immediately. Avoid driving or operating dangerous machinery, and be careful while getting up from a sitting or lying position. Do not discontinue any medications without consulting a doctor.
OlanzapinePotassium citrate
Critical
How does the drug interact with Tolaz 2.5mg Tablet:
Taking Tolaz 2.5mg Tablet with Potassium citrate can increase the irritant effects of potassium on your stomach and upper intestine.

How to manage the interaction:
Co-administration of Tolaz 2.5mg Tablet and Potassium citrate is not recommended as it leads to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like severe abdominal pain, bloating, sudden dizziness or lightheadedness, nausea, vomiting (especially with blood), loss of appetite, and/or black, tarry stools, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Tolaz 2.5mg Tablet:
Coadministration of Tolaz 2.5mg Tablet and ciprofloxacin can increase blood levels and the effects of Tolaz 2.5mg Tablet, which may lead to side effects.

How to manage the interaction:
Although taking ciprofloxacin and Tolaz 2.5mg Tablet together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, if you experience difficulty swallowing, low blood pressure, irregular heart rhythm, and seizures(fits) consult the doctor immediately. Do not stop using any medications without talking to a doctor.
OlanzapineIohexol
Severe
How does the drug interact with Tolaz 2.5mg Tablet:
The combined use of Iohexol and Tolaz 2.5mg Tablet can increase the risk of seizures as Iohexol be injected directly into the spine.

How to manage the interaction:
Taking Tolaz 2.5mg Tablet with Iohexol together can possibly result in an interaction, but it can be taken if your doctor has advised it. If you have seizures or a head injury, it's important to contact your doctor right away. Do not stop using any medications without a doctor's advice.
How does the drug interact with Tolaz 2.5mg Tablet:
Combining of Tolaz 2.5mg Tablet and Bupropion can increase the risk of seizures (fits).

How to manage the interaction:
Co-administration of bupropion along with Tolaz 2.5mg Tablet can lead to an interaction, but it can be taken if recommended by a doctor. While taking these medications, you should avoid tasks that need mental attention, such as driving or operating dangerous machinery. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Tolaz 2.5mg Tablet:
Combining Tolaz 2.5mg Tablet with Clozapine can increase the risk of serious cardiovascular side effects such as low blood pressure and cardiac or respiratory arrest.

How to manage the interaction:
Although taking Tolaz 2.5mg Tablet and Clozapine together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you have any of these symptoms, like dizziness, drowsiness, blurred vision, confusion, dry mouth, abdominal cramping, constipation, difficulty urinating, heat intolerance, palpitation, and irregular heart rhythm, it's important to contact a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Tolaz 2.5mg Tablet:
Using Morphine together with Tolaz 2.5mg Tablet can increase the risk of central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although taking Tolaz 2.5mg Tablet and Morphine together can lead to an interaction, it can be taken if a doctor has suggested it. If you experience dizziness, drowsiness, difficulty concentrating, and impairment in judgment contact a doctor immediately. You should avoid driving or operating hazardous machinery. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Tolaz 2.5mg Tablet:
The combined use of Ondansetron and Tolaz 2.5mg Tablet can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Co-administration of Ondansetron and Tolaz 2.5mg Tablet can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, heart palpitations, diarrhea, or vomiting, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Follow a low-salt and low-fat diet. 
  • Exercise regularly for at least 30 minutes on most days.
  • Eat a diet rich in whole grains, vegetables, and fruits.
  • Avoid smoking and alcohol consumption.
  • Maintain a healthy weight with proper diet and exercise.
  • Manage stress with meditation, yoga, and massage.

Habit Forming

No

Therapeutic Class

ANTI- HYPERTENSIVES
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Alcohol

Caution

Consuming alcohol in combination with TOLAZ 2.5MG TABLET may cause a decrease in blood pressure, leading to dizziness and fatigue. Therefore, avoid alcohol consumption during treatment with TOLAZ 2.5MG TABLET.

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Pregnancy

Unsafe

TOLAZ 2.5MG TABLET is not recommended during pregnancy. Consult the doctor if you are pregnant, think you may be pregnant or planning for pregnancy.

