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compositionComposition:FLUTAMIDE-250MG
prescription
Prescription Medicine
info
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Ticum 250mg Tablet is used to treat prostate cancer. It contains Flutamide which works by stopping the growth and spread of cancer. In some cases, this medicine may cause side effects such as vomiting, diarrhoea, loss of interest in sex, nausea, and enlargement of breasts. Inform the doctor if you are taking any other medication, or have any pre-existing medical conditions.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

FLUTAMIDE-250MG

Manufacturer/Marketer :

Neon Laboratories Ltd

Consume Type :

Oral

Expires on or after :

Dec-28

Return Policy :

Not Returnable

About Ticum 250mg Tablet

Ticum 250mg Tablet is primarily used to treat advanced prostate cancer that has spread to other parts of the body. It works as part of a combination hormone therapy to help slow down or halt the growth of cancer cells. This medication is typically prescribed to be used alongside other treatments to achieve the best possible management of the condition.

To ensure the medicine works effectively, it must be taken consistently at regular intervals throughout the day, exactly as directed by your healthcare provider. You can take this medication with or without food, making it easy to fit into your daily routine. Making positive changes, such as eating a balanced diet and staying physically active, can also support your overall well-being during treatment.

While taking Ticum 250mg Tablet, you may experience some common side effects like hot flashes, breast tenderness, or mild stomach upset. However, it is vital to watch for signs of serious complications, especially liver damage, which can sometimes occur. If you notice any unusual symptoms like yellowing of your eyes or skin, dark urine, or severe abdominal pain, contact your doctor immediately.

Do not take this if you have severe liver issues, as the medication can worsen liver damage. It is also not suitable for women, particularly those who are pregnant or breastfeeding, as it can cause harm to an unborn baby or infant. Always discuss your complete medical history with your doctor before starting this treatment.

This medicine can interact with other substances, including certain blood thinners, alcohol, and tobacco. Alcohol should be avoided because it can increase the strain on your liver. If you are an older adult, your doctor will closely monitor your health to ensure the medication is safe and effective for you.

Uses of Ticum 250mg Tablet

Here is the main condition where Ticum 250mg Tablet is used to slow cancer growth and improve disease control:

  • Prostate cancer: Ticum 250mg Tablet is used to treat advanced prostate cancer. It helps control the spread of the disease by blocking the male hormones that feed and promote the growth of cancer cells.

Key Benefits

Ticum 250mg Tablet offers several important benefits that help slow disease progression and improve quality of life during prostate cancer treatment:

  • Slows Cancer Progression: By blocking the action of male hormones, Ticum 250mg Tablet helps slow the growth and spread of prostate cancer cells.
  • Relieves Cancer-Related Symptoms: It may help reduce pain and discomfort associated with advanced prostate cancer, improving daily comfort.
  • Enhances Hormone Therapy: When used with other hormone treatments, Ticum 250mg Tablet provides more complete suppression of male hormone activity, improving overall treatment effectiveness.
  • Supports Daily Quality of Life: Better disease control can help patients remain more active and carry out daily activities with greater comfort.
Side effects of Ticum 250mg Tablet
  • Mild physical activity can increase blood flow and lessen pain from tense or irritated muscles.
  • Pain might be reduced with a supportive, properly fitting bra, particularly when exercising.
  • Limit or stay away from items that can cause breast pain, like spicy and caffeine-containing foods.
  • vitamin E medication which could ease breast pain and encourage rest.
  • Use hot or cold packs on your breasts to help alleviate discomfort.
  • Choose a supportive, well-fitting bra, preferably one that has been professionally fitted.
  • Practice relaxation techniques to manage stress and anxiety that may accompany severe breast pain.
  • Limit or avoid caffeine consumption.
  • Eat a low-fat diet and focus on foods rich in complex carbohydrates.
  • Rubbing evening primrose oil on your breasts may help balance fatty acids in the cells and reduce pain.
  • Keep track of when your breast pain occurs and any other symptoms to determine if the pain is regular or not.
  • Vitamin E supplements may help reduce pain for women who experience pain linked to their menstrual cycle.
  • Over-the-counter pain relievers like acetaminophen or ibuprofen can provide relief, but be sure to consult your doctor for the correct dosage, as prolonged use may cause side effects.
  • Minimize breast stimulation, including during intimacy.
  • Avoid tight or friction-causing clothing.
  • Wear breast pads to absorb discharge and prevent leakage.
  • Eat a balanced diet containing enough proteins, fibre, healthy fats, vegetables and fruits.
  • Get quality sleep for about 7-9 hours.
  • Try to manage stress with meditation or yoga.
  • Drink enough water.
  • Exercise regularly as it helps regulate appetite.
Here are the 7 step-by-step strategies to manage the side effect of "inability to sleep" caused by medication usage:
  • Prepare for a restful night's sleep: Develop a calming pre-sleep routine, like reading or meditation, to help your body relax and prepare for sleep.
  • Create a sleep-conducive Environment: Make bedroom a sleep haven by ensuring it is quiet, dark and calm.
  • Follow a Sleep Schedule: Go to bed and get up at the same time every day to help regulate your body's internal clock and increase sleep quality.
  • Try relaxing techniques like deep breathing, mindfulness meditation and any others.
  • Limit stimulating activities before bedtime: Avoid stimulating activities before bedtime to improve sleep quality.
  • Monitor Progress: Keep track of your sleep patterns to identify areas for improvement.
  • Consult a doctor if needed: If these steps don't improve your sleep, consult a doctor for further guidance and therapy.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.

