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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Themidrine 30mg Injection is used to treat low blood pressure. It contains Ephedrine which works by temporarily reducing the blood supply to small blood vessels. This medicine may sometimes cause side effects such as nausea, vomiting, headache, weakness, restlessness, and confusion. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Whats That

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Composition :

EPHEDRINE-30MG

Manufacturer/Marketer :

Themis Medicare Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

About Themidrine 30mg Injection

Themidrine 30mg Injection belongs to a class of medications called 'antihypotensives', used to relieve low blood pressure during spinal or epidural anaesthesia. Hypotension is a condition in which the blood flows through the blood vessels at lower than normal pressures.

Themidrine 30mg Injection contains 'Ephedrine', which works by raising blood pressure by temporarily reducing the blood supply to small blood vessels.

In some cases, you may experience confusion, nervousness, irritability, headache, nausea and vomiting. Most of these side effects of Themidrine 30mg Injection do not require medical attention and gradually resolve over time. However, if the side effects persist, please consult your doctor.

If you are allergic to Themidrine 30mg Injection or any other medicines, please tell your doctor. Please consult a doctor if you are pregnant or breastfeeding. Keep the doctor informed about your health condition and medications to rule out any side effects/interactions.

Uses of Themidrine 30mg Injection

Treatment of Hypotension (low blood pressure)

Directions for Use

• Follow your doctor's instructions on the dosage and timing of this medication.• Themidrine 30mg Injection will be administered by the doctor or nurse in a healthcare setting.• Do not self-administer.

Medicinal Benefits

Themidrine 30mg Injection belongs to a class of medications called 'antihypotensives', used to relieve low blood pressure during spinal or epidural anaesthesia. Themidrine 30mg Injection contains 'Ephedrine', which works by raising blood pressure by temporarily reducing the blood supply to small blood vessels.

How Themidrine 30mg Injection Works

Themidrine 30mg Injection contains 'Ephedrine', which works by raising blood pressure by temporarily reducing the blood supply to small blood vessels.

Storage

Keep Themidrine 30mg Injection out of reach and sight of children.
Side effects of Themidrine 30mg Injection
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.

What if I have taken an overdose of Themidrine 30mg Injection

Since Themidrine 30mg Injection is administered by a healthcare professional, an overdose is unlikely to occur. Overdose may cause nausea, vomiting, irregular heartbeat, high blood pressure, fever, respiratory depression, paranoid psychosis, convulsions, and coma. Seek medical attention if you experience these symptoms.

Drug Warnings

Inform the doctor if you have glaucoma, diabetes, high blood pressure, strokes, thyroid, or severe asthma. Themidrine 30mg Injection is not recommended for patients suffering from low blood pressure caused by hypovolaemia (low blood volume). Consult the doctor if you are pregnant or breastfeeding. Themidrine 30mg Injection is not recommended for children below 12 years. Let the doctor know if you are taking any other medications.

Drug-Drug Interactions

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Critical
EphedrineDihydroergotamine
Critical

Drug-Drug Interactions

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Critical
How does the drug interact with Themidrine 30mg Injection:
Taking Tranylcypromine with Themidrine 30mg Injection can increase the risk of high blood pressure.

How to manage the interaction:
Taking Tranylcypromine with Themidrine 30mg Injection is not recommended, it can be taken if prescribed by the doctor. However, if you experience sudden and severe headache, blurred vision, confusion, seizures, chest pain, nausea, or vomiting, sudden numbness or weakness (particularly on one side of the body), trouble speaking, fever, sweating, lightheadedness, and/or fainting, consult the doctor. Do not discontinue any medications without a doctor's advice.
EphedrineDihydroergotamine
Critical
How does the drug interact with Themidrine 30mg Injection:
Co-administration of Dihydroergotamine may increase the high blood pressure and blood vessel narrowing effects of Themidrine 30mg Injection.

