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compositionComposition:TEMOZOLOMIDE-20MG
prescriptionPrescription Medicine
Temoloz-20 Capsule 5's is an anti-cancer medicine used in the treatment of brain tumours such as glioblastoma multiforme (a type of tumour that grows and spreads rapidly) in adults and malignant glioma, including glioblastoma multiforme or anaplastic astrocytoma. This medicine works by inhibiting the production of DNA (deoxyribonucleic acid-genetic material of the cell), thereby affecting cell growth and division. Common side effects include loss of appetite, anxiety, confusion, headache, vomiting, nausea, diarrhoea, constipation, muscle weakness, muscle aches, and fever.
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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
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More about the Product

Composition :

TEMOZOLOMIDE-20MG

Manufacturer/Marketer :

Zuvius Lifesciences Pvt Ltd

Consume Type :

Oral

Return Policy :

Not Returnable

About Temoloz-20 Capsule 5's

Temoloz-20 Capsule 5's belongs to a class of medicines called 'anti-cancer/ antitumor agent', used to treat specific forms of brain tumours such as glioblastoma multiforme (a type of tumour that grows and spreads rapidly) in adults and malignant glioma, including glioblastoma multiforme or anaplastic astrocytoma (a rare malignant brain tumour) in patients older than 3years. A brain tumour is an uncontrolled and unregulated proliferation of cells in the brain. 

Temoloz-20 Capsule 5's contains Temozolomide which works by inhibiting the production of DNA (deoxyribonucleic acid-genetic material of the cell), thereby affecting cell growth and division. Thus, Temoloz-20 Capsule 5's prevents tumours from growing.

Take Temoloz-20 Capsule 5's as prescribed. In some cases, Temoloz-20 Capsule 5's may cause loss of appetite, anxiety, confusion, headache, vomiting, nausea, diarrhoea, constipation, muscle weakness, muscle aches, and fever. Most of these side effects of Temoloz-20 Capsule 5's do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Let your doctor know if you are allergic to any of the contents. Temoloz-20 Capsule 5's is not recommended for patients with severe bone marrow depression or significant bleeding. Avoid taking Temoloz-20 Capsule 5's if you are pregnant or breastfeeding. Both women and men using Temoloz-20 Capsule 5's should use birth control to avoid pregnancy and fathering a child. It would be best not to drive and/or operate machines that require alertness as Temoloz-20 Capsule 5's may cause tiredness or sleepiness.

Uses of Temoloz-20 Capsule 5's

Temoloz-20 Capsule 5's is used in the treatment of Brain tumour. The detailed uses of Temoloz-20 Capsule 5's are as follows:

  • Treat brain tumors and certain cancers: Temoloz-20 Capsule 5's is primarily used to manage aggressive brain cancers such as glioblastoma multiforme and anaplastic astrocytoma. It may also be prescribed for other cancers including melanoma, multiple myeloma, breast cancer, and lung cancer.
  • Disrupt cancer cell growth and DNA replication: Temoloz-20 Capsule 5's works as an alkylating agent, meaning it damages the DNA of cancer cells, preventing them from multiplying and leading to their destruction.
  • Used in combination with radiotherapy or as maintenance therapy: Temoloz-20 Capsule 5's is often given alongside radiation treatment in newly diagnosed cases, followed by cycles of maintenance therapy to prevent recurrence.

Key Benefits

Temoloz-20 Capsule 5's belongs to a class of medicines called anti-cancer/antitumor agents used to treat specific forms of brain tumours such as glioblastoma multiforme (a type of tumour that grows and spreads rapidly) in adults and malignant glioma, including glioblastoma multiforme or anaplastic astrocytoma (a rare malignant brain tumour) in patients older than 3years. It contains Temozolomide which works by binding to the DNA (deoxyribonucleic acid-genetic material of the cell) and interfering with cell growth and division. Thus, Temoloz-20 Capsule 5's prevents tumours from growing.

Directions for Use

  • Temoloz-20 Capsule 5's can be taken with or without food, or as directed by your doctor. To minimize potential side effects like nausea and vomiting, it is recommended to take Temoloz-20 Capsule 5's consistently either on an empty stomach or with meals.
  • Temoloz-20 Capsule 5's is usually taken once daily; however, follow your doctor's instructions regarding dosage and timing to ensure optimal effectiveness.
  • Swallow Temoloz-20 Capsule 5's as a whole with a glass of water.
  • Do not crush, chew, or break Temoloz-20 Capsule 5's, as this may impact absorption.

How Temoloz-20 Capsule 5's Works

Temoloz-20 Capsule 5's contains Temozolomide which works by inhibiting the production of DNA (deoxyribonucleic acid-genetic material of the cell), thereby affecting cell growth and division. Thus, Temoloz-20 Capsule 5's prevents tumours from growing.
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Alcohol

Caution

You are recommended to avoid alcohol consumption while taking Temoloz-20 Capsule 5's. It could lead to unpleasant side effects.

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Pregnancy

Caution

Please consult your doctor if you have any concerns about this. Temoloz-20 Capsule 5's should not be used during pregnancy unless prescribed by your doctor. Women of childbearing potential must use effective contraception during the treatment and for 6months after completion of the treatment.

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Breast Feeding

Unsafe

Temoloz-20 Capsule 5's should not be taken during breastfeeding as it passes into the breastmilk and may harm the baby.

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Driving

Caution

Temoloz-20 Capsule 5's may make you feel tired or sleepy. Drive and/or operate machines only if you are alert.

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Liver

Caution

If you have had a history or evidence of any liver-related diseases, please consult the doctor before using Temoloz-20 Capsule 5's. Your doctor will weigh the benefits and potential risks before prescribing Temoloz-20 Capsule 5's.