Directions for Use

  • Ticum 250mg Tablet can be taken after meals to minimise potential stomach upset.
  • It is advised to take Ticum 250mg Tablet exactly as prescribed by your doctor, following the recommended dosage and duration to get optimal results.
  • Swallow Ticum 250mg Tablet as a whole with a glass of water.
  • Do not crush, chew, or break it.

How Ticum 250mg Tablet Works

Ticum 250mg Tablet contains flutamide, an antiandrogen medicine that helps treat advanced prostate cancer. Ticum 250mg Tablet works by blocking the action of male hormones, such as testosterone, on prostate cancer cells. It binds to the hormone receptors on these cells, preventing testosterone from attaching to them. Without these hormone signals, the cancer cells grow more slowly and are less able to multiply and spread. Together, these actions help slow the progression of prostate cancer and support the overall management of the disease.
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Alcohol

Unsafe

You are recommended to avoid alcohol consumption with Ticum 250mg Tablet as it may increase the risk of side effects such as dizziness, drowsiness or difficulty in concentrating.

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Pregnancy

Unsafe

Ticum 250mg Tablet is restricted to use in pregnancy. Ticum 250mg Tablet is not approved to use in females.

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Breast Feeding

Unsafe

Ticum 250mg Tablet is restricted to use in lactating mothers. Ticum 250mg Tablet is not approved to use in females.

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Driving

Caution

Ticum 250mg Tablet may make you dizzy so it is advised to avoid driving or doing any work that needs mental alertness.

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Liver

Caution

Ticum 250mg Tablet should be taken with caution in liver disease. The dose may be adjusted by the doctor according to the medical condition of the patient.

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Kidney

Caution

Ticum 250mg Tablet should be taken with caution in kidney disease. The dose may be adjusted by the doctor according to the medical condition of the patient.

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Children

Unsafe

Ticum 250mg Tablet is not recommended for children below 18 years as the safety and effectiveness were not established.

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Heart

Caution

Ticum 250mg Tablet should be taken with caution in patients with heart problems. Please inform your doctor about any existing heart problems before using Ticum 250mg Tablet.

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Geriatrics

Caution

Ticum 250mg Tablet should be taken with caution in geriatric patients. Dose adjustments may be needed.

What if I have taken an overdose of Ticum 250mg Tablet

If you take more than your prescribed dose, seek immediate medical attention or contact a poison control centre right away. Symptoms of an overdose may include severe stomach upset, breathing difficulties, or extreme fatigue.

