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  3. Tegafi Capsule 14'S

Tegafi Capsule 14'S, Pack of 14 CAPSULES
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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Tegafi Capsule is an anti-cancer medicines indicated for first-line treatment of metastatic colorectal cancer. It contains Tegafur and Uracil, which work by interfering with the growth and multiplication of cancer cells. Thereby, it helps treat cancer. In some cases, this medication may cause side effects such as diarrhoea, nausea, vomiting, and abdominal pain. This medicine is not recommended for children as safety and effectiveness have not been established.

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Composition :

TEGAFUR-100MG + URACIL-224MG

Manufacturer/Marketer :

Intas Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Tegafi Capsule

Tegafi Capsule belongs to the group of anti-cancer medicines indicated with calcium folinate for the first-line treatment of metastatic colorectal cancer. Colorectal cancer is a disease in which the cells in the colon or rectum grow out of control.

Tegafi Capsule contains Tegafur and Uracil, which work by interfering with the growth and multiplication of cancer cells. Thereby, it helps treat cancer.

In some cases, Tegafi Capsule may cause side effects such as diarrhoea, nausea, vomiting, and abdominal pain. Most of these side effects may not require medical attention and resolve gradually over time. Do not be reluctant to talk with your doctor if any of the side effects persist or worsen.

Do not take Tegafi Capsule if you are pregnant or breastfeeding. This medicine is not recommended for children as safety and effectiveness have not been established. Keep the doctor informed about your health condition and medications to rule out any side effects/interactions.

Uses of Tegafi Capsule

Tegafi Capsule is used in the treatment of colorectal cancer (cancer of the colon and rectum). The detailed uses of Tegafi Capsule are as follows:<br/>• Treats colon and rectal cancer: Tegafi Capsule helps stop the growth and spread of cancer cells, especially in patients undergoing chemotherapy for colorectal cancer.<br/>• Reduces risk of cancer recurrence: Tegafi Capsule may lower the chances of developing new cancerous growths after initial treatment or surgery.<br/>• Supports recovery during chemotherapy: Tegafi Capsule helps improve the effectiveness of chemotherapy while minimizing some of its side effects, leading to a more comfortable treatment experience.<br/>

Directions for Use

• Follow your doctor's instructions on the dosage and timing of this medication, to improve effectiveness.• Take the medicine an hour before or after food or as advised by the doctor.• Swallow the medicine as a whole with a glass of water.• Do not crush, break or chew it.

Medicinal Benefits

Tegafi Capsule belongs to the group of anti-cancer medicines indicated for the first-line treatment of metastatic colorectal cancer with calcium folinate. Tegafi Capsule contains Tegafur and Uracil, which work by interfering with the growth and multiplication of cancer cells. Thus, it helps treat cancer.

How Tegafi Capsule Works

Tegafi Capsule contains Tegafur and Uracil, which work by interfering with the growth and multiplication of cancer cells. Thereby, it helps treat cancer.

Storage

• Store in a cool and dry place away from sunlight.• Keep Tegafi Capsule out of reach and sight of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of Tegafi Capsule

Do not take more than the prescribed dose of Tegafi Capsule , as it may cause an overdose. Overdosage could lead to fatal complications. Anticipated manifestations might include nausea, vomiting, diarrhoea, gastrointestinal ulceration and bleeding, bone marrow suppression (including leukopenia, thrombocytopenia and agranulocytosis). Contact your doctor immediately if you experience these or think you have taken too much.

Drug Warnings

Do not take Tegafi Capsule if you are allergic to any of its components or if you are pregnant or breastfeeding. Consult the doctor immediately if you become pregnant during treatment with Tegafi Capsule . Tegafi Capsule is not recommended for children, paediatrics and adolescents. Inform the doctor if you experience symptoms of infection (fever or sudden unwell feeling), unexplained bleeding or bruising (bleeding gums, nose bleeds, rashes or blood spots on the skin), anaemia (tiredness and breathlessness) or conjunctivitis (sore and inflamed eyes). Let the doctor know if you take other medicines, including supplements or herbal products.

Diet & Lifestyle Advise

  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Avoid smoking and alcohol consumption.
  • Include vegetables and fruits in your diet.
  • Avoid fast food, fried food, processed meats, refined carbs and added sugar.
  • Get optimal sleep; rest well.
  • Drink enough water to stay hydrated.

Habit Forming

No

Therapeutic Class

CHEMOTHERAPY

Tegafi Capsule Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Consult your doctor

It is not known if alcohol affects Tegafi Capsule . Please consult your doctor.

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Pregnancy

Unsafe

Tegafi Capsule is not recommended during pregnancy as it may cause foetal harm. Women with childbearing potential are advised to avoid becoming pregnant during treatment with Tegafi Capsule .

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Breast Feeding

Unsafe

This medicine may pass into breast milk. Breastfeeding is not recommended during treatment with Tegafi Capsule and for a few months afterwards.

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Driving

Caution

Tegafi Capsule may cause tiredness. Avoid driving or operating machinery if you experience any side effects that might lessen your ability to do so.

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Liver

Caution

When Tegafi Capsule is used, patients with mild to moderate hepatic dysfunction should be closely monitored by liver function tests.

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Kidney

Consult your doctor

In patients with renal impairment, Tegafi Capsule has not been used extensively. When using this medicine in such patients, physicians ought to proceed with caution.

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Children

Unsafe

Tegafi Capsule is not recommended for children as safety and effectiveness have not been established.

Have a query?

FAQs

Tegafi Capsule is used to treat Colorectal cancer.

Tegafi Capsule works by interfering with the growth and multiplication of cancer cells. Thereby, it helps treat cancer.

Tegafi Capsule may cause diarrhoea in some cases. Drink plenty of fluids if you have diarrhoea. Consult the doctor if you experience severe diarrhoea; your doctor may initiate supportive care or interrupt medication based on your condition. In patients with severe diarrhoea, careful monitoring and fluid and electrolyte replacement are recommended to prevent dehydration.

Tegafi Capsule may reduce the number of white blood cells, which help fight infections. This might increase the risk of infections. Consult the doctor if you experience symptoms of infection, such as a fever, or if you suddenly feel unwell.

Tegafi Capsule may affect your ability to become pregnant or father a child. Prior to the start of the treatment, discuss with your doctor if you have any concerns about fertility.

Country of origin

India

Manufacturer/Marketer address

Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.
Other Info - TEG0092

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Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 18, 2025 | 7:07 AM IST

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Reference

  1. https://hemonc.org/docs/packageinsert/uraciltegafur.pdf
  2. https://www.pharmadoor.com.br/images/medicamentos/bulas/Bula_Tegafur.pdf

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