How to manage the interaction:
Combining Themidrine 30mg Injection with Dihydroergotamine is not recommended as it can result in an interaction, but it can be taken if a doctor has prescribed it. However, if you experience symptoms like severe stomach pain, nausea, vomiting, numbness or tingling, muscle pain or weakness, blue or purple discoloration of fingers or toes, pale or cold skin, chest pain or tightness, severe or throbbing headache, irregular heartbeat, breathing difficulty, blurred vision, confusion, slurred speech, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.
EphedrinePhenelzine
Critical
How does the drug interact with Themidrine 30mg Injection:
Co-administration of Phenelzine with Themidrine 30mg Injection can increase the risk of high blood pressure.

How to manage the interaction:
Although taking Themidrine 30mg Injection and Phenelzine together is not recommended as it can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience symptoms like very high blood pressure, a sudden and severe headache, blurry vision, confusion, seizures(fits), chest pain, nausea, vomiting, sudden numbness or weakness, trouble speaking, fever, sweating, feeling dizzy, or fainting, consult the doctor. It is important to maintain your blood pressure. Do not discontinue any medications without consulting a doctor.
EphedrineProcarbazine
Critical
How does the drug interact with Themidrine 30mg Injection:
Taking Themidrine 30mg Injection and Procarbazine together can increase the risk of high blood pressure.

How to manage the interaction:
Taking Themidrine 30mg Injection and Procarbazine together is not recommended as it can result in an interaction, it can be taken if a doctor has prescribed it. However, if you develop a sudden, severe headache, blurred vision, disorientation, seizures, chest pain, nausea, or vomiting, sudden numbness or weakness (particularly on one side of the body), difficulty speaking, fever, sweating, lightheadedness, or fainting, you should consult the doctor. Do not discontinue any medications without a doctor's advice.
EphedrineSibutramine
Critical
How does the drug interact with Themidrine 30mg Injection:
Co-administration of Sibutramine can intensify the effects of Themidrine 30mg Injection, and it may also have undesirable effects like anxiety, nervousness, restlessness, and racing thoughts.

How to manage the interaction:
Taking Themidrine 30mg Injection with Sibutramine is not recommended, it can be taken if your doctor has advised it. However, if you experience hallucinations, seizures, abnormal blood pressure changes, a fast heart rate, fever, increased sweating, blurred vision, muscle pain or stiffness, tremors, pain in the stomach, nausea, vomiting, and diarrhoea, consult the doctor. Do not discontinue any medications without a doctor's advice.
Critical
How does the drug interact with Themidrine 30mg Injection:
When Themidrine 30mg Injection and Methylene blue are combined, there is an increase in the risk or severity of high blood pressure.

How to manage the interaction:
Taking Themidrine 30mg Injection and Methylene blue is not recommended as it can result in an interaction, it can be taken if a doctor has prescribed it. However, if you develop a sudden, severe headache, blurred vision, disorientation, seizures, chest pain, nausea, or vomiting, sudden numbness or weakness (particularly on one side of the body), difficulty speaking, fever, sweating, lightheadedness, or fainting, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.
EphedrineAmitriptyline
Severe
How does the drug interact with Themidrine 30mg Injection:
Co-administration of Amitriptyline with Themidrine 30mg Injection can increase the levels of Themidrine 30mg Injection which may lead to side effects.

How to manage the interaction:
Although taking Amitriptyline and Themidrine 30mg Injection simultaneously can interact, you can do so if your doctor has prescribed it. Regular monitoring of blood pressure is advised. Do not discontinue any medications without a doctor's advice.
EphedrineImipramine
Severe
How does the drug interact with Themidrine 30mg Injection:
Co-administration of Themidrine 30mg Injection and Imipramine together may increase the risk of side effects.

How to manage the interaction:
Although taking Themidrine 30mg Injection and Imipramine together can cause an interaction, it can be taken if a doctor has suggested it. Maintaining blood pressure is advised. Do not stop using any medications without a doctor's advice.
EphedrineFurazolidone
Severe
How does the drug interact with Themidrine 30mg Injection:
Co-administration of Furazolidone with Themidrine 30mg Injection can increase the risk of high blood pressure.

