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  3. Tilstigmin Tablet 10's

Tilstigmin Tablet 10's, Pack of 10 TABLETS
Tilstigmin Tablet 10's, Pack of 10 TABLETS
Tilstigmin Tablet 10's, Pack of 10 TABLETS
Tilstigmin Tablet 10's, Pack of 10 TABLETS
Tilstigmin Tablet 10's, Pack of 10 TABLETS
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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Tilstigmin Tablet is used to treat myasthenia gravis (muscle problems), reverse the effect of muscle relaxants, improve small intestinal movements and reduce urinary retention after surgical procedures. It contains Neostigmine which increases levels of a neurotransmitter involved in communication between nerve impulses and muscle movements. This medicine may sometimes cause side effects such as nausea, vomiting, abdominal cramps, diarrhoea, dizziness, headache, and dry mouth. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Composition :

NEOSTIGMINE-15MG

Manufacturer/Marketer :

Tablets India Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Tilstigmin Tablet

Tilstigmin Tablet is used to treat myasthenia gravis. Tilstigmin Tablet is also used when the normal movements of the intestine are absent and to treat post-operative urinary retention.

Tilstigmin Tablet contains 'Neostigmine.' It increases levels of a neurotransmitter called acetylcholine by stopping the excess cholinesterase activity (an enzyme required to break down acetylcholine) involved in communication between nerve impulses and muscle movements. Neurotransmitters are chemical messengers that transmit the message from one nerve cell to another nerve cell, muscle cell, or gland cell. Thus, Tilstigmin Tablet helps with proper muscle functioning and prevents muscle weakness.

Take this medicine as prescribed by your doctor. In some cases, you may experience common side effects, such as nausea, vomiting, abdominal cramps, diarrhoea, increased saliva production, dizziness, headache, trouble sleeping, and dry mouth. These side effects are not familiar to everyone and vary individually. If you notice any side effects that are not manageable, please consult your doctor.

Inform your doctor before using Tilstigmin Tablet if you have a history of liver, heart or kidney diseases, asthma, stomach ulcer, fits, Parkinson’s disease, overactive thyroid, and irritability of the vagus nerve (connects to the abdomen from the brain) that causes excess bowel contractions. Before starting this medicine, you must let your doctor know if you are pregnant, planning to conceive, or a breastfeeding mother. Avoid consuming alcohol during the course to prevent unwanted side effects. Tilstigmin Tablet can be given to children if prescribed by the doctor; the dose depends on the child’s age and weight.

Uses of Tilstigmin Tablet

Treatment of Myasthenia gravis and post-operative urinary retention.

Have a query?

Directions for Use

• Tilstigmin Tablet can be taken with or without food. However, taking it with food may help reduce stomach upset.• It is usually taken twice daily or as prescribed by your doctor.• Swallow Tilstigmin Tablet as a whole with a glass of water.• Do not crush, chew, or break it.

Medicinal Benefits

Tilstigmin Tablet belongs to the group of medicines called 'anticholinesterase agents/cholinesterase inhibitors and is used to treat myasthenia gravis (muscle weakness). Tilstigmin Tablet contains 'Neostigmine'. It works by stopping the excessive activity of cholinesterase, helping the muscles work correctly. Additionally, Tilstigmin Tablet is used to treat urinary retention and reverses the effects of neuromuscular blocking agents (tubocurarine, metocurine, gallamine or pancuronium) after surgery. Neostigmine affects the body's chemicals, which are involved in communication between nerve impulses and muscle movements. Thereby, Tilstigmin Tablet treats associated muscle disorders by improving muscle strength.

How Tilstigmin Tablet Works

Tilstigmin Tablet contains 'Neostigmine.' It increases levels of a neurotransmitter called acetylcholine by stopping the excess cholinesterase activity (an enzyme required to break down acetylcholine) involved in communication between nerve impulses and muscle movements. Neurotransmitters are chemical messengers that transmit the message from one nerve cell to another nerve cell, muscle cell, or gland cell. Thus, Tilstigmin Tablet helps with proper muscle functioning and prevents muscle weakness.

Storage

Keep out of sight and reach of children.

What if I have taken an overdose of Tilstigmin Tablet

Take Tilstigmin Tablet only as prescribed by the physician. Avoid exceeding the recommended dose as it could lead to an overdose. Symptoms of overdose may include constipation, difficulty urination, decreased sexual ability, muscle weakness, enlarged pupils, and dry mouth. If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

Brief your medical history if you have any liver or kidney diseases, heart diseases (coronary artery disease, irregular heartbeat), asthma, stomach ulcer, fits, urination problems, Parkinson's disease, overactive thyroid, and irritability of vagus nerve (connects to the abdomen from the brain) that causes excess bowel contractions before starting Tilstigmin Tablet . Please consult your doctor if you are pregnant, planning to conceive, or are a breastfeeding mother. Avoid consuming alcohol with Tilstigmin Tablet to get the maximum benefits of the medicine and prevent the aggravation of the disease. Drive or operate machinery only when you are alert and focused during the course.

