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  3. TENTIDE 300MG TABLET

TENTIDE 300MG TABLET, Pack of 1 TABLET
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Written By Veda Maddala , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
TENTIDE 300MG TABLET is used to treat HIV infection and chronic hepatitis B. It contains Tenofovir disoproxil, which works by interfering with the normal working of enzymes (reverse transcriptase in HIV and DNA polymerase in HBV) that are essential for the production of viruses. It may cause common side effects such as diarrhoea, vomiting, nausea, bloating, flatulence, weakness, dizziness, headache, abdominal pain, and fatigue. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Composition :

TENOFOVIR DISOPROXIL-300MG

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About TENTIDE 300MG TABLET

TENTIDE 300MG TABLET belongs to the group of medications called ‘antiretroviral drugs’ used to treat HIV infection and chronic hepatitis B. Human immunodeficiency virus (HIV) is a sexually transmitted infection that, over time, leads to acquired immunodeficiency syndrome (AIDS). Chronic hepatitis B is a long-term viral infection caused by the hepatitis B virus.

TENTIDE 300MG TABLET contains ‘Tenofovir disoproxil’, a ‘nucleotide reverse transcriptase inhibitor’ that works by interfering with the normal working of enzymes (reverse transcriptase in HIV and DNA polymerase in HBV) that are essential for the production of viruses. It effectively reduces the symptoms associated with HIV and chronic hepatitis B infection.

You should use this medicine as prescribed by your doctor. The common side-effects of TENTIDE 300MG TABLET are diarrhoea, being sick (vomiting), feeling sick (nausea), bloating, flatulence, weakness, dizziness, headache, abdominal pain, and fatigue. However, seek medical attention if the side effects persist or worsen.

Do not take TENTIDE 300MG TABLET if you are allergic to any of its contents. Patients should take necessary precautions to avoid infecting others. It should be used cautiously in patients with severe liver and kidney diseases. Consult a doctor immediately if you develop any new signs of infection while using this medicine. Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding.

Uses of TENTIDE 300MG TABLET

Treatment of HIV, Chronic hepatitis B.

Directions for Use

• TENTIDE 300MG TABLET can be taken with or without food as advised by your doctor.• It is usually taken once a day or as directed by the doctor.• Swallow TENTIDE 300MG TABLET as a whole with a glass of water.• Do not chew, crush or break it.

Medicinal Benefits

TENTIDE 300MG TABLET contains ‘Tenofovir disoproxil’, which is an antiretroviral agent. It can effectively cause viral suppression in HIV and chronic hepatitis B. It acts on the enzymes that are essential for the replication of the virus. The enzyme essential for HIV replication is reverse transcriptase, and the enzyme for hepatitis B is DNA polymerase. TENTIDE 300MG TABLET blocks these enzymes and decreases the viral load in the blood.

How TENTIDE 300MG TABLET Works

TENTIDE 300MG TABLET contains ‘Tenofovir disoproxil’, a ‘nucleotide reverse transcriptase inhibitor’ that works by interfering with the normal working of enzymes (reverse transcriptase in HIV and DNA polymerase in HBV) that are essential for the production of viruses. It effectively reduces the symptoms associated with HIV and chronic hepatitis B infection.

Storage

Keep this medicine out of sight and reach of children.
Side effects of Tentide 300mg Tablet
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Apply a hot/cold pack to the affected area.
  • Doing gentle exercises can help cope with pain by stretching muscles.
  • Get enough sleep. It helps enhance mood and lower pain sensitivity.
  • Avoid alcohol, smoking and tobacco as they can increase pain.
  • Follow a well-balanced meal.
  • Meditation and massages may also help with pain.
Here's a comprehensive approach to managing medication-triggered fever:
  • Inform your doctor immediately if you experience a fever after starting a new medication.
  • Your doctor may adjust your medication regimen or dosage as needed to minimize fever symptoms.
  • Monitor your body temperature to monitor fever progression.
  • Drink plenty of fluids, such as water or electrolyte-rich beverages, to help your body regulate temperature.
  • Get plenty of rest and engage in relaxation techniques, such as deep breathing or meditation, to help manage fever symptoms.
  • Under the guidance of your doctor, consider taking medication, such as acetaminophen or ibuprofen, to help reduce fever.
  • If your fever is extremely high (over 103°F), or if you experience severe symptoms such as confusion, seizures, or difficulty breathing, seek immediate medical attention.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Managing back pain as a side effect of medication requires a combination of self-care techniques, lifestyle modifications, and medical interventions. Here are the steps:
  • Talk to your doctor about your back pain and potential medication substitutes or dose changes.
  • Try yoga or Pilates and other mild stretching exercises to increase flexibility and strengthen your back muscles.
  • To lessen the tension on your back, sit and stand upright and maintain proper posture.
  • To alleviate discomfort and minimize inflammation, apply heat or cold packs to the afflicted area.
  • Under your doctor's supervision, think about taking over-the-counter painkillers like acetaminophen or ibuprofen.
  • Make ergonomic adjustments to your workspace and daily activities to reduce strain on your back.
  • To handle tension that could make back pain worse, try stress-reduction methods like deep breathing or meditation.
  • Use pillows and a supportive mattress to keep your spine in the right posture as you sleep.
  • Back discomfort can worsen by bending, twisting, and heavy lifting.
  • Speak with a physical therapist to create a customized training regimen to increase back strength and flexibility.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.