Diet & Lifestyle Advise

  • Protect your liver: Avoid drinking alcohol while taking this medicine. Both alcohol and this medication can place stress on your liver, and combining them increases your risk of liver damage
  • Stay hydrated: If you experience diarrhoea as a side effect, drink plenty of water, clear broths, or electrolyte solutions to prevent dehydration.
  • Support your bones: Since hormone therapies can affect bone density over time, focus on a diet rich in calcium and Vitamin D. Ask your doctor if supplements are right for you.
  • Stay physically active: Engage in low-impact exercises, such as regular walking, to help manage fatigue, boost your mood, and maintain muscle and bone strength.
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Have a query?

How Soon It Starts Working

The time required for Ticum 250mg Tablet to start to work: Ticum 250mg Tablet ideally shows its action within 2 to 4 hours after administration. The time for which the effects of Ticum 250mg Tablet last: The effect of Ticum 250mg Tablet lasts for 6 to 8 hours.

What if you forget to take Ticum 250mg Tablet

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and resume your regular schedule. Do not take a double dose to make up for the missed one. Talk to your doctor or pharmacist if you frequently miss doses.

Storage

•Store Ticum 250mg Tablet tablets at room temperature between 20°C and 25°C (68°F to 77°F). •Keep the bottle tightly closed to protect the medication from light, moisture, and extreme heat.

Drug Warnings

  • Keep up with blood tests: You will need regular liver function tests while taking this medicine. Do not skip any scheduled laboratory visits.
  • Monitor urine colour: Pay close attention to the colour of your urine. Dark, amber, or tea-coloured urine can be an early warning sign of liver problems and should be reported to your doctor immediately.
  • Use effective birth control: If you are sexually active with a partner who can become pregnant, you must use highly effective barrier birth control (such as condoms) during treatment and for a period after stopping.
  • Protect your skin: This medicine may make your skin more sensitive to sunlight. Wear sunscreen, protective clothing, and sunglasses when outdoors.
  • Watch for severe diarrhoea: If you develop severe or persistent diarrhoea, stop taking the medicine and consult your doctor immediately to avoid dangerous dehydration.

Drug-Drug Interactions

verifiedApollotooltip

Here are the medicines that may interact with Ticum 250mg Tablet and require closer monitoring during treatment:

  • Blood thinners (like warfarin): Combining Ticum 250mg Tablet with blood thinners can increase the blood-thinning effect, which raises your risk of bleeding. Your doctor may need to adjust your blood thinner dose and monitor your blood clotting times more closely.
FlutamideZiprasidone
Critical
FlutamideCeritinib
Severe

Drug-Drug Interactions

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FlutamideZiprasidone
Critical
How does the drug interact with Ticum 250mg Tablet:
Using ziprasidone together with Ticum 250mg Tablet can increase the risk of an irregular heart rhythm

How to manage the interaction:
Taking Ziprasidone with Ticum 250mg Tablet is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
FlutamideCeritinib
Severe
How does the drug interact with Ticum 250mg Tablet:
Taking Ceritinib together with Ticum 250mg Tablet can increase the risk of an irregular heart rhythm and other side effects.

How to manage the interaction:
Taking Ceritinib with Ticum 250mg Tablet together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult the doctor immediately if you experience symptoms such as dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without consulting doctor.
FlutamideHaloperidol
Severe
How does the drug interact with Ticum 250mg Tablet:
Coadministration of Ticum 250mg Tablet and Haloperidol can increase the risk of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Co-administration of Ticum 250mg Tablet and Haloperidol can lead to an interaction, it can be taken if your doctor advises. Contact your doctor immediately if you experience any symptoms like sudden dizziness, lightheadedness, shortness of breath, heart palpitations, diarrhea, or vomiting. Do not discontinue any medications without consulting your doctor.
FlutamideBupivacaine
Severe
How does the drug interact with Ticum 250mg Tablet:
Taking Bupivacaine and Ticum 250mg Tablet may cause methemoglobinemia, (a condition in which the iron in the hemoglobin molecule -the red blood pigment is defective, making it unable to carry oxygen effectively to the tissues).

How to manage the interaction:
Although taking bupivacaine and Ticum 250mg Tablet together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience symptoms such as gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.
FlutamideMoxifloxacin
Severe
How does the drug interact with Ticum 250mg Tablet:
Using Moxifloxacin together with Ticum 250mg Tablet can increase the risk of an irregular heart rhythm.