Drug-Drug Interactions

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NeostigmineTramadol
Severe

Drug-Drug Interactions

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NeostigmineTramadol
Severe
How does the drug interact with Tilstigmin Tablet:
Co-administration of tramadol with Tilstigmin Tablet can increase the effect of tramadol.

How to manage the interaction:
Taking Tilstigmin Tablet with tramadol together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience any symptoms such as confusion, hallucination, seizure, increased heart rate, blurred vision, tremors, incoordination, stomach cramps, nausea, vomiting, and diarrhea, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Maintain proper weight by following a healthy diet.
  • Avoid smoking and alcohol consumption.
  • Try to avoid stress by practising meditation or yoga.
  • Include fruits and vegetables in your diet as they contain antioxidants.
  • Eat warm meals rather than hot meals, as heat aggravates the disease.
  • Try sipping a cold drink while having hot or warm meals.
  • Avoid foods that require a lot of chewing, like tough meats.
  • Exercise regularly to keep your muscles strong
  • Limit foods with high cholesterol and saturated fats.
  • Cut down on sugar, salt and processed foods.
  • Drink plenty of water.

Habit Forming

No

Therapeutic Class

MUSCLE STIMULANTS AND CHOLINESTERASE INHIBITORS
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Alcohol

Caution

Avoid consuming alcohol while taking Tilstigmin Tablet to prevent any undesirable side effects.

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Pregnancy

Caution

There is limited information on how Tilstigmin Tablet affects pregnancy. Please consult your doctor before taking this medicine if you are pregnant or planning to conceive.

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Breast Feeding

Caution

It is not known if Neostigmine is excreted into breast milk. Please consult your doctor before taking Tilstigmin Tablet if you are a breastfeeding mother.

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Driving

Caution

Tilstigmin Tablet can make you feel dizzy and affect your ability to drive. It is advised not to drive or operate machinery while on treatment with Tilstigmin Tablet if you are not mentally alert and focused.

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Liver

Caution

Please consult your doctor before taking Tilstigmin Tablet if you have liver impairment/liver disease.

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Kidney

Caution

Please consult your doctor before taking Tilstigmin Tablet if you have kidney impairment/kidney disease.

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Children

Safe if prescribed

Tilstigmin Tablet is recommended in children below 12 years of age only when prescribed by the doctor. The dosage depends on the child’s age and weight.

FAQs

Tilstigmin Tablet belongs to a group of medicines called 'anticholinesterase agents/acetylcholinesterase inhibitors,' primarily used to treat myasthenia gravis. Tilstigmin Tablet is also used when the normal movements of the intestine are absent and to treat post-operative urinary retention.

Tilstigmin Tablet works by stopping the excessive cholinesterase activity (an enzyme necessary for the breakdown of a neurotransmitter called acetylcholine) involved in communication between nerve impulses and muscle movements. Thereby, Tilstigmin Tablet helps in proper muscle functioning and prevents muscle weakness.

Tilstigmin Tablet should be used with caution in the medical history of liver or kidney diseases, heart diseases (coronary artery disease, irregular heartbeat), chronic obstructive pulmonary disease, asthma, stomach ulcer, fits, urination problems, Parkinson's disease, overactive thyroid (hypothyroidism), and irritability of vagus nerve (connects to the abdomen from the brain) that causes excess bowel contractions. Please let your doctor know if you have any other medical problems before starting.

Do not stop taking Tilstigmin Tablet on your own. Please continue taking Tilstigmin Tablet for the prescribed period to treat your condition effectually. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Tilstigmin Tablet .

Take the missed dose as soon as possible. However, if it is time for the next dose, skip the missed dose and return to your regular dosing schedule. Do not double the dose.

Keep Tilstigmin Tablet in a cool, dry place away from direct sunlight. Dispose of unused medicine and keep it out of sight and reach from children and pets.

Country of origin

INDIA

Manufacturer/Marketer address

Tablets (India) Limited, “Jhaver Centre”, 72 Marshalls Road, Chennai 600 008.
Other Info - TIL0001

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 18, 2025 | 6:47 AM IST

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Reference

  1. https://www.medicines.org.uk/emc/files/pil.2849.pdf
  2. https://www.drugs.com/cons/neostigmine.html#side-effects
  3. https://www.drugs.com/cdi/neostigmine-tablets.html
  4. https://tmedweb.tulane.edu/pharmwiki/doku.php/neostigmine

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