What if I have taken an overdose of TENTIDE 300MG TABLET

Do not take more than the prescribed dose of TENTIDE 300MG TABLET as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

Do not take TENTIDE 300MG TABLET if you are allergic to ‘tenofovir disoproxil’ or any other contents present in it. It is contraindicated in adolescents with kidney failure. When this medicine is used in combination therapy for HIV, there is a risk of osteonecrosis (bone tissue death). There is a severe risk of fatal complications in patients with severe liver diseases, including chronic hepatitis B or C. Consult a doctor immediately if you develop any new signs of infection while using this medicine, as there is a chance of opportunistic infections (infection seen in patients with a weak immune system). Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding.

Drug-Drug Interactions

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Tenofovir disoproxilStreptozocin
Critical
Tenofovir disoproxilDidanosine
Critical

Drug-Drug Interactions

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Tenofovir disoproxilStreptozocin
Critical
How does the drug interact with Tentide 300mg Tablet:
Combining Tentide 300mg Tablet and Streptozocin can increase the risk of kidney problems.

How to manage the interaction:
Taking Tentide 300mg Tablet with Streptozocin is not recommended, as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not stop using any medications without talking to your doctor.
Tenofovir disoproxilDidanosine
Critical
How does the drug interact with Tentide 300mg Tablet:
Coadministration of Didanosine with Tentide 300mg Tablet can increase the levels and risk of Didanosine side effects.

How to manage the interaction:
Taking Didanosine with Tentide 300mg Tablet is not recommended, please consult your doctor before taking it. It can be taken if your doctor prescribes it. However, if you experience severe headaches, confusion, weakness, trouble walking, muscle pain, or high fever, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
Tenofovir disoproxilDeferoxamine
Severe
How does the drug interact with Tentide 300mg Tablet:
Coadministration of Deferoxamine with Tentide 300mg Tablet can increase the risk of kidney problems.

How to manage the interaction:
Taking Deferoxamine and Tentide 300mg Tablet together can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
Tenofovir disoproxilPhenytoin
Severe
How does the drug interact with Tentide 300mg Tablet:
Coadministration of Phenytoin and Tentide 300mg Tablet can reduce the levels of Tentide 300mg Tablet, which can lead to low treatment outcomes.

How to manage the interaction:
Taking Tentide 300mg Tablet and Phenytoin together can result in an interaction, but it can be taken if your doctor has advised it. Do not discontinue any medications without consulting a doctor.
Tenofovir disoproxilLithium
Severe
How does the drug interact with Tentide 300mg Tablet:
Co-administration of Lithium carbonate with Tentide 300mg Tablet can increase the risk of developing kidney problems.

How to manage the interaction:
Although there is a possible interaction between Tentide 300mg Tablet and Lithium, you can take these medicines when prescribed by your doctor. Consult the doctor immediately if you experience symptoms such as vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, shortness of breath, muscle cramps, or weakness. Do not discontinue any medications without consulting a doctor.
Tenofovir disoproxilPolymyxin b
Severe
How does the drug interact with Tentide 300mg Tablet:
Coadministration of Tentide 300mg Tablet with Polymyxin B can increase the risk of side effects.

How to manage the interaction:
Taking Tentide 300mg Tablet with Polymyxin B together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience nausea, vomiting, a decrease in hunger, increased or decreased urine, weight gain or loss that occurs suddenly, swelling, difficulty breathing, bone pain, muscle pain, fatigue, weakness, dizziness, confusion, and irregular heartbeat, consult a doctor immediately. Do not stop using any medications without consulting a doctor.
Tenofovir disoproxilPiroxicam
Severe
How does the drug interact with Tentide 300mg Tablet:
Coadministration of Piroxicam and Tentide 300mg Tablet can increase the risk of kidney damage.

How to manage the interaction:
Co-administration of Tentide 300mg Tablet with Piroxicam can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience nausea, vomiting, decreased appetite, increased or decreased urine, weight gain or loss that occurs suddenly, swelling, difficulty breathing, muscle pain, dizziness, and irregular heartbeat, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
Tenofovir disoproxilKetorolac
Severe
How does the drug interact with Tentide 300mg Tablet:
Coadministration of Ketorolac with Tentide 300mg Tablet may increase the risk of developing kidney problems.

How to manage the interaction:
Although taking Ketorolac and Tentide 300mg Tablet together can possibly result in an interaction, it can be taken when your doctor has prescribed it. However, if you experience symptoms like nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, shortness of breath, fatigue, dizziness, confusion, and irregular heartbeat, consult a doctor. Do not discontinue any medications without consulting a doctor.
Tenofovir disoproxilKetoconazole
Severe
How does the drug interact with Tentide 300mg Tablet:
Coadministration of Ketoconazole and Tentide 300mg Tablet may increase the risk of developing liver damage.

