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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Tenfoclear 300 Tablet is used to treat HIV and chronic hepatitis B infection. It contains Tenofovir disoproxil fumarate which works by preventing the development of the virus in the human body. In some cases, this medicine may cause side effects such as diarrhoea, rash, nausea, pain, weakness, and stomach pain. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Manufacturer/Marketer :

Abbott India Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Tenfoclear 300 Tablet

Tenfoclear 300 Tablet belongs to the group of medicines known as ‘antiviral medicines’ used to control HIV infection and chronic hepatitis B infection. Human immunodeficiency virus (HIV) is a sexually transmitted infection that over time leads to acquired immunodeficiency syndrome (AIDS). Chronic hepatitis B is a long-term viral infection caused by the hepatitis B virus.

Tenfoclear 300 Tablet contains ‘Tenofovir disoproxil fumarate’ which is an antiviral/HIV medicine and works by prevents the development of the virus in human cells. This prevents the virus from producing new viruses and cleans up your infection. It can effectively reduce the symptoms associated with HIV and chronic hepatitis B infection.

Take Tenfoclear 300 Tablet as prescribed by your doctor. Your doctor will recommend how often you take Tenfoclear 300 Tablet based on your medical condition. Some people may experience diarrhea, rash, nausea, pain, weakness, and stomach pain. Most of these side effects of Tenfoclear 300 Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Tenfoclear 300 Tablet should not be taken if you are allergic to Tenfoclear 300 Tablet or any other contents present in it. Patients should take necessary precautions to avoid infecting others. This medicine should not be given to adolescents with a history of kidney failure. If you have liver disease including hepatitis B or C, then you should not take this Tenfoclear 300 Tablet . Inform your doctor if you are pregnant, planning to become pregnant, and breastfeeding. Avoid drinking alcohol as it may increase the risk of side effects. It is advisable to avoid driving while using Tenfoclear 300 Tablet as Tenfoclear 300 Tablet may cause dizziness that may affect the ability to drive or use machines. Tenfoclear 300 Tablet should not be used for children less than 12 years of age.

Uses of Tenfoclear 300 Tablet

Treatment of HIV infections, Chronic hepatitis.

Directions for Use

• Tenfoclear 300 Tablet can be taken with or without food as advised by your doctor.• Follow your doctor's instructions on the dosage and timing of this medication.• Swallow Tenfoclear 300 Tablet as a whole with a glass of water.• Do not crush, break, or chew it.

Medicinal Benefits

Tenfoclear 300 Tablet belongs to the group of medications called ‘antiretroviral drugs’ used to control HIV infection and chronic hepatitis B. Tenfoclear 300 Tablet decreases the amount of HIV in your body. Therefore, your immune system may work better. This reduces your chance of getting complications of HIV like new infections, cancer and enhances your quality of life. Tenfoclear 300 Tablet works by prevents the development of viruses in human cells. This prevents the virus from producing new viruses and cleans up your infection. It can effectively reduce the symptoms associated with HIV and chronic hepatitis B infection.

How Tenfoclear 300 Tablet Works

Tenfoclear 300 Tablet contains ‘Tenofovir disoproxil fumarate’ which is an antiviral/HIV medicine and works by prevents the development of the virus in human cells. This prevents the virus from producing new viruses and cleans up your infection. It can effectively reduce the symptoms associated with HIV and chronic hepatitis B infection.

