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compositionComposition:TENECTEPLASE-50MG
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Tenecterel 50 mg Injection 1's is a clot-busting drug indicated to reduce the risk of death in people who have had a severe type of heart attack known as acute ST-elevation myocardial infarction (STEMI). It contains Tenecteplase, which helps to dissolve unwanted blood clots in the heart's blood vessels. Thus, it helps to prevent damage caused by heart attacks and has been shown to save lives.

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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

TENECTEPLASE-50MG

Manufacturer/Marketer :

Reliance Life Sciences Pvt Ltd

Consume Type :

Parenteral

Expires on or after :

Dec-28

Return Policy :

Not Returnable

About Tenecterel 50 mg Injection 1's

Tenecterel 50 mg Injection 1's is a specialised injection used to treat a sudden, acute heart attack by dissolving blood clots that block blood flow to the heart. It is given as an emergency medical treatment to help restore normal blood circulation as quickly as possible. By clearing the blocked artery, this medicine helps minimise permanent damage to the heart muscle.

Because this medicine is an emergency treatment, it is given as a single, one-time injection rather than on a regular daily schedule. It is injected directly into a vein, so it does not require any food considerations. After emergency recovery, adopting a heart-healthy diet low in salt and saturated fats, along with regular physical activity, is crucial to support long-term heart health.

Common side effects of this medication include minor bleeding from the injection site, bruising, and nosebleeds. You must inform your doctor immediately if you experience serious side effects, such as severe internal bleeding or sudden difficulty speaking or moving.

Do not receive this medicine if you have active internal bleeding, a history of stroke, severe uncontrolled high blood pressure, or if you have recently had major surgery. Talk to your doctor to ensure this treatment is safe for your specific condition before it is given.

This injection can interact with blood thinners and other medications, which can significantly increase your risk of bleeding. If you are pregnant, breastfeeding, or are an older adult, discuss the potential risks and benefits with your doctor before receiving this treatment.

Uses of Tenecterel 50 mg Injection 1's

Tenecterel 50 mg Injection 1's is used as an emergency treatment to rapidly dissolve blood clots and restore blood flow to the heart. It may be prescribed for the following condition:

  • Acute Heart Attack: Tenecterel 50 mg Injection 1's is used to dissolve dangerous blood clots in the coronary arteries, restoring vital oxygen and blood flow to the heart muscle to prevent further tissue damage.

Key Benefits

Tenecterel 50 mg Injection 1's provides important benefits by restoring blood flow quickly during a heart attack and supporting better recovery outcomes:

  • Rapid clot dissolution: Quickly breaks down the blood clot blocking the coronary artery, helping restore oxygen-rich blood flow to the heart muscle.
  • Limits heart muscle damage: Early treatment reduces the extent of permanent damage to the heart, improving the chances of recovery and preserving heart function.
  • Improves survival and recovery: Prompt restoration of blood flow reduces the risk of serious complications associated with acute heart attacks.
  • Convenient single-bolus administration: Unlike some older clot-dissolving medicines that require prolonged infusions, Tenecterel 50 mg Injection 1's is administered as a single intravenous injection, allowing faster treatment during emergencies.

Directions for Use

  • Follow your doctor’s instructions on the dosage and timing of this medication to ensure safe and effective use.
  • Tenecterel 50 mg Injection 1's will be administered by the doctor or healthcare professional in a medical setting.
  • Do not self-administer.

How Tenecterel 50 mg Injection 1's Works

Tenecterel 50 mg Injection 1's contains tenecteplase, a thrombolytic medicine that helps dissolve blood clots and restore blood flow to the heart. Tenecterel 50 mg Injection 1's works by attaching to fibrin, a protein that forms the structural framework of a blood clot. Once bound to the clot, it activates plasmin, a naturally occurring enzyme in the blood that breaks down fibrin. This process dissolves the clot, allowing blood to flow freely through the affected blood vessel. By restoring blood flow to the heart muscle, Tenecterel 50 mg Injection 1's helps limit damage caused by a heart attack and improves the supply of oxygen and nutrients to the affected tissue. Together, these actions help dissolve blood clots, restore normal blood circulation, and reduce damage to the heart following an acute heart attack.
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Alcohol

Not applicable

Tenecterel 50 mg Injection 1's is administered to hospitalized patients.

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Pregnancy

Consult your doctor

Limited data is available on the effect of Tenecterel 50 mg Injection 1's in pregnant women. If you are pregnant or planning pregnancy, inform your doctor before receiving Tenecterel 50 mg Injection 1's. Your doctor may give this medicine if the benefits outweigh the risks.

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Breast Feeding

Consult your doctor

It is unknown whether Tenecteplase is excreted in breast milk. Hence, if you are a nursing mother, inform your doctor before receiving Tenecterel 50 mg Injection 1's. Your doctor may give this medicine if the benefits outweigh the risks.

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Driving

Not applicable

Tenecterel 50 mg Injection 1's is administered to hospitalized patients.

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Liver

Consult your doctor

The effect of liver impairment on the actions of Tenecterel 50 mg Injection 1's in humans has not been particularly studied. However, if you have severe liver failure, inform your doctor before receiving Tenecterel 50 mg Injection 1's.

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Kidney

Consult your doctor

The effect of kidney impairment on the actions of Tenecterel 50 mg Injection 1's in humans has not been particularly studied. However, if you have severe kidney problems, inform your doctor before receiving Tenecterel 50 mg Injection 1's.