How to manage the interaction:
Although taking Ketoconazole and Tentide 300mg Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you have any symptoms like fever, chills, joint pain or swelling, unusual bleeding, fatigue, vomiting, abdominal pain, dark urine, light stools, and/or yellowing of the skin or eyes, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
Tenofovir disoproxilIopromide
Severe
How does the drug interact with Tentide 300mg Tablet:
Coadministration of Iopromide and Tentide 300mg Tablet can increase the risk of kidney problems.

How to manage the interaction:
Taking Iopromide and Tentide 300mg Tablet together can lead to an interaction, but it can be taken if advised by your doctor. However, if you experience any symptoms like nausea, vomiting, increased or decreased urination, sudden weight gain or weight loss, swelling, shortness of breath, weakness, and irregular heart rhythm, contact your doctor immediately. You should drink plenty of fluids to keep yourself hydrated, help flush the contrast agent out of your kidneys, and do not discontinue any medications without consulting your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a diet with fresh fruits and vegetables.
  • Option for lean meat such as skinless chicken and fish. Limit processed and high-sugar foods.
  • Avoid acidic foods such as tomatoes, lemons, and oranges.
  • Limit alcohol intake and quit smoking.
  • Exercise regularly as it promotes both physical and mental health.
  • Take the necessary precautions to avoid the spread of infection to other people.

Habit Forming

No

Therapeutic Class

ANTIRETROVIRAL AGENTS

TENTIDE 300MG TABLET Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Caution

Consuming alcohol while using TENTIDE 300MG TABLET may worsen the condition.

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Pregnancy

Caution

TENTIDE 300MG TABLET is a category B medicine. It should be used with caution in pregnant women.

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Breast Feeding

Caution

In the case of chronic hepatitis B, TENTIDE 300MG TABLET should be used in breastfeeding mothers only if clinically needed. Avoid breastfeeding if you have HIV.

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Driving

Caution

TENTIDE 300MG TABLET may cause dizziness. So, avoid driving if you feel dizzy.

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Liver

Caution

TENTIDE 300MG TABLET should be used with caution if you have liver disease. Dose adjustments may be necessary.

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Kidney

Caution

TENTIDE 300MG TABLET should not be used in adolescents with kidney failure. In other people with severe kidney diseases, TENTIDE 300MG TABLET is prescribed only if clinically needed.

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Children

Caution

TENTIDE 300MG TABLET should be used with caution in children below 12 years of age.

Have a query?

FAQs

TENTIDE 300MG TABLET is used to treat HIV infection and chronic hepatitis B.

TENTIDE 300MG TABLET works by blocking the action of enzymes that are essential for viral replication.

TENTIDE 300MG TABLET does not affect fertility. However, consult your doctor immediately if you develop any side effects while using TENTIDE 300MG TABLET.

TENTIDE 300MG TABLET should be taken as prescribed by your doctor. Abrupt stopping of this medicine may lead to resistance to other medications making the infection difficult to treat.

The chances of not having an HIV infection after taking the TENTIDE 300MG TABLET are high, when used correctly, and consult a doctor to confirm whether the further precautions are needed.

TENTIDE 300MG TABLET is used to treat HIV-1 virus so you can take the TENTIDE 300MG TABLET but if you are suffering with tuberculosis then you should consult the doctor. Inform about your medical conditions and take TENTIDE 300MG TABLET only if it is advised by your physician. Do not self-medicate.

In case of HIV-1 infection, TENTIDE 300MG TABLET may reduce the risk of passing the virus to others, but the chances of infecting others can still be there. In case of HBV infection, TENTIDE 300MG TABLET has not proven to reduce the risk of passing the virus to others.

TENTIDE 300MG TABLET is safe if used as advised by the doctor. It should be avoided by children under age of 12, but can be used by children of age group between 12-18 years.

Take TENTIDE 300MG TABLET preferably with food or as advised by the doctor. Swallow it with a glass of water. Do not crush or chew it.

You should take the TENTIDE 300MG TABLET for as long as it is prescribed by the doctor. Do not stop using it without the notice of the doctor until the course is completed as it may worsen your condition.

If you vomit within 1 hour of taking TENTIDE 300MG TABLET, then take the other tablet. If you vomit more than 1 hour after taking TENTIDE 300MG TABLET, then do not take another dose.

It is important not to miss a dose of TENTIDE 300MG TABLET. If you miss a dose, you should work out how long since you should have taken it, do not take a double dose to make up for a forgotten tablet. Wait and take next dose at the regular time.

Country of origin

India

Manufacturer/Marketer address

SUN HOUSE, CTS No. 201 B/1, Western Express Highway, Goregaon (E), Mumbai 400063
Other Info - TEN0146

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Author Details

Veda MaddalaDoctor badge

Written By

Veda Maddala

M Pharmacy

Bayyarapu Mahesh KumarDoctor badge

Reviewed By

Bayyarapu Mahesh Kumar

M Pharmacy

Last Updated

Jul 18, 2025 | 6:40 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.medicines.org.uk/emc/files/pil.8138.pdf

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