Storage

Keep this medicine out of the sight and reach of children.
Side effects of Tenfoclear 300 Tablet
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
  • Apply a hot/cold pack to the affected area.
  • Doing gentle exercises can help cope with pain by stretching muscles.
  • Get enough sleep. It helps enhance mood and lower pain sensitivity.
  • Avoid alcohol, smoking and tobacco as they can increase pain.
  • Follow a well-balanced meal.
  • Meditation and massages may also help with pain.
Managing depression as a side effect of medication: a comprehensive guide.
  • Remember, managing depression as a side effect of medication requires patience, persistence, and collaboration with your healthcare team.
  • Tell your doctor about your depression symptoms to adjust medication.
  • Consult a therapist or counsel for emotional support.
  • Engage in regular exercise to release endorphins (neurotransmitters).
  • Practice stress-reducing techniques like meditation and deep breathing.
  • Build a support network of friends, family, and support groups.
  • Establish a consistent sleep schedule.
  • Eat a nutritious diet rich in fruits, vegetables, and whole grains.
  • Limit or avoid alcohol and recreational substances.
  • Keep a mood journal to track symptoms and progress.
Here are the step-by-step strategies to manage the side effects of " Muscle Pain" caused by medication usage:
  • Report to Your Doctor: Inform your doctor about the muscle pain, as they may need to adjust your medication.
  • Stretch Regularly: Gentle stretching can help relieve muscle pain and stiffness.
  • Stay Hydrated: Adequate water intake supports muscle health by removing harmful substances and maintaining proper muscle function.
  • Warm or Cold Compresses: Apply cold or warm compresses to the affected area to reduce pain and inflammation.
  • Rest and Relaxation: Adequate rest helps alleviate muscle strain, while relaxation techniques like deep breathing and meditation can soothe muscle tightness, calm the mind, and promote relief from discomfort.
  • Gentle Exercise: Participate in low-impact activities, such as yoga or short walks, to improve flexibility, reduce muscle tension, and alleviate discomfort.
  • Consult a physician: If your symptoms don't improve or get worse, go to the doctor for help and guidance.
  • If you have excess nerve pain and numbness, soak in Epsom salt and warm water. This can help ease the pain and associated discomfort.
  • Use compression socks and make sure to rest for a while to get relief from pain.
  • Avoid smoking and intake of alcohol or fluids that aggravate the pain.
  • Massage your feet or affected area often to get relief from pain. Take the medication prescribed by your doctor without fail.

What if I have taken an overdose of Tenfoclear 300 Tablet

Avoid exceeding the recommended dose as it might cause an overdose. Seek immediate medical attention if you experience any unusual symptoms.

Drug Warnings

Tenfoclear 300 Tablet should not be taken if you are allergic to Tenfoclear 300 Tablet or any other contents present in it. Tenfoclear 300 Tablet should not be taken in the conditions like liver disease, bone problems kidney disease. This medicine should not be given to adolescents with a history of kidney failure. Tenfoclear 300 Tablet does not decrease the chances of passing infections to others. Inform your doctor before taking Tenfoclear 300 Tablet if you observe any symptoms of infection or other symptoms like weakness beginning in the hands and feet, muscle weakness and moving up towards the trunk of the body, palpitations (racing or skipping heartbeat), hyperactivity and tremor. Patients should take necessary precautions to avoid infecting others. Inform your doctor if you are pregnant, planning to become pregnant and breastfeeding. Inform your doctor before using Tenfoclear 300 Tablet if you are older than 65 years of age. Avoid drinking alcohol as it may increase the risk of side effects. It is advisable to you do not drive while using Tenfoclear 300 Tablet as Tenfoclear 300 Tablet may cause dizziness that may affect the ability to drive or use machines. Tenfoclear 300 Tablet should not be used for children less than 12 years of age.

Drug-Drug Interactions

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Critical
Critical

Drug-Drug Interactions

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Critical
How does the drug interact with Tenfoclear 300 Tablet:
Combining Tenfoclear 300 Tablet and Streptozocin can increase the risk of kidney problems.

How to manage the interaction:
Taking Tenfoclear 300 Tablet with Streptozocin is not recommended, as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not stop using any medications without talking to your doctor.
Critical
How does the drug interact with Tenfoclear 300 Tablet:
Coadministration of Didanosine with Tenfoclear 300 Tablet can increase the levels and risk of Didanosine side effects.