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Kidney

Caution

If you have had a history or evidence of any kidney-related diseases, please consult the doctor before using Temoloz-20 Capsule 5's. Your doctor will weigh the benefits and potential risks before prescribing Temoloz-20 Capsule 5's.

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Children

Caution

Safety and effectiveness of Temoloz-20 Capsule 5's in paediatric patients under the age of three have not been established.

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Heart

Caution

Temoloz-20 Capsule 5's should be taken with caution in patients with heart problems. Therefore, please talk to your doctor before using Temoloz-20 Capsule 5's.

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Geriatrics

Caution

Temoloz-20 Capsule 5's should be given with caution in elderly patients due to an increased risk of side effects. It is important to inform a healthcare professional before use.

What if I have taken an overdose of Temoloz-20 Capsule 5's

Do not take more than the prescribed dose of Temoloz-20 Capsule 5's as it may cause overdose. The symptoms of overdose include unusual bleeding or bruising; red/black/tarry stools; red/dark brown/pink urine; coughing up or vomiting blood or material that looks like coffee grounds; sore throat, fever, ongoing congestion and cough, or other signs of infection. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Diet & Lifestyle Advise

  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
  • Performing yoga may also help in improving both physical and mental health.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, and herbs in your diet.
  • Get optimal sleep; rest well.
  • Avoid smoking and alcohol consumption.
  • Avoid fast food, fried food, processed meats, refined carbs and added sugars.

Have a query?

How Soon It Starts Working

The time required for Temoloz-20 Capsule 5's to start to work: The exact onset time of Temoloz-20 Capsule 5's has not been clinically established. The time for which the effects of Temoloz-20 Capsule 5's last: The duration of Temoloz-20 Capsule 5's’s effect is clinically not established.

What if you forget to take Temoloz-20 Capsule 5's

Take the missed dose as soon as you remember. If it is almost time for the next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for the missed dose.

Storage

• Store in a cool and dry place away from sunlight. • Keep Temoloz-20 Capsule 5's out of the sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

Temoloz-20 Capsule 5's should be taken under strict medical supervision. The doctor will regularly monitor your condition while taking Temoloz-20 Capsule 5's. To treat your condition effectually, continue taking Temoloz-20 Capsule 5's for as long as your doctor has prescribed. Do not stop Temoloz-20 Capsule 5's midway under any circumstances without consulting the healthcare professional. Inform your doctor if you have an allergy to any components of Temoloz-20 Capsule 5's. Inform your doctor before taking Temoloz-20 Capsule 5's if you have allergic reactions, infections, lung, renal or hepatic disorders or low blood count (including neutropenia, lymphopenia, thrombocytopenia). Temoloz-20 Capsule 5's is not recommended for patients with severe bone marrow depression or significant bleeding. Avoid taking Temoloz-20 Capsule 5's if you are pregnant or breastfeeding. Both women and men using Temoloz-20 Capsule 5's should use birth control to avoid pregnancy or fathering a child. Do not receive any vaccinations or immunizations without your doctor's approval while taking Temoloz-20 Capsule 5's.

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Drug-Drug Interactions: Temoloz-20 Capsule 5's interacts with medicines used to treat infections (e.g. adalimumab), medicines used to treat rheumatoid arthritis (e.g. baricitinib, certolizumab, golimumab, infliximab, leflunomide, upadacitinib), medicines used to treat certain cancers (e.g. cladribine), medicines used to treat mental/mood disorders (e.g. clozapine), medicines used to treat multiple sclerosis (e.g. fingolimod, siponimod, teriflunomide),  cholesterol-lowering medications (e.g. lomitapide), and vaccines (e.g. BCG vaccine, influenza virus vaccine, measles virus vaccine, rotavirus vaccine, rubella virus vaccine smallpox vaccine, typhoid vaccine, varicella virus vaccine, yellow fever vaccine, zoster vaccine).

Drug-Food Interactions: Avoid the consumption of alcohol while taking Temoloz-20 Capsule 5's.

Drug-Disease Interactions: Inform your doctor before taking the Temoloz-20 Capsule 5's you are suffering from urticaria or allergic reactions, bleeding disorders, myelosuppression (bone marrow depression), low blood counts, hepatic or renal dysfunction or disorders.

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTINEOPLASTIC]

FAQs

Temoloz-20 Capsule 5's belongs to a class of medicines called anti-cancer agents, used to treat specific forms of brain tumours such as glioblastoma multiforme (a type of tumour that grows and spreads rapidly) in adults and malignant glioma, including glioblastoma multiforme or anaplastic astrocytoma (a rare malignant brain tumour) in patients older than 3years.

Temoloz-20 Capsule 5's works by binding to the DNA (deoxyribonucleic acid-genetic material of the cell) and interfering with cell growth and division. Thus, Temoloz-20 Capsule 5's prevents tumours from growing.

Temoloz-20 Capsule 5's may cause permanent infertility. Male patients should use effective contraception and refrain from fathering a child for up to three months after treatment is completed. Prior to treatment, it is recommended to seek sperm conservation advice from your doctor.

Yes, Temoloz-20 Capsule 5's can cause neutropenia (low white blood cells count), lymphopenia (low lymphocytes count), thrombocytopenia (low platelet count). As a part of therapy, your doctor may monitor your blood profile.

Temoloz-20 Capsule 5's may lead to hyperglycemia (Increased blood sugar). Consult your doctor if you are diabetic. Regularly monitor your blood sugar levels while taking Temoloz-20 Capsule 5's.

The live vaccine may interact with Temoloz-20 Capsule 5's. Do not have vaccinations or immunisations without talking to your doctor first.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

B/108-113, Kanara Business Centre Near Everest Gardens, Link Rd, Mumbai, Maharashtra 400075
Other Info - TEM0342
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