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Breast Feeding

Unsafe

TOLAZ 2.5MG TABLET is not recommended during breastfeeding. Consult the doctor if you are breastfeeding.

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Driving

Caution

TOLAZ 2.5MG TABLET may cause dizziness and fatigue. Avoid driving or operating heavy machinery if you experience these symptoms.

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Liver

Consult your doctor

Please consult the doctor if you have liver problems or any concerns regarding this.

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Kidney

Caution

TOLAZ 2.5MG TABLET should be used with caution in patients with severe renal impairment. Please consult the doctor if you have kidney problems or any concerns regarding this.

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Children

Unsafe

TOLAZ 2.5MG TABLET is not recommended for children below 18 years as safety and effectiveness have not been established.

Have a query?

FAQs

TOLAZ 2.5MG TABLET is used to treat fluid retention (oedema) and high blood pressure (hypertension).

TOLAZ 2.5MG TABLET helps the kidneys remove water from the body and lower blood pressure.

Please do not stop taking TOLAZ 2.5MG TABLET without consulting your doctor. To treat your condition effectually, continue taking TOLAZ 2.5MG TABLET for as long as your doctor has prescribed it to you. Do not be reluctant to speak with your doctor if you experience any difficulty while taking TOLAZ 2.5MG TABLET.

TOLAZ 2.5MG TABLET may make your skin sensitive to sunlight. Therefore, avoid prolonged or unnecessary sun exposure. Wear protective clothing and use sunscreen whilst going out.

TOLAZ 2.5MG TABLET may cause light-headedness, dizziness, and fainting when you get up too quickly from a lying position. To prevent this, get out of bed slowly, resting your feet on the floor for a few minutes before standing up.

No, TOLAZ 2.5MG TABLET is not a steroid. It is a diuretic medication used to treat oedema (fluid retention) caused by kidney disease, heart failure or other medical conditions.

TOLAZ 2.5MG TABLET contains Metolazone, which is used in the treatment of oedema (fluid retention) caused by kidney disease or heart failure. Additionally, it is also used alone or in combination with other medicines to treat high blood pressure.

While using TOLAZ 2.5MG TABLET, you should know that this medication may make you dizzy or drowsy. Be cautious and avoid activities that require focus and attention, such as driving or operating machinery.

TOLAZ 2.5MG TABLET typically starts working within 1.5 hours, although the exact timing can vary from person to person. Factors such as the severity of the condition, dosage, and individual metabolism can influence how quickly it takes effect. Once it starts working, the effects of TOLAZ 2.5MG TABLET can last for up to 24 hours.

It is essential to exercise caution when considering taking any medications together including fexofenadine. Unless your doctor recommends, taking TOLAZ 2.5MG TABLET and Fexofenadine together is generally not advisable. Potential interactions or side effects may occur, and your doctor can assess whether the combination is safe and necessary for your specific situation. Always consult your doctor or healthcare professional before combining medications, and never take medications without their recommendation.

Take TOLAZ 2.5MG TABLET exactly as prescribed by your doctor to manage your high blood pressure (hypertension). This is a long-term treatment, which means you'll need to take it continuously for an extended period. Regular check-ups with your doctor are crucial to monitor your blood pressure, adjust your dosage as needed, and ensure TOLAZ 2.5MG TABLET works effectively and safely for you. Following your doctor's instructions and attending regular check-ups can effectively manage your high blood pressure and reduce the risk of related health issues.

Continue taking TOLAZ 2.5MG TABLET as directed by your doctor. The duration of treatment varies depending on your condition and response to TOLAZ 2.5MG TABLET. Follow your doctor's instructions and schedule regular check-ups to monitor your progress and adjust treatment as needed.

TOLAZ 2.5MG TABLET may cause side effects such as nausea, vomiting, diarrhoea, and constipation. Most of these side effects may not require medical attention and resolve gradually over time. However, you are advised to talk to the doctor if the side effects persist or worsen.

Country of origin

India

Manufacturer/Marketer address

Off. Ashram Road, Ahmedabad - 380 009., Gujarat, India
Other Info - TOL0009

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