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Children

Unsafe

Tenecterel 50 mg Injection 1's is not recommended for children below 18 years of age as the safety and effectiveness were not established.

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Heart

Safe if prescribed

Tenecterel 50 mg Injection 1's is used to treat certain heart attacks by dissolving clots and restoring blood flow. However, it should be avoided in patients with heart problems unless absolutely necessary and under strict medical supervision.

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Geriatrics

Caution

Tenecterel 50 mg Injection 1's may be used in geriatric patients for treating certain heart attacks, but only under strict medical supervision. Due to increased bleeding risks and age-related health concerns, careful assessment and monitoring are essential.

What if I have taken an overdose of Tenecterel 50 mg Injection 1's

Because this medication is prepared and injected by medical experts, an overdose is highly unlikely. However, if an excess amount is injected, it can increase the risk of severe bleeding. Hospital staff will monitor you closely and are fully equipped to manage and treat any bleeding complications immediately.

Diet & Lifestyle Advise

  • Eat a heart-healthy diet: Focus on foods low in saturated fats, trans fats, and cholesterol. Increase your intake of fresh vegetables, fruits, whole grains, and lean proteins.
  • Reduce salt intake: Limit sodium in your meals to help manage your blood pressure and reduce strain on your heart.
  • Avoid tobacco: Quit smoking and avoid secondhand smoke, as nicotine constricts blood vessels and worsens heart health.
  • Gradually resume activity: Work closely with your healthcare team or a cardiac rehabilitation program to safely restart physical exercise.
  • Manage stress: Practice stress-reduction techniques such as deep breathing, meditation, or gentle yoga to protect your heart.
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How Soon It Starts Working

The time required for Tenecterel 50 mg Injection 1's to start to work: Tenecterel 50 mg Injection 1's ideally shows its action within 30 minutes after administration. The time for which the effects of Tenecterel 50 mg Injection 1's last: The effect of Tenecterel 50 mg Injection 1's lasts for 2 hours.

What if you forget to take Tenecterel 50 mg Injection 1's

Since this medicine is given as a single emergency injection by a healthcare professional in a hospital setting, it is not possible to miss a dose.

Storage

• Unopened vials of Tenecterel 50 mg Injection 1's should be stored at controlled room temperature below 30°C (86°F) or kept in a refrigerator between 2°C to 8°C (36°F to 46°F).
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Keep Refrigerated. Do not freeze.

Drug Warnings

  • Inform your healthcare team about recent injuries: Tell your doctor if you have had any recent falls, head injuries, surgery, or bleeding problems before receiving the injection.
  • Check the medicine before administration: Your healthcare provider should ensure the reconstituted solution is clear and colourless to pale yellow before it is administered.
  • Limit unnecessary movement: Remain in bed or move only with assistance after the injection to reduce the risk of falls, bruising, or bleeding.
  • Avoid unnecessary injections and procedures: Intramuscular injections and non-urgent invasive procedures should be avoided for several hours after treatment to minimise bleeding.
  • Report warning symptoms immediately: Tell your doctor or nurse at once if you develop a severe headache, dizziness, confusion, weakness, or any unusual bleeding after treatment.

verifiedApollotooltip

The following medicines may increase the risk of bleeding or require careful monitoring when used with Tenecterel 50 mg Injection 1's:

  • Blood thinners (such as heparin or warfarin): May significantly increase the risk of serious internal bleeding.
  • Antiplatelet drugs (such as aspirin or clopidogrel): Can increase the risk of bleeding when present in the body at the same time as this medicine.
  • Pain relievers (NSAIDs like ibuprofen or naproxen): May increase bleeding risks and should be avoided immediately after treatment unless advised by your doctor.

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verifiedApollotooltip

No clinically significant food interactions are known with Tenecterel 50 mg Injection 1's when used as directed.

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Habit Forming

No

Therapeutic Class

[THROMBOLYTIC ENZYME]

FAQs

No. Tenecterel 50 mg Injection 1's must only be administered as an intravenous (IV) injection by a trained healthcare professional in a hospital or emergency medical setting where your heart and vital signs can be continuously monitored. Do not self-administer this medicine. Talk to your doctor or pharmacist if you would like more information about emergency cardiac care.
Tenecterel 50 mg Injection 1's is an emergency injection used to dissolve blood clots that cause an acute heart attack, helping to restore normal blood flow to the heart muscle. Talk to your doctor if you have questions about your recovery plan.
The most serious risk is severe bleeding, including bleeding inside the brain (stroke) or internal bleeding in the stomach or intestines. Your medical team will monitor you closely to minimise these risks. Talk to your doctor if you have concerns.
This medicine is typically only used during pregnancy if the potential benefit justifies the risk to the unborn baby, as it can increase the risk of bleeding. Talk to your doctor to understand the risks and benefits in emergency situations.
Unlike daily blood thinners that prevent new clots from forming, Tenecterel 50 mg Injection 1's is an emergency "clot-buster" designed to actively dissolve an existing clot that is blocking blood flow. Talk to your doctor or pharmacist for more information.
Your doctor will determine exactly when it is safe to start or resume taking aspirin or other blood thinners after your injection. Do not take any medication without consulting your healthcare team first. Talk to your doctor for personalised advice.
If you notice any unusual bleeding, severe bruising, or blood in your urine or stool after being discharged, seek emergency medical care immediately. Talk to your doctor or pharmacist if you have questions about post-discharge safety.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

Surya Tower, 3rd Floor, Mall Road, Ludhiana - 141 001
Other Info - TEN1219
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