How to manage the interaction:
Taking Didanosine with Tenfoclear 300 Tablet is not recommended, please consult your doctor before taking it. It can be taken if your doctor prescribes it. However, if you experience severe headaches, confusion, weakness, trouble walking, muscle pain, or high fever, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Tenfoclear 300 Tablet:
Coadministration of Tenfoclear 300 Tablet with Cyclophosphamide may increase the risk of developing kidney problems.

How to manage the interaction:
Although there is a possible interaction, Cyclophosphamide can be taken with Tenfoclear 300 Tablet if prescribed by the doctor. Consult the doctor if you experience signs and symptoms of kidney damage such as nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not stop using any medication without consulting a doctor.
How does the drug interact with Tenfoclear 300 Tablet:
Coadministration of Deferoxamine with Tenfoclear 300 Tablet can increase the risk of kidney problems.

How to manage the interaction:
Taking Deferoxamine and Tenfoclear 300 Tablet together can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Tenfoclear 300 Tablet:
Combining Teriflunomide and Tenfoclear 300 Tablet can increase the risk of liver problems.

How to manage the interaction:
Taking Teriflunomide and Tenfoclear 300 Tablet together can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any symptoms like fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark-coloured urine, light-coloured stools, and/or yellowing of the skin or eyes, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
How does the drug interact with Tenfoclear 300 Tablet:
Coadministration of Carbamazepine and Tenfoclear 300 Tablet together may reduce the treatment outcomes of Tenfoclear 300 Tablet.

How to manage the interaction:
Although taking carbamazepine and Tenfoclear 300 Tablet together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Tenfoclear 300 Tablet:
Coadministration of Mefenamic acid with Tenfoclear 300 Tablet can show additive effect and increase the risk or severity of kidney problems.

How to manage the interaction:
Taking Mefenamic acid with Tenfoclear 300 Tablet together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any unusual bleeding or bruising, dizziness, red or black tarry stools, vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Tenfoclear 300 Tablet:
Coadministration of Sulfasalazine and Tenfoclear 300 Tablet can increase the risk of kidney problems.

How to manage the interaction:
Taking Sulfasalazine and Tenfoclear 300 Tablet together can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any symptoms like nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Tenfoclear 300 Tablet:
Coadministration of Tenfoclear 300 Tablet with Methotrexate may increase the levels and side effects of Tenfoclear 300 Tablet.

How to manage the interaction:
Although there is a possible interaction between Tenfoclear 300 Tablet and methotrexate, you can take these medicines when prescribed by your doctor. However, if you experience any symptoms such as vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, breathing difficulty, or dizziness, consult your doctor. Do not stop using any medications without consulting a doctor.
How does the drug interact with Tenfoclear 300 Tablet:
Coadministration of Tenfoclear 300 Tablet with Polymyxin B can increase the risk of side effects.

How to manage the interaction:
Taking Tenfoclear 300 Tablet with Polymyxin B together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience nausea, vomiting, a decrease in hunger, increased or decreased urine, weight gain or loss that occurs suddenly, swelling, difficulty breathing, bone pain, muscle pain, fatigue, weakness, dizziness, confusion, and irregular heartbeat, consult a doctor immediately. Do not stop using any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a diet with fresh fruits and vegetables.
  • Option for lean meat such as skinless chicken and fish. Limit processed and high-sugar foods.
  • Avoid acidic foods such as tomatoes, lemons, and oranges.
  • Limit alcohol intake and quit smoking.
  • Exercise regularly as it promotes both physical and mental health.
  • Take the necessary precautions to avoid the spread of infection to other people.

Habit Forming

No

Therapeutic Class

ANTIRETROVIRAL AGENTS
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Alcohol

Caution

Avoid drinking alcohol. Consuming alcohol while using Tenfoclear 300 Tablet may worsen the condition.