How to manage the interaction:
There may be a possibility of interaction between Moxifloxacin and Ticum 250mg Tablet, but it can be taken if prescribed by a doctor. If you notice any of these symptoms an irregular heartbeat, vomiting, dizziness, difficulty breathing contact a doctor right away. Do not stop using any medications without a doctor's advice.
FlutamideSotalol
Severe
How does the drug interact with Ticum 250mg Tablet:
Using Ticum 250mg Tablet together with sotalol can increase the risk of an irregular heart rhythm. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
There may be a possibility of interaction between Sotalol and Ticum 250mg Tablet, but it can be taken if prescribed by a doctor. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
FlutamideLidocaine
Severe
How does the drug interact with Ticum 250mg Tablet:
Taking Ticum 250mg Tablet with Lidocaine can increase the risk of methemoglobinemia (blood disorder in which too little oxygen is delivered to your cells).

How to manage the interaction:
Although taking Lidocaine and Ticum 250mg Tablet together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, consult the doctor immediately if you develop gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, weakness, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not stop using any medications without consulting doctor.

Drug-Food Interactions

verifiedApollotooltip

Here is an important dietary consideration while taking Ticum 250mg Tablet:

  • Alcohol: Consuming alcohol while on this medication increases the risk of experiencing serious liver damage.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTINEOPLASTIC]

FAQs

Ticum 250mg Tablet is indicated in the treatment of prostate cancer.
Please consult with your doctor if you experience pain or burning sensation during urinating, frequent urination, trouble in stopping or starting urination, blood in urine and sudden erectile dysfunctioning. These may be the signs of prostate cancer.
Elderly persons are more sensitive to the negative effects of Ticum 250mg Tablet especially drowsiness, so your doctor may adjust the dosage according to your age and medical condition.
It is advised to tell your doctor if you have an allergy to any of the components present in Ticum 250mg Tablet or any other food or drinks. With it, also tell them if you have liver disease or increased liver enzymes. Ticum 250mg Tablet is not allowed to use in females.
In such a case, it is advised, you should drink a lot of noncaffeine liquids unless your doctor told you not to do so. you should eat more vegetables, fruits, vegetables and should avoid taking any type of laxatives(medicine to relieve constipation).
Yes, Ticum 250mg Tablet may lower testosterone levels. It is an anti-androgen medication that works by blocking the action of testosterone at its receptor sites, which can result in reduced levels of testosterone in the body. It is commonly used in the treatment of prostate cancer and certain other conditions related to hormone-sensitive cancers or conditions.
Ticum 250mg Tablet belongs to a class of medicines called anti-androgens (anti-testosterone). Testosterone, a natural hormone produced by the body, can stimulate the growth and spread of prostate cancer. Ticum 250mg Tablet works by blocking the action of testosterone, thereby helping to reduce the growth and spread of the cancer.
The side effects of Ticum 250mg Tablet include diarrhoea, nausea, vomiting, loss of interest in sexual ability, and enlargement of breasts. Consult the doctor if any of these side effects persist or worsen.
No, Ticum 250mg Tablet is not intended for use in women. It is specifically designed to block male hormones in prostate cancer treatment and can cause severe harm to an unborn baby. Talk to your doctor if you have questions about who should use this medicine.
Yes, in rare cases, this medication can cause severe liver damage. Your healthcare provider will schedule regular blood tests to monitor your liver function while you are taking it. Talk to your doctor immediately if you notice yellowing of your skin or eyes.
It is strongly advised to avoid alcohol while taking this medicine, as both substances are processed by the liver and combining them can significantly increase the risk of liver damage. Talk to your doctor or pharmacist for personalised safety advice.
Yes, if your partner is capable of becoming pregnant, you must use effective barrier birth control, such as condoms, during your treatment and for a time after stopping. This medicine can cause birth defects. Talk to your doctor for specific guidance.
Some medications, especially blood thinners like warfarin, can interact with Ticum 250mg Tablet and increase your risk of side effects. Always provide your healthcare team with a complete list of all medications, supplements, and vitamins you are taking, and talk to your doctor before starting any new treatment.

Disclaimer

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Country of origin

India
Other Info - TI10438
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