How to manage the interaction:
Taking Themidrine 30mg Injection with Furazolidone can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience symptoms like a sudden and severe headache, blurred vision, confusion, seizures, chest pain, nausea, or vomiting, sudden numbness or weakness (particularly on one side of the body), trouble speaking, fever, sweating, lightheadedness, fainting, consult the doctor right away. It is advised to use Themidrine 30mg Injection only after stopping furazolidone for at least 14 days. Do not stop using any medications without a doctor's advice.
EphedrineErgotamine
Severe
How does the drug interact with Themidrine 30mg Injection:
Co-administration of Themidrine 30mg Injection's blood pressure and blood vessel narrowing effects may be increased by Ergotamine.

How to manage the interaction:
There may be a possibility of interaction between Themidrine 30mg Injection and Ergotamine, but it can be taken if prescribed by a doctor. If you notice any of these symptoms - like an irregular heartbeat, breathing difficulty, nausea, vomiting, numbness or tingling, muscle pain or weakness, blue or purple discolouration of the fingers or toes, pale or cold skin, chest pain or tightness, impaired vision, confusion, difficulty speaking, stomach pain, consult the doctor. Do not discontinue any medications without consulting the doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat small meals more frequently.

  • Drink plenty of fluids to stay hydrated as dehydration may reduce blood volume resulting in low blood pressure.

  • Include vitamin B12 rich foods such as animal meats, eggs, fortified cereals, and nutritional yeast.

  • Eat foods rich in folates such as beans, asparagus, lentils, leafy greens, citrus fruits, liver, and eggs.

  • Try to eat smoked fish, canned soup, pickled items, cottage cheese, and olives as salty foods can also increase blood pressure.

  • Take frequent breaks if you exercise outdoors in extreme heat.

  • Avoid spending a long time in hot tubs, steam rooms, and saunas to prevent dehydration.

Habit Forming

No

Therapeutic Class

ANTIHYPOTENSIVES
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Alcohol

Caution

The interaction of Themidrine 30mg Injection with alcohol is unknown. Please consult a doctor before consuming alcohol while using Themidrine 30mg Injection.

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Pregnancy

Caution

Themidrine 30mg Injection is a category C pregnancy drug and is given to pregnant women only if the doctor thinks the benefits outweigh the risks. Please consult a doctor if you are pregnant.

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Breast Feeding

Caution

Themidrine 30mg Injection is given to breastfeeding women only if the doctor thinks benefits are greater than risks. Please consult a doctor if you are breastfeeding.

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Driving

Caution

Drive only if you are alert after taking Themidrine 30mg Injection. However, Themidrine 30mg Injection is generally given for hospitalised patients.

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Liver

Caution

Themidrine 30mg Injection should be given with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Themidrine 30mg Injection should be given with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Unsafe

Themidrine 30mg Injection is not recommended for children as the safety and effectiveness were not established.

Have a query?

FAQs

Themidrine 30mg Injection is used to relieve low blood pressure during spinal or epidural anaesthesia.

Themidrine 30mg Injection works by raising blood pressure by temporarily reducing the blood supply to small blood vessels.

Themidrine 30mg Injection should be used with caution in patients suffering from heart rhythm disorders as it may increase the risk of severe adverse effects. Therefore, inform your doctor if you have any heart problems before taking Themidrine 30mg Injection so that the dose may be adjusted appropriately or an alternate medicine may be prescribed.

You are recommended not to take Themidrine 30mg Injection if you have diabetes as it may increase blood sugar levels. Therefore, it is advised to inform your doctor if you have diabetes before taking Themidrine 30mg Injection.

Themidrine 30mg Injection may cause a headache as a temporary side effect. However, if the condition persists or worsens, please consult a doctor.

Country of origin

India
Other Info - TH15045

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