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Pregnancy

Caution

Tenfoclear 300 Tablet is a category B medicine. It should be used with caution in pregnant women because it may cause side effects to the unborn baby.

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Breast Feeding

Unsafe

The active part of Tenfoclear 300 Tablet may pass with breast milk. Women who are HIV-positive must not breast-feed, because HIV infection can be passed on to the baby in breast milk.

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Driving

Caution

Tenfoclear 300 Tablet may cause dizziness. So, avoid driving or refrain from any activities that require you to alert mentally.

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Liver

Caution

Tenfoclear 300 Tablet should be used with caution in patients with liver diseases. Dose adjustments may be necessary. Patients with liver disease, who are treated with Tenfoclear 300 Tablet , have a higher risk of serious and possibly fatal liver complications.

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Kidney

Unsafe

Tenfoclear 300 Tablet should not be used in adolescents with kidney disease. In other people with severe kidney diseases, Tenfoclear 300 Tablet is given only if clinically needed.

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Children

Unsafe

Tenfoclear 300 Tablet should not be used in children below 12 years of age.

Have a query?

FAQs

Tenfoclear 300 Tablet is used to treat HIV and chronic hepatitis B infection.

In the case of HIV infection, Tenfoclear 300 Tablet may decrease the risk of spreading the virus to others, but the risks of infecting others still continue. Although, in the case of hepatitis B virus infection, Tenfoclear 300 Tablet has not proven to decrease the risk of transferring the virus to others. Thereby, the patients of both HIV infection and hepatitis B virus (HBV) infection should not share needles and should practice safe sex.

Tenfoclear 300 Tablet is safe if used in the dose and duration recommended by your doctor. Take it exactly as directed and do not skip any dose. Follow your doctor's guidelines carefully and inform your doctor if any of the side effects disturb you.

Duration of treatment will depend on the seriousness of hepatitis B virus infection. You will require to take regular blood tests to keep a check on the viral load. Your doctor will then decide the duration of the Tenfoclear 300 Tablet appropriately. In a few cases, treatment is needed lifelong.

Tenfoclear 300 Tablet works by prevents the development of viruses in human cells. This prevents the virus from producing new viruses and cleans up your infection. It can effectively reduce the symptoms associated with HIV and chronic hepatitis B infection.

The main symptoms include yellowing of eyes and skin, flu-like symptoms, pale stools and dark-colored urine.

Tenfoclear 300 Tablet does not prevent the chance of transmission of new virus infection. Therefore, always take necessary precautions as per national guidelines for the prevention of transmission of new virus infection.

If you have Tuberculosis, HIV-1 virus infection or any other medical condition, you are recommended to inform your doctor before taking Tenfoclear 300 Tablet .

You should take Tenfoclear 300 Tablet in the dose and duration prescribed by your doctor. Take Tenfoclear 300 Tablet with or without food as advised by the doctor. Swallow it as a whole with a glass of water. Do not crush, chew or break it.

If you vomit within 1 hour of taking Tenfoclear 300 Tablet , take another one. However, you need not take another tablet if you vomit after more than an hour of taking Tenfoclear 300 Tablet . If you experience vomiting whenever you take Tenfoclear 300 Tablet or if the vomiting persists for a longer duration, consult your doctor.

If you forget to take Tenfoclear 300 Tablet within 12 hours of your usual dosing time, you should take it with food as soon as possible and go back to the normal dosing schedule. If you miss a dose of Tenfoclear 300 Tablet by more than 12 hours and it is almost time for your next dose, you should skip the missed dose and simply resume the regular dosing schedule.

The side effects of Tenfoclear 300 Tablet include nausea, diarrhoea, rash, weakness, and stomach pain. If any of these side effects persist or worsen, please consult your doctor.

Country of origin

INDIA

Manufacturer/Marketer address

401, Lsc, C-Block, Mohan Place Saraswati Vihar Delhi Dl 110034 In
Other Info